oxamniquine has been researched along with Schistosomiasis mansoni in 121 studies
Oxamniquine: An anthelmintic with schistosomicidal activity against Schistosoma mansoni, but not against other Schistosoma spp. Oxamniquine causes worms to shift from the mesenteric veins to the liver where the male worms are retained; the female worms return to the mesentery, but can no longer release eggs. (From Martindale, The Extra Pharmacopoeia, 31st ed, p121)
oxamniquine : A racemate comprising equimolar amounts of (R)- and (S)-oxamniquine. An anthelmintic, it is administered orally for the treatment of schistomiasis caused by Schistosoma mansoni (but not by other Schistosoma species); intramuscular administration is no longer used as it causes severe pain at the injection site.
{2-[(isopropylamino)methyl]-7-nitro-1,2,3,4-tetrahydroquinolin-6-yl}methanol : A member of the class of quinolines that is 1,2,3,4-tetrahydroquinoline which is substituted at positions 2, 6, and 7 by (isopropylamino)methyl, hydroxymethyl, and nitro groups, respectively.
Schistosomiasis mansoni: Schistosomiasis caused by Schistosoma mansoni. It is endemic in Africa, the Middle East, South America, and the Caribbean and affects mainly the bowel, spleen, and liver.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To evaluate the therapeutic efficacy of oxamniquine and praziquantel, the two most clinically important schistosomicide drugs, and to compare the accuracy of faecal examination with the accuracy of oogram in testing for Schistosoma mansoni infection." | 9.10 | Efficacy of oxamniquine and praziquantel in the treatment of Schistosoma mansoni infection: a controlled trial. ( Antunes, CM; Coelho, PM; da Cunha, AS; Ferrari, ML; Tavares, CA, 2003) |
| "The activity of lovastatin associated with oxamniquine or praziquantel against schistosomiasis mansoni was evaluated in mice infected with Schistosoma mansoni." | 7.74 | Oxamniquine, praziquantel and lovastatin association in the experimental Schistosomiasis mansoni. ( Araújo, N; Coelho, PM; Katz, N; Mattos, AC; Sarvel, AK, 2008) |
| "Three patients who were treated for schistosomiasis mansoni with oxamniquine suffered generalized seizures." | 7.67 | Seizures associated with oxamniquine therapy. ( Bauer, AG; Malcolm, AD; Overbosch, D; Stokvis, H; Stuiver, PC, 1986) |
| "Human schistosomiasis is a neglected tropical disease caused by Schistosoma mansoni, S." | 5.91 | Oxamniquine derivatives overcome Praziquantel treatment limitations for Schistosomiasis. ( Alwan, SN; LoVerde, PT; McHardy, SF; Rhodes, J; Taylor, AB; Tidwell, M, 2023) |
| "Schistosomiasis is a disease of poverty affecting millions of people." | 5.56 | Multidisciplinary Preclinical Investigations on Three Oxamniquine Analogues as New Drug Candidates for Schistosomiasis*. ( Buchter, V; Gasser, G; Keiser, J; Ladaycia, A; Lepeltier, E; Mouvet, F; Ong, YC; Rothlisberger, U, 2020) |
| "Oxamniquine-treated at day 70 and measured at day 160 7." | 5.32 | On the increase of portal pressure during the acute and chronic phases of murine schistosomiasis mansoni and its reversibility after treatment with oxamniquine. ( Aguiar, BG; Coelho, PM; Costa, G; Cunha-Melo, JR, 2003) |
| "Oxamniquine treatment of infected mice inhibited such alterations." | 5.28 | Experimental schistosomiasis mansoni: electrophoretic studies on serum proteins before and after administration of oxamniquine. ( Amin, AM; Mikhail, EG, 1989) |
| "To evaluate the therapeutic efficacy of oxamniquine and praziquantel, the two most clinically important schistosomicide drugs, and to compare the accuracy of faecal examination with the accuracy of oogram in testing for Schistosoma mansoni infection." | 5.10 | Efficacy of oxamniquine and praziquantel in the treatment of Schistosoma mansoni infection: a controlled trial. ( Antunes, CM; Coelho, PM; da Cunha, AS; Ferrari, ML; Tavares, CA, 2003) |
| "Eighteen patients with acute Schistosoma mansoni infection were followed up for 2 years after treatment with praziquantel or oxamniquine." | 5.08 | Humoral immune responses in patients with acute Schistosoma mansoni infection who were followed up for two years after treatment. ( Garcia, MM; Katz, N; Pinto da Silva, RA; Rabello, AL; Rocha, RS, 1997) |
| "A comparison was made of the long-term impact of different methods of administration of chemotherapy (oxamniquine, 30 mg/kg in divided doses; or praziquantel, 40 mg/kg) on prevalence and intensity of Schistosoma mansoni infection in four areas in Kangundo Location, Machakos District, Kenya." | 5.07 | Comparison of different chemotherapy strategies against Schistosoma mansoni in Machakos District, Kenya: effects on human infection and morbidity. ( Butterworth, AE; Fulford, AJ; Kariuki, HC; Koech, D; Mbugua, GG; Ouma, JH; Sturrock, RF, 1991) |
| "A double blind trial was set up to study the pulmonary effects of specific treatment with oxamniquine of 40 patients with chronic schistosomiasis mansoni." | 5.06 | Pulmonary schistosomiasis mansoni: post-treatment pulmonary clinical-radiological alterations in patients in the chronic phase: a double-blind study. ( Ferreira, CS; Greco, DB; Lambertucci, JR; Pedroso, ER; Raso, P; Rocha, Ode C, 1987) |
| " Praziquantel and oxamniquine were effective in curing Schistosoma mansoni infection when compared to placebo." | 4.80 | Interventions for treating schistosomiasis mansoni. ( Atallah, A; Saconato, H, 2000) |
| "Oxamniquine has now been in general use for 11 years for the treatment of schistosomiasis mansoni." | 4.77 | A review of clinical experience with oxamniquine. ( Foster, R, 1987) |
