oxamniquine has been researched along with Bilharziasis in 134 studies
Oxamniquine: An anthelmintic with schistosomicidal activity against Schistosoma mansoni, but not against other Schistosoma spp. Oxamniquine causes worms to shift from the mesenteric veins to the liver where the male worms are retained; the female worms return to the mesentery, but can no longer release eggs. (From Martindale, The Extra Pharmacopoeia, 31st ed, p121)
oxamniquine : A racemate comprising equimolar amounts of (R)- and (S)-oxamniquine. An anthelmintic, it is administered orally for the treatment of schistomiasis caused by Schistosoma mansoni (but not by other Schistosoma species); intramuscular administration is no longer used as it causes severe pain at the injection site.
{2-[(isopropylamino)methyl]-7-nitro-1,2,3,4-tetrahydroquinolin-6-yl}methanol : A member of the class of quinolines that is 1,2,3,4-tetrahydroquinoline which is substituted at positions 2, 6, and 7 by (isopropylamino)methyl, hydroxymethyl, and nitro groups, respectively.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Randomized single-blind comparative trials of the newer antischistosomal drugs praziquantel and oxamniquine were undertaken at Mwanza, Tanzania, an area coendemic for schistosomiasis mansoni and haematobium." | 9.05 | Randomized comparative trials of single doses of the newer antischistosomal drugs at Mwanza, Tanzania. I. Praziquantel and oxamniquine for the treatment of schistosomiasis mansoni. ( Asila, J; Chimbe, A; Rugemalila, JB, 1984) |
| "The course of hepatosplenic schistosomiasis after mass chemotherapy with oxamniquine has been rarely reported." | 7.73 | Ultrasound and clinical investigation of hepatosplenic schistosomiasis: evaluation of splenomegaly and liver fibrosis four years after mass chemotherapy with oxamniquine. ( Antunes, CM; Cota, GF; Lambertucci, JR; Pinto-Silva, RA, 2006) |
| "The authors study the results of a treatment of 700 cases of bilharziasis seen in Paris and in two foci in Togo, by oxamniquine, oltipraz or praziquantel." | 7.66 | [Treatment of 700 cases of bilharziasis with the new drugs oxamniquine, oltipraz, praziquantel]. ( Ancelle, T; Dupouy-Camet, J; Faurant, C; Heyer, F; Keita, A; Lapierre, J; Tourte-Schaefer, C, 1983) |
| "Fourteen patients with active schistosomiasis mansoni in spite of previous treatment with oxamniquine and/or hycanthone were treated with praziquantel, single oral dose of 45 to 50 mg/kg body-weight." | 7.66 | Use of praziquantel in patients with schistosomiasis mansoni previously treated with oxamniquine and/or hycanthone: resistance of Schistosoma mansoni to schistosomicidal agents. ( de Jesus Pedro, R; de Souza Dias, LC; Deberaldini, ER, 1982) |
| "The object of the study was to identify any potential therapeutic advantage in using the two antischistosomal drugs, oxamniquine and praziquantel, in combination rather than separately, in the treatment of schistosomiasis." | 7.66 | The treatment of experimental schistosomiasis with a combination of oxamniquine and praziquantel. ( Brammer, KW; Shaw, JR, 1983) |
| "Oral oxamniquine was tested as a control strategy for endemic schistosomiasis in a rural area of Bahia, Brazil." | 7.66 | A three year follow-up of chemotherapy with oxamniquine in a Brazilian community with endemic schistosomiasis mansoni. ( Barreto, ML; Hoff, R; Lehman, JS; Maguire, JH; Mota, EA; Mott, KE; Muniz, TM; Sherlock, I; Silva, JT; Sleigh, AC, 1981) |
| "Oxamniquine proved to be an efficient drug for the treatment of Schistosoma mansoni in adults." | 6.65 | A preliminary report on the treatment of intestinal schistosomiasis with oxamniquine. ( Shafei, AZ, 1979) |
| "Human schistosomiasis is a neglected tropical disease caused by Schistosoma mansoni, S." | 5.91 | Oxamniquine derivatives overcome Praziquantel treatment limitations for Schistosomiasis. ( Alwan, SN; LoVerde, PT; McHardy, SF; Rhodes, J; Taylor, AB; Tidwell, M, 2023) |
| "Schistosomiasis is a disease of poverty affecting millions of people." | 5.56 | Multidisciplinary Preclinical Investigations on Three Oxamniquine Analogues as New Drug Candidates for Schistosomiasis*. ( Buchter, V; Gasser, G; Keiser, J; Ladaycia, A; Lepeltier, E; Mouvet, F; Ong, YC; Rothlisberger, U, 2020) |
| "A schedule of repeated chemotherapy with oxamniquine, consisting of biannual treatment of school-aged (7-13 years) children and annual treatment of all other age groups, was used in a representative rural village from a highly endemic area of schistosomiasis in Pernambuco." | 5.08 | Schistosomiasis control based on repeated chemotherapy in a rural village of the sugar-cane zone in northeast Brazil. ( Barbosa, CS; Moza, PG; Pieri, OS, 1998) |
| "Randomized single-blind comparative trials of the newer antischistosomal drugs praziquantel and oxamniquine were undertaken at Mwanza, Tanzania, an area coendemic for schistosomiasis mansoni and haematobium." | 5.05 | Randomized comparative trials of single doses of the newer antischistosomal drugs at Mwanza, Tanzania. I. Praziquantel and oxamniquine for the treatment of schistosomiasis mansoni. ( Asila, J; Chimbe, A; Rugemalila, JB, 1984) |
| " The introduction of oxamniquine and praziquantel constitutes a break through in the treatment of intestinal and urogenital schistosomiasis." | 4.76 | [Present status of the treatment of helminthiasis]. ( Coulaud, JP, 1984) |
| "Hycanthone (HYC) is a retired drug formerly used to treat schistosomiasis caused by infection from Schistosoma mansoni and S." | 3.96 | Molecular basis for hycanthone drug action in schistosome parasites. ( Cao, X; Guzman, M; LoVerde, PT; McHardy, SF; Rugel, A; Tarpley, RS; Taylor, AB, 2020) |
