oxaloacetic acid has been researched along with Neoplasms in 3 studies
Oxaloacetic Acid: A dicarboxylic acid ketone that is an important metabolic intermediate of the CITRIC ACID CYCLE. It can be converted to ASPARTIC ACID by ASPARTATE TRANSAMINASE.
oxaloacetic acid : An oxodicarboxylic acid that is succinic acid bearing a single oxo group.
Neoplasms: New abnormal growth of tissue. Malignant neoplasms show a greater degree of anaplasia and have the properties of invasion and metastasis, compared to benign neoplasms.
Excerpt | Relevance | Reference |
---|---|---|
"KRAS mutated cancer cells were recently shown to rely on GOT1 to support long-term cell proliferation." | 1.48 | Inhibition of glutamate oxaloacetate transaminase 1 in cancer cell lines results in altered metabolism with increased dependency of glucose. ( Curbo, S; Karlsson, A; Krishnan, S; Li, F; Zhou, X, 2018) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 0 (0.00) | 29.6817 |
2010's | 2 (66.67) | 24.3611 |
2020's | 1 (33.33) | 2.80 |
Authors | Studies |
---|---|
Icard, P | 1 |
Wu, Z | 1 |
Fournel, L | 1 |
Coquerel, A | 1 |
Lincet, H | 1 |
Alifano, M | 1 |
Zhou, X | 1 |
Curbo, S | 1 |
Li, F | 1 |
Krishnan, S | 1 |
Karlsson, A | 1 |
Yin, C | 1 |
He, D | 1 |
Chen, S | 1 |
Tan, X | 1 |
Sang, N | 1 |
1 review available for oxaloacetic acid and Neoplasms
Article | Year |
---|---|
ATP citrate lyase: A central metabolic enzyme in cancer.
Topics: Acetyl Coenzyme A; Animals; ATP Citrate (pro-S)-Lyase; Humans; Neoplasms; Oxaloacetic Acid; Structur | 2020 |
2 other studies available for oxaloacetic acid and Neoplasms
Article | Year |
---|---|
Inhibition of glutamate oxaloacetate transaminase 1 in cancer cell lines results in altered metabolism with increased dependency of glucose.
Topics: A549 Cells; Aspartate Aminotransferase, Cytoplasmic; Cell Line, Tumor; Cellular Reprogramming; Datas | 2018 |
Exogenous pyruvate facilitates cancer cell adaptation to hypoxia by serving as an oxygen surrogate.
Topics: Acetyl Coenzyme A; Adaptation, Physiological; Adenosine Triphosphate; Cell Proliferation; Electron T | 2016 |