| "The activity of lovastatin associated with oxamniquine or praziquantel against schistosomiasis mansoni was evaluated in mice infected with Schistosoma mansoni." | 3.74 | Oxamniquine, praziquantel and lovastatin association in the experimental Schistosomiasis mansoni. ( Araújo, N; Coelho, PM; Katz, N; Mattos, AC; Sarvel, AK, 2008) |
| "To determine the relative susceptibility of Schistosoma mansoni infections to treatment with the oxamniquine (OXA) and praziquantel (PZQ)." | 3.71 | Efficacy of oxamniquine and praziquantel in school children from two Schistosoma mansoni endemic areas. ( Mbugua, GG; Ouma, JH; Sturrock, RK; Thiong'o, FW, 2002) |
| "Schistosoma mansoni infections in mice were treated with subcurative multiple doses of either praziquantel (PZQ) or oxamniquine (OX)." | 3.69 | Drug-resistant schistosomiasis: resistance to praziquantel and oxamniquine induced in Schistosoma mansoni in mice is drug specific. ( Doenhoff, MJ; Fallon, PG, 1994) |
| "A 1% (W/V) formulation of Niclosamide (2', 5-Dichloro-4-nitrosalicylanilide) (TAP) was tested on Cebus apella monkeys as a topical prophylactic against schistosomiasis mansoni." | 3.68 | Efficacy of Niclosamide as a potential topical antipenetrant (TAP) against cercariae of Schistosoma mansoni in monkeys. ( Bruce, JI; Lightner, L; Miller, R; Yoganathan, S, 1992) |
| "This prospective study has shown that oxamniquine treatment controlled endemic schistosomiasis mansoni in a defined rural population in Castro Alves, north-east Brazil." | 3.67 | Manson's schistosomiasis in Brazil: 11-year evaluation of successful disease control with oxamniquine. ( da França Silva, JT; Hoff, R; Maguire, JH; Mott, KE; Sleigh, AC, 1986) |
| "Three patients who were treated for schistosomiasis mansoni with oxamniquine suffered generalized seizures." | 3.67 | Seizures associated with oxamniquine therapy. ( Bauer, AG; Malcolm, AD; Overbosch, D; Stokvis, H; Stuiver, PC, 1986) |
| "Mice with 64-day-old Schistosoma mansoni infection (+/- 27 worms, 8-12 pairs) were treated simultaneously with oxamniquine and hycanthone." | 3.67 | Evolution of the schistosomal hepatic lesions in mice after curative chemotherapy. ( Andrade, ZA; Grimaud, JA, 1986) |
| "praziquantel was equally effective against both parasite species." | 2.66 | The effect of metrifonate in mixed Schistosoma haematobium and Schistosoma mansoni infections in humans. ( Doehring, E; Feldmeier, H; Poggensee, U, 1986) |
| "Further research will help find the optimal dosing regimen of both these drugs in children." | 2.49 | Drugs for treating Schistosoma mansoni infection. ( Danso-Appiah, A; Donegan, S; Olliaro, PL; Sinclair, D; Utzinger, J, 2013) |
| "Human schistosomiasis is a neglected tropical disease caused by Schistosoma mansoni, S." | 1.91 | Oxamniquine derivatives overcome Praziquantel treatment limitations for Schistosomiasis. ( Alwan, SN; LoVerde, PT; McHardy, SF; Rhodes, J; Taylor, AB; Tidwell, M, 2023) |
| "Schistosomiasis is a disease of poverty affecting millions of people." | 1.56 | Multidisciplinary Preclinical Investigations on Three Oxamniquine Analogues as New Drug Candidates for Schistosomiasis*. ( Buchter, V; Gasser, G; Keiser, J; Ladaycia, A; Lepeltier, E; Mouvet, F; Ong, YC; Rothlisberger, U, 2020) |
| "OXA has been used since the 1970s to treat Schistosoma mansoni infections in the New World where S." | 1.51 | Oxamniquine resistance alleles are widespread in Old World Schistosoma mansoni and predate drug deployment. ( Al Mashikhi, KM; Al Yafae, S; Anderson, TJC; Cao, X; Chevalier, FD; Emery, AM; Garba Djirmay, A; Gouvras, AN; Guzman, MA; Hart, PJ; Holloway, SP; Idris, MA; Kinung'hi, S; Le Clec'h, W; LoVerde, PT; McDew-White, M; Menon, V; Moné, H; Mouahid, G; Rollinson, D; Taylor, AB; Webster, BL; Webster, JP, 2019) |
| "Oxamniquine is an antiparasitic agent commonly used in therapeutics against Schistosoma mansoni." | 1.34 | Design, synthesis, and in vivo evaluation of oxamniquine methacrylate and acrylamide prodrugs. ( Brandt, CA; da Silveira, MA; de Souza Menezes, CM; Filho, RP; Paula, GA; Pinto, PL, 2007) |
| "The oxamniquine treatment of acute schistosomiasis patients is followed by an improvement of a Th1 response in vitro." | 1.34 | Treatment of human acute schistosomiasis with oxamniquine induces an increase in interferon-gamma response to Schistosoma mansoni antigens. ( Abath, FG; Aroucha, ML; Barbosa, CS; Carvalho Júnior, LB; de Souza, JR; Domingues, AL; Miranda, PJ; Montenegro, SM; Morais, CN, 2007) |
| "Oxamniquine-treated at day 70 and measured at day 160 7." | 1.32 | On the increase of portal pressure during the acute and chronic phases of murine schistosomiasis mansoni and its reversibility after treatment with oxamniquine. ( Aguiar, BG; Coelho, PM; Costa, G; Cunha-Melo, JR, 2003) |
| "Schistosomiasis mansoni affects the hepatic functional reserve." | 1.31 | Surgical hepatosplenic mansonic schistosomiasis in adolescents: repercussions of the post-treatment schistosomotic burden on the hepatic functional reserve. ( Brandt, CT; Carvalheira, R; da Mota Braga, MV; Melo, KL; Pinho Sá, H, 2001) |
| "Oxamniquine derivatives were synthesized and evaluated as novel schistosomicide agents." | 1.31 | Synthesis and evaluation of new oxamniquine derivatives. ( Chiodelli, SG; da Silva, RM; da Silveira, MA; Filho, SB; Gargioni, C; Gurgel Vellosa, SA; Silva Pinto, PL, 2002) |
| "Schistosomiasis mansoni is a tropical parasitic disease caused by a blood fluke which inhabits the portal system of humans." | 1.29 | Scintigraphic findings in schistosomiasis. ( Orduña, E; Silva, F, 1995) |
