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oxamic acid and Asthma, Bronchial

oxamic acid has been researched along with Asthma, Bronchial in 12 studies

Oxamic Acid: Amino-substituted glyoxylic acid derivative.
oxamic acid : A dicarboxylic acid monoamide resulting from the formal condensation of one of the carboxy groups of oxalic acid with ammonia.

Research Excerpts

ExcerptRelevanceReference
"The inhibition of immediate allergen-induced airflow obstruction by lodoxamide tromethamine (LT), a new drug with properties considered to be similar to those of sodium cromoglycate, was studied in twelve young asthmatic volunteers."9.05The effect of lodoxamide tromethamine on the immediate asthmatic response to allergen provocation. ( Bentley, S; Davies, RJ; Graham, VA; Ollier, S, 1982)
"Lodoxamide tromethamine, a new cromolyn-like drug, was studied to determine its effectiveness and duration of action in preventing antigen-induced bronchospasm in 15 subjects with clinically stable extrinsic asthma."9.05Effect of inhaled iodoxamide tromethamine in prevention of antigen-induced bronchospasm. ( Deutsch, RI; Siegel, SC; Tashkin, DP; Ungerer, RG, 1981)
"The efficacy of lodoxamide tromethamine in the treatment of asthma was studied in a 16-week double-blind, placebo-controlled study of 68 perennial allergic subjects with asthma."9.05Inhaled lodoxamide tromethamine in the treatment of perennial asthma: a double-blind placebo-controlled study. ( Clement, P; Fairfax, AJ; Holgate, ST; Mann, JS; Sheridan, AQ; Soryal, I, 1985)
"We monitored 14 asthmatic subjects (aged 18 to 60 years), with multiple 24-hour electrocardiogram (Holter) recordings, who were taking continuous sustained-release theophylline and beta-2-adrenergic therapy for control of their symptoms."7.67Lack of significant arrhythmogenicity from chronic theophylline and beta-2-adrenergic combination therapy in asthmatic subjects. ( Kelly, HW; Menendez, R; Voyles, W, 1985)
"The inhibition of immediate allergen-induced airflow obstruction by lodoxamide tromethamine (LT), a new drug with properties considered to be similar to those of sodium cromoglycate, was studied in twelve young asthmatic volunteers."5.05The effect of lodoxamide tromethamine on the immediate asthmatic response to allergen provocation. ( Bentley, S; Davies, RJ; Graham, VA; Ollier, S, 1982)
"Lodoxamide tromethamine, a new cromolyn-like drug, was studied to determine its effectiveness and duration of action in preventing antigen-induced bronchospasm in 15 subjects with clinically stable extrinsic asthma."5.05Effect of inhaled iodoxamide tromethamine in prevention of antigen-induced bronchospasm. ( Deutsch, RI; Siegel, SC; Tashkin, DP; Ungerer, RG, 1981)
"The efficacy of lodoxamide tromethamine in the treatment of asthma was studied in a 16-week double-blind, placebo-controlled study of 68 perennial allergic subjects with asthma."5.05Inhaled lodoxamide tromethamine in the treatment of perennial asthma: a double-blind placebo-controlled study. ( Clement, P; Fairfax, AJ; Holgate, ST; Mann, JS; Sheridan, AQ; Soryal, I, 1985)
"We monitored 14 asthmatic subjects (aged 18 to 60 years), with multiple 24-hour electrocardiogram (Holter) recordings, who were taking continuous sustained-release theophylline and beta-2-adrenergic therapy for control of their symptoms."3.67Lack of significant arrhythmogenicity from chronic theophylline and beta-2-adrenergic combination therapy in asthmatic subjects. ( Kelly, HW; Menendez, R; Voyles, W, 1985)
"A most active biologue of disodium cromoglycate (DSCG) available, lodoxamide tromethamine (LT), has been studied and characterized pharmacologically, in animal and human models of asthma."3.67The characterization of lodoxamide, a very active inhibitor of mediator release, in animal and human models of asthma. ( Johnson, HG; Sheridan, AQ, 1986)
"Lodoxamide tromethamine (U-42,585E) is a new drug intended for prophylaxis of mast cell-mediated allergic disease."2.65Protective effect opf lodoxamide tromethamine on allergen inhalation challenge. ( Bewtra, AK; Bui, TC; Townley, RG; Watt, GD, 1980)

