Page last updated: 2024-10-19

oxaloacetic acid and Glioma

oxaloacetic acid has been researched along with Glioma in 1 studies

Oxaloacetic Acid: A dicarboxylic acid ketone that is an important metabolic intermediate of the CITRIC ACID CYCLE. It can be converted to ASPARTIC ACID by ASPARTATE TRANSAMINASE.
oxaloacetic acid : An oxodicarboxylic acid that is succinic acid bearing a single oxo group.

Glioma: Benign and malignant central nervous system neoplasms derived from glial cells (i.e., astrocytes, oligodendrocytes, and ependymocytes). Astrocytes may give rise to astrocytomas (ASTROCYTOMA) or glioblastoma multiforme (see GLIOBLASTOMA). Oligodendrocytes give rise to oligodendrogliomas (OLIGODENDROGLIOMA) and ependymocytes may undergo transformation to become EPENDYMOMA; CHOROID PLEXUS NEOPLASMS; or colloid cysts of the third ventricle. (From Escourolle et al., Manual of Basic Neuropathology, 2nd ed, p21)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ruban, A1
Berkutzki, T1
Cooper, I1
Mohar, B1
Teichberg, VI1

Clinical Trials (4)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Role of Glutamate-mediate Excitotoxicity in Invasion and Progression Processes of Glioblastoma Multiforme[NCT05775458]50 participants (Anticipated)Observational2020-06-01Recruiting
Anhydrous Enol-Oxaloacetate (AEO) on Improving Fatigue in Post-COVID-19 Survivors[NCT04592354]40 participants (Anticipated)Interventional2020-10-15Recruiting
A Phase 2, Randomized, Open-Label Study of Anhydrous Enol-Oxaloacetate in Subjects With Newly Diagnosed Glioblastoma Multiforme[NCT04450160]Phase 280 participants (Anticipated)Interventional2020-12-31Not yet recruiting
A Randomized Double Blind Placebo Controlled Trial to Determine the Effects of Oxaloacetate on Improving Fatigue in ME/CFS[NCT05273372]80 participants (Anticipated)Interventional2022-03-15Enrolling by invitation
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Other Studies

1 other study available for oxaloacetic acid and Glioma

ArticleYear
Blood glutamate scavengers prolong the survival of rats and mice with brain-implanted gliomas.
    Investigational new drugs, 2012, Volume: 30, Issue:6

    Topics: Animals; Antineoplastic Agents, Alkylating; Aspartate Aminotransferases; Brain; Brain Neoplasms; Cel

2012
Blood glutamate scavengers prolong the survival of rats and mice with brain-implanted gliomas.
    Investigational new drugs, 2012, Volume: 30, Issue:6

    Topics: Animals; Antineoplastic Agents, Alkylating; Aspartate Aminotransferases; Brain; Brain Neoplasms; Cel

2012
Blood glutamate scavengers prolong the survival of rats and mice with brain-implanted gliomas.
    Investigational new drugs, 2012, Volume: 30, Issue:6

    Topics: Animals; Antineoplastic Agents, Alkylating; Aspartate Aminotransferases; Brain; Brain Neoplasms; Cel

2012
Blood glutamate scavengers prolong the survival of rats and mice with brain-implanted gliomas.
    Investigational new drugs, 2012, Volume: 30, Issue:6

    Topics: Animals; Antineoplastic Agents, Alkylating; Aspartate Aminotransferases; Brain; Brain Neoplasms; Cel

2012
Blood glutamate scavengers prolong the survival of rats and mice with brain-implanted gliomas.
    Investigational new drugs, 2012, Volume: 30, Issue:6

    Topics: Animals; Antineoplastic Agents, Alkylating; Aspartate Aminotransferases; Brain; Brain Neoplasms; Cel

2012
Blood glutamate scavengers prolong the survival of rats and mice with brain-implanted gliomas.
    Investigational new drugs, 2012, Volume: 30, Issue:6

    Topics: Animals; Antineoplastic Agents, Alkylating; Aspartate Aminotransferases; Brain; Brain Neoplasms; Cel

2012
Blood glutamate scavengers prolong the survival of rats and mice with brain-implanted gliomas.
    Investigational new drugs, 2012, Volume: 30, Issue:6

    Topics: Animals; Antineoplastic Agents, Alkylating; Aspartate Aminotransferases; Brain; Brain Neoplasms; Cel

2012
Blood glutamate scavengers prolong the survival of rats and mice with brain-implanted gliomas.
    Investigational new drugs, 2012, Volume: 30, Issue:6

    Topics: Animals; Antineoplastic Agents, Alkylating; Aspartate Aminotransferases; Brain; Brain Neoplasms; Cel

2012
Blood glutamate scavengers prolong the survival of rats and mice with brain-implanted gliomas.
    Investigational new drugs, 2012, Volume: 30, Issue:6

    Topics: Animals; Antineoplastic Agents, Alkylating; Aspartate Aminotransferases; Brain; Brain Neoplasms; Cel

2012
Blood glutamate scavengers prolong the survival of rats and mice with brain-implanted gliomas.
    Investigational new drugs, 2012, Volume: 30, Issue:6

    Topics: Animals; Antineoplastic Agents, Alkylating; Aspartate Aminotransferases; Brain; Brain Neoplasms; Cel

2012
Blood glutamate scavengers prolong the survival of rats and mice with brain-implanted gliomas.
    Investigational new drugs, 2012, Volume: 30, Issue:6

    Topics: Animals; Antineoplastic Agents, Alkylating; Aspartate Aminotransferases; Brain; Brain Neoplasms; Cel

2012
Blood glutamate scavengers prolong the survival of rats and mice with brain-implanted gliomas.
    Investigational new drugs, 2012, Volume: 30, Issue:6

    Topics: Animals; Antineoplastic Agents, Alkylating; Aspartate Aminotransferases; Brain; Brain Neoplasms; Cel

2012
Blood glutamate scavengers prolong the survival of rats and mice with brain-implanted gliomas.
    Investigational new drugs, 2012, Volume: 30, Issue:6

    Topics: Animals; Antineoplastic Agents, Alkylating; Aspartate Aminotransferases; Brain; Brain Neoplasms; Cel

2012
Blood glutamate scavengers prolong the survival of rats and mice with brain-implanted gliomas.
    Investigational new drugs, 2012, Volume: 30, Issue:6

    Topics: Animals; Antineoplastic Agents, Alkylating; Aspartate Aminotransferases; Brain; Brain Neoplasms; Cel

2012
Blood glutamate scavengers prolong the survival of rats and mice with brain-implanted gliomas.
    Investigational new drugs, 2012, Volume: 30, Issue:6

    Topics: Animals; Antineoplastic Agents, Alkylating; Aspartate Aminotransferases; Brain; Brain Neoplasms; Cel

2012
Blood glutamate scavengers prolong the survival of rats and mice with brain-implanted gliomas.
    Investigational new drugs, 2012, Volume: 30, Issue:6

    Topics: Animals; Antineoplastic Agents, Alkylating; Aspartate Aminotransferases; Brain; Brain Neoplasms; Cel

2012