| " Oxamniquine was used to treat Brazilian schistosomiasis patients (mid-1970s to mid-2000s) and several cases of parasite infections resistant to treatment were recorded." | 3.83 | Independent origins of loss-of-function mutations conferring oxamniquine resistance in a Brazilian schistosome population. ( Anderson, TJ; Assis, RR; Cao, X; Chevalier, FD; Eng, N; Hart, PJ; Holloway, SP; Le Clec'h, W; LoVerde, PT; Oliveira, G; Rugel, AR, 2016) |
| "The course of hepatosplenic schistosomiasis after mass chemotherapy with oxamniquine has been rarely reported." | 3.73 | Ultrasound and clinical investigation of hepatosplenic schistosomiasis: evaluation of splenomegaly and liver fibrosis four years after mass chemotherapy with oxamniquine. ( Antunes, CM; Cota, GF; Lambertucci, JR; Pinto-Silva, RA, 2006) |
| "Fourteen patients with active schistosomiasis mansoni in spite of previous treatment with oxamniquine and/or hycanthone were treated with praziquantel, single oral dose of 45 to 50 mg/kg body-weight." | 3.66 | Use of praziquantel in patients with schistosomiasis mansoni previously treated with oxamniquine and/or hycanthone: resistance of Schistosoma mansoni to schistosomicidal agents. ( de Jesus Pedro, R; de Souza Dias, LC; Deberaldini, ER, 1982) |
| "A patient with membranoproliferative glomerulonephritis and renal dysfunction caused by Schistosoma mansoni was treated with oxamniquine." | 3.66 | Treatment of schistosome-induced glomerulonephritis. A case report and review of the literature. ( Libbey, NP; Ott, BR; Ryter, RJ; Trebbin, WM, 1983) |
| "The object of the study was to identify any potential therapeutic advantage in using the two antischistosomal drugs, oxamniquine and praziquantel, in combination rather than separately, in the treatment of schistosomiasis." | 3.66 | The treatment of experimental schistosomiasis with a combination of oxamniquine and praziquantel. ( Brammer, KW; Shaw, JR, 1983) |
| "The authors study the results of a treatment of 700 cases of bilharziasis seen in Paris and in two foci in Togo, by oxamniquine, oltipraz or praziquantel." | 3.66 | [Treatment of 700 cases of bilharziasis with the new drugs oxamniquine, oltipraz, praziquantel]. ( Ancelle, T; Dupouy-Camet, J; Faurant, C; Heyer, F; Keita, A; Lapierre, J; Tourte-Schaefer, C, 1983) |
| "Oral oxamniquine was tested as a control strategy for endemic schistosomiasis in a rural area of Bahia, Brazil." | 3.66 | A three year follow-up of chemotherapy with oxamniquine in a Brazilian community with endemic schistosomiasis mansoni. ( Barreto, ML; Hoff, R; Lehman, JS; Maguire, JH; Mota, EA; Mott, KE; Muniz, TM; Sherlock, I; Silva, JT; Sleigh, AC, 1981) |
| "In confirmation of an earlier study, it was found that in mice infected with Schistosoma mansoni hepatocellular carcinomas are induced by hycanthone, an antischistosomal drug and potent frameshift mutagen." | 3.65 | Long-term hepatocellular effects of hycanthone and of two other anti-Schistosomal drugs in mice infected with Schistosoma mansoni. ( Bueding, E; Haese, WH, 1976) |
| "Human schistosomiasis is a debilitating, life-threatening disease affecting more than 229 million people in as many as 78 countries." | 2.72 | Rational approach to drug discovery for human schistosomiasis. ( Alwan, SN; Anderson, TJ; Chevalier, FD; LoVerde, PT; McHardy, SF; Rhodes, J; Taylor, AB, 2021) |
| "Oxamniquine proved to be an efficient drug for the treatment of Schistosoma mansoni in adults." | 2.65 | A preliminary report on the treatment of intestinal schistosomiasis with oxamniquine. ( Shafei, AZ, 1979) |
| "Currently, the main forms of treatment used for schistosomiasis are praziquantel (PZQ) and oxaminiquine (OXA)." | 2.55 | Schistosomiasis: Drugs used and treatment strategies. ( Aguilera, CSB; Ângelos, MA; da Silva, RMF; de Melo, CG; Fontes, DAF; Neto, PJR; Rolim, LA; Silva, LCPBB; Siqueira, LDP; Timóteo, TRR, 2017) |
| "Schistosomiasis is a curable parasitic infection that, if left untreated, can persist for 30 years even though the parasite cannot reproduce in its human host." | 2.38 | Schistosomiasis. ( Lucey, DR; Maguire, JH, 1993) |
| "Human schistosomiasis is a neglected tropical disease caused by Schistosoma mansoni, S." | 1.91 | Oxamniquine derivatives overcome Praziquantel treatment limitations for Schistosomiasis. ( Alwan, SN; LoVerde, PT; McHardy, SF; Rhodes, J; Taylor, AB; Tidwell, M, 2023) |
| "Schistosomiasis is a neglected tropical disease with more than 200 million new infections per year." | 1.72 | Disulfiram and dithiocarbamate analogues demonstrate promising antischistosomal effects. ( Gallinger, TL; Grevelding, CG; Grünweller, A; Haeberlein, S; Lange-Grünweller, K; Mäder, P; Rennar, GA; Schlitzer, M, 2022) |
| "Oxamniquine is a pro-drug converted into its active form by schistosomal sulfotransferase." | 1.56 | Schistosomal Sulfotransferase Interaction with Oxamniquine Involves Hybrid Mechanism of Induced-fit and Conformational Selection. ( Ezebuo, FC; Uzochukwu, IC, 2020) |
| "Schistosomiasis is a disease of poverty affecting millions of people." | 1.56 | Multidisciplinary Preclinical Investigations on Three Oxamniquine Analogues as New Drug Candidates for Schistosomiasis*. ( Buchter, V; Gasser, G; Keiser, J; Ladaycia, A; Lepeltier, E; Mouvet, F; Ong, YC; Rothlisberger, U, 2020) |
| "Currently there is only one method of treatment for human schistosomiasis, the drug praziquantel." | 1.56 | An iterative process produces oxamniquine derivatives that kill the major species of schistosomes infecting humans. ( Alwan, SN; Anderson, TJC; Cao, X; Chevalier, FD; Guzman, MA; Holloway, SP; Kovalskyy, DP; LoVerde, PT; McHardy, SF; Rugel, AR; Tarpley, RS; Taylor, AB, 2020) |
| "Schistosomiasis is one of the most harmful parasitic diseases worldwide, praziquantel being the only drug in widespread use to treat it." | 1.48 | Assessment of tegumental damage to Schistosoma mansoni and S. haematobium after in vitro exposure to ferrocenyl, ruthenocenyl and benzyl derivatives of oxamniquine using scanning electron microscopy. ( Buchter, V; Gasser, G; Hess, J; Keiser, J, 2018) |
