Compounds > oxandrolone
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oxandrolone and Alcoholic Hepatitis

oxandrolone has been researched along with Alcoholic Hepatitis in 11 studies

Oxandrolone: A synthetic hormone with anabolic and androgenic properties.

Research Excerpts

ExcerptRelevanceReference
"A Veterans Affairs cooperative study involving 273 male patients was performed to evaluate efficacy of oxandrolone in combination with an enteral food supplement in severe alcoholic hepatitis."9.07A study of oral nutritional support with oxandrolone in malnourished patients with alcoholic hepatitis: results of a Department of Veterans Affairs cooperative study. ( Allen, JI; Marsano, LS; McClain, CJ; Mendenhall, CL; Morgan, TR; Moritz, TE; Nemchausky, BA; Roselle, GA; Schiff, ER; Tamburro, CH, 1993)
"Patients with moderately severe or severe alcoholic hepatitis, described in a companion paper in this issue, had serial studies of energy and protein metabolism and elemental balances before and during treatment for 21 days with one of four randomly assigned regimens: 1) standard therapy, consisting of abstinence, a balanced, nutritionally adequate diet, and multivitamins; 2) oxandrolone (20 mg orally four times a day) plus standard therapy; 3) nutritional supplementation, consisting of 2 liters of 3."9.07A randomized, controlled trial of treatment of alcoholic hepatitis with parenteral nutrition and oxandrolone. II. Short-term effects on nitrogen metabolism, metabolic balance, and nutrition. ( Bonkovsky, HL; Cotsonis, GA; Fiellin, DA; Jafri, IH; Simon, D; Singh, RH; Slaker, DP; Smith, GS, 1991)
"The present studies were designed to provide careful measures of effects of oxandrolone, an anabolic steroid, intravenous nutritional supplementation, and the combination of these two treatments on liver functions, metabolic balances, nitrogen metabolism, and nutritional status in patients with moderate to severe alcoholic hepatitis."9.07A randomized, controlled trial of treatment of alcoholic hepatitis with parenteral nutrition and oxandrolone. I. Short-term effects on liver function. ( Bonkovsky, HL; Fiellin, DA; Galambos, JT; Simon, D; Slaker, DP; Smith, GS, 1991)
"A cooperative study was conducted to determine the efficacy of 30 days of treatment with either a glucocorticosteroid (prednisolone) or an anabolic steroid (oxandrolone) in moderate or severe alcoholic hepatitis."9.05Short-term and long-term survival in patients with alcoholic hepatitis treated with oxandrolone and prednisolone. ( Anderson, S; Garcia-Pont, P; Goldberg, S; Kiernan, T; Mendenhall, CL; Seeff, LB; Sorrell, M; Tamburro, C; Weesner, R; Zetterman, R, 1984)
"A cohort of 273 male patients enrolled in a Department of Veterans Affairs Cooperative Study performed to evaluate the efficacy of oxandrolone in combination with nutritional supplementation in moderate or severe alcoholic hepatitis."5.07Helicobacter pylori is a risk factor for hepatic encephalopathy in acute alcoholic hepatitis: the ammonia hypothesis revisited. The Veterans Administration Cooperative Study Group No. 275. ( Gubbins, GP; Marsano, LS; McClain, CJ; Mendenhall, CL; Moritz, TE; Talwalkar, R, 1993)