| "Oxamniquine-treated worms required 4-8 days for these effects to be apparent." | 1.29 | Temporal differences in praziquantel- and oxamniquine-induced tegumental damage to adult Schistosoma mansoni: implications for drug-antibody synergy. ( Fallon, PG; Fookes, RE; Wharton, GA, 1996) |
| "Schistosomiasis mansoni has been well documented as one of the causes of infectious glomerulopathy, with mesangiocapillary glomerulonephritis being the most frequent lesion observed in this condition." | 1.28 | Schistosoma mansoni-induced mesangiocapillary glomerulonephritis: influence of therapy. ( Brito, E; Martinelli, R; Noblat, AC; Rocha, H, 1989) |
| "Praziquantel was found to be more effective, it gave 60% cure rate after the first dose, increased to 100% after the second dose, than oxamniquine which had 37% and 74% cure rates respectively." | 1.28 | Alternate chemotherapy in experimental schistosomiasis. ( Farghaly, AM; Hassan, MM; Ismail, MM; Mohamed, FE; Youssef, SM, 1992) |
| "Praziquantel was more effective in the destruction of spined papillae, wrinkling and disturbing the interpapillar spaces." | 1.28 | Scanning electron microscopy of the tegumental surface of in vivo treated Schistosoma mansoni (Saudi Arabian geographical strain) with oxamniquine and praziquantel. ( Banaja, AA; Ghandour, AM; Shalaby, IM, 1991) |
| " The reduction in adult worm recovery after dosing with 50 mg/kg oxamniquine was 89." | 1.28 | Effects of praziquantel and oxamniquine on a Saudi Arabian strain of Schistosoma mansoni in mice. ( Banaja, AA; Ghandour, AM; Shalaby, IM, 1990) |
| "Oxamniquine treatment of infected mice inhibited such alterations." | 1.28 | Experimental schistosomiasis mansoni: electrophoretic studies on serum proteins before and after administration of oxamniquine. ( Amin, AM; Mikhail, EG, 1989) |
| "Treatment with oxamniquine resulted in near total eradication of S." | 1.28 | Evaluation of hepatic fibrosis after oxamniquine therapy of murine schistosomiasis. ( Girgis, NI; Ishak, EA; Khayyal, MT; Mansour, MM; Morcos, SH; Saleh, S, 1992) |
| " There were no significant differences in oxamniquine mean area under the plasma concentration time curve (AUC), plasma half life (T1/2), or time to reach peak concentration (Tmax)." | 1.27 | Oxamniquine pharmacokinetics in hepatosplenic schistosomiasis in the Sudan. ( Daneshmend, TK; Homeida, MA, 1987) |
| "Oxamniquine was equally effective in children receiving it in both 1981 and 1983, and the efficacy of praziquantel resembled that of oxamniquine." | 1.27 | Immunity after treatment of human schistosomiasis mansoni. III. Long-term effects of treatment and retreatment. ( arap Siongok, TK; Bensted-Smith, R; Butterworth, AE; Dalton, PR; Kariuki, HC; Koech, D; Mugambi, M; Ouma, JH; Sturrock, RF, 1987) |
| " Isolates from infected children were passaged into mice and dosed with oxamniquine." | 1.27 | Tolerance of Kenyan Schistosoma mansoni to oxamniquine. ( Bruce, JI; Coles, GC; Katz, N; Kinoti, GK; Mutahi, WT, 1987) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 45 (37.19) | 18.7374 |
| 1990's | 35 (28.93) | 18.2507 |
| 2000's | 30 (24.79) | 29.6817 |
| 2010's | 9 (7.44) | 24.3611 |
| 2020's | 2 (1.65) | 2.80 |
| Authors | Studies |
|---|---|
| Filho, RP | 1 |
| de Souza Menezes, CM | 1 |
| Pinto, PL | 1 |
| Paula, GA | 1 |
| Brandt, CA | 1 |
| da Silveira, MA | 2 |
| Alwan, SN | 1 |
| Taylor, AB | 2 |
| Rhodes, J | 1 |
| Tidwell, M | 1 |
| McHardy, SF | 1 |
| LoVerde, PT | 3 |
| Chevalier, FD | 2 |
| Le Clec'h, W | 1 |
| McDew-White, M | 1 |
| Menon, V | 1 |
| Guzman, MA | 1 |
| Holloway, SP | 1 |
| Cao, X | 1 |
| Kinung'hi, S | 1 |
| Gouvras, AN | 1 |
| Webster, BL | 1 |
| Webster, JP | 1 |
| Emery, AM | 1 |
| Rollinson, D | 1 |
| Garba Djirmay, A | 1 |
| Al Mashikhi, KM | 1 |
| Al Yafae, S | 1 |
| Idris, MA | 1 |
| Moné, H | 1 |
| Mouahid, G | 1 |
| Hart, PJ | 1 |
| Anderson, TJC | 1 |
| Buchter, V | 1 |
| Ong, YC | 1 |
| Mouvet, F | 1 |
| Ladaycia, A | 1 |
| Lepeltier, E | 1 |
| Rothlisberger, U | 1 |
| Keiser, J | 2 |
| Gasser, G | 2 |
| Hess, J | 1 |
| Panic, G | 1 |
| Patra, M | 1 |
| Mastrobuoni, L | 1 |
| Spingler, B | 1 |
| Roy, S | 1 |
| Frahm, S | 1 |
| Anisuzzaman, A | 1 |
| Prodjinotho, UF | 1 |
| Vejzagić, N | 1 |
| Verschoor, A | 1 |
| Prazeres da Costa, C | 1 |
| Danso-Appiah, A | 1 |
| Olliaro, PL | 1 |
| Donegan, S | 1 |
| Sinclair, D | 1 |
| Utzinger, J | 1 |
| Vimieiro, AC | 1 |
| Araújo, N | 3 |
| Katz, N | 9 |
| Kusel, JR | 2 |
| Coelho, PM | 12 |
| Valentim, CL | 1 |
| Anderson, TJ | 1 |
| Sabino, KR | 1 |
| Nunes, MB | 1 |
| Petroianu, A | 1 |
| Mattos, AC | 3 |
| Sarvel, AK | 1 |
| Faria-Pinto, Pd | 1 |
| Montesano, MA | 1 |
| Jacinto, AA | 1 |
| Santos, RS | 1 |
| Bordin, FH | 1 |
| Ferreira, AP | 1 |
| Penido, ML | 1 |
| Vasconcelos, EG | 1 |
| Coura, JR | 1 |
| Conceição, MJ | 2 |
| Mduluza, T | 2 |
| Mutapi, F | 2 |
| Ruwona, T | 1 |
| Kaluka, D | 1 |
| Midzi, N | 1 |
| Ndhlovu, PD | 2 |
| Borges-Pereira, J | 1 |
| Peregrino, AJ | 1 |
| Puglia, PM | 1 |
| Nobrega, JP | 1 |
| Livramento, JA | 1 |
| Marques-Dias, MJ | 2 |
| Scaff, M | 1 |
| Coles, GC | 3 |
| Thiong'o, FW | 1 |
| Mbugua, GG | 2 |
| Ouma, JH | 4 |
| Sturrock, RK | 1 |
| Gomes, YM | 1 |
| Pereira, VR | 1 |
| Nakazawa, M | 1 |
| Montarroyos, U | 1 |
| Souza, WV | 1 |
| Abath, FG | 2 |
| Teles, HM | 1 |
| de Carvalho, ME | 1 |
| Santos Ferreira, C | 1 |
| Zacharias, F | 1 |
| de Lima, VR | 1 |
| Fadel, ML | 1 |
| Ferrari, ML | 1 |
| Antunes, CM | 1 |
| Tavares, CA | 2 |
| da Cunha, AS | 1 |
| Hagan, P | 2 |
| Woolhouse, ME | 1 |
| Lopes, RI | 2 |
| Lopes, RN | 2 |
| Leite, KR | 2 |
