oxamniquine has been researched along with Onchocerciasis in 2 studies
Oxamniquine: An anthelmintic with schistosomicidal activity against Schistosoma mansoni, but not against other Schistosoma spp. Oxamniquine causes worms to shift from the mesenteric veins to the liver where the male worms are retained; the female worms return to the mesentery, but can no longer release eggs. (From Martindale, The Extra Pharmacopoeia, 31st ed, p121)
oxamniquine : A racemate comprising equimolar amounts of (R)- and (S)-oxamniquine. An anthelmintic, it is administered orally for the treatment of schistomiasis caused by Schistosoma mansoni (but not by other Schistosoma species); intramuscular administration is no longer used as it causes severe pain at the injection site.
{2-[(isopropylamino)methyl]-7-nitro-1,2,3,4-tetrahydroquinolin-6-yl}methanol : A member of the class of quinolines that is 1,2,3,4-tetrahydroquinoline which is substituted at positions 2, 6, and 7 by (isopropylamino)methyl, hydroxymethyl, and nitro groups, respectively.
Onchocerciasis: Infection with nematodes of the genus ONCHOCERCA. Characteristics include the presence of firm subcutaneous nodules filled with adult worms, PRURITUS, and ocular lesions.
| Excerpt | Relevance | Reference |
|---|---|---|
| " The introduction of oxamniquine and praziquantel constitutes a break through in the treatment of intestinal and urogenital schistosomiasis." | 4.76 | [Present status of the treatment of helminthiasis]. ( Coulaud, JP, 1984) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Coulaud, JP | 1 |
| Kale, O | 1 |
1 review available for oxamniquine and Onchocerciasis
| Article | Year |
|---|---|
[Present status of the treatment of helminthiasis].
Topics: Albendazole; Anthelmintics; Benzimidazoles; Cestode Infections; Echinococcosis; Helminthiasis; Human | 1984 |
1 trial available for oxamniquine and Onchocerciasis
| Article | Year |
|---|---|
Small-scale trials of six drugs against Onchocerca volvulus.
Topics: Adult; Aged; Anthelmintics; Drug Evaluation; Female; Filaricides; Humans; Male; Mebendazole; Metroni | 1978 |