oxamic acid has been researched along with Neoplasms in 4 studies
Oxamic Acid: Amino-substituted glyoxylic acid derivative.
oxamic acid : A dicarboxylic acid monoamide resulting from the formal condensation of one of the carboxy groups of oxalic acid with ammonia.
Neoplasms: New abnormal growth of tissue. Malignant neoplasms show a greater degree of anaplasia and have the properties of invasion and metastasis, compared to benign neoplasms.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Cancer is one of the main causes of human mortality and brain tumors, including invasive pituitary adenomas, medulloblastomas and glioblastomas are common brain malignancies with poor prognosis." | 2.82 | Oxamate targeting aggressive cancers with special emphasis to brain tumors. ( Altinoz, MA; Ozpinar, A, 2022) |
| "Kinetic modeling of cancer glycolysis revealed that oxamate inhibition of LDH, PYK and ENO was insufficient to achieve glycolysis flux inhibition." | 1.46 | Assessment of the low inhibitory specificity of oxamate, aminooxyacetate and dichloroacetate on cancer energy metabolism. ( Del Mazo-Monsalvo, I; Marín-Hernández, Á; Moreno-Sánchez, R; Rodríguez-Enríquez, S; Saavedra, E, 2017) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (25.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (50.00) | 24.3611 |
| 2020's | 1 (25.00) | 2.80 |
| Authors | Studies |
|---|---|
| Rani, R | 1 |
| Kumar, V | 1 |
| Altinoz, MA | 1 |
| Ozpinar, A | 1 |
| Moreno-Sánchez, R | 1 |
| Marín-Hernández, Á | 1 |
| Del Mazo-Monsalvo, I | 1 |
| Saavedra, E | 1 |
| Rodríguez-Enríquez, S | 1 |
| PAPACONSTANTINOU, J | 1 |
| COLOWICK, SP | 1 |
2 reviews available for oxamic acid and Neoplasms
| Article | Year |
|---|---|
Recent Update on Human Lactate Dehydrogenase Enzyme 5 (hLDH5) Inhibitors: A Promising Approach for Cancer Chemotherapy.
Topics: Antineoplastic Agents; Drug Design; Enzyme Inhibitors; Humans; Isoenzymes; L-Lactate Dehydrogenase; | 2016 |
Oxamate targeting aggressive cancers with special emphasis to brain tumors.
Topics: Animals; Brain Neoplasms; Cell Line, Tumor; Glycolysis; Humans; L-Lactate Dehydrogenase; Mitochondri | 2022 |
2 other studies available for oxamic acid and Neoplasms
| Article | Year |
|---|---|
Assessment of the low inhibitory specificity of oxamate, aminooxyacetate and dichloroacetate on cancer energy metabolism.
Topics: Aminooxyacetic Acid; Animals; Antineoplastic Agents; Cell Line, Tumor; Computer Simulation; Dichloro | 2017 |
The role of glycolysis in the growth of tumor cells. I. Effects of oxamic acid on the metabolism of Ehrlich ascites tumor cells in vitro.
Topics: Animals; Carbohydrate Metabolism; Carbohydrates; Carcinoma, Ehrlich Tumor; Diploidy; Glycolysis; In | 1961 |