oxamniquine has been researched along with Intestinal Diseases, Parasitic in 10 studies
Oxamniquine: An anthelmintic with schistosomicidal activity against Schistosoma mansoni, but not against other Schistosoma spp. Oxamniquine causes worms to shift from the mesenteric veins to the liver where the male worms are retained; the female worms return to the mesentery, but can no longer release eggs. (From Martindale, The Extra Pharmacopoeia, 31st ed, p121)
oxamniquine : A racemate comprising equimolar amounts of (R)- and (S)-oxamniquine. An anthelmintic, it is administered orally for the treatment of schistomiasis caused by Schistosoma mansoni (but not by other Schistosoma species); intramuscular administration is no longer used as it causes severe pain at the injection site.
{2-[(isopropylamino)methyl]-7-nitro-1,2,3,4-tetrahydroquinolin-6-yl}methanol : A member of the class of quinolines that is 1,2,3,4-tetrahydroquinoline which is substituted at positions 2, 6, and 7 by (isopropylamino)methyl, hydroxymethyl, and nitro groups, respectively.
Intestinal Diseases, Parasitic: Infections of the INTESTINES with PARASITES, commonly involving PARASITIC WORMS. Infections with roundworms (NEMATODE INFECTIONS) and tapeworms (CESTODE INFECTIONS) are also known as HELMINTHIASIS.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Oxamniquine proved to be an efficient drug for the treatment of Schistosoma mansoni in adults." | 6.65 | A preliminary report on the treatment of intestinal schistosomiasis with oxamniquine. ( Shafei, AZ, 1979) |
| " The introduction of oxamniquine and praziquantel constitutes a break through in the treatment of intestinal and urogenital schistosomiasis." | 4.76 | [Present status of the treatment of helminthiasis]. ( Coulaud, JP, 1984) |
| "Oxamniquine proved to be an efficient drug for the treatment of Schistosoma mansoni in adults." | 2.65 | A preliminary report on the treatment of intestinal schistosomiasis with oxamniquine. ( Shafei, AZ, 1979) |
| " Several dosage regimens have been tried but a total dose of 40 mg/kg over two days in two equally divided doses has been found to have an effective therapeutic action on the polypi, with correction of the anaemia, hypoalbuminaemia and serum iron." | 1.26 | Chemotherapy of schistosomal colonic polyposis with oxamniquine. ( Abaza, HH; Hammouda, N; Rabbo, HA; Shafei, AZ, 1978) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 10 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Coulaud, JP | 1 |
| Massoud, A | 1 |
| Hafez, AS | 1 |
| Hussein, MM | 1 |
| Abdel Karim, AH | 1 |
| el Nahaal, A | 1 |
| Lambertucci, JR | 1 |
| Greco, DB | 1 |
| Pedroso, ER | 1 |
| da Costa Rocha, MO | 1 |
| Salazar, HM | 1 |
| de Lima, DP | 1 |
| García Goyco, C | 1 |
| Torres Borges, A | 1 |
| Guimarães, RX | 1 |
| Tchakerian, A | 1 |
| Dias, LC | 1 |
| de Almeida, FM | 1 |
| Vilela, MP | 1 |
| Cabeca, M | 1 |
| Takeda, AK | 1 |
| Shafei, AZ | 2 |
| Ambroise-Thomas, P | 1 |
| Goullier, A | 1 |
| Bonneville, B | 1 |
| Couderc, P | 1 |
| Abaza, HH | 1 |
| Hammouda, N | 1 |
| Rabbo, HA | 1 |
| Koura, M | 1 |
| Gaber, A | 1 |
| Abdel-Meguid, M | 1 |
| Saif, M | 1 |
| el-Masry, NA | 1 |
| Farid, Z | 1 |
| Bassily, S | 1 |
| Kilpatrick, ME | 1 |
| Watten, RH | 1 |
| Girgis, NI | 1 |
1 review available for oxamniquine and Intestinal Diseases, Parasitic
| Article | Year |
|---|---|
[Present status of the treatment of helminthiasis].
Topics: Albendazole; Anthelmintics; Benzimidazoles; Cestode Infections; Echinococcosis; Helminthiasis; Human | 1984 |
2 trials available for oxamniquine and Intestinal Diseases, Parasitic
| Article | Year |
|---|---|
A double blind trial with oxamniquine in chronic schistosomiasis mansoni.
Topics: Adolescent; Child; Chronic Disease; Clinical Trials as Topic; Double-Blind Method; Feces; Female; Hu | 1982 |
A preliminary report on the treatment of intestinal schistosomiasis with oxamniquine.
Topics: Adolescent; Adult; Female; Humans; Intestinal Diseases, Parasitic; Male; Middle Aged; Nitroquinoline | 1979 |
7 other studies available for oxamniquine and Intestinal Diseases, Parasitic
| Article | Year |
|---|---|
Pharmacokinetic studies on praziquantel and oxamniquine in intestinal schistosomiasis.
Topics: Adolescent; Humans; Intestinal Diseases, Parasitic; Isoquinolines; Kinetics; Male; Nitroquinolines; | 1984 |
[Schistosomiasis: clinical spectrum of the disease and response to oxamniquine treatment in chronic infections].
Topics: Adolescent; Adult; Child; Female; Humans; Intestinal Diseases, Parasitic; Liver Diseases, Parasitic; | 1982 |
[Resistance to hycanthone and oxamniquine in patients with a clinical hepato-intestinal form of schistosomiasis].
Topics: Adult; Animals; Drug Resistance; Female; Humans; Hycanthone; Intestinal Diseases, Parasitic; Liver D | 1979 |
[Schistosoma mansoni bilharziasis evolving 30 years after infestation].
Topics: Humans; Intestinal Diseases, Parasitic; Male; Middle Aged; Niridazole; Oxamniquine; Schistosoma mans | 1979 |
Chemotherapy of schistosomal colonic polyposis with oxamniquine.
Topics: Adult; Colonic Neoplasms; Female; Humans; Intestinal Diseases, Parasitic; Intestinal Polyps; Male; N | 1978 |
Treatment of intestinal bilharziasis with oral oxamniquine (a preliminary report).
Topics: Administration, Oral; Animals; Cricetinae; Female; Haplorhini; Humans; Intestinal Diseases, Parasiti | 1975 |
Oxamniquine treatment for schistosomal polyposis: a 1-2 year follow-up study.
Topics: Adolescent; Adult; Child; Colonic Polyps; Follow-Up Studies; Humans; Intestinal Diseases, Parasitic; | 1986 |