Page last updated: 2024-11-07

oxandrolone and Acute Liver Injury, Drug-Induced

oxandrolone has been researched along with Acute Liver Injury, Drug-Induced in 11 studies

Oxandrolone: A synthetic hormone with anabolic and androgenic properties.

Research Excerpts

ExcerptRelevanceReference
" Mortality, infection, and hepatic function: Oxandrolone therapy did not affect mortality (relative risk (RR)=0."8.93The efficacy and safety of oxandrolone treatment for patients with severe burns: A systematic review and meta-analysis. ( Guo, Q; Guo, Y; Li, H; Roy, M; Yang, Z, 2016)
" Mortality, infection, and hepatic function: Oxandrolone therapy did not affect mortality (relative risk (RR)=0."4.93The efficacy and safety of oxandrolone treatment for patients with severe burns: A systematic review and meta-analysis. ( Guo, Q; Guo, Y; Li, H; Roy, M; Yang, Z, 2016)
"Oxandrolone has proven benefits in thermal burn injury and has become a standard of care."1.51Risk Factors Associated with the Development of Transaminitis in Oxandrolone-Treated Adult Burn Patients. ( Foster, CJ; Gayed, RM; Hill, DM; Jones, KM; Kiracofe, B; Murphy, CV; Oltrogge Pape, K; Porter, K; Reger, M; Zavala, S, 2019)
" We proposed a systematic classification scheme using FDA-approved drug labeling to assess the DILI potential of drugs, which yielded a benchmark dataset with 287 drugs representing a wide range of therapeutic categories and daily dosage amounts."1.37FDA-approved drug labeling for the study of drug-induced liver injury. ( Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V, 2011)

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19903 (27.27)18.7374
1990's0 (0.00)18.2507
2000's1 (9.09)29.6817
2010's7 (63.64)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Fourches, D1
Barnes, JC1
Day, NC1
Bradley, P1
Reed, JZ1
Tropsha, A1
Chen, M2
Vijay, V1
Shi, Q2
Liu, Z2
Fang, H2
Tong, W3
Ding, D1
Kelly, R1
Suzuki, A1
Thakkar, S1
Yu, K1
Hu, C1
Kiracofe, B2
Coffey, R1
Jones, LM1
Bailey, JK1
Thomas, S1
Porter, K2
Murphy, CV2
Zavala, S1
Gayed, RM1
Foster, CJ1
Jones, KM1
Oltrogge Pape, K1
Hill, DM1
Reger, M1
Li, H1
Guo, Y1
Yang, Z1
Roy, M1
Guo, Q1
Segal, S1
Cooper, J1
Bolognia, J1
Jackson, ST1
Rallison, ML1
Buntin, WH1
Johnson, SB1
Flynn, RR1
Sansoy, OM1
Roy, AN1
Shields, LM1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Efficacy of Testosterone Gel to Restore Normal Serum Values of Testosterone During the Acute Phase of Critical Illness in Adult ICU Patients[NCT03678233]Phase 230 participants (Anticipated)Interventional2019-06-27Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

2 reviews available for oxandrolone and Acute Liver Injury, Drug-Induced

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Pr

2016
The efficacy and safety of oxandrolone treatment for patients with severe burns: A systematic review and meta-analysis.
    Burns : journal of the International Society for Burn Injuries, 2016, Volume: 42, Issue:4

    Topics: Anabolic Agents; Body Composition; Body Weight; Burns; Chemical and Drug Induced Liver Injury; Human

2016

Other Studies

9 other studies available for oxandrolone and Acute Liver Injury, Drug-Induced

ArticleYear
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLI

2010
FDA-approved drug labeling for the study of drug-induced liver injury.
    Drug discovery today, 2011, Volume: 16, Issue:15-16

    Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Des

2011
Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps).
    PLoS computational biology, 2011, Volume: 7, Issue:12

    Topics: Animals; Anti-Infective Agents; Anti-Inflammatory Agents; Chemical and Drug Induced Liver Injury; Da

2011
Incidence of oxandrolone induced hepatic transaminitis in patients with burn injury.
    Burns : journal of the International Society for Burn Injuries, 2019, Volume: 45, Issue:4

    Topics: Adult; Alanine Transaminase; Alkaline Phosphatase; Anabolic Agents; Aspartate Aminotransferases; Bil

2019
Risk Factors Associated with the Development of Transaminitis in Oxandrolone-Treated Adult Burn Patients.
    Journal of burn care & research : official publication of the American Burn Association, 2019, 06-21, Volume: 40, Issue:4

    Topics: Adult; Age Factors; Anabolic Agents; Burns; Chemical and Drug Induced Liver Injury; Female; Humans;

2019
Treatment of lipodermatosclerosis with oxandrolone in a patient with stanozolol-induced hepatotoxicity.
    Journal of the American Academy of Dermatology, 2000, Volume: 43, Issue:3

    Topics: Anabolic Agents; Chemical and Drug Induced Liver Injury; Female; Humans; Hyperpigmentation; Middle A

2000
Use of oxandrolone for growth stimulation in children.
    American journal of diseases of children (1960), 1973, Volume: 126, Issue:4

    Topics: Administration, Oral; Adolescent; Age Determination by Skeleton; Age Factors; Body Height; Bone Deve

1973
Anabolic action and side effects of oxandrolone in 34 mental patients.
    Geriatrics, 1971, Volume: 26, Issue:4

    Topics: Adult; Age Factors; Aged; Arthritis; Aspartate Aminotransferases; Blood Chemical Analysis; Body Weig

1971
Androgenic and anabolic hormones.
    The Medical letter on drugs and therapeutics, 1966, May-06, Volume: 8, Issue:9

    Topics: Anabolic Agents; Androgens; Chemical and Drug Induced Liver Injury; Child; Child, Preschool; Ethyles

1966