oxamniquine has been researched along with Disease Models, Animal in 5 studies
Oxamniquine: An anthelmintic with schistosomicidal activity against Schistosoma mansoni, but not against other Schistosoma spp. Oxamniquine causes worms to shift from the mesenteric veins to the liver where the male worms are retained; the female worms return to the mesentery, but can no longer release eggs. (From Martindale, The Extra Pharmacopoeia, 31st ed, p121)
oxamniquine : A racemate comprising equimolar amounts of (R)- and (S)-oxamniquine. An anthelmintic, it is administered orally for the treatment of schistomiasis caused by Schistosoma mansoni (but not by other Schistosoma species); intramuscular administration is no longer used as it causes severe pain at the injection site.
{2-[(isopropylamino)methyl]-7-nitro-1,2,3,4-tetrahydroquinolin-6-yl}methanol : A member of the class of quinolines that is 1,2,3,4-tetrahydroquinoline which is substituted at positions 2, 6, and 7 by (isopropylamino)methyl, hydroxymethyl, and nitro groups, respectively.
Disease Models, Animal: Naturally-occurring or experimentally-induced animal diseases with pathological processes analogous to human diseases.
Excerpt | Relevance | Reference |
---|---|---|
"Praziquantel was the most effective drug; a dose of 100 mg/kg given orally for 5 days resulted in a 95% reduction in worm burdens." | 1.28 | Experimental chemotherapy of Schistosoma curassoni in mice. ( Hilderson, H; Rollinson, D; Southgate, VR; Vercruysse, J, 1989) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 2 (40.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 1 (20.00) | 29.6817 |
2010's | 2 (40.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Kinnamon, KE | 1 |
Steck, EA | 1 |
Hanson, WL | 1 |
Chapman, WL | 1 |
Hess, J | 1 |
Panic, G | 1 |
Patra, M | 1 |
Mastrobuoni, L | 1 |
Spingler, B | 1 |
Roy, S | 1 |
Keiser, J | 1 |
Gasser, G | 1 |
Yuen, T | 1 |
Iqbal, J | 1 |
Zhu, LL | 1 |
Sun, L | 1 |
Lin, A | 1 |
Zhao, H | 1 |
Liu, J | 1 |
Mistry, PK | 1 |
Zaidi, M | 1 |
Andrade, ZA | 1 |
Baptista, AP | 1 |
Santana, TS | 1 |
Vercruysse, J | 1 |
Southgate, VR | 1 |
Rollinson, D | 1 |
Hilderson, H | 1 |
5 other studies available for oxamniquine and Disease Models, Animal
Article | Year |
---|---|
In search of anti-Trypanosoma cruzi drugs: new leads from a mouse model.
Topics: 5-Amino-3-((5-nitro-2-furyl)vinyl)-1,2,4-oxadiazole; Aminoquinolines; Animals; Chagas Disease; Disea | 1977 |
Ferrocenyl, Ruthenocenyl, and Benzyl Oxamniquine Derivatives with Cross-Species Activity against Schistosoma mansoni and Schistosoma haematobium.
Topics: Animals; Anthelmintics; Chemistry, Pharmaceutical; Disease Models, Animal; Female; Male; Mice; Organ | 2017 |
Disease-drug pairs revealed by computational genomic connectivity mapping on GBA1 deficient, Gaucher disease mice.
Topics: Albendazole; Animals; Anthelmintics; Computational Biology; Disease Models, Animal; Drug Discovery; | 2012 |
Remodeling of hepatic vascular changes after specific chemotherapy of schistosomal periportal fibrosis.
Topics: Animals; Anthelmintics; Chronic Disease; Disease Models, Animal; Female; Granuloma; Humans; Liver Ci | 2006 |
Experimental chemotherapy of Schistosoma curassoni in mice.
Topics: Animals; Disease Models, Animal; Female; Hycanthone; Male; Mice; Nitroquinolines; Oxamniquine; Prazi | 1989 |