Page last updated: 2024-10-19

oxaloacetic acid and Neurocysticercosis

oxaloacetic acid has been researched along with Neurocysticercosis in 2 studies

Oxaloacetic Acid: A dicarboxylic acid ketone that is an important metabolic intermediate of the CITRIC ACID CYCLE. It can be converted to ASPARTIC ACID by ASPARTATE TRANSAMINASE.
oxaloacetic acid : An oxodicarboxylic acid that is succinic acid bearing a single oxo group.

Neurocysticercosis: Infection of the brain, spinal cord, or perimeningeal structures with the larval forms of the genus TAENIA (primarily T. solium in humans). Lesions formed by the organism are referred to as cysticerci. The infection may be subacute or chronic, and the severity of symptoms depends on the severity of the host immune response and the location and number of lesions. SEIZURES represent the most common clinical manifestation although focal neurologic deficits may occur. (From Joynt, Clinical Neurology, 1998, Ch27, pp46-50)

Research Excerpts

ExcerptRelevanceReference
"Nitazoxanide (NTZ) is an antifolate containing the pyrrolopyrimidine-based nucleus that exerts its antiprotozoal activity due to interference with the pyruvate:ferredoxin oxidoreductase (PFOR) enzyme which is essential to anaerobic energy metabolism."5.51Oral nitazoxanide treatment of experimental neurocysticercosis induces gluconeogenesis in Taenia crassiceps cysticerci. ( Alves, DSMM; Costa, TL; Isac, E; Lima, NF; Lino Junior, RS; Picanço, GA; Silva, LD; Vinaud, MC, 2019)
"Nitazoxanide (NTZ) is a broad-spectrum drug used in intestinal infections, but still poorly explored in the treatment of parasitic tissular infections."1.56In vitro nitazoxanide exposure affects energetic metabolism of Taenia crassiceps. ( Alves, DSMM; Costa, TL; Fraga, CM; Isac, E; Lima, NF; Lino Junior, RS; Picanço, GA; Vinaud, MC, 2020)
"Nitazoxanide (NTZ) is an antifolate containing the pyrrolopyrimidine-based nucleus that exerts its antiprotozoal activity due to interference with the pyruvate:ferredoxin oxidoreductase (PFOR) enzyme which is essential to anaerobic energy metabolism."1.51Oral nitazoxanide treatment of experimental neurocysticercosis induces gluconeogenesis in Taenia crassiceps cysticerci. ( Alves, DSMM; Costa, TL; Isac, E; Lima, NF; Lino Junior, RS; Picanço, GA; Silva, LD; Vinaud, MC, 2019)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (50.00)24.3611
2020's1 (50.00)2.80

Authors

AuthorsStudies
Isac, E2
Picanço, GA2
Costa, TL2
Lima, NF2
Alves, DSMM2
Fraga, CM1
Lino Junior, RS2
Vinaud, MC2
Silva, LD1

Other Studies

2 other studies available for oxaloacetic acid and Neurocysticercosis

ArticleYear
In vitro nitazoxanide exposure affects energetic metabolism of Taenia crassiceps.
    Experimental parasitology, 2020, Volume: 208

    Topics: Albendazole; Analysis of Variance; Animals; Anthelmintics; Antiparasitic Agents; Citrates; Citric Ac

2020
Oral nitazoxanide treatment of experimental neurocysticercosis induces gluconeogenesis in Taenia crassiceps cysticerci.
    Acta tropica, 2019, Volume: 190

    Topics: Administration, Oral; Animals; Anthelmintics; Chromatography, High Pressure Liquid; Cysticercus; Ene

2019