| "Schistosomiasis was documented in group I by identifying schistosoma eggs in urine, stool or rectal mucosal biopsy." | 1.31 | Impact of schistosomiasis on patient and graft outcome after renal transplantation: 10 years' follow-up. ( Baz, ME; El-Agroudy, AE; Ghoneim, MA; Mahmoud, KM; Mostafa, FE; Shokeir, AA; Sobh, MA, 2001) |
| "Praziquantel was the most effective drug; a dose of 100 mg/kg given orally for 5 days resulted in a 95% reduction in worm burdens." | 1.28 | Experimental chemotherapy of Schistosoma curassoni in mice. ( Hilderson, H; Rollinson, D; Southgate, VR; Vercruysse, J, 1989) |
| "Intestinal schistosomiasis is highly prevalent among the labourers and their families in many of the miners' villages in Maniema, Zaire." | 1.27 | Cost-effectiveness of different ways of controlling intestinal schistosomiasis: a case study. ( Polderman, AM, 1984) |
| "The high prevalence of hepatomegaly (over 80%) and of splenomegaly (over 15%) contrasted with rates of 10% and 1%, respectively, in a non-endemic area." | 1.27 | Three-year prospective study of the evolution of Manson's schistosomiasis in north-east Brazil. ( Barreto, ML; Hoff, R; Maguire, JH; Mota, EA; Mott, KE; Sherlock, I; Sleigh, AC; Weller, TH, 1985) |
| "In oxamniquine-treated mice there was a delayed migration from the skin relative to controls and fewer parasites in total appeared to reach the lungs." | 1.27 | Induction of resistance to Schistosoma mansoni in mice by chemotherapy: migration of schistosomula in primary and challenge infections. ( Bickle, QD; Mastin, AJ; Wilson, RA, 1985) |
| "Oxamniquine was given in single daily doses of 20 mg/kg of body weight for either two or three days and cured 50% and 85%, respectively, of subjects treated; ova excretion was reduced by 86%-93% for up to 12 months." | 1.26 | Clinical characteristics and response to therapy in Egyptian children heavily infected with Schistosoma mansoni. ( Abdel-Wahab, F; El-Sahly, A; Merritt, W; Strickland, GT, 1982) |
| " Several dosage regimens have been tried but a total dose of 40 mg/kg over two days in two equally divided doses has been found to have an effective therapeutic action on the polypi, with correction of the anaemia, hypoalbuminaemia and serum iron." | 1.26 | Chemotherapy of schistosomal colonic polyposis with oxamniquine. ( Abaza, HH; Hammouda, N; Rabbo, HA; Shafei, AZ, 1978) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 112 (83.58) | 18.7374 |
| 1990's | 4 (2.99) | 18.2507 |
| 2000's | 6 (4.48) | 29.6817 |
| 2010's | 4 (2.99) | 24.3611 |
| 2020's | 8 (5.97) | 2.80 |
| Authors | Studies |
|---|---|
| Cheuka, PM | 1 |
| Rennar, GA | 1 |
| Gallinger, TL | 1 |
| Mäder, P | 1 |
| Lange-Grünweller, K | 1 |
| Haeberlein, S | 1 |
| Grünweller, A | 1 |
| Grevelding, CG | 1 |
| Schlitzer, M | 1 |
| Alwan, SN | 3 |
| Taylor, AB | 4 |
| Rhodes, J | 2 |
| Tidwell, M | 1 |
| McHardy, SF | 4 |
| LoVerde, PT | 5 |
| Guzman, M | 1 |
| Rugel, A | 1 |
| Tarpley, RS | 2 |
| Cao, X | 3 |
| Guzman, MA | 1 |
| Rugel, AR | 2 |
| Chevalier, FD | 3 |
| Kovalskyy, DP | 1 |
| Holloway, SP | 2 |
| Anderson, TJC | 1 |
| Buchter, V | 2 |
| Ong, YC | 1 |
| Mouvet, F | 1 |
| Ladaycia, A | 1 |
| Lepeltier, E | 1 |
| Rothlisberger, U | 1 |
| Keiser, J | 3 |
| Gasser, G | 2 |
| Anderson, TJ | 2 |
| Siqueira, LDP | 1 |
| Fontes, DAF | 1 |
| Aguilera, CSB | 1 |
| Timóteo, TRR | 1 |
| Ângelos, MA | 1 |
| Silva, LCPBB | 1 |
| de Melo, CG | 1 |
| Rolim, LA | 1 |
| da Silva, RMF | 1 |
| Neto, PJR | 1 |
| Stingl, P | 1 |
| Stingl, T | 1 |
| Hess, J | 1 |
| Ezebuo, FC | 1 |
| Uzochukwu, IC | 1 |
| Le Clec'h, W | 1 |
| Eng, N | 1 |
| Assis, RR | 1 |
| Oliveira, G | 1 |
| Hart, PJ | 1 |
| Utzinger, J | 1 |
| Shuhua, X | 1 |
| Tanner, M | 1 |
| Singer, BH | 1 |
| Fenwick, A | 1 |
| Savioli, L | 1 |
| Engels, D | 1 |
| Robert Bergquist, N | 1 |
| Todd, MH | 1 |
| Cota, GF | 1 |
| Pinto-Silva, RA | 1 |
| Antunes, CM | 1 |
| Lambertucci, JR | 4 |
| Coulaud, JP | 2 |
| De Cock, KM | 1 |
| Rugemalila, JB | 1 |
| Asila, J | 1 |
| Chimbe, A | 1 |
| Ayele, T | 1 |
| Gupta, KK | 1 |
| Pugh, RN | 2 |
| Teesdale, CH | 2 |
| Efthimiou, J | 1 |
| Denning, D | 1 |
| Scrimgeour, EM | 1 |
| Polderman, AM | 2 |
| Popiel, I | 3 |
| Erasmus, DA | 3 |
| Massoud, A | 1 |
| Hafez, AS | 1 |
| Hussein, MM | 2 |
| Abdel Karim, AH | 1 |
| el Nahaal, A | 1 |
| Valadares, TE | 1 |
| Pereira, LH | 2 |
| de Almeida, MA | 1 |
| Andrade, ZA | 2 |
| Hammouda, NA | 2 |
| El-Ridi, AM | 1 |
| Abu Senna, HO | 1 |
| Nasr, NT | 1 |
| El-Sawi, MF | 1 |
| El-Sawi, M | 1 |
| Salama, MM | 1 |
| Madwar, MA | 1 |
| El-Fekhakh, EA | 1 |
| Montasser, MF | 1 |
| Ahmed, MS | 1 |
| Ahmed, SE | 1 |
| Krajden, S | 1 |
| Keystone, JS | 1 |
| Glenn, C | 1 |
| Lapierre, J | 1 |
| Keita, A | 1 |
| Faurant, C | 1 |
| Heyer, F | 1 |
| Tourte-Schaefer, C | 1 |
| Ancelle, T | 1 |
| Dupouy-Camet, J | 1 |
| Shaw, JR | 1 |
| Brammer, KW | 1 |
| Butterworth, AE | 1 |
| Dalton, PR | 1 |
| Dunne, DW | 1 |
| Mugambi, M | 1 |
| Ouma, JH | 1 |
| Richardson, BA | 1 |
| Siongok, TK | 1 |
| Sturrock, RF | 1 |
| Barsoum, IS | 1 |
| Freeman, GL | 1 |
| Habib, M | 1 |
| El Alamy, MA | 1 |
| Rocha, RS | 1 |
| Katz, N | 6 |
| Gazzinelli, G | 1 |
| Colley, DG | 1 |
| Cioli, D | 1 |
| Chitsulo, L | 1 |
| Greco, DB | 2 |
| Pedroso, ER | 2 |
| da Costa Rocha, MO | 2 |
| Salazar, HM | 2 |
| de Lima, DP | 2 |
| Webbe, G | 3 |
| Wetsteyn, JC | 1 |
| van Lijf, JH | 1 |
| Stevens, WJ | 1 |
| Feldmeir, H | 1 |
| Bridts, CH | 1 |
| Daffalla, AA | 1 |
| Pehrson, PO | 1 |
| Bengtsson, E | 1 |
| Ott, BR | 1 |
| Libbey, NP | 1 |
| Ryter, RJ | 1 |
| Trebbin, WM | 1 |