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-199011 (91.67)18.7374
1990's1 (8.33)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Parrish, RW1
Davies, BH1
Case, RL1
Rogers, PB1
VanArsdel, PP1
Altman, LC1
Ollier, S1
Graham, VA1
Bentley, S1
Davies, RJ1
Ungerer, RG1
Tashkin, DP1
Siegel, SC3
Deutsch, RI1
Watt, GD1
Bui, TC1
Bewtra, AK1
Townley, RG1
Mawhinney, H2
Spector, SL2
Kinsman, RA1
Rachelefsky, GS2
Katz, RM2
Rohr, AS2
Lewis, AJ2
Carlson, RP1
Forster, TJ1
Chang, J1
Hand, JM1
Undem, BJ1
Buckner, CK1
Tio, C1
Sisenwine, SF1
Daniel, WC1
Kelly, HW1
Menendez, R1
Voyles, W1
Johnson, HG1
Sheridan, AQ2
Kinsman, R1
Mann, JS1
Clement, P1
Soryal, I1
Fairfax, AJ1
Holgate, ST1

Reviews

1 review available for oxamic acid and Asthma, Bronchial

ArticleYear
Do anti-allergic drugs or anticholinergic drugs have a role in the treatment of asthma?
    Agents and actions. Supplements, 1988, Volume: 23

    Topics: Animals; Asthma; Bronchodilator Agents; Cromolyn Sodium; Humans; Mast Cells; Oxamic Acid; Parasympat

1988

Trials

8 trials available for oxamic acid and Asthma, Bronchial

ArticleYear
Inhalation challenge with specific grass pollen antigens in asthmatics and the effect of lodoxamide tromethamine.
    Thorax, 1983, Volume: 38, Issue:6

    Topics: Adult; Amino Acids; Asthma; Bronchial Provocation Tests; Clinical Trials as Topic; Double-Blind Meth

1983
The protective effect of lodoxamide on antigen-induced bronchospasm. An orally active antiallergic drug.
    JAMA, 1982, Feb-05, Volume: 247, Issue:5

    Topics: Administration, Oral; Adult; Amino Acids; Asthma; Bronchial Provocation Tests; Bronchial Spasm; Clin

1982
The effect of lodoxamide tromethamine on the immediate asthmatic response to allergen provocation.
    Clinical allergy, 1982, Volume: 12, Issue:6

    Topics: Administration, Intranasal; Adult; Allergens; Amino Acids; Asthma; Bronchial Provocation Tests; Dose

1982
Effect of inhaled iodoxamide tromethamine in prevention of antigen-induced bronchospasm.
    The Journal of allergy and clinical immunology, 1981, Volume: 68, Issue:6

    Topics: Adolescent; Adult; Amino Acids; Antigens; Asthma; Bronchial Spasm; Dose-Response Relationship, Immun

1981
Protective effect opf lodoxamide tromethamine on allergen inhalation challenge.
    The Journal of allergy and clinical immunology, 1980, Volume: 66, Issue:4

    Topics: Adolescent; Adult; Amino Acids; Analysis of Variance; Asthma; Bronchial Provocation Tests; Forced Ex

1980
Compliance in clinical trials of two nonbronchodilator, antiasthma medications.
    Annals of allergy, 1991, Volume: 66, Issue:4

    Topics: Administration, Inhalation; Adolescent; Adult; Aged; Anti-Inflammatory Agents; Asthma; Bronchi; Dose

1991
Compliance of patients with asthma with an experimental aerosolized medication: implications for controlled clinical trials.
    The Journal of allergy and clinical immunology, 1986, Volume: 77, Issue:1 Pt 1

    Topics: Adolescent; Adult; Aerosols; Aged; Amino Acids; Asthma; Clinical Trials as Topic; Female; Humans; Ma

1986
Inhaled lodoxamide tromethamine in the treatment of perennial asthma: a double-blind placebo-controlled study.
    The Journal of allergy and clinical immunology, 1985, Volume: 76, Issue:1

    Topics: Adolescent; Adult; Aerosols; Amino Acids; Asthma; Chronic Disease; Double-Blind Method; Female; Huma

1985

Other Studies

3 other studies available for oxamic acid and Asthma, Bronchial

ArticleYear
The development of Wy-41,195, an orally effective antiallergic drug in animal models.
    Agents and actions, 1986, Volume: 18, Issue:3-4

    Topics: Administration, Oral; Amino Acids; Animals; Asthma; Disease Models, Animal; Dogs; Guinea Pigs; Hista

1986
Lack of significant arrhythmogenicity from chronic theophylline and beta-2-adrenergic combination therapy in asthmatic subjects.
    Annals of allergy, 1985, Volume: 54, Issue:5

    Topics: Adolescent; Adrenergic beta-Agonists; Adult; Aged; Arrhythmias, Cardiac; Asthma; Atrial Function; De

1985
The characterization of lodoxamide, a very active inhibitor of mediator release, in animal and human models of asthma.
    Agents and actions, 1986, Volume: 18, Issue:3-4

    Topics: Amino Acids; Animals; Asthma; Calcium; Cromolyn Sodium; Disease Models, Animal; Drug Evaluation; His

1986