| Prando, D | 2 |
| Enk, MJ | 2 |
| Amorim, A | 1 |
| Schall, VT | 1 |
| Costa, G | 1 |
| Aguiar, BG | 1 |
| Cunha-Melo, JR | 1 |
| Carvalho, MG | 1 |
| Mello, RT | 3 |
| Soares, AL | 1 |
| Bicalho, RS | 1 |
| Lima e Silva, FC | 2 |
| García, N | 1 |
| Isturiz, G | 1 |
| Aular, S | 1 |
| Incani, RN | 2 |
| Araújo, KC | 1 |
| Rosa e Silva, Cd | 1 |
| Barbosa, CS | 3 |
| Ferrari, TC | 1 |
| Andrade, ZA | 3 |
| Baptista, AP | 1 |
| Santana, TS | 1 |
| de Souza, JR | 1 |
| Morais, CN | 1 |
| Aroucha, ML | 1 |
| Miranda, PJ | 1 |
| Domingues, AL | 2 |
| Carvalho Júnior, LB | 1 |
| Montenegro, SM | 1 |
| Pereira, GC | 1 |
| Jannotti-Passos, LK | 1 |
| Zech Coelho, PM | 1 |
| Fallon, PG | 5 |
| Hamilton, JV | 1 |
| Doenhoff, MJ | 5 |
| Rebello, LH | 1 |
| Da Silva, JR | 1 |
| Gutfilen, B | 1 |
| Bernardo-Filho, M | 1 |
| de Jesus, AM | 1 |
| Almeida, RP | 1 |
| Bacellar, O | 1 |
| Araujo, MI | 1 |
| Demeure, C | 2 |
| Bina, JC | 3 |
| Dessein, AJ | 3 |
| Carvalho, EM | 1 |
| de Lima e Costa, MF | 1 |
| Rocha, RS | 3 |
| Coura Filho, P | 2 |
| Fookes, RE | 2 |
| Wharton, GA | 1 |
| Ahmed, SA | 1 |
| Gad, MZ | 1 |
| Cook, J | 1 |
| Reich, MR | 1 |
| Nishioka, Sde A | 1 |
| Orduña, E | 1 |
| Silva, F | 1 |
| Birrie, H | 1 |
| Abebe, F | 1 |
| Ayele, T | 2 |
| Toppa, NH | 1 |
| Feldmann, JS | 1 |
| Gonçalves, R | 1 |
| Rabello, AL | 1 |
| Garcia, MM | 1 |
| Pinto da Silva, RA | 1 |
| Mubarak, JS | 1 |
| Niang, M | 2 |
| Butterworth, AE | 4 |
| Sturrock, RF | 3 |
| Stelma, FF | 1 |
| Sall, S | 1 |
| Daff, B | 1 |
| Sow, S | 1 |
| Gryseels, B | 3 |
| Webster, M | 1 |
| Fulford, AJ | 3 |
| Kimani, G | 1 |
| Dunne, DW | 2 |
| Assis, AM | 1 |
| Barreto, ML | 1 |
| Prado, MS | 1 |
| Reis, MG | 1 |
| Parraga, IM | 1 |
| Blanton, RE | 1 |
| Ribeiro, F | 1 |
| Nogueira-Machado, JA | 1 |
| Kusel, J | 1 |
| Caldas, IR | 1 |
| Correa-Oliveira, R | 1 |
| Colosimo, E | 1 |
| Carvalho, OS | 1 |
| Massara, CL | 1 |
| Colley, DG | 1 |
| Gazzinelli, G | 1 |
| Saconato, H | 1 |
| Atallah, A | 1 |
| Brandt, CT | 1 |
| da Mota Braga, MV | 1 |
| Melo, KL | 1 |
| Pinho Sá, H | 1 |
| Carvalheira, R | 1 |
| Beck, L | 1 |
| Favre, TC | 1 |
| Pieri, OS | 1 |
| Zani, LC | 1 |
| Domas, GG | 1 |
| Filho, SB | 1 |
| Gargioni, C | 1 |
| Silva Pinto, PL | 1 |
| Chiodelli, SG | 1 |
| Gurgel Vellosa, SA | 1 |
| da Silva, RM | 1 |
| Bonesso-Sabadini, PI | 1 |
| de Souza Dias, LC | 1 |
| Paz, JA | 1 |
| Valente, M | 1 |
| Casella, EB | 1 |
| Morcos, SH | 1 |
| Mansour, MM | 1 |
| Khayyal, MT | 1 |
| Saleh, S | 1 |
| Ishak, EA | 1 |
| Girgis, NI | 2 |
| Bruce, JI | 3 |
| Miller, R | 1 |
| Lightner, L | 1 |
| Yoganathan, S | 1 |
| Kano, PH | 1 |
| Delgado, VS | 1 |
| Suárez, DP | 1 |
| Cesari, IM | 1 |
| Cioli, D | 1 |
| Pica-Mattoccia, L | 1 |
| Moroni, R | 1 |
| Ismail, MM | 1 |
| Farghaly, AM | 1 |
| Hassan, MM | 2 |
| Youssef, SM | 1 |
| Mohamed, FE | 1 |
| Shalaby, IM | 2 |
| Banaja, AA | 2 |
| Ghandour, AM | 2 |
| Kariuki, HC | 2 |
| Koech, D | 2 |
| de Souza, CP | 1 |
| Kinoti, GK | 2 |
| Andrade Filho, Ade S | 1 |
| de Queiroz, AC | 1 |
| Rihet, P | 1 |
| Demeure, CE | 1 |
| Bourgois, A | 1 |
| Prata, A | 2 |
| de Jonge, N | 1 |
| Schommer, G | 1 |
| Feldmeier, H | 2 |
| Krijger, FW | 1 |
| Dafalla, AA | 1 |
| Bienzle, U | 1 |
| Deelder, AM | 2 |
| Marsden, PD | 1 |
| Amin, AM | 3 |
| Mikhail, EG | 3 |
| el-Hawey, AM | 1 |
| Wahib, AA | 1 |
| Ossman, OM | 1 |
| el Zahaby, AA | 1 |
| Martinelli, R | 2 |
| Noblat, AC | 1 |
| Brito, E | 1 |
| Rocha, H | 2 |
| Lambertucci, JR | 3 |
| Sleigh, AC | 1 |
| Hoff, R | 1 |
| Mott, KE | 1 |
| Maguire, JH | 1 |
| da França Silva, JT | 1 |
| Greco, DB | 2 |
| Pedroso, ER | 2 |
| Rocha, MO | 1 |
| Raso, P | 2 |
| Ferreira, CS | 2 |
| Davidson, BL | 1 |
| el-Kassimi, F | 1 |
| Uz-Zaman, A | 1 |
| Pillai, DK | 1 |
| Doehring, E | 1 |
| Poggensee, U | 1 |
| Stokvis, H | 1 |
| Bauer, AG | 1 |
| Stuiver, PC | 1 |
| Malcolm, AD | 1 |
| Overbosch, D | 1 |
| Sabah, AA | 2 |
| Fletcher, C | 2 |
| Webbe, G | 2 |
| Grimaud, JA | 1 |
| el-Masry, NA | 1 |
| Farid, Z | 1 |
| Bassily, S | 1 |
| Kilpatrick, ME | 1 |
| Watten, RH | 1 |
| Polderman, AM | 2 |
| Bahakim, HH | 1 |
| Hussain, S | 1 |
| Al Sulaimani, SH | 1 |
| Daneshmend, TK | 1 |
| Homeida, MA | 1 |
| Creasey, AM | 1 |
| Taylor, P | 1 |
| Thomas, JE | 1 |
| Pereira, LJ | 1 |
| Bensted-Smith, R | 1 |
| Dalton, PR | 1 |
| Mugambi, M | 1 |
| arap Siongok, TK | 1 |
| Kloetzel, K | 2 |
| Schuster, NH | 1 |
| Foster, R | 1 |
| Nkulikyinka, L | 1 |
| Coosemans, MH | 1 |
| Begley, M | 1 |
| Caillol, D | 1 |
| Fueri, J | 1 |
| dos Reis, MG | 1 |
| Rocha, Ode C | 1 |
| Mutahi, WT | 2 |
| Abdel Rahim, IM | 1 |
| Haridi, AA | 2 |
| Abdel-Hameed, AA | 2 |
| De Caluwe, P | 1 |
| Taddese, K | 1 |
| Zein, ZA | 1 |
| Yeang, F | 1 |
| Nascimento, BC | 1 |
| Chamone, M | 1 |
| Sobh, MA | 1 |
| Moustafa, FE | 1 |
| Sally, SM | 1 |
| Ghoniem, MA | 1 |
| Abdel-Rahim, IM | 1 |
| de Azevedo Vergetti, AM | 1 |
| Alvim, Ade C | 1 |
| Coutinho, A | 1 |
| Kohn, A | 1 |
| Bruce, J | 1 |
| Kinoti, G | 1 |
| Coles, G | 1 |
| Madwar, MA | 1 |
| Strickland, GT | 1 |
| Melo, JE | 1 |
| Lima, BB | 1 |
| Hillyer, GV | 1 |
| Vazquez, G | 1 |
| Okela, GB | 1 |
| da Silva, LC | 1 |
| Alves, VA | 1 |
| Abrantes, CP | 1 |
| Lima, DM | 1 |
| Christo, CH | 1 |
| De Brito, T | 1 |
| Al-Aska, AK | 1 |
5 reviews available for oxamniquine and Schistosomiasis mansoni
| Article | Year |
|---|---|
Drugs for treating Schistosoma mansoni infection.
Topics: Adolescent; Adult; Child; Commiphora; Humans; Oxamniquine; Plant Extracts; Praziquantel; Randomized | 2013 |
Interventions for treating schistosomiasis mansoni.
