oxamic acid has been researched along with Hepatocellular Carcinoma in 5 studies
Oxamic Acid: Amino-substituted glyoxylic acid derivative.
oxamic acid : A dicarboxylic acid monoamide resulting from the formal condensation of one of the carboxy groups of oxalic acid with ammonia.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Using oxamic acid, an inhibitor of lactic dehydrogenase (LDH) which hinders aerobic glycolysis, we decreased ATP levels in PLC/PRF/5 cells (a line from a hepatocellular carcinoma)." | 3.77 | Inhibition of lactic dehydrogenase as a way to increase the anti-proliferative effect of multi-targeted kinase inhibitors. ( Di Stefano, G; Fiume, L; Manerba, M; Vettraino, M, 2011) |
| " Here, we studied the effect of oxamic and tartronic acids, 2 inhibitors of LDH, on aerobic glycolysis and cell replication of HepG2 and PLC/PRF/5 cells, 2 lines from human hepatocellular carcinomas." | 3.76 | Impairment of aerobic glycolysis by inhibitors of lactic dehydrogenase hinders the growth of human hepatocellular carcinoma cell lines. ( Di Stefano, G; Fiume, L; Manerba, M; Vettraino, M, 2010) |
| "Hepatocellular carcinoma is one of the conditions in which HSR activation was shown to have the highest clinical significance." | 1.46 | LDH inhibition impacts on heat shock response and induces senescence of hepatocellular carcinoma cells. ( Di Ianni, L; Di Stefano, G; Govoni, M; Manerba, M; Recanatini, M; Roberti, M, 2017) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (20.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 4 (80.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Manerba, M | 3 |
| Di Ianni, L | 1 |
| Govoni, M | 1 |
| Roberti, M | 1 |
| Recanatini, M | 1 |
| Di Stefano, G | 3 |
| Fiume, L | 3 |
| Vettraino, M | 2 |
| Li, XW | 1 |
| Li, XJ | 1 |
| Li, YT | 1 |
| Wu, ZY | 1 |
| Yan, CW | 1 |
5 other studies available for oxamic acid and Hepatocellular Carcinoma
| Article | Year |
|---|---|
LDH inhibition impacts on heat shock response and induces senescence of hepatocellular carcinoma cells.
Topics: Adenosine Triphosphatases; alpha-Fetoproteins; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Sur | 2017 |
Impairment of aerobic glycolysis by inhibitors of lactic dehydrogenase hinders the growth of human hepatocellular carcinoma cell lines.
Topics: Adenosine Triphosphate; Antineoplastic Agents; Apoptosis; Apoptosis Regulatory Proteins; Carcinoma, | 2010 |
Inhibition of lactic dehydrogenase as a way to increase the anti-proliferative effect of multi-targeted kinase inhibitors.
Topics: Adenosine Triphosphate; Antineoplastic Agents; Benzenesulfonates; Carcinoma, Hepatocellular; Cell Li | 2011 |
Syntheses and structures of new trimetallic complexes bridged by N-(5-chloro-2-hydroxyphenyl)-N'-[3-(dimethylamino)propyl]oxamide: cytotoxic activities, and reactivities towards DNA and protein.
Topics: Adenocarcinoma; Adenocarcinoma of Lung; Antineoplastic Agents; Carcinoma, Hepatocellular; Cell Line, | 2013 |
[Effect of inhibition of lactic dehydrogenase by the action of oxamic acid on the development of Yoshida's ascites hepatoma].
Topics: Acids; Animals; Ascites; Carcinoma, Hepatocellular; Liver Neoplasms; Neoplasms, Experimental; Oxamic | 1959 |