Page last updated: 2024-11-07

oxandrolone and Bed Sores

oxandrolone has been researched along with Bed Sores in 7 studies

Oxandrolone: A synthetic hormone with anabolic and androgenic properties.

Research Excerpts

ExcerptRelevanceReference
"To determine whether oxandrolone increases the percentage of target pressure ulcers (TPUs) that heal compared with placebo and whether healed ulcers remain closed 8 weeks after treatment."9.17The effect of oxandrolone on the healing of chronic pressure ulcers in persons with spinal cord injury: a randomized trial. ( Bauman, WA; Chua, WC; Collins, JF; Deitrick, GA; Goetz, LL; Ho, C; Holmes, SA; Jayawardena, V; Merritt, JL; Nasar, F; Nemchausky, BA; Park, JS; Punj, V; Raisch, DW; Sabharwal, S; Sandford, P; Sasaki, R; Schwartz, M; Spungen, AM; Thomas, MD; Trincher, RC; Zachow, KF, 2013)
"To determine whether oxandrolone increases the percentage of target pressure ulcers (TPUs) that heal compared with placebo and whether healed ulcers remain closed 8 weeks after treatment."5.17The effect of oxandrolone on the healing of chronic pressure ulcers in persons with spinal cord injury: a randomized trial. ( Bauman, WA; Chua, WC; Collins, JF; Deitrick, GA; Goetz, LL; Ho, C; Holmes, SA; Jayawardena, V; Merritt, JL; Nasar, F; Nemchausky, BA; Park, JS; Punj, V; Raisch, DW; Sabharwal, S; Sandford, P; Sasaki, R; Schwartz, M; Spungen, AM; Thomas, MD; Trincher, RC; Zachow, KF, 2013)
"A case of pressure ulcer in a 25-year-old male patient with the neurodegenerative disorder giant axonal neuropathy (GAN) was safely and effectively treated with an eight-week regimen of oxandrolone and nutritional supplementation."3.76Success of oxandrelone in the treatment of decubitus ulcers. ( Forman, SB; Madden, KB; Stampas, A, 2010)
"Pressure ulcers, also known as bed sores, pressure sores or decubitus ulcers develop as a result of a localised injury to the skin or underlying tissue, or both."2.55Anabolic steroids for treating pressure ulcers. ( Naing, C; Whittaker, MA, 2017)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (14.29)29.6817
2010's6 (85.71)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Naing, C1
Whittaker, MA1
Bauman, WA1
Spungen, AM1
Collins, JF1
Raisch, DW1
Ho, C1
Deitrick, GA1
Nemchausky, BA1
Goetz, LL1
Park, JS1
Schwartz, M1
Merritt, JL1
Jayawardena, V1
Sandford, P1
Sabharwal, S1
Holmes, SA1
Nasar, F1
Sasaki, R1
Punj, V1
Zachow, KF1
Chua, WC1
Thomas, MD1
Trincher, RC1
Salcido, R1
Madden, KB1
Stampas, A1
Forman, SB1
Mikulin, L1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
CSP #535 - Anabolic Steroid Therapy on Pressure Ulcer Healing in Persons With Spinal Cord Injury[NCT00101361]Phase 3212 participants (Actual)Interventional2005-08-31Terminated (stopped due to futility analysis showed low probability of detecting a significant difference)
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

A Healed Pressure Ulcer

Patients remained in treatment until full healing of the target pressure ulcer (defined as re-epithelialization to a cicatrix with a dry surface and zero open area for a minimum of 96 hours) or 24 weeks, whichever occured first. (NCT00101361)
Timeframe: healing was measured from randomization to full healing or 24 weeks, whichever occured first.

Interventionparticipants (Number)
1 Oxandrolone26
2 Placebo31

Reviews

1 review available for oxandrolone and Bed Sores

ArticleYear
Anabolic steroids for treating pressure ulcers.
    The Cochrane database of systematic reviews, 2017, 06-20, Volume: 6

    Topics: Female; Humans; Male; Middle Aged; Off-Label Use; Oxandrolone; Pressure Ulcer; Starch; Stearic Acids

2017

Trials

1 trial available for oxandrolone and Bed Sores

ArticleYear
The effect of oxandrolone on the healing of chronic pressure ulcers in persons with spinal cord injury: a randomized trial.
    Annals of internal medicine, 2013, May-21, Volume: 158, Issue:10

    Topics: Aged; Anabolic Agents; Female; Humans; Liver; Male; Middle Aged; Oxandrolone; Prealbumin; Pressure U

2013

Other Studies

5 other studies available for oxandrolone and Bed Sores

ArticleYear
Oxandrolone no better than placebo for severe pressure ulcers.
    BMJ (Clinical research ed.), 2013, May-22, Volume: 346

    Topics: Anabolic Agents; Female; Humans; Male; Oxandrolone; Placebo Effect; Pressure Ulcer; Treatment Outcom

2013
Summaries for patients. Oxandrolone treatment for pressure ulcers.
    Annals of internal medicine, 2013, May-21, Volume: 158, Issue:10

    Topics: Aged; Anabolic Agents; Female; Humans; Male; Middle Aged; Oxandrolone; Pressure Ulcer; Spinal Cord I

2013
The use of off-labeled drugs in wound healing: oxandrolone.
    Advances in skin & wound care, 2015, Volume: 28, Issue:12

    Topics: Androgens; Humans; Off-Label Use; Oxandrolone; Pressure Ulcer; Wound Healing

2015
Success of oxandrelone in the treatment of decubitus ulcers.
    Journal of drugs in dermatology : JDD, 2010, Volume: 9, Issue:6

    Topics: Adult; Anabolic Agents; Humans; Male; Oxandrolone; Pressure Ulcer

2010
Nutrition and its role in wound healing.
    Ostomy/wound management, 2001, Volume: 47, Issue:9

    Topics: Adult; Anabolic Agents; Enteral Nutrition; Female; HIV Wasting Syndrome; Humans; Myelitis; Nutrition

2001