| García Goyco, C | 1 |
| Torres Borges, A | 1 |
| Mitre, AI | 1 |
| Alfer Júnior, WU | 1 |
| Nahas, WC | 1 |
| Lopes, RN | 1 |
| Arap, S | 1 |
| Jordan, P | 5 |
| Unrau, GO | 1 |
| Bartholomew, RK | 4 |
| Cook, JA | 3 |
| Grist, E | 3 |
| Mahmoud, AA | 1 |
| Moyroud, J | 2 |
| Locheron, P | 1 |
| Cerf, P | 1 |
| Randrianarisoa, J | 1 |
| Coulanges, P | 1 |
| Auguste, E | 2 |
| Azevedo de Brito, P | 1 |
| Bickle, QD | 3 |
| de Lima e Costa, MF | 1 |
| Kilpatrick, ME | 3 |
| el-Masry, NA | 3 |
| Bassily, S | 6 |
| Farid, Z | 6 |
| Strickland, GT | 1 |
| Merritt, W | 1 |
| El-Sahly, A | 1 |
| Abdel-Wahab, F | 1 |
| Amin, SM | 1 |
| Habib, YA | 1 |
| Mikhail, AR | 1 |
| Hameid, LA | 1 |
| Disko, R | 1 |
| Mendes, E | 1 |
| Mendes, NF | 1 |
| Kohn, A | 1 |
| López-Alvarez, ML | 1 |
| El Masry, NA | 1 |
| Shenker, Y | 1 |
| Estrov, Z | 1 |
| Nussinson, E | 1 |
| Landau, Z | 1 |
| Resnitzky, P | 1 |
| de Souza Dias, LC | 1 |
| de Jesus Pedro, R | 1 |
| Deberaldini, ER | 1 |
| Kapend'a, K | 1 |
| Odio, W | 1 |
| Toko, AL | 1 |
| Vandepitte, J | 1 |
| Kayembe, NN | 1 |
| Wane, J | 1 |
| Mpamila, K | 1 |
| Manshande, JP | 1 |
| Gerold, JL | 1 |
| de Vries, H | 1 |
| Gryseels, B | 1 |
| Gilles, HM | 1 |
| Mikhail, EG | 1 |
| Sabet, S | 1 |
| Mahran, SG | 1 |
| Gaber, AA | 1 |
| Soliman, AA | 1 |
| Zaki, IE | 1 |
| Tadros, MB | 1 |
| Sleigh, AC | 2 |
| Mott, KE | 2 |
| Silva, JT | 1 |
| Muniz, TM | 1 |
| Mota, EA | 2 |
| Barreto, ML | 2 |
| Hoff, R | 2 |
| Maguire, JH | 3 |
| Lehman, JS | 1 |
| Sherlock, I | 2 |
| Trabolsi, B | 3 |
| Watten, RH | 4 |
| Gelfand, M | 2 |
| de V Clarke, V | 3 |
| Bernberg, H | 1 |
| Queinnec, J | 1 |
| de Souza, DW | 1 |
| Neves, J | 1 |
| Marinho, RP | 1 |
| Coelho, PM | 1 |
| de Lima Costa, MF | 1 |
| El-Zoghby, SM | 2 |
| Ebied, SA | 2 |
| Kholy, ZA | 1 |
| Saad, AA | 1 |
| Abdel-Tawab, GA | 1 |
| Doenhoff, M | 1 |
| Bickle, Q | 1 |
| Bain, J | 1 |
| Nelson, G | 1 |
| Ibrahim, AM | 1 |
| El-Toukhy, MA | 1 |
| Abd-Rabbo, H | 1 |
| Hamouda, N | 1 |
| El-Gohary, YA | 1 |
| Higashi, GI | 3 |
| Araujo, N | 1 |
| Pinto Dias, E | 1 |
| de Souza, CP | 1 |
| Lucey, DR | 1 |
| Charmot, G | 1 |
| Contigli, C | 1 |
| Carmo, SA | 1 |
| Goes, AM | 1 |
| Pieri, OS | 1 |
| Barbosa, CS | 1 |
| Moza, PG | 1 |
| Ripert, C | 1 |
| Mahmoud, KM | 1 |
| Sobh, MA | 1 |
| El-Agroudy, AE | 1 |
| Mostafa, FE | 1 |
| Baz, ME | 1 |
| Shokeir, AA | 1 |
| Ghoneim, MA | 1 |
| Alves, JG | 1 |
| Ulisses Montenegro, FM | 1 |
| Haese, WH | 1 |
| Bueding, E | 1 |
| Ramírez Ronda, CH | 1 |
| Guimarães, RX | 2 |
| Tchakerian, A | 1 |
| Dias, LC | 2 |
| de Almeida, FM | 2 |
| Vilela, MP | 2 |
| Cabeca, M | 2 |
| Takeda, AK | 1 |
| Pricoli, TI | 1 |
| Salem, N | 1 |
| Ferraz, CN | 1 |
| Arroyo, JB | 1 |
| Fukuda, Y | 1 |
| Geocze, S | 1 |
| Tancredi Neto, A | 1 |
| Pitchford, RJ | 1 |
| Lewis, M | 1 |
| Saif, M | 2 |
| Gaber, A | 3 |
| Hassanein, YS | 1 |
| Khameis, S | 1 |
| Eyakuze, VM | 1 |
| Rutasitara, WK | 1 |
| Ndalahwa, JB | 1 |
| Shafei, AZ | 2 |
| Pedro, RD | 1 |
| Amato Neto, V | 1 |
| De Carvalho, SA | 1 |
| Girgis, NI | 1 |
| Mansour, NS | 1 |
| Kahlil, SB | 1 |
| Gentilini, M | 1 |
| Danis, M | 1 |
| Richard-Lenoble, D | 1 |
| Brucker, G | 1 |
| de Alencar, JE | 1 |
| Rouquayrol, MZ | 1 |
| de Figueiredo, JS | 1 |
| Bezerra, OF | 1 |
| Ambroise-Thomas, P | 1 |
| Goullier, A | 1 |
| Bonneville, B | 1 |
| Couderc, P | 1 |
| El-Hawey, AM | 1 |
| Saber, MA | 1 |
| Abou-Taleb, S | 1 |
| Jewsbury, JM | 1 |
| Blair, DM | 3 |
| Omer, AH | 1 |
| Magzoub, M | 1 |
| Adam, SE | 1 |
| Abaza, HH | 1 |
| Hammouda, N | 1 |
| Rabbo, HA | 1 |
| Hatchuel, W | 1 |
| Pellegrino, J | 1 |
| Mello, RT | 1 |
| Koura, M | 1 |
| Abdel-Meguid, M | 1 |
| Zicker, F | 1 |
| Pereira, JP | 1 |
| Axton, JH | 1 |
| Garnett, PA | 2 |
| Monsalve, MV | 1 |
| Frota-Pessoa, O | 1 |
| Campos, AM | 1 |
| Sette, H | 2 |
| Weber, MC | 2 |
| Caetano da Silva, L | 1 |
| Fischer Chamone, DA | 1 |
| Saez-Alquezar, A | 1 |
| Rees, PH | 1 |
| Bowry, HN | 1 |
| Roberts, JM | 1 |
| Thuku, JJ | 1 |
| McMahon, JE | 1 |
| Vercruysse, J | 1 |
| Southgate, VR | 1 |
| Rollinson, D | 1 |
| Hilderson, H | 1 |
| Weller, TH | 1 |
| Davis, A | 1 |
| Massoud, AM | 1 |
| Ghoneem, M | 1 |
| Massoud, M | 1 |
| Archer, S | 1 |
| el-Rooby, A | 1 |
| Andrews, BJ | 1 |
| Chunge, CN | 1 |
| Kimani, RG | 1 |
| Gachihi, G | 1 |
| Mkoji, G | 1 |
| Kamau, T | 1 |
| Rashid, JR | 1 |
| Mastin, AJ | 1 |
| Wilson, RA | 1 |
13 reviews available for oxamniquine and Bilharziasis
| Article | Year |
|---|---|
Rational approach to drug discovery for human schistosomiasis.
Topics: Animals; Drug Discovery; Humans; Oxamniquine; Praziquantel; Schistosoma mansoni; Schistosomiasis | 2021 |
Schistosomiasis: Drugs used and treatment strategies.
Topics: Animals; Anthelmintics; Biomedical Research; Brazil; Child; Female; Humans; Neglected Diseases; Oxam | 2017 |
[Schistosomiasis].
Topics: Cross-Sectional Studies; Diagnosis, Differential; Drug Administration Schedule; Eosinophilia; Humans | 2017 |
Combination chemotherapy of schistosomiasis in laboratory studies and clinical trials.
Topics: Animals; Artemisinins; Clinical Trials as Topic; Drug Therapy, Combination; Humans; Oxamniquine; Pra | 2003 |
Drugs for the control of parasitic diseases: current status and development in schistosomiasis.
Topics: Animals; Drug Resistance; Humans; Oxamniquine; Praziquantel; Public Health; Schistosoma; Schistosomi | 2003 |
[Present status of the treatment of helminthiasis].
Topics: Albendazole; Anthelmintics; Benzimidazoles; Cestode Infections; Echinococcosis; Helminthiasis; Human | 1984 |
Human schistosomiasis and its management.
Topics: Animals; Humans; Hycanthone; Oxamniquine; Praziquantel; Schistosoma; Schistosomiasis; Trichlorfon | 1984 |
Schistosomiasis: clinical features and relevance to hematology.
