Page last updated: 2024-10-19

oxamic acid and Neoplasms

oxamic acid has been researched along with Neoplasms in 4 studies

Oxamic Acid: Amino-substituted glyoxylic acid derivative.
oxamic acid : A dicarboxylic acid monoamide resulting from the formal condensation of one of the carboxy groups of oxalic acid with ammonia.

Neoplasms: New abnormal growth of tissue. Malignant neoplasms show a greater degree of anaplasia and have the properties of invasion and metastasis, compared to benign neoplasms.

Research Excerpts

ExcerptRelevanceReference
"Cancer is one of the main causes of human mortality and brain tumors, including invasive pituitary adenomas, medulloblastomas and glioblastomas are common brain malignancies with poor prognosis."2.82Oxamate targeting aggressive cancers with special emphasis to brain tumors. ( Altinoz, MA; Ozpinar, A, 2022)
"Kinetic modeling of cancer glycolysis revealed that oxamate inhibition of LDH, PYK and ENO was insufficient to achieve glycolysis flux inhibition."1.46Assessment of the low inhibitory specificity of oxamate, aminooxyacetate and dichloroacetate on cancer energy metabolism. ( Del Mazo-Monsalvo, I; Marín-Hernández, Á; Moreno-Sánchez, R; Rodríguez-Enríquez, S; Saavedra, E, 2017)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19901 (25.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's2 (50.00)24.3611
2020's1 (25.00)2.80

Authors

AuthorsStudies
Rani, R1
Kumar, V1
Altinoz, MA1
Ozpinar, A1
Moreno-Sánchez, R1
Marín-Hernández, Á1
Del Mazo-Monsalvo, I1
Saavedra, E1
Rodríguez-Enríquez, S1
PAPACONSTANTINOU, J1
COLOWICK, SP1

Reviews

2 reviews available for oxamic acid and Neoplasms

ArticleYear
Recent Update on Human Lactate Dehydrogenase Enzyme 5 (hLDH5) Inhibitors: A Promising Approach for Cancer Chemotherapy.
    Journal of medicinal chemistry, 2016, Jan-28, Volume: 59, Issue:2

    Topics: Antineoplastic Agents; Drug Design; Enzyme Inhibitors; Humans; Isoenzymes; L-Lactate Dehydrogenase;

2016
Oxamate targeting aggressive cancers with special emphasis to brain tumors.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2022, Volume: 147

    Topics: Animals; Brain Neoplasms; Cell Line, Tumor; Glycolysis; Humans; L-Lactate Dehydrogenase; Mitochondri

2022

Other Studies

2 other studies available for oxamic acid and Neoplasms

ArticleYear
Assessment of the low inhibitory specificity of oxamate, aminooxyacetate and dichloroacetate on cancer energy metabolism.
    Biochimica et biophysica acta. General subjects, 2017, Volume: 1861, Issue:1 Pt A

    Topics: Aminooxyacetic Acid; Animals; Antineoplastic Agents; Cell Line, Tumor; Computer Simulation; Dichloro

2017
The role of glycolysis in the growth of tumor cells. I. Effects of oxamic acid on the metabolism of Ehrlich ascites tumor cells in vitro.
    The Journal of biological chemistry, 1961, Volume: 236

    Topics: Animals; Carbohydrate Metabolism; Carbohydrates; Carcinoma, Ehrlich Tumor; Diploidy; Glycolysis; In

1961