oxamniquine has been researched along with Liver Cirrhosis in 3 studies
Oxamniquine: An anthelmintic with schistosomicidal activity against Schistosoma mansoni, but not against other Schistosoma spp. Oxamniquine causes worms to shift from the mesenteric veins to the liver where the male worms are retained; the female worms return to the mesentery, but can no longer release eggs. (From Martindale, The Extra Pharmacopoeia, 31st ed, p121)
oxamniquine : A racemate comprising equimolar amounts of (R)- and (S)-oxamniquine. An anthelmintic, it is administered orally for the treatment of schistomiasis caused by Schistosoma mansoni (but not by other Schistosoma species); intramuscular administration is no longer used as it causes severe pain at the injection site.
{2-[(isopropylamino)methyl]-7-nitro-1,2,3,4-tetrahydroquinolin-6-yl}methanol : A member of the class of quinolines that is 1,2,3,4-tetrahydroquinoline which is substituted at positions 2, 6, and 7 by (isopropylamino)methyl, hydroxymethyl, and nitro groups, respectively.
Liver Cirrhosis: Liver disease in which the normal microcirculation, the gross vascular anatomy, and the hepatic architecture have been variably destroyed and altered with fibrous septa surrounding regenerated or regenerating parenchymal nodules.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The course of hepatosplenic schistosomiasis after mass chemotherapy with oxamniquine has been rarely reported." | 7.73 | Ultrasound and clinical investigation of hepatosplenic schistosomiasis: evaluation of splenomegaly and liver fibrosis four years after mass chemotherapy with oxamniquine. ( Antunes, CM; Cota, GF; Lambertucci, JR; Pinto-Silva, RA, 2006) |
| "The course of hepatosplenic schistosomiasis after mass chemotherapy with oxamniquine has been rarely reported." | 3.73 | Ultrasound and clinical investigation of hepatosplenic schistosomiasis: evaluation of splenomegaly and liver fibrosis four years after mass chemotherapy with oxamniquine. ( Antunes, CM; Cota, GF; Lambertucci, JR; Pinto-Silva, RA, 2006) |
| "Treatment with oxamniquine resulted in near total eradication of S." | 1.28 | Evaluation of hepatic fibrosis after oxamniquine therapy of murine schistosomiasis. ( Girgis, NI; Ishak, EA; Khayyal, MT; Mansour, MM; Morcos, SH; Saleh, S, 1992) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (33.33) | 18.2507 |
| 2000's | 2 (66.67) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Cota, GF | 1 |
| Pinto-Silva, RA | 1 |
| Antunes, CM | 1 |
| Lambertucci, JR | 1 |
| Andrade, ZA | 1 |
| Baptista, AP | 1 |
| Santana, TS | 1 |
| Morcos, SH | 1 |
| Mansour, MM | 1 |
| Khayyal, MT | 1 |
| Saleh, S | 1 |
| Ishak, EA | 1 |
| Girgis, NI | 1 |
3 other studies available for oxamniquine and Liver Cirrhosis
| Article | Year |
|---|---|
Ultrasound and clinical investigation of hepatosplenic schistosomiasis: evaluation of splenomegaly and liver fibrosis four years after mass chemotherapy with oxamniquine.
Topics: Adolescent; Adult; Alcoholism; Female; Humans; Liver Cirrhosis; Logistic Models; Male; Multivariate | 2006 |
Remodeling of hepatic vascular changes after specific chemotherapy of schistosomal periportal fibrosis.
Topics: Animals; Anthelmintics; Chronic Disease; Disease Models, Animal; Female; Granuloma; Humans; Liver Ci | 2006 |
Evaluation of hepatic fibrosis after oxamniquine therapy of murine schistosomiasis.
Topics: Animals; Hydroxyproline; Liver; Liver Cirrhosis; Male; Mice; Oxamniquine; Parasite Egg Count; Schist | 1992 |