Topics: Humans; Oxamniquine; Praziquantel; Schistosomiasis mansoni; Schistosomicides | 2000 |
Spinal cord schistosomiasis in children: analysis of seven cases.
Topics: Adolescent; Anthelmintics; Anti-Inflammatory Agents; Child; Child, Preschool; Female; Humans; Magnet | 2002 |
[Specific treatment as a weapon for controlling schistosomiasis].
Topics: Adolescent; Brazil; Child; Child, Preschool; Clinical Trials as Topic; Female; Follow-Up Studies; He | 1992 |
A review of clinical experience with oxamniquine.
Topics: Central Nervous System Diseases; Humans; Nitroquinolines; Oxamniquine; Schistosomiasis mansoni | 1987 |
16 trials available for oxamniquine and Schistosomiasis mansoni
| Article | Year |
|---|---|
Efficacy of oxamniquine and praziquantel in the treatment of Schistosoma mansoni infection: a controlled trial.
Topics: Adult; Animals; Brazil; Feces; Female; Humans; Male; Oxamniquine; Parasite Egg Count; Placebos; Praz | 2003 |
Chemotherapy-induced, age-related changes in antischistosome antibody responses.
Topics: Adolescent; Age Factors; Animals; Antibodies, Helminth; Antiplatyhelmintic Agents; Child; Endemic Di | 2003 |
Humoral immune responses in patients with acute Schistosoma mansoni infection who were followed up for two years after treatment.
Topics: Abdomen; Adolescent; Adult; Age Factors; Animals; Antibodies, Helminth; Antiplatyhelmintic Agents; C | 1997 |
Oxamniquine cures Schistosoma mansoni infection in a focus in which cure rates with praziquantel are unusually low.
Topics: Adolescent; Adult; Aged; Child; Child, Preschool; Female; Humans; Male; Middle Aged; Oxamniquine; Pr | 1997 |
Schistosoma mansoni infection and nutritional status in schoolchildren: a randomized, double-blind trial in northeastern Brazil.
Topics: Adolescent; Anthropometry; Body Mass Index; Body Weight; Brazil; Child; Double-Blind Method; Female; | 1998 |
Comparison of different chemotherapy strategies against Schistosoma mansoni in Machakos District, Kenya: effects on human infection and morbidity.
Topics: Adolescent; Age Factors; Child; Cohort Studies; Feces; Follow-Up Studies; Hepatomegaly; Humans; Keny | 1991 |
Mixed Schistosoma haematobium and S. mansoni infection: effect of different treatments on the serum level of circulating anodic antigen (CAA).
Topics: Animals; Antigens, Helminth; Child; Enzyme-Linked Immunosorbent Assay; Feces; Humans; Male; Oxamniqu | 1990 |
The effect of metrifonate in mixed Schistosoma haematobium and Schistosoma mansoni infections in humans.
Topics: Adolescent; Child; Clinical Trials as Topic; Feces; Humans; Lung; Male; Oxamniquine; Parasite Egg Co | 1986 |
Preliminary clinical trial of oral oxamniquine in the treatment of Schistosoma mansoni in children in Ethiopia.
Topics: Administration, Oral; Child; Double-Blind Method; Ethiopia; Humans; Nitroquinolines; Oxamniquine; Ra | 1986 |
Dosage trial of a combination of oxamniquine and praziquantel in the treatment of schistosomiasis in Zimbabwean schoolchildren.
Topics: Adolescent; Child; Clinical Trials as Topic; Drug Synergism; Drug Therapy, Combination; Female; Huma | 1986 |
Field trials of praziquantel and oxamniquine for the treatment of schistosomiasis mansoni in Burundi.
Topics: Adult; Burundi; Clinical Trials as Topic; Feces; Humans; Nitroquinolines; Oxamniquine; Parasite Egg | 1987 |
Pulmonary schistosomiasis mansoni: post-treatment pulmonary clinical-radiological alterations in patients in the chronic phase: a double-blind study.
Topics: Adolescent; Child; Clinical Trials as Topic; Double-Blind Method; Humans; Lung; Nitroquinolines; Oxa | 1987 |
Field study of different oxamniquine dose for Schistosoma mansoni in Gezira, Sudan.
Topics: Adolescent; Adult; Child; Child, Preschool; Costs and Cost Analysis; Dose-Response Relationship, Dru | 1988 |
Cure rates and egg reduction in treatment of intestinal schistosomiasis with oxamniquine and praziquantel in Maniema, Zaire.
Topics: Adolescent; Adult; Child; Democratic Republic of the Congo; Feces; Humans; Nitroquinolines; Oxamniqu | 1988 |
Comparison between the efficacy of oxamniquine and praziquantel in the treatment of Schistosoma mansoni infections on a sugar estate in Ethiopia.
Topics: Adolescent; Adult; Drug Administration Schedule; Drug Evaluation; Drug Tolerance; Ethiopia; Female; | 1988 |
A field evaluation of three dose levels of oxamniquine in Gezira--Sudan.
Topics: Adolescent; Child; Child, Preschool; Clinical Trials as Topic; Humans; Nitroquinolines; Oxamniquine; | 1988 |
100 other studies available for oxamniquine and Schistosomiasis mansoni
| Article | Year |
|---|---|
Design, synthesis, and in vivo evaluation of oxamniquine methacrylate and acrylamide prodrugs.
Topics: Acrylamide; Animals; Drug Design; Drug Evaluation, Preclinical; Male; Mesenteric Veins; Methacrylate | 2007 |
Oxamniquine derivatives overcome Praziquantel treatment limitations for Schistosomiasis.
Topics: Animals; Anthelmintics; Combined Modality Therapy; Humans; Neglected Diseases; Oxamniquine; Praziqua | 2023 |
Oxamniquine resistance alleles are widespread in Old World Schistosoma mansoni and predate drug deployment.
Topics: Adaptation, Physiological; Alleles; Animals; Cricetinae; Drug Resistance; Humans; Niger; Oman; Oxamn | 2019 |
Multidisciplinary Preclinical Investigations on Three Oxamniquine Analogues as New Drug Candidates for Schistosomiasis*.
Topics: Animals; Humans; Oxamniquine; Pharmaceutical Preparations; Schistosoma mansoni; Schistosomiasis; Sch | 2020 |
Ferrocenyl, Ruthenocenyl, and Benzyl Oxamniquine Derivatives with Cross-Species Activity against Schistosoma mansoni and Schistosoma haematobium.
Topics: Animals; Anthelmintics; Chemistry, Pharmaceutical; Disease Models, Animal; Female; Male; Mice; Organ | 2017 |
A novel cell-free method to culture Schistosoma mansoni from cercariae to juvenile worm stages for in vitro drug testing.
Topics: Animals; Artemether; Cercaria; Culture Media, Serum-Free; Drug Evaluation, Preclinical; Humans; Mefl | 2019 |
Schistogram changes after administration of antischistosomal drugs in mice at the early phase of Schistosoma mansoni infection.
Topics: Animals; Artemisinins; Artesunate; Drug Therapy, Combination; Female; Mice; Oxamniquine; Parasite Eg | 2013 |
Efficient linkage mapping using exome capture and extreme QTL in schistosome parasites.
Topics: Animals; Chromosome Mapping; Cricetinae; Crosses, Genetic; Exome; Female; Gene Frequency; Genetic Li | 2014 |
Ectopic Schistosoma mansoni Eggs Inside a Lipoma.
Topics: Adult; Animals; Humans; Lipoma; Male; Ovum; Oxamniquine; Schistosoma mansoni; Schistosomiasis manson | 2016 |
Oxamniquine, praziquantel and lovastatin association in the experimental Schistosomiasis mansoni.