"A Veterans Affairs cooperative study involving 273 male patients was performed to evaluate efficacy of oxandrolone in combination with an enteral food supplement in severe alcoholic hepatitis."5.07A study of oral nutritional support with oxandrolone in malnourished patients with alcoholic hepatitis: results of a Department of Veterans Affairs cooperative study. ( Allen, JI; Marsano, LS; McClain, CJ; Mendenhall, CL; Morgan, TR; Moritz, TE; Nemchausky, BA; Roselle, GA; Schiff, ER; Tamburro, CH, 1993)
"Patients with moderately severe or severe alcoholic hepatitis, described in a companion paper in this issue, had serial studies of energy and protein metabolism and elemental balances before and during treatment for 21 days with one of four randomly assigned regimens: 1) standard therapy, consisting of abstinence, a balanced, nutritionally adequate diet, and multivitamins; 2) oxandrolone (20 mg orally four times a day) plus standard therapy; 3) nutritional supplementation, consisting of 2 liters of 3."5.07A randomized, controlled trial of treatment of alcoholic hepatitis with parenteral nutrition and oxandrolone. II. Short-term effects on nitrogen metabolism, metabolic balance, and nutrition. ( Bonkovsky, HL; Cotsonis, GA; Fiellin, DA; Jafri, IH; Simon, D; Singh, RH; Slaker, DP; Smith, GS, 1991)
"The present studies were designed to provide careful measures of effects of oxandrolone, an anabolic steroid, intravenous nutritional supplementation, and the combination of these two treatments on liver functions, metabolic balances, nitrogen metabolism, and nutritional status in patients with moderate to severe alcoholic hepatitis."5.07A randomized, controlled trial of treatment of alcoholic hepatitis with parenteral nutrition and oxandrolone. I. Short-term effects on liver function. ( Bonkovsky, HL; Fiellin, DA; Galambos, JT; Simon, D; Slaker, DP; Smith, GS, 1991)
"A cooperative study was conducted to determine the efficacy of 30 days of treatment with either a glucocorticosteroid (prednisolone) or an anabolic steroid (oxandrolone) in moderate or severe alcoholic hepatitis."5.05Short-term and long-term survival in patients with alcoholic hepatitis treated with oxandrolone and prednisolone. ( Anderson, S; Garcia-Pont, P; Goldberg, S; Kiernan, T; Mendenhall, CL; Seeff, LB; Sorrell, M; Tamburro, C; Weesner, R; Zetterman, R, 1984)
"For prednisolone, the response was seen only when the DF was 81-100 reducing mortality 45% When oxandrolone, an androgenic anabolic steroid treatment was given, efficacy was observed only in those with moderate malnutrition (PCM score 60-79% of normal) and maximized with adequate caloric intake reducing mortality 86%."2.68Relationship of protein calorie malnutrition to alcoholic liver disease: a reexamination of data from two Veterans Administration Cooperative Studies. ( Gartside, P; Mendenhall, C; Moritz, T; Roselle, GA, 1995)
"Alcoholic hepatitis is a frequent reason for admission and a common consultation request for hepatologists and gastroenterologists."2.48Alcoholic hepatitis: a clinician's guide. ( Choi, G; Runyon, BA, 2012)
"In human studies of patients with alcoholic hepatitis, these abnormalities were also seen with specific correlation with protein malnutrition."1.29Alcohol modulation of immune function: clinical and experimental data. Veterans Affairs Cooperative Study Groups 119 and 275. ( Chedid, A; Gartside, P; Mendenhall, CL; Moritz, TE; Roselle, GA, 1995)

