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oxamniquine and Schistosomiasis haematobia

oxamniquine has been researched along with Schistosomiasis haematobia in 4 studies

Oxamniquine: An anthelmintic with schistosomicidal activity against Schistosoma mansoni, but not against other Schistosoma spp. Oxamniquine causes worms to shift from the mesenteric veins to the liver where the male worms are retained; the female worms return to the mesentery, but can no longer release eggs. (From Martindale, The Extra Pharmacopoeia, 31st ed, p121)
oxamniquine : A racemate comprising equimolar amounts of (R)- and (S)-oxamniquine. An anthelmintic, it is administered orally for the treatment of schistomiasis caused by Schistosoma mansoni (but not by other Schistosoma species); intramuscular administration is no longer used as it causes severe pain at the injection site.
{2-[(isopropylamino)methyl]-7-nitro-1,2,3,4-tetrahydroquinolin-6-yl}methanol : A member of the class of quinolines that is 1,2,3,4-tetrahydroquinoline which is substituted at positions 2, 6, and 7 by (isopropylamino)methyl, hydroxymethyl, and nitro groups, respectively.

Schistosomiasis haematobia: A human disease caused by the infection of parasitic worms SCHISTOSOMA HAEMATOBIUM. It is endemic in AFRICA and parts of the MIDDLE EAST. Tissue damages most often occur in the URINARY TRACT, specifically the URINARY BLADDER.

Research Excerpts

ExcerptRelevanceReference
"praziquantel was equally effective against both parasite species."2.66The effect of metrifonate in mixed Schistosoma haematobium and Schistosoma mansoni infections in humans. ( Doehring, E; Feldmeier, H; Poggensee, U, 1986)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19902 (50.00)18.7374
1990's1 (25.00)18.2507
2000's0 (0.00)29.6817
2010's1 (25.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Hess, J1
Panic, G1
Patra, M1
Mastrobuoni, L1
Spingler, B1
Roy, S1
Keiser, J1
Gasser, G1
de Jonge, N1
Schommer, G1
Feldmeier, H2
Krijger, FW1
Dafalla, AA1
Bienzle, U1
Deelder, AM1
Doehring, E1
Poggensee, U1
Creasey, AM1
Taylor, P1
Thomas, JE1

Trials

3 trials available for oxamniquine and Schistosomiasis haematobia

ArticleYear
Mixed Schistosoma haematobium and S. mansoni infection: effect of different treatments on the serum level of circulating anodic antigen (CAA).
    Acta tropica, 1990, Volume: 48, Issue:1

    Topics: Animals; Antigens, Helminth; Child; Enzyme-Linked Immunosorbent Assay; Feces; Humans; Male; Oxamniqu

1990
The effect of metrifonate in mixed Schistosoma haematobium and Schistosoma mansoni infections in humans.
    The American journal of tropical medicine and hygiene, 1986, Volume: 35, Issue:2

    Topics: Adolescent; Child; Clinical Trials as Topic; Feces; Humans; Lung; Male; Oxamniquine; Parasite Egg Co

1986
Dosage trial of a combination of oxamniquine and praziquantel in the treatment of schistosomiasis in Zimbabwean schoolchildren.
    The Central African journal of medicine, 1986, Volume: 32, Issue:7

    Topics: Adolescent; Child; Clinical Trials as Topic; Drug Synergism; Drug Therapy, Combination; Female; Huma

1986

Other Studies

1 other study available for oxamniquine and Schistosomiasis haematobia

ArticleYear
Ferrocenyl, Ruthenocenyl, and Benzyl Oxamniquine Derivatives with Cross-Species Activity against Schistosoma mansoni and Schistosoma haematobium.
    ACS infectious diseases, 2017, 09-08, Volume: 3, Issue:9

    Topics: Animals; Anthelmintics; Chemistry, Pharmaceutical; Disease Models, Animal; Female; Male; Mice; Organ

2017