Topics: Animals; Drug Therapy, Combination; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lovastatin; Mice | 2008 |
Association of oxamniquine praziquantel and clonazepam in experimental Schistosomiasis mansoni.
Topics: Animals; Clonazepam; Drug Evaluation, Preclinical; Drug Therapy, Combination; Female; Liver; Male; M | 2008 |
Antibody reactivity against potato apyrase, a protein that shares epitopes with Schistosoma mansoni ATP diphosphohydrolase isoforms, in acute and chronically infected mice, after chemotherapy and reinfection.
Topics: Acute Disease; Animals; Anthelmintics; Antibodies, Helminth; Antigens, Helminth; Apyrase; Chronic Di | 2010 |
Specific schistosomiasis treatment as a strategy for disease control.
Topics: Brazil; Cohort Studies; Female; Humans; Oxamniquine; Parasite Egg Count; Pregnancy; Prevalence; Schi | 2010 |
Similar cellular responses after treatment with either praziquantel or oxamniquine in Schistosoma mansoni infection.
Topics: Adolescent; Animals; Antigens, Helminth; Child; Cohort Studies; Cytokines; Enzyme-Linked Immunosorbe | 2009 |
Influence of specific treatment on the morbidity of Schistosomiasis mansoni in an endemic area of Minas Gerais, Brazil.
Topics: Animals; Brazil; Endemic Diseases; Follow-Up Studies; Humans; Oxamniquine; Prevalence; Schistosomias | 2002 |
[Schistosomiasis of the spinal cord: analysis of 80 cases].
Topics: Adolescent; Adult; Aged; Anti-Inflammatory Agents; Brazil; Child; Child, Preschool; Dexamethasone; F | 2002 |
Drug resistance or tolerance in schistosomes?
Topics: Animals; Anthelmintics; Drug Resistance; Humans; Oxamniquine; Praziquantel; Schistosoma mansoni; Sch | 2002 |
Efficacy of oxamniquine and praziquantel in school children from two Schistosoma mansoni endemic areas.
Topics: Adolescent; Animals; Child; Child, Preschool; Cross-Sectional Studies; Endemic Diseases; Humans; Log | 2002 |
Antibody isotype responses to egg antigens in human chronic Schistosomiasis mansoni before and after treatment.
Topics: Animals; Antibodies, Helminth; Antigens, Helminth; Brazil; Enzyme-Linked Immunosorbent Assay; Feces; | 2002 |
Schistosomiasis mansoni in Bananal (State of São Paulo, Brazil): I. Efficiency of diagnostic and treatment procedures.
Topics: Adolescent; Adult; Animals; Brazil; Child; Child, Preschool; Feces; Female; Humans; Infant; Infant, | 2002 |
Testicular schistosomiasis simulating malignancy.
Topics: Adult; Humans; Male; Oxamniquine; Schistosomiasis mansoni; Schistosomicides; Testicular Diseases | 2003 |
Acute schistosomiasis outbreak in the metropolitan area of Belo Horizonte, Minas Gerais: alert about the risk of unnoticed transmission increased by growing rural tourism.
Topics: Acute Disease; Animals; Biomphalaria; Brazil; Disease Outbreaks; Feces; Female; Health Knowledge, At | 2003 |
On the increase of portal pressure during the acute and chronic phases of murine schistosomiasis mansoni and its reversibility after treatment with oxamniquine.
Topics: Animals; Hypertension, Portal; Male; Mice; Oxamniquine; Schistosomiasis mansoni; Schistosomicides | 2003 |
Murine schistosomiasis mansoni: process of blood coagulation at pre-patent, acute and chronic phases, and consequence of chemotherapeutic cure on the reversion of changes.
Topics: Acute Disease; Animals; Blood Coagulation; Blood Coagulation Factors; Chronic Disease; Female; Mice; | 2005 |
The efficacy of human schistosomicide treatment may depend on the rate of transmission.
Topics: Animals; Antibodies, Helminth; Fluorescent Antibody Technique, Indirect; Humans; Immunoglobulin M; O | 2006 |
Clinical-epidemiological profile of children with schistosomal myeloradiculopathy attended at the Instituto Materno-Infantil de Pernambuco.
Topics: Adolescent; Anthelmintics; Child; Child, Preschool; Female; Humans; Male; Neuroschistosomiasis; Oxam | 2006 |
Remodeling of hepatic vascular changes after specific chemotherapy of schistosomal periportal fibrosis.
Topics: Animals; Anthelmintics; Chronic Disease; Disease Models, Animal; Female; Granuloma; Humans; Liver Ci | 2006 |
Treatment of human acute schistosomiasis with oxamniquine induces an increase in interferon-gamma response to Schistosoma mansoni antigens.
Topics: Acute Disease; Adolescent; Adult; Animals; Antibodies, Helminth; Antigens, Helminth; Child; Disease | 2007 |
Evaluation of the effect of oxamniquine, praziquantel and a combination of both drugs on the intramolluscan phase of Schistosoma mansoni.
Topics: Animals; Anthelmintics; Biomphalaria; Drug Therapy, Combination; Oxamniquine; Praziquantel; Schistos | 2007 |
Testicular schistosomiasis caused by Schistosoma mansoni: a case report from Brazil.
Topics: Adult; Humans; Magnetic Resonance Imaging; Male; Orchiectomy; Oxamniquine; Schistosomiasis mansoni; | 2007 |
A case of Schistosoma mansoni infection treated during the prepatent period.
Topics: Administration, Oral; Adult; Animals; Dose-Response Relationship, Drug; Feces; Female; Follow-Up Stu | 2008 |
Efficacy of treatment of murine Schistosoma mansoni infections with praziquantel and oxamniquine correlates with infection intensity: role of host antibody.
Topics: Animals; Antibodies, Helminth; Antigens, Protozoan; Female; Male; Mice; Oxamniquine; Praziquantel; S | 1995 |
Oxamniquine: a labeling procedure with technetium-99m and a biodistribution study in mice.
Topics: Animals; Isotope Labeling; Mice; Mice, Inbred Strains; Organotechnetium Compounds; Oxamniquine; Radi | 1994 |
Drug-resistant schistosomiasis: resistance to praziquantel and oxamniquine induced in Schistosoma mansoni in mice is drug specific.
Topics: Animals; Drug Resistance; Female; Male; Mice; Oxamniquine; Praziquantel; Schistosoma mansoni; Schist | 1994 |
Correlation between cell-mediated immunity and degree of infection in subjects living in an endemic area of schistosomiasis.
Topics: Adolescent; Adult; Antigens, Helminth; Child; Child, Preschool; Female; Humans; Immunity, Cellular; | 1993 |
A 13-year follow-up of treatment and snail control in an area endemic for Schistosoma mansoni in Brazil: incidence of infection and reinfection.
Topics: Adolescent; Adult; Age Factors; Animals; Biomphalaria; Brazil; Child; Child, Preschool; Cohort Studi | 1993 |
Temporal differences in praziquantel- and oxamniquine-induced tegumental damage to adult Schistosoma mansoni: implications for drug-antibody synergy.
Topics: Animals; Antibodies, Helminth; Antigens, Helminth; Blotting, Western; Drug Synergism; Enzyme-Linked | 1996 |
Effect of schistosomal infection and its treatment on some key enzymes of glucose metabolism in mice livers.
Topics: Animals; Body Weight; Citric Acid Cycle; Female; Glucose; Glycolysis; Liver; Liver Glycogen; Male; M | 1995 |
Case 4-1996: paralysis due to schistosomiasis.
