oxamniquine has been researched along with Abnormalities, Autosome in 2 studies
Oxamniquine: An anthelmintic with schistosomicidal activity against Schistosoma mansoni, but not against other Schistosoma spp. Oxamniquine causes worms to shift from the mesenteric veins to the liver where the male worms are retained; the female worms return to the mesentery, but can no longer release eggs. (From Martindale, The Extra Pharmacopoeia, 31st ed, p121)
oxamniquine : A racemate comprising equimolar amounts of (R)- and (S)-oxamniquine. An anthelmintic, it is administered orally for the treatment of schistomiasis caused by Schistosoma mansoni (but not by other Schistosoma species); intramuscular administration is no longer used as it causes severe pain at the injection site.
{2-[(isopropylamino)methyl]-7-nitro-1,2,3,4-tetrahydroquinolin-6-yl}methanol : A member of the class of quinolines that is 1,2,3,4-tetrahydroquinoline which is substituted at positions 2, 6, and 7 by (isopropylamino)methyl, hydroxymethyl, and nitro groups, respectively.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Gross chromosomal aberrations were assessed in human leucocyte cultures and in bone marrow preparations from drug-treated mice." | 1.25 | A comparative study on the genetic effects of hycanthone and oxamniquine. ( Ellis, JH; Holden, HE; Hyneck, ML; Ray, VA, 1975) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ong, TM | 1 |
| Ray, VA | 1 |
| Holden, HE | 1 |
| Ellis, JH | 1 |
| Hyneck, ML | 1 |
1 review available for oxamniquine and Abnormalities, Autosome
| Article | Year |
|---|---|
Genetic activities of hycanthone and some other antischistosomal drugs.
Topics: Acrylamides; Animals; Carcinogens; Chromosome Aberrations; Chromosomes; Drosophila; Genes, Dominant; | 1978 |
1 other study available for oxamniquine and Abnormalities, Autosome
| Article | Year |
|---|---|
A comparative study on the genetic effects of hycanthone and oxamniquine.
Topics: Animals; Biological Assay; Bone Marrow; Bone Marrow Cells; Cells, Cultured; Chromosome Aberrations; | 1975 |