Topics: Anemia; Animals; Blood Coagulation Disorders; Eosinophilia; Humans; Mice; Niridazole; Oxamniquine; P | 1982 |
Schistosomiasis.
Topics: Adult; Animals; Female; Hepatitis B; HIV Infections; Humans; Male; Neoplasms; Oxamniquine; Praziquan | 1993 |
Chemotherapy of Schistosomiasis mansoni.
Topics: Amphotericin B; Animals; Antimony; Chemosterilants; Drug Evaluation; Drug Evaluation, Preclinical; E | 1977 |
Recent advances in schistosomiasis.
Topics: Adolescent; Child; Humans; Oxamniquine; Parasite Egg Count; Praziquantel; Schistosomiasis; Serologic | 1986 |
The chemotherapy of schistosomiasis.
Topics: Animals; Chemical Phenomena; Chemistry; Diphenylamine; Humans; Hycanthone; Isothiocyanates; Niridazo | 1985 |
Management of hepatic schistosomiasis.
Topics: Acute Disease; Animals; Central Nervous System; Child; Chronic Disease; Colon; Diagnosis, Differenti | 1985 |
15 trials available for oxamniquine and Bilharziasis
| Article | Year |
|---|---|
Randomized comparative trials of single doses of the newer antischistosomal drugs at Mwanza, Tanzania. I. Praziquantel and oxamniquine for the treatment of schistosomiasis mansoni.
Topics: Adolescent; Child; Clinical Trials as Topic; Feces; Female; Humans; Isoquinolines; Male; Nitroquinol | 1984 |
Preliminary clinical trial of oral oxamniquine in the treatment of Schistosoma mansoni in Ethiopia.
Topics: Adolescent; Adult; Clinical Trials as Topic; Dose-Response Relationship, Drug; Ethiopia; Humans; Nit | 1984 |
Schistosoma mansoni treatment with oral oxamniquine in Zambia.
Topics: Administration, Oral; Adolescent; Adult; Child; Clinical Trials as Topic; Dose-Response Relationship | 1984 |
Oxamniquine dosage in Malawi.
Topics: Adolescent; Child; Humans; Nitroquinolines; Oxamniquine; Schistosoma mansoni; Schistosomiasis | 1984 |
A double blind trial with oxamniquine in chronic schistosomiasis mansoni.
Topics: Adolescent; Child; Chronic Disease; Clinical Trials as Topic; Double-Blind Method; Feces; Female; Hu | 1982 |
Presymptomatic schistosomal colonic polyposis.
Topics: Adolescent; Adult; Child; Colonic Neoplasms; Egypt; Humans; Intestinal Polyps; Niridazole; Oxamniqui | 1982 |
Oxamniquine versus niridazole for treatment of uncomplicated Schistosoma mansoni infection.
Topics: Adolescent; Adult; Animals; Child; Humans; Liver Diseases, Parasitic; Liver Function Tests; Male; Mi | 1982 |
Evaluation of oxamniquine in the treatment of S. mansoni infection among Sudanese patients.
Topics: Humans; Nitroquinolines; Oxamniquine; Schistosoma mansoni; Schistosomiasis | 1980 |
Schistosomiasis control based on repeated chemotherapy in a rural village of the sugar-cane zone in northeast Brazil.
Topics: Adolescent; Brazil; Child, Preschool; Drug Administration Schedule; Endemic Diseases; Health Surveys | 1998 |
Oxamniquine in the treatment of various schistosome infections in South Africa.
Topics: Adolescent; Child; Clinical Trials as Topic; Dose-Response Relationship, Drug; Humans; Nitroquinolin | 1978 |
Efficacy of oxamniquine in treatment of S. mansoni in a closed community in Egypt and the concomitant administration of both metrifonate and oxamniquine in mixed infections.
Topics: Adult; Clinical Trials as Topic; Drug Therapy, Combination; Egypt; Humans; Male; Nitroquinolines; Ox | 1978 |
A preliminary report on the treatment of intestinal schistosomiasis with oxamniquine.
Topics: Adolescent; Adult; Female; Humans; Intestinal Diseases, Parasitic; Male; Middle Aged; Nitroquinoline | 1979 |
Oxamniquine for treating Schistosoma mansoni infection in Sudan.
Topics: Adolescent; Adult; Child; Dose-Response Relationship, Drug; Feces; Female; Humans; Male; Middle Aged | 1978 |
Dose-finding trials of oral oxamniquine in Rhodesia.
Topics: Adolescent; Adult; Child; Child, Preschool; Drug Administration Schedule; Female; Humans; Male; Nitr | 1976 |
The treatment of schistosomiasis mansoni in Murang'a District, Kenya: a double blind controlled trial of three hycanthone regimens and oxamniquine.
Topics: Adolescent; Body Weight; Child; Dose-Response Relationship, Drug; Drug Evaluation; Female; Humans; H | 1975 |
106 other studies available for oxamniquine and Bilharziasis
| Article | Year |
|---|---|
Drug Discovery and Target Identification against Schistosomiasis: A Reality Check on Progress and Future Prospects.
Topics: Animals; Drug Discovery; Humans; Mice; Oxamniquine; Praziquantel; Schistosoma; Schistosomiasis | 2022 |
Disulfiram and dithiocarbamate analogues demonstrate promising antischistosomal effects.
Topics: Adult; Aldehyde Dehydrogenase; Animals; Disulfiram; Humans; Neglected Diseases; Nitrogen; Oxamniquin | 2022 |
Oxamniquine derivatives overcome Praziquantel treatment limitations for Schistosomiasis.
Topics: Animals; Anthelmintics; Combined Modality Therapy; Humans; Neglected Diseases; Oxamniquine; Praziqua | 2023 |
Molecular basis for hycanthone drug action in schistosome parasites.
Topics: Animals; Crystallization; Crystallography, X-Ray; Drug Design; Drug Resistance; Humans; Hycanthone; | 2020 |
An iterative process produces oxamniquine derivatives that kill the major species of schistosomes infecting humans.
Topics: Animals; Anthelmintics; Computer Simulation; Helminth Proteins; Humans; Models, Biological; Models, | 2020 |
Multidisciplinary Preclinical Investigations on Three Oxamniquine Analogues as New Drug Candidates for Schistosomiasis*.
Topics: Animals; Humans; Oxamniquine; Pharmaceutical Preparations; Schistosoma mansoni; Schistosomiasis; Sch | 2020 |
Assessment of tegumental damage to Schistosoma mansoni and S. haematobium after in vitro exposure to ferrocenyl, ruthenocenyl and benzyl derivatives of oxamniquine using scanning electron microscopy.
Topics: Animals; Female; Inhibitory Concentration 50; Mice; Microscopy, Electron, Scanning; Organometallic C | 2018 |
Schistosomal Sulfotransferase Interaction with Oxamniquine Involves Hybrid Mechanism of Induced-fit and Conformational Selection.
Topics: Animals; Humans; Molecular Docking Simulation; Molecular Dynamics Simulation; Oxamniquine; Prodrugs; | 2020 |
Independent origins of loss-of-function mutations conferring oxamniquine resistance in a Brazilian schistosome population.
Topics: Alleles; Animals; Brazil; Child; Child, Preschool; Drug Resistance; Exons; Feces; Gene Frequency; Ge | 2016 |
Ultrasound and clinical investigation of hepatosplenic schistosomiasis: evaluation of splenomegaly and liver fibrosis four years after mass chemotherapy with oxamniquine.
Topics: Adolescent; Adult; Alcoholism; Female; Humans; Liver Cirrhosis; Logistic Models; Male; Multivariate | 2006 |
Synergy of concurrent low dose oxamniquine and praziquantel in schistosomiasis.
