Page last updated: 2024-10-19

oxaloacetic acid and Fatigue Syndrome, Chronic

oxaloacetic acid has been researched along with Fatigue Syndrome, Chronic in 1 studies

Oxaloacetic Acid: A dicarboxylic acid ketone that is an important metabolic intermediate of the CITRIC ACID CYCLE. It can be converted to ASPARTIC ACID by ASPARTATE TRANSAMINASE.
oxaloacetic acid : An oxodicarboxylic acid that is succinic acid bearing a single oxo group.

Fatigue Syndrome, Chronic: A syndrome characterized by persistent or recurrent fatigue, diffuse musculoskeletal pain, sleep disturbances, and subjective cognitive impairment of 6 months duration or longer. Symptoms are not caused by ongoing exertion; are not relieved by rest; and result in a substantial reduction of previous levels of occupational, educational, social, or personal activities. Minor alterations of immune, neuroendocrine, and autonomic function may be associated with this syndrome. There is also considerable overlap between this condition and FIBROMYALGIA. (From Semin Neurol 1998;18(2):237-42; Ann Intern Med 1994 Dec 15;121(12): 953-9)

Research Excerpts

ExcerptRelevanceReference
" Here, we examine the use of higher dosage AEO as a medical food to relieve pathological fatigue."3.11Oxaloacetate Treatment For Mental And Physical Fatigue In Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) and Long-COVID fatigue patients: a non-randomized controlled clinical trial. ( Cash, A; Kaufman, DL, 2022)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's1 (100.00)2.80

Authors

AuthorsStudies
Cash, A1
Kaufman, DL1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Anhydrous Enol-Oxaloacetate (AEO) on Improving Fatigue in Post-COVID-19 Survivors[NCT04592354]40 participants (Anticipated)Interventional2020-10-15Recruiting
REGAIN: A Randomized, Double Blind, Placebo Controlled Trial to Determine the Effects of Oxaloacetate on Improving Fatigue in Long COVID[NCT05840237]70 participants (Anticipated)Interventional2023-06-01Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

1 trial available for oxaloacetic acid and Fatigue Syndrome, Chronic

ArticleYear
Oxaloacetate Treatment For Mental And Physical Fatigue In Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) and Long-COVID fatigue patients: a non-randomized controlled clinical trial.
    Journal of translational medicine, 2022, 06-28, Volume: 20, Issue:1

    Topics: COVID-19; COVID-19 Drug Treatment; Fatigue Syndrome, Chronic; Female; Humans; Male; Mental Fatigue;

2022
Oxaloacetate Treatment For Mental And Physical Fatigue In Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) and Long-COVID fatigue patients: a non-randomized controlled clinical trial.
    Journal of translational medicine, 2022, 06-28, Volume: 20, Issue:1

    Topics: COVID-19; COVID-19 Drug Treatment; Fatigue Syndrome, Chronic; Female; Humans; Male; Mental Fatigue;

2022
Oxaloacetate Treatment For Mental And Physical Fatigue In Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) and Long-COVID fatigue patients: a non-randomized controlled clinical trial.
    Journal of translational medicine, 2022, 06-28, Volume: 20, Issue:1

    Topics: COVID-19; COVID-19 Drug Treatment; Fatigue Syndrome, Chronic; Female; Humans; Male; Mental Fatigue;

2022
Oxaloacetate Treatment For Mental And Physical Fatigue In Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) and Long-COVID fatigue patients: a non-randomized controlled clinical trial.
    Journal of translational medicine, 2022, 06-28, Volume: 20, Issue:1

    Topics: COVID-19; COVID-19 Drug Treatment; Fatigue Syndrome, Chronic; Female; Humans; Male; Mental Fatigue;

2022