Page last updated: 2024-11-07

oxandrolone and Down Syndrome

oxandrolone has been researched along with Down Syndrome in 3 studies

Oxandrolone: A synthetic hormone with anabolic and androgenic properties.

Down Syndrome: A chromosome disorder associated either with an extra chromosome 21 or an effective trisomy for chromosome 21. Clinical manifestations include hypotonia, short stature, brachycephaly, upslanting palpebral fissures, epicanthus, Brushfield spots on the iris, protruding tongue, small ears, short, broad hands, fifth finger clinodactyly, Simian crease, and moderate to severe INTELLECTUAL DISABILITY. Cardiac and gastrointestinal malformations, a marked increase in the incidence of LEUKEMIA, and the early onset of ALZHEIMER DISEASE are also associated with this condition. Pathologic features include the development of NEUROFIBRILLARY TANGLES in neurons and the deposition of AMYLOID BETA-PROTEIN, similar to the pathology of ALZHEIMER DISEASE. (Menkes, Textbook of Child Neurology, 5th ed, p213)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19903 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
RAY, CG2
KIRSCHVINK, JF2
WAXMAN, SH2
KELLEY, VC3
Ruvalcaba, RH1
Limbeck, GA1
Tattoni, DS1
Moore, DC1

Trials

1 trial available for oxandrolone and Down Syndrome

ArticleYear
Studies of anabolic steroids. VIII. Adult stature of males with Down syndrome treated with oxandrolone during childhood.
    The Journal of pediatrics, 1976, Volume: 88, Issue:3

    Topics: Body Height; Child; Down Syndrome; Follow-Up Studies; Humans; Male; Oxandrolone

1976

Other Studies

2 other studies available for oxandrolone and Down Syndrome

ArticleYear
STUDIES OF ANABOLIC STEROIDS. II. THE EFFECT OF OXANDROLONE ON HEIGHT AND SKELETAL MATURATION IN MONGOLOID CHILDREN (A PRELIMINARY REPORT).
    American journal of diseases of children (1960), 1963, Volume: 106

    Topics: Adolescent; Aging; Anabolic Agents; Body Height; Body Weight; Child; Down Syndrome; Epiphyses; Growt

1963
Studies of anabolic steroids. 3. The effect of oxandrolone on height and skeletal maturation in mongoloid children.
    American journal of diseases of children (1960), 1965, Volume: 110, Issue:6

    Topics: Adolescent; Age Determination by Skeleton; Body Height; Child; Child, Preschool; Down Syndrome; Fema

1965