Topics: Drug Resistance; Humans; Oxamniquine; Praziquantel; Schistosomiasis mansoni; Schistosomicides | 1996 |
Case 4-1996: paralysis due to schistosomiasis.
Topics: Humans; Oxamniquine; Praziquantel; Schistosomiasis mansoni; Schistosomicides; Spinal Cord Diseases | 1996 |
Scintigraphic findings in schistosomiasis.
Topics: Acute Disease; Adolescent; Child; Follow-Up Studies; Hepatomegaly; Humans; Liver Function Tests; Mal | 1995 |
The efficacy of oxamniquine in selective population chemotherapy in Ethiopia.
Topics: Adolescent; Adult; Child; Child, Preschool; Ethiopia; Female; Humans; Infant; Infant, Newborn; Male; | 1995 |
Schistosoma mansoni: permanence of modulation of the granulomatous inflammatory response in mice cured in the chronic phase.
Topics: Animals; Granuloma; Inflammation; Liver Diseases, Parasitic; Mice; Oxamniquine; Schistosomiasis mans | 1996 |
Schistosoma mansoni: maturation rate and drug susceptibility of different geographic isolates.
Topics: Animals; Digestive System; Drug Resistance; Feces; Female; Fertility; Kenya; Liver; Male; Mice; Oxam | 1997 |
Effect of praziquantel and oxamniquine treatment on human isotype responses to Schistosoma mansoni: elevated IgE to adult worm.
Topics: Animals; Antibodies, Helminth; Antigens, Helminth; Drug Therapy, Combination; Female; Humans; Immuno | 1997 |
Activity of oxamniquine at skin, pulmonary and sexual maturation phases, on a Schistosoma mansoni strain (R1) previously reported as resistant at the adult phase.
Topics: Animals; Drug Resistance; Female; Life Cycle Stages; Male; Mice; Oxamniquine; Schistosoma mansoni; S | 1998 |
Praziquantel--its use, cost and possible development of resistance.
Topics: Africa; Animals; Anthelmintics; Child; Drug Resistance; Female; Humans; Oxamniquine; Praziquantel; P | 1999 |
Susceptibility and resistance to Schistosoma mansoni reinfection: parallel cellular and isotypic immunologic assessment.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Animals; Antibodies, Helminth; Antigens, Helminth; Antim | 2000 |
Surgical hepatosplenic mansonic schistosomiasis in adolescents: repercussions of the post-treatment schistosomotic burden on the hepatic functional reserve.
Topics: Adolescent; Animals; Child; Esophageal and Gastric Varices; Follow-Up Studies; Gastrointestinal Hemo | 2001 |
Replacing oxamniquine by praziquantel against Schistosoma mansoni infection in a rural community from the sugar-cane zone of Northeast Brazil: an epidemiological follow-up.
Topics: Animals; Anthelmintics; Brazil; Crops, Agricultural; Follow-Up Studies; Humans; Oxamniquine; Parasit | 2001 |
Synthesis and evaluation of new oxamniquine derivatives.
Topics: Animals; Drug Evaluation, Preclinical; Male; Mice; Oxamniquine; Schistosomiasis mansoni; Schistosomi | 2002 |
Altered response of strain of Schistosoma mansoni to oxamniquine and praziquantel.
Topics: Animals; Drug Resistance; Female; Humans; Mice; Oxamniquine; Praziquantel; Schistosoma mansoni; Schi | 2002 |
Evaluation of hepatic fibrosis after oxamniquine therapy of murine schistosomiasis.
Topics: Animals; Hydroxyproline; Liver; Liver Cirrhosis; Male; Mice; Oxamniquine; Parasite Egg Count; Schist | 1992 |
Efficacy of Niclosamide as a potential topical antipenetrant (TAP) against cercariae of Schistosoma mansoni in monkeys.
Topics: Administration, Topical; Animals; Cebus; Drug Resistance; Female; Larva; Male; Niclosamide; Oxamniqu | 1992 |
[Measures for control of schistosomiasis adopted by the National Health Foundation].
Topics: Adult; Animals; Brazil; Child; Disease Vectors; Foundations; Humans; Molluscacides; National Health | 1992 |
Experimental chemotherapy of Schistosoma mansoni with praziquantel and oxamniquine: differential effect of single or combined formulations of drugs on various strains and on both sexes of the parasite.
Topics: Animals; Dose-Response Relationship, Drug; Drug Combinations; Female; Intestines; Liver; Male; Mice; | 1992 |
Schistosoma mansoni: hycanthone/oxamniquine resistance is controlled by a single autosomal recessive gene.
Topics: Animals; Crosses, Genetic; Drug Resistance; Female; Fertility; Genes, Helminth; Genes, Recessive; Hy | 1992 |
Alternate chemotherapy in experimental schistosomiasis.
Topics: Animals; Drug Therapy, Combination; Feces; Mice; Oxamniquine; Parasite Egg Count; Praziquantel; Schi | 1992 |
Scanning electron microscopy of the tegumental surface of in vivo treated Schistosoma mansoni (Saudi Arabian geographical strain) with oxamniquine and praziquantel.
Topics: Animals; Mice; Microscopy, Electron, Scanning; Oxamniquine; Praziquantel; Schistosoma mansoni; Schis | 1991 |
ELISA detection of specific circulating antibodies against Schistosoma mansoni in mice after treatment with oxamniquine.
Topics: Administration, Oral; Animals; Antibodies, Helminth; Antigen-Antibody Reactions; Antigens, Helminth; | 1991 |
Efficacy of alternating therapy with oxamniquine and praziquantel to treat Schistosoma mansoni in children following failure of first treatment.
Topics: Adolescent; Animals; Child; Drug Therapy, Combination; Feces; Humans; Male; Mice; Oxamniquine; Paras | 1991 |
[Schistosomal meningoradiculitis: clinico-laboratory study of 3 treated cases].
Topics: Adrenal Cortex Hormones; Adult; Humans; Male; Middle Aged; Myelitis; Oxamniquine; Radiculopathy; Sch | 1991 |
Evidence for an association between human resistance to Schistosoma mansoni and high anti-larval IgE levels.
Topics: Adolescent; Adult; Allergens; Animals; Antibodies, Helminth; Antigens, Helminth; Antigens, Surface; | 1991 |
Fertile flukes and mediating molluscs.
Topics: Animals; Biomphalaria; Brazil; Child; Disease Vectors; Humans; Oxamniquine; Schistosomiasis mansoni | 1990 |
Effects of praziquantel and oxamniquine on a Saudi Arabian strain of Schistosoma mansoni in mice.
Topics: Administration, Oral; Animals; Dose-Response Relationship, Drug; Mice; Nitroquinolines; Oxamniquine; | 1990 |
Experimental schistosomiasis mansoni: electrophoretic studies on serum proteins before and after administration of oxamniquine.
Topics: Animals; Blood Protein Electrophoresis; Blood Proteins; Male; Mice; Nitroquinolines; Oxamniquine; Sc | 1989 |
Ultrasonographic profile of the liver and caliber of portal vein after oral antibilharzial drugs.
Topics: Adult; Humans; Liver; Male; Nitroquinolines; Oxamniquine; Portal Vein; Praziquantel; Schistosomiasis | 1989 |
Schistosoma mansoni-induced mesangiocapillary glomerulonephritis: influence of therapy.
Topics: Adult; Antihypertensive Agents; Cyclophosphamide; Diet, Sodium-Restricted; Diuretics; Female; Follow | 1989 |
Schistosoma mansoni: tegumental surface alterations following oxamniquine treatment of infected mice.