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19903 (27.27)18.7374
1990's7 (63.64)18.2507
2000's0 (0.00)29.6817
2010's1 (9.09)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Choi, G1
Runyon, BA1
Mendenhall, CL5
Anderson, S1
Garcia-Pont, P2
Goldberg, S1
Kiernan, T2
Seeff, LB2
Sorrell, M1
Tamburro, C2
Weesner, R1
Zetterman, R2
Roselle, GA3
Chedid, A1
Moritz, TE3
Gartside, P2
Mendenhall, C2
Moritz, T2
Gubbins, GP1
Marsano, LS2
Talwalkar, R1
McClain, CJ2
Morgan, TR2
Nemchausky, BA1
Tamburro, CH1
Schiff, ER1
Allen, JI1
Bonkovsky, HL2
Singh, RH1
Jafri, IH1
Fiellin, DA2
Smith, GS2
Simon, D2
Cotsonis, GA1
Slaker, DP2
Galambos, JT1
Ezzell, JH1
Werkman, RF1
Dean, P1
Tosch, T1
Weesner, RE1
Goldberg, SJ1
Sorell, M1

Reviews

2 reviews available for oxandrolone and Alcoholic Hepatitis

ArticleYear
Alcoholic hepatitis: a clinician's guide.
    Clinics in liver disease, 2012, Volume: 16, Issue:2

    Topics: Adrenal Cortex Hormones; Anabolic Agents; Baclofen; Dietary Supplements; GABA-B Receptor Agonists; H

2012
Treatment of alcoholic hepatitis.
    The American journal of gastroenterology, 1989, Volume: 84, Issue:10

    Topics: Adult; Biopsy; Female; Food, Formulated; Hepatitis, Alcoholic; Humans; Liver; Oxandrolone; Parentera

1989

Trials

7 trials available for oxandrolone and Alcoholic Hepatitis

ArticleYear
Short-term and long-term survival in patients with alcoholic hepatitis treated with oxandrolone and prednisolone.
    The New England journal of medicine, 1984, Dec-06, Volume: 311, Issue:23

    Topics: Clinical Trials as Topic; Follow-Up Studies; Hepatitis, Alcoholic; Humans; Liver; Middle Aged; Oxand

1984
Relationship of protein calorie malnutrition to alcoholic liver disease: a reexamination of data from two Veterans Administration Cooperative Studies.
    Alcoholism, clinical and experimental research, 1995, Volume: 19, Issue:3

    Topics: Adult; Aged; Bilirubin; Creatinine; Double-Blind Method; Hepatitis, Alcoholic; Humans; Liver Functio

1995
Helicobacter pylori is a risk factor for hepatic encephalopathy in acute alcoholic hepatitis: the ammonia hypothesis revisited. The Veterans Administration Cooperative Study Group No. 275.
    The American journal of gastroenterology, 1993, Volume: 88, Issue:11

    Topics: Ammonia; Cohort Studies; Helicobacter Infections; Helicobacter pylori; Hepatic Encephalopathy; Hepat

1993
A study of oral nutritional support with oxandrolone in malnourished patients with alcoholic hepatitis: results of a Department of Veterans Affairs cooperative study.
    Hepatology (Baltimore, Md.), 1993, Volume: 17, Issue:4

    Topics: Alcohol Drinking; Energy Intake; Enteral Nutrition; Hepatitis, Alcoholic; Hospitals, Veterans; Human

1993
Nutritional therapy for alcoholic hepatitis. VA Cooperative 275 Study Group.
    Gastroenterology, 1992, Volume: 103, Issue:1

    Topics: Administration, Oral; Diet; Food, Formulated; Hepatitis, Alcoholic; Humans; Oxandrolone

1992
A randomized, controlled trial of treatment of alcoholic hepatitis with parenteral nutrition and oxandrolone. II. Short-term effects on nitrogen metabolism, metabolic balance, and nutrition.
    The American journal of gastroenterology, 1991, Volume: 86, Issue:9

    Topics: Adult; Amino Acids; Combined Modality Therapy; Energy Metabolism; Female; Hepatitis, Alcoholic; Huma

1991
A randomized, controlled trial of treatment of alcoholic hepatitis with parenteral nutrition and oxandrolone. I. Short-term effects on liver function.
    The American journal of gastroenterology, 1991, Volume: 86, Issue:9

    Topics: Adult; Analysis of Variance; Antipyrine; Cardiac Output; Combined Modality Therapy; Female; Galactos

1991

Other Studies

2 other studies available for oxandrolone and Alcoholic Hepatitis

ArticleYear
Alcohol modulation of immune function: clinical and experimental data. Veterans Affairs Cooperative Study Groups 119 and 275.
    Alcoholism, clinical and experimental research, 1995, Volume: 19, Issue:3

    Topics: Animals; Combined Modality Therapy; Follow-Up Studies; Food, Fortified; Hepatitis, Alcoholic; Humans

1995
VA cooperative study on alcoholic hepatitis. II: Prognostic significance of protein-calorie malnutrition.
    The American journal of clinical nutrition, 1986, Volume: 43, Issue:2

    Topics: Energy Intake; Energy Metabolism; Hepatitis, Alcoholic; Humans; Liver; Oxandrolone; Prednisolone; Pr

1986