Page last updated: 2024-10-19

oxaloacetic acid and Neoplasms

oxaloacetic acid has been researched along with Neoplasms in 3 studies

Oxaloacetic Acid: A dicarboxylic acid ketone that is an important metabolic intermediate of the CITRIC ACID CYCLE. It can be converted to ASPARTIC ACID by ASPARTATE TRANSAMINASE.
oxaloacetic acid : An oxodicarboxylic acid that is succinic acid bearing a single oxo group.

Neoplasms: New abnormal growth of tissue. Malignant neoplasms show a greater degree of anaplasia and have the properties of invasion and metastasis, compared to benign neoplasms.

Research Excerpts

ExcerptRelevanceReference
"KRAS mutated cancer cells were recently shown to rely on GOT1 to support long-term cell proliferation."1.48Inhibition of glutamate oxaloacetate transaminase 1 in cancer cell lines results in altered metabolism with increased dependency of glucose. ( Curbo, S; Karlsson, A; Krishnan, S; Li, F; Zhou, X, 2018)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's2 (66.67)24.3611
2020's1 (33.33)2.80

Authors

AuthorsStudies
Icard, P1
Wu, Z1
Fournel, L1
Coquerel, A1
Lincet, H1
Alifano, M1
Zhou, X1
Curbo, S1
Li, F1
Krishnan, S1
Karlsson, A1
Yin, C1
He, D1
Chen, S1
Tan, X1
Sang, N1

Reviews

1 review available for oxaloacetic acid and Neoplasms

ArticleYear
ATP citrate lyase: A central metabolic enzyme in cancer.
    Cancer letters, 2020, 02-28, Volume: 471

    Topics: Acetyl Coenzyme A; Animals; ATP Citrate (pro-S)-Lyase; Humans; Neoplasms; Oxaloacetic Acid; Structur

2020

Other Studies

2 other studies available for oxaloacetic acid and Neoplasms

ArticleYear
Inhibition of glutamate oxaloacetate transaminase 1 in cancer cell lines results in altered metabolism with increased dependency of glucose.
    BMC cancer, 2018, May-11, Volume: 18, Issue:1

    Topics: A549 Cells; Aspartate Aminotransferase, Cytoplasmic; Cell Line, Tumor; Cellular Reprogramming; Datas

2018
Exogenous pyruvate facilitates cancer cell adaptation to hypoxia by serving as an oxygen surrogate.
    Oncotarget, 2016, Jul-26, Volume: 7, Issue:30

    Topics: Acetyl Coenzyme A; Adaptation, Physiological; Adenosine Triphosphate; Cell Proliferation; Electron T

2016