oxalomalic-acid and Skin-Neoplasms

oxalomalic-acid has been researched along with Skin-Neoplasms* in 1 studies

Other Studies

1 other study(ies) available for oxalomalic-acid and Skin-Neoplasms

ArticleYear
Oxalomalate reduces tumor progression in melanoma via ROS-dependent proapoptotic and antiangiogenic effects.
    Biochimie, 2019, Volume: 158

    The potent cytotoxicity of reactive oxygen species (ROS) can cause various diseases, however, it may also serve as a powerful chemotherapeutic strategy capable of killing cancer cells. Oxalomalate (OMA, α-hydroxy-β-oxalosuccinic acid), a tricarboxylic acid intermediate, is a well-known competitive inhibitor of two classes of NADP

    Topics: Angiogenesis Inhibitors; Animals; Apoptosis; Ataxia Telangiectasia Mutated Proteins; Cell Line, Tumor; Checkpoint Kinase 2; Isocitrate Dehydrogenase; Male; Melanoma; Mice; Neovascularization, Pathologic; Oxalates; Reactive Oxygen Species; Skin Neoplasms; Tumor Suppressor Protein p53

2019