Page last updated: 2024-11-02

oxamniquine and Acute Disease

oxamniquine has been researched along with Acute Disease in 8 studies

Oxamniquine: An anthelmintic with schistosomicidal activity against Schistosoma mansoni, but not against other Schistosoma spp. Oxamniquine causes worms to shift from the mesenteric veins to the liver where the male worms are retained; the female worms return to the mesentery, but can no longer release eggs. (From Martindale, The Extra Pharmacopoeia, 31st ed, p121)
oxamniquine : A racemate comprising equimolar amounts of (R)- and (S)-oxamniquine. An anthelmintic, it is administered orally for the treatment of schistomiasis caused by Schistosoma mansoni (but not by other Schistosoma species); intramuscular administration is no longer used as it causes severe pain at the injection site.
{2-[(isopropylamino)methyl]-7-nitro-1,2,3,4-tetrahydroquinolin-6-yl}methanol : A member of the class of quinolines that is 1,2,3,4-tetrahydroquinoline which is substituted at positions 2, 6, and 7 by (isopropylamino)methyl, hydroxymethyl, and nitro groups, respectively.

Acute Disease: Disease having a short and relatively severe course.

Research Excerpts

ExcerptRelevanceReference
"The oxamniquine treatment of acute schistosomiasis patients is followed by an improvement of a Th1 response in vitro."1.34Treatment of human acute schistosomiasis with oxamniquine induces an increase in interferon-gamma response to Schistosoma mansoni antigens. ( Abath, FG; Aroucha, ML; Barbosa, CS; Carvalho Júnior, LB; de Souza, JR; Domingues, AL; Miranda, PJ; Montenegro, SM; Morais, CN, 2007)
"Schistosomiasis mansoni is a tropical parasitic disease caused by a blood fluke which inhabits the portal system of humans."1.29Scintigraphic findings in schistosomiasis. ( Orduña, E; Silva, F, 1995)

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19903 (37.50)18.7374
1990's1 (12.50)18.2507
2000's3 (37.50)29.6817
2010's1 (12.50)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Faria-Pinto, Pd1
Montesano, MA1
Jacinto, AA1
Santos, RS1
Bordin, FH1
Ferreira, AP1
Penido, ML1
Coelho, PM2
Vasconcelos, EG1
Enk, MJ1
Amorim, A1
Schall, VT1
Carvalho, MG1
Mello, RT1
Soares, AL1
Bicalho, RS1
Lima e Silva, FC1
de Souza, JR1
Morais, CN1
Aroucha, ML1
Miranda, PJ1
Barbosa, CS1
Domingues, AL1
Carvalho Júnior, LB1
Abath, FG1
Montenegro, SM1
Orduña, E1
Silva, F1
Lambertucci, JR2
el-Rooby, A1

Reviews

1 review available for oxamniquine and Acute Disease

ArticleYear
Management of hepatic schistosomiasis.
    Seminars in liver disease, 1985, Volume: 5, Issue:3

    Topics: Acute Disease; Animals; Central Nervous System; Child; Chronic Disease; Colon; Diagnosis, Differenti

1985

Other Studies

7 other studies available for oxamniquine and Acute Disease

ArticleYear
Antibody reactivity against potato apyrase, a protein that shares epitopes with Schistosoma mansoni ATP diphosphohydrolase isoforms, in acute and chronically infected mice, after chemotherapy and reinfection.
    Memorias do Instituto Oswaldo Cruz, 2010, Volume: 105, Issue:4

    Topics: Acute Disease; Animals; Anthelmintics; Antibodies, Helminth; Antigens, Helminth; Apyrase; Chronic Di

2010
Acute schistosomiasis outbreak in the metropolitan area of Belo Horizonte, Minas Gerais: alert about the risk of unnoticed transmission increased by growing rural tourism.
    Memorias do Instituto Oswaldo Cruz, 2003, Volume: 98, Issue:6

    Topics: Acute Disease; Animals; Biomphalaria; Brazil; Disease Outbreaks; Feces; Female; Health Knowledge, At

2003
Murine schistosomiasis mansoni: process of blood coagulation at pre-patent, acute and chronic phases, and consequence of chemotherapeutic cure on the reversion of changes.
    Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis, 2005, Volume: 16, Issue:7

    Topics: Acute Disease; Animals; Blood Coagulation; Blood Coagulation Factors; Chronic Disease; Female; Mice;

2005
Treatment of human acute schistosomiasis with oxamniquine induces an increase in interferon-gamma response to Schistosoma mansoni antigens.
    Memorias do Instituto Oswaldo Cruz, 2007, Volume: 102, Issue:2

    Topics: Acute Disease; Adolescent; Adult; Animals; Antibodies, Helminth; Antigens, Helminth; Child; Disease

2007
Scintigraphic findings in schistosomiasis.
    Puerto Rico health sciences journal, 1995, Volume: 14, Issue:4

    Topics: Acute Disease; Adolescent; Child; Follow-Up Studies; Hepatomegaly; Humans; Liver Function Tests; Mal

1995
A new approach to the treatment of acute schistosomiasis.
    Memorias do Instituto Oswaldo Cruz, 1989, Volume: 84 Suppl 1

    Topics: Acute Disease; Adolescent; Adult; Animals; Child; Child, Preschool; Dexamethasone; Drug Synergism; D

1989
Treatment of the acute (toxaemic) phase of schistosomiasis with oxamniquine.
    Transactions of the Royal Society of Tropical Medicine and Hygiene, 1988, Volume: 82, Issue:2

    Topics: Acute Disease; Humans; Nitroquinolines; Oxamniquine; Schistosomiasis

1988