Topics: Animals; Female; Male; Mice; Nitroquinolines; Oxamniquine; Schistosoma mansoni; Schistosomiasis mans | 1989 |
A new approach to the treatment of acute schistosomiasis.
Topics: Acute Disease; Adolescent; Adult; Animals; Child; Child, Preschool; Dexamethasone; Drug Synergism; D | 1989 |
Manson's schistosomiasis in Brazil: 11-year evaluation of successful disease control with oxamniquine.
Topics: Adolescent; Adult; Brazil; Child; Feces; Follow-Up Studies; Humans; Male; Middle Aged; Nitroquinolin | 1986 |
Pulmonary involvement in schistosomiasis mansoni.
Topics: Animals; Humans; Immune Complex Diseases; Lung; Male; Mice; Oxamniquine; Schistosomiasis mansoni | 1987 |
The "lung shift" in treated schistosomiasis. Bronchoalveolar lavage evidence of eosinophilic pneumonia.
Topics: Adult; Humans; Male; Oxamniquine; Pulmonary Alveoli; Pulmonary Eosinophilia; Schistosomiasis mansoni | 1986 |
Seizures associated with oxamniquine therapy.
Topics: Adult; Electroencephalography; Humans; Male; Nitroquinolines; Oxamniquine; Schistosomiasis mansoni; | 1986 |
Schistosoma mansoni: chemotherapy of infections of different ages.
Topics: Animals; Antimony Potassium Tartrate; Diphenylamine; Female; Hycanthone; Isothiocyanates; Mice; Mice | 1986 |
Evolution of the schistosomal hepatic lesions in mice after curative chemotherapy.
Topics: Animals; Female; Fluorescent Antibody Technique; Hycanthone; Liver; Male; Mice; Microscopy, Electron | 1986 |
Oxamniquine treatment for schistosomal polyposis: a 1-2 year follow-up study.
Topics: Adolescent; Adult; Child; Colonic Polyps; Follow-Up Studies; Humans; Intestinal Diseases, Parasitic; | 1986 |
Schistosomiasis in a mining area: intersectoral implications.
Topics: Adolescent; Adult; Animals; Child; Child, Preschool; Cost-Benefit Analysis; Democratic Republic of t | 1986 |
Ultrasonography of pancreatic schistosomiasis: a case report.
Topics: Child; Female; Humans; Laparotomy; Oxamniquine; Pancreatic Diseases; Schistosoma mansoni; Schistosom | 1986 |
Oxamniquine pharmacokinetics in hepatosplenic schistosomiasis in the Sudan.
Topics: Adult; Female; Half-Life; Humans; Kinetics; Liver Diseases, Parasitic; Male; Middle Aged; Nitroquino | 1987 |
The influence of anti-parasitic therapy on the course of the glomerulopathy associated with Schistosomiasis mansoni.
Topics: Humans; Hycanthone; Kidney; Kidney Diseases; Oxamniquine; Schistosomiasis mansoni; Schistosomicides | 1987 |
Immunity after treatment of human schistosomiasis mansoni. III. Long-term effects of treatment and retreatment.
Topics: Adolescent; Adult; Age Factors; Child; Female; Humans; Immunity; Immunity, Innate; Male; Middle Aged | 1987 |
Repeated mass treatment of schistosomiasis mansoni: experience in hyperendemic areas of Brazil. I. Parasitological effects and morbidity.
Topics: Adolescent; Adult; Age Factors; Brazil; Humans; Hypertension, Portal; Middle Aged; Nitroquinolines; | 1987 |
Human resistance to Schistosoma mansoni is associated with IgG reactivity to a 37-kDa larval surface antigen.
Topics: Adolescent; Animals; Antibodies, Helminth; Antigens, Helminth; Antigens, Surface; Child; Female; Hum | 1988 |
Tolerance of Kenyan Schistosoma mansoni to oxamniquine.
Topics: Administration, Oral; Animals; Child; Dose-Response Relationship, Drug; Drug Resistance; Female; Hum | 1987 |
Susceptibility of Schistosoma mansoni prevalent in Saudi Arabia to oxamniquine in experimentally infected mice.
Topics: Administration, Oral; Animals; Feces; Female; Liver; Male; Mice; Mice, Inbred Strains; Nitroquinolin | 1988 |
Analysis of worm burdens in experimental schistosomiasis.
Topics: Animals; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Male; Mice; Models, Bi | 1988 |
The separation of complement inhibitors from patients with schistosomiasis or Chagas' disease by gel filtration on Sephadex G-200: a preliminary study.
Topics: Chagas Disease; Chromatography, Gel; Complement Inactivator Proteins; Hot Temperature; Humans; Oxamn | 1988 |
Effect of anti-schistosomal treatment on schistosomal-specific nephropathy.
Topics: Adult; Antibodies, Helminth; Antigens, Helminth; Female; Follow-Up Studies; Glomerulonephritis; Glom | 1988 |
Repeated mass treatment of schistosomiasis mansoni: experience in hyperendemic areas of Brazil. II. Micro-level evaluation of results.
Topics: Adolescent; Animals; Biomphalaria; Brazil; Child; Disease Reservoirs; Feces; Humans; Nitroquinolines | 1988 |
[Effect of specific therapy on the levels of schistosomiasis mansoni infection].
Topics: Brazil; Drug Evaluation; Humans; Nitroquinolines; Oxamniquine; Schistosomiasis mansoni | 1987 |
Specific treatment of advanced schistosomiasis liver disease in man: favourable results.
Topics: Adolescent; Adult; Aged; Child; Drug Evaluation; Female; Hepatitis, Chronic; Hepatomegaly; Humans; L | 1987 |
[Action of oxamniquine on Schistosoma mansoni in mice experimentally infected with a strain from Kenya].
Topics: Animals; Drug Evaluation, Preclinical; Kenya; Male; Mice; Nitroquinolines; Oxamniquine; Schistosoma | 1987 |
Circulating antigens for assessing cure in schistosomiasis mansoni.
Topics: Adolescent; Adult; Antibodies, Helminth; Antigens, Helminth; Child; Enzyme-Linked Immunosorbent Assa | 1988 |
[A comprehensive health plan in combatting schistosomiasis in the State of Maranhão, Brazil].
Topics: Brazil; Carrier State; Health Education; Humans; Oxamniquine; Parasite Egg Count; Regional Health Pl | 1986 |
Schistosoma mansoni cationic egg antigens (CEF6): immunoserology with oxamniquine-treated patients and involvement of CEF6 in the circumoval precipitin reaction.
Topics: Adult; Animals; Antibodies, Helminth; Antigens, Helminth; Chromatography, Ion Exchange; Enzyme-Linke | 1988 |
Re: serious side effects of oxamniquine during the treatment of Schistosoma mansoni in Kenya.
Topics: Diagnosis, Differential; Duodenal Ulcer; Epilepsy; Humans; Nitroquinolines; Oxamniquine; Schistosomi | 1985 |
Schistosoma mansoni: reduced efficacy of chemotherapy in infected T-cell-deprived mice.
Topics: Animals; Antilymphocyte Serum; Diphenylamine; Hycanthone; Isothiocyanates; Mice; Mice, Inbred CBA; O | 1985 |
Effects of chemotherapy on mice submitted to multiple Schistosoma mansoni infections. A controlled randomized prospective study.
Topics: Administration, Oral; Animals; Antigens, Helminth; Bile Ducts, Intrahepatic; Female; Granuloma; Immu | 1985 |
Treatment of Schistosoma mansoni infection with oxamniquine in Riyadh, Saudi Arabia.
Topics: Humans; Nitroquinolines; Oxamniquine; Schistosoma mansoni; Schistosomiasis mansoni | 1985 |