Topics: Adolescent; Adult; Child; Drug Synergism; Drug Therapy, Combination; Female; Humans; Isoquinolines; | 1983 |
Spinal cord disease due to Schistosoma mansoni successfully treated with oxamniquine.
Topics: Adult; Female; Humans; Nitroquinolines; Oxamniquine; Schistosoma mansoni; Schistosomiasis; Spinal Co | 1984 |
Spinal cord disease due to Schistosoma mansoni successfully treated with oxamniquine.
Topics: Humans; Nitroquinolines; Oxamniquine; Schistosomiasis; Spinal Cord Diseases | 1984 |
Cost-effectiveness of different ways of controlling intestinal schistosomiasis: a case study.
Topics: Adolescent; Adult; Age Factors; Child; Child, Preschool; Communicable Disease Control; Cost-Benefit | 1984 |
Schistosoma mansoni: ultrastructure of adults from mice treated with oxamniquine.
Topics: Animals; Extracellular Space; Female; Genitalia, Female; Liver; Male; Mice; Microscopy, Electron; Mu | 1984 |
Pharmacokinetic studies on praziquantel and oxamniquine in intestinal schistosomiasis.
Topics: Adolescent; Humans; Intestinal Diseases, Parasitic; Isoquinolines; Kinetics; Male; Nitroquinolines; | 1984 |
Haematuria in experimental schistosomiasis mansoni.
Topics: Animals; Female; Hematuria; Male; Mice; Oxamniquine; Schistosoma mansoni; Schistosomiasis; Time Fact | 1983 |
Effect of chemotherapy on experimental pulmonary schistosomiasis.
Topics: Animals; Granuloma; Hycanthone; Liver; Lung; Lung Diseases, Parasitic; Male; Mice; Nitroquinolines; | 1983 |
Effect of oxamniquine on some biological features of schistosomiasis in white mice.
Topics: Animals; Female; Intestines; Liver; Male; Mice; Nitroquinolines; Oxamniquine; Schistosoma mansoni; S | 1983 |
Effect of oxamniquine and praziquantel on cell mediated immunity in intestinal bilharziasis.
Topics: Humans; Immunity, Cellular; Isoquinolines; Nitroquinolines; Oxamniquine; Praziquantel; Schistosoma m | 1983 |
Safety and toxicity of oxamniquine in the treatment of Schistosoma mansoni infections, with particular reference to electroencephalographic abnormalities.
Topics: Adolescent; Adult; Aged; Child; Drug Evaluation; Electroencephalography; Female; Humans; Male; Middl | 1983 |
[Treatment of 700 cases of bilharziasis with the new drugs oxamniquine, oltipraz, praziquantel].
Topics: Adolescent; Adult; Child; Child, Preschool; Humans; Isoquinolines; Middle Aged; Nitroquinolines; Oxa | 1983 |
The treatment of experimental schistosomiasis with a combination of oxamniquine and praziquantel.
Topics: Animals; Drug Combinations; Drug Synergism; Female; Isoquinolines; Mice; Mice, Inbred Strains; Nitro | 1983 |
Immunity after treatment of human schistosomiasis mansoni. I. Study design, pretreatment observations and the results of treatment.
Topics: Adolescent; Adult; Animals; Antibodies; Biomphalaria; Child; Child, Preschool; Enzyme-Linked Immunos | 1984 |
Evaluation of natural killer activity in human schistosomiasis.
Topics: Adolescent; Adult; Aged; Brazil; Child; Cytotoxicity, Immunologic; Egypt; Humans; Killer Cells, Natu | 1984 |
Reversibility of drug-induced regression in female Schistosoma mansoni upon pairing with male worms in vivo.
Topics: Animals; Female; Male; Mice; Muridae; Nitroquinolines; Oxamniquine; Reproduction; Schistosoma manson | 1984 |
The six diseases of WHO. Schistosomiasis: some advances.
Topics: Humans; Molluscacides; Oxamniquine; Praziquantel; Schistosomiasis; Snails; Trichlorfon | 1981 |
[A couple with fever and eosinophilia].
Topics: Adult; Eosinophilia; Female; Fever; Humans; Male; Oxamniquine; Parasite Egg Count; Schistosoma manso | 1983 |
IgG and IgE circulating immune complexes, total serum IgE and parasite related IgE in patients with mono- or mixed infection with Schistosoma mansoni and/or S. haematobium. Influence of therapy.
Topics: Adolescent; Adult; Antibody Specificity; Antigen-Antibody Complex; Antigens; Child; Cross Reactions; | 1983 |
Treatment of Eritrean schistosomiasis mansoni with oxamniquine.
Topics: Adult; Humans; Nitroquinolines; Oxamniquine; Schistosoma mansoni; Schistosomiasis | 1983 |
Treatment of schistosome-induced glomerulonephritis. A case report and review of the literature.
Topics: Adult; Glomerulonephritis; Humans; Male; Oxamniquine; Schistosoma mansoni; Schistosomiasis | 1983 |
[Schistosomiasis: clinical spectrum of the disease and response to oxamniquine treatment in chronic infections].
Topics: Adolescent; Adult; Child; Female; Humans; Intestinal Diseases, Parasitic; Liver Diseases, Parasitic; | 1982 |
[Vesical schistosomiasis mansoni simulating a tumor. Report of a case (author's transl)].
Topics: Adult; Diagnosis, Differential; Humans; Male; Oxamniquine; Parasite Egg Count; Radiography; Schistos | 1980 |
Value of individual household water supplies in the maintenance phase of a schistosomiasis control programme in Saint-Lucia, after chemotherapy.
Topics: Adolescent; Adult; Animals; Child; Child, Preschool; Humans; Infant; Middle Aged; Oxamniquine; Sanit | 1982 |
[Study of the reservoir of intestinal bilharziasis in Ampefy. Treatment of 159 children with oxamniquine].
Topics: Adolescent; Animals; Biomphalaria; Body Weight; Child; Child, Preschool; Disease Vectors; Female; Fl | 1981 |
Evaluation of chemotherapy in the control of Schistosoma mansoni in Marquis Valley, Saint Lucia. I. Results in humans.
Topics: Adolescent; Adult; Child; Child, Preschool; Emigration and Immigration; Evaluation Studies as Topic; | 1982 |
Curative chemotherapy and resistance to reinfection in murine schistosomiasis.
Topics: Animals; Eosinophils; Female; Granuloma; Hycanthone; Inflammation; Liver; Macrophages; Male; Mice; N | 1982 |
Studies on the relationship between the survival of Schistosoma mansoni larvae in mice and the degree of resistance produced.
Topics: Animals; Antigens, Surface; Female; Immunization; Larva; Male; Mice; Mice, Inbred CBA; Niridazole; O | 1982 |
Comparative study of Schistosoma mansoni strains isolated from patients with toxemic or intestinal forms of schistosomiasis.
Topics: Adolescent; Animals; Child; Feces; Female; Humans; Intestine, Large; Intestine, Small; Leukocyte Cou | 1982 |
Clinical characteristics and response to therapy in Egyptian children heavily infected with Schistosoma mansoni.
Topics: Adolescent; Anemia; Child; Egypt; Female; Hepatomegaly; Humans; Male; Nitroquinolines; Oxamniquine; | 1982 |
Effect of some new antibilharzial drugs on oxygen consumption of mouse diaphragm and liver homogenates in experimental bilharziasis.
Topics: Animals; Diaphragm; Liver; Male; Mice; Oxamniquine; Oxygen Consumption; Schistosoma mansoni; Schisto | 1982 |
[Schistosomiasis. Problems and successes].
