Page last updated: 2024-10-19

oxaloacetic acid and Brain Ischemia

oxaloacetic acid has been researched along with Brain Ischemia in 6 studies

Oxaloacetic Acid: A dicarboxylic acid ketone that is an important metabolic intermediate of the CITRIC ACID CYCLE. It can be converted to ASPARTIC ACID by ASPARTATE TRANSAMINASE.
oxaloacetic acid : An oxodicarboxylic acid that is succinic acid bearing a single oxo group.

Brain Ischemia: Localized reduction of blood flow to brain tissue due to arterial obstruction or systemic hypoperfusion. This frequently occurs in conjunction with brain hypoxia (HYPOXIA, BRAIN). Prolonged ischemia is associated with BRAIN INFARCTION.

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (16.67)29.6817
2010's5 (83.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Pérez-Mato, M2
Ramos-Cabrer, P3
Sobrino, T3
Blanco, M1
Ruban, A1
Mirelman, D1
Menendez, P1
Castillo, J3
Campos, F3
Knapp, L2
Gellért, L1
Kocsis, K2
Kis, Z2
Farkas, T2
Vécsei, L2
Toldi, J2
Mészáros, J1
Argibay, B1
Agulla, J1
Rodríguez-González, R1
Brea, D1
Frenzel, J1
Richter, J1
Eschrich, K1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Anhydrous Enol-Oxaloacetate (AEO) on Improving Fatigue in Post-COVID-19 Survivors[NCT04592354]40 participants (Anticipated)Interventional2020-10-15Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for oxaloacetic acid and Brain Ischemia

ArticleYear
Oxaloacetate: a novel neuroprotective for acute ischemic stroke.
    The international journal of biochemistry & cell biology, 2012, Volume: 44, Issue:2

    Topics: Animals; Brain; Brain Ischemia; Excitatory Amino Acid Antagonists; Glutamic Acid; Humans; Nerve Dege

2012

Other Studies

5 other studies available for oxaloacetic acid and Brain Ischemia

ArticleYear
Human recombinant glutamate oxaloacetate transaminase 1 (GOT1) supplemented with oxaloacetate induces a protective effect after cerebral ischemia.
    Cell death & disease, 2014, Jan-09, Volume: 5

    Topics: Animals; Aspartate Aminotransferase, Cytoplasmic; Brain; Brain Ischemia; Disease Models, Animal; Hum

2014
Neuroprotective effect of oxaloacetate in a focal brain ischemic model in the rat.
    Cellular and molecular neurobiology, 2015, Volume: 35, Issue:1

    Topics: Animals; Brain Ischemia; Disease Models, Animal; Male; Neuroprotective Agents; Oxaloacetic Acid; Rat

2015
Acetyl-L-carnitine and oxaloacetate in post-treatment against LTP impairment in a rat ischemia model. An in vitro electrophysiological study.
    Journal of neural transmission (Vienna, Austria : 1996), 2015, Volume: 122, Issue:6

    Topics: Acetylcarnitine; Animals; Brain Ischemia; Disease Models, Animal; Dose-Response Relationship, Drug;

2015
Neuroprotection by glutamate oxaloacetate transaminase in ischemic stroke: an experimental study.
    Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 2011, Volume: 31, Issue:6

    Topics: Animals; Aspartate Aminotransferases; Brain; Brain Ischemia; Cells, Cultured; Endothelial Cells; Enz

2011
Pyruvate protects glucose-deprived Müller cells from nitric oxide-induced oxidative stress by radical scavenging.
    Glia, 2005, Volume: 52, Issue:4

    Topics: Adenosine Triphosphate; Animals; Animals, Newborn; Apoptosis; Brain Ischemia; Cells, Cultured; Energ

2005