Topics: Communicable Disease Control; Egypt; Humans; Molluscacides; Oxamniquine; Praziquantel; Schistosomias | 1982 |
High levels of IgE in patients with schistosomiasis mansoni. Quantitation of total and specific IgE and IgG.
Topics: Adolescent; Adult; Female; Humans; Immunoglobulin E; Immunoglobulin G; Male; Middle Aged; Oxamniquin | 1982 |
Transmission and scanning electron microscopical studies in the tegument of male Schistosoma mansoni after oxamniquine treatment.
Topics: Animals; Mice; Mice, Inbred Strains; Microscopy, Electron; Microscopy, Electron, Scanning; Nitroquin | 1982 |
[Schistosomiasis mansoni infestation treated with oxamnaquine].
Topics: Adult; Biopsy; Female; Humans; Nitroquinolines; Oxamniquine; Rectum; Schistosoma mansoni; Schistosom | 1982 |
Schistosoma mansoni: the survival and reproductive status of mature infections in mice treated with oxamniquine.
Topics: Animals; Female; Liver; Male; Mice; Nitroquinolines; Oxamniquine; Reproduction; Schistosoma mansoni; | 1982 |
Use of praziquantel in patients with schistosomiasis mansoni previously treated with oxamniquine and/or hycanthone: resistance of Schistosoma mansoni to schistosomicidal agents.
Topics: Adolescent; Adult; Animals; Child; Drug Resistance; Female; Humans; Hycanthone; Isoquinolines; Mice; | 1982 |
[Oxamniquine in the treatment of Schistosoma mansoni infection].
Topics: Adolescent; Adult; Child; Child, Preschool; Democratic Republic of the Congo; Female; Humans; Male; | 1982 |
On the distribution and control of schistosomiasis mansoni in Maniema, Zaire.
Topics: Adolescent; Adult; Child; Democratic Republic of the Congo; Humans; Middle Aged; Oxamniquine; Parasi | 1982 |
The treatment of schistosomiasis.
Topics: Humans; Hycanthone; Niridazole; Oxamniquine; Praziquantel; Schistosomiasis; Trichlorfon | 1981 |
Oxamniquine treatment in experimental schistosomiasis mansoni. Biological, morphological and pathological changes induced by divided doses.
Topics: Animals; Mice; Nitroquinolines; Oxamniquine; Schistosoma mansoni; Schistosomiasis | 1981 |
A three year follow-up of chemotherapy with oxamniquine in a Brazilian community with endemic schistosomiasis mansoni.
Topics: Adult; Brazil; Child; Feces; Follow-Up Studies; Humans; Nitroquinolines; Oxamniquine; Parasite Egg C | 1981 |
Treatment of schistosomiasis mansoni with oxamniquine--five years' experience.
Topics: Adolescent; Adult; Child; Colonic Neoplasms; Humans; Intestinal Polyps; Liver Diseases; Male; Middle | 1981 |
The use of steroids in the earlier hypersensitivity stage of schistosomiasis.
Topics: Adult; Granuloma; Humans; Hypersensitivity; Male; Nitroquinolines; Oxamniquine; Paraplegia; Predniso | 1981 |
[Efficacy of oxamniquine in Schistosoma mansoni bilharziasis in Madagascar in a hospital milieu].
Topics: Adult; Female; Humans; Male; Middle Aged; Nitroquinolines; Oxamniquine; Parasite Egg Count; Schistos | 1981 |
Therapeutic efficacy of oral oxamniquine in the toxemic form of schistosomiasis mansoni: treatment of eleven individuals from two families, and experimental study.
Topics: Adolescent; Animals; Brazil; Child; Feces; Female; Humans; Liver; Male; Nitroquinolines; Oxamniquine | 1980 |
Effect of oxamniquine on liver, spleen, kidney and bladder B-glucuronidase in normal and Schistosoma mansoni infected mice.
Topics: Animals; Glucuronidase; Kidney; Liver; Mice; Nitroquinolines; Oxamniquine; Schistosoma mansoni; Schi | 1980 |
Factors affecting the acquisition of resistance against Schistosoma mansoni in the mouse. V. Reduction in the degree of resistance to reinfection after chemotherapeutic elimination of recently patent primary infections.
Topics: Animals; Antimony Potassium Tartrate; Hycanthone; Immunity, Active; Mice; Mice, Inbred CBA; Niridazo | 1980 |
Effect of oxamniquine therapy on kynurenine metabolism in liver homogenates of normal and S. mansoni infected mice.
Topics: Animals; Biotransformation; In Vitro Techniques; Kynurenine; Liver; Mice; Nitroquinolines; ortho-Ami | 1980 |
Treatment of advanced hepatosplenic schistosomiasis with oxamniquine.
Topics: Adult; Child; Follow-Up Studies; Humans; Liver Diseases, Parasitic; Male; Middle Aged; Oxamniquine; | 1980 |
Susceptibility to chemotherapeutic agents of strains of Schistosoma mansoni isolated from treated and untreated patients.
Topics: Adolescent; Adult; Animals; Child; Female; Humans; Hycanthone; Male; Mice; Niridazole; Oxamniquine; | 1980 |
Schistosoma mansoni control in Cul de Sac Valley, Saint Lucia. II. Chemotherapy as a supplement to a focal mollusciciding programme.
Topics: Feces; Humans; Hycanthone; Molluscacides; Oxamniquine; Pest Control; Schistosoma mansoni; Schistosom | 1980 |
[Treatment of bilharziasis].
Topics: Humans; Mass Screening; Niridazole; Oxamniquine; Praziquantel; Schistosomiasis; Trichlorfon | 1993 |
Characterization of Schistosoma mansoni specific human T-T hybrids.
Topics: Animals; Antigens, Helminth; Cytokines; Granuloma; Humans; Hybridomas; Immunophenotyping; Interleuki | 1998 |
[Schistosomiasis: diagnosis and treatment].
Topics: Animals; Anthelmintics; Humans; Oxamniquine; Praziquantel; Prognosis; Schistosomiasis; Schistosomici | 2000 |
Impact of schistosomiasis on patient and graft outcome after renal transplantation: 10 years' follow-up.
Topics: Adult; Anthelmintics; Female; Follow-Up Studies; Humans; Kidney Failure, Chronic; Kidney Transplanta | 2001 |
Portal hypertension due to schistosomiasis.
Topics: Child, Preschool; Female; Humans; Hypertension, Portal; Liver Diseases, Parasitic; Oxamniquine; Schi | 2001 |
Long-term hepatocellular effects of hycanthone and of two other anti-Schistosomal drugs in mice infected with Schistosoma mansoni.
Topics: Animals; Carcinoma, Hepatocellular; Female; Hycanthone; Indazoles; Liver; Liver Neoplasms; Mice; Nit | 1976 |
Oxamniquine, bilharzia and Puerto Rico.
Topics: Forecasting; Humans; Nitroquinolines; Oxamniquine; Parasite Egg Count; Puerto Rico; Schistosomiasis | 1979 |
[Resistance to hycanthone and oxamniquine in patients with a clinical hepato-intestinal form of schistosomiasis].
Topics: Adult; Animals; Drug Resistance; Female; Humans; Hycanthone; Intestinal Diseases, Parasitic; Liver D | 1979 |
[Therapeutic evaluation of oxamniquine in schistosomiasis mansoni].
Topics: Humans; Nitroquinolines; Oxamniquine; Schistosoma mansoni; Schistosomiasis | 1979 |
Field use of oral oxamniquine in the treatment of S. mansoni.
Topics: Administration, Oral; Adolescent; Adult; Child; Humans; Middle Aged; Nitroquinolines; Oxamniquine; S | 1979 |
Observations on the treatment of mansoni schistosomiasis with oxamniquine.
Topics: Adolescent; Child; Child, Preschool; Feces; Female; Humans; Hycanthone; Liver; Male; Microscopy, Ele | 1979 |
Oxamniquine and fever.
Topics: Female; Fever; Humans; Nitroquinolines; Oxamniquine; Schistosoma mansoni; Schistosomiasis | 1979 |
Prophylactic-protective activity of oral oxamniquine against Schistosoma mansoni infection in hamsters.
Topics: Animals; Cricetinae; Nitroquinolines; Oxamniquine; Schistosoma mansoni; Schistosomiasis | 1979 |
Further experience on the use of oxamniquine in the treatment of advanced intestinal schistosomiasis.
Topics: Adolescent; Adult; Child; Humans; Male; Middle Aged; Nitroquinolines; Oxamniquine; Schistosoma manso | 1979 |
[Treatment of intestinal bilharziasis with oxamniquine. Preliminary results in 50 patients].
Topics: Humans; Nitroquinolines; Oxamniquine; Schistosomiasis | 1979 |
[Schistosomiasis in Ceará, analysis of the current problem and suggestions for its control].
Topics: Animals; Biomphalaria; Brazil; Disease Reservoirs; Disease Vectors; Humans; Molluscacides; Oxamniqui | 1978 |
[Schistosoma mansoni bilharziasis evolving 30 years after infestation].
Topics: Humans; Intestinal Diseases, Parasitic; Male; Middle Aged; Niridazole; Oxamniquine; Schistosoma mans | 1979 |
Studies on portal hypertension and its relation to serum histamine level in patients with bilharzial hepatic fibrosis.
Topics: Antimony Potassium Tartrate; Histamine; Humans; Hypertension, Portal; Liver; Liver Diseases, Parasit | 1978 |
Significant advances in the management of bilharziasis.
Topics: Humans; Nitroquinolines; Oxamniquine; Schistosomiasis; Trichlorfon | 1977 |
Oxamniquine in the prevention of bilharzial infection.
Topics: Animals; Cricetinae; Humans; Mice; Nitroquinolines; Oxamniquine; Schistosoma mansoni; Schistosomiasi | 1977 |
Oxamniquine (Vansil) in the treatment of Schistosoma mansoni infections in Rhodesia.
Topics: Child; Humans; Nitroquinolines; Oxamniquine; Schistosoma mansoni; Schistosomiasis; Zimbabwe | 1977 |
Treatment of bilharziasis due to Schistosoma haematobium infection.
Topics: Administration, Oral; Humans; Oxamniquine; Schistosoma haematobium; Schistosomiasis; Schistosomicide | 1977 |
Evaluation of oral therapy of mansonial schistosomiasis in the Sudan using single and multiple doses of hycanthone and oxamniquine drugs.
Topics: Animals; Drug Administration Schedule; Drug Therapy, Combination; Female; Hycanthone; Liver; Male; N | 1978 |
Treatment of complicated schistosomiasis mansoni with oxamniquine.
Topics: Adult; Child; Humans; Liver Diseases, Parasitic; Male; Middle Aged; Nitroquinolines; Oxamniquine; Sc | 1978 |
Chemotherapy of schistosomal colonic polyposis with oxamniquine.
Topics: Adult; Colonic Neoplasms; Female; Humans; Intestinal Diseases, Parasitic; Intestinal Polyps; Male; N | 1978 |
Fatal hepatic necrosis in association with hycanthone.
Topics: Chemical and Drug Induced Liver Injury; Humans; Hycanthone; Necrosis; Nitroquinolines; Oxamniquine; | 1978 |
Activity of known antischistosomal agents on early-developing forms of Schistosoma mansoni.
Topics: Animals; Antimony; Diethylamines; Edetic Acid; Hycanthone; Lithium; Lucanthone; Mice; Oxamniquine; S | 1975 |
Treatment of intestinal bilharziasis with oral oxamniquine (a preliminary report).
Topics: Administration, Oral; Animals; Cricetinae; Female; Haplorhini; Humans; Intestinal Diseases, Parasiti | 1975 |
Field trials with oxamniquine in a Schistosomiasis mansoni-endemic area.
Topics: Adolescent; Animals; Brazil; Child; Child, Preschool; Disease Reservoirs; Drug Tolerance; Headache; | 1977 |
Control of Schistosoma mansoni transmission by chemotherapy in St. Lucia. I. Results in man.
Topics: Adolescent; Adult; Child; Child, Preschool; Costs and Cost Analysis; Female; Humans; Hycanthone; Inf | 1977 |
A trial of oral oxamniquine in the treatment of Schistosoma infection in children.
Topics: Adolescent; Alanine Transaminase; Aspartate Aminotransferases; Child; Feces; Female; Humans; Male; N | 1976 |
A study of chromosomes of schistosomiasis patients under oxaminiquine (UK 4271) treatment.
Topics: Chromatids; Chromosomes; Humans; Lymphocytes; Nitroquinolines; Oxamniquine; Schistosoma mansoni; Sch | 1976 |
Oral oxamniquine in the treatment of persistent Schistosoma mansoni bilharziasis.
Topics: Administration, Oral; Adult; Drug Evaluation; Humans; Hydroxyquinolines; Male; Oxamniquine; Schistos | 1975 |
Letter: Clinical trials with oxamniquine in the treatment of human mansonian schistosomiasis.
Topics: Humans; Nitroquinolines; Oxamniquine; Schistosoma mansoni; Schistosomiasis | 1975 |
Oxamniquine (UK-4271) in Schistosoma haematobium infections.
Topics: Administration, Oral; Humans; Nitroquinolines; Oxamniquine; Schistosoma haematobium; Schistosomiasis | 1976 |
Experimental chemotherapy of Schistosoma curassoni in mice.
Topics: Animals; Disease Models, Animal; Female; Hycanthone; Male; Mice; Nitroquinolines; Oxamniquine; Prazi | 1989 |
Three-year prospective study of the evolution of Manson's schistosomiasis in north-east Brazil.
Topics: Adolescent; Adult; Brazil; Child; Child, Preschool; Cross-Sectional Studies; Hepatomegaly; Humans; O | 1985 |
Treatment of the acute (toxaemic) phase of schistosomiasis with oxamniquine.
Topics: Acute Disease; Humans; Nitroquinolines; Oxamniquine; Schistosomiasis | 1988 |
Treatment of schistosomiasis.
Topics: Humans; Nitroquinolines; Oxamniquine; Praziquantel; Schistosomiasis; Trichlorfon | 1987 |
The chemotherapy of schistosomiasis control.
Topics: Child; Humans; Oxamniquine; Praziquantel; Schistosomiasis; Schistosomicides; Trichlorfon | 1986 |
Effect of oxamniquine and praziquantel on intrasplenic pressure and portal vein diameter in hepatosplenic schistosomiasis.
Topics: Adult; Blood Pressure; Humans; Liver Diseases, Parasitic; Male; Nitroquinolines; Oxamniquine; Portal | 1986 |
Resistance following drug attenuation (Ro 11-3128 or oxamniquine) of early Schistosoma mansoni infections in mice.
Topics: Animals; Benzodiazepinones; Female; Mice; Mice, Inbred CBA; Nitroquinolines; Oxamniquine; Schistosom | 1985 |
Serious side effects of oxamniquine during the treatment of Schistosoma mansoni in Kenya.
Topics: Humans; Kenya; Nitroquinolines; Oxamniquine; Schistosoma mansoni; Schistosomiasis | 1985 |
Induction of resistance to Schistosoma mansoni in mice by chemotherapy: migration of schistosomula in primary and challenge infections.
Topics: Animals; Autoradiography; Benzodiazepinones; Female; Mice; Movement; Oxamniquine; Schistosoma manson | 1985 |