oxaloacetic acid has been researched along with Amyotrophic Lateral Sclerosis in 2 studies
Oxaloacetic Acid: A dicarboxylic acid ketone that is an important metabolic intermediate of the CITRIC ACID CYCLE. It can be converted to ASPARTIC ACID by ASPARTATE TRANSAMINASE.
oxaloacetic acid : An oxodicarboxylic acid that is succinic acid bearing a single oxo group.
Amyotrophic Lateral Sclerosis: A degenerative disorder affecting upper MOTOR NEURONS in the brain and lower motor neurons in the brain stem and SPINAL CORD. Disease onset is usually after the age of 50 and the process is usually fatal within 3 to 6 years. Clinical manifestations include progressive weakness, atrophy, FASCICULATION, hyperreflexia, DYSARTHRIA, dysphagia, and eventual paralysis of respiratory function. Pathologic features include the replacement of motor neurons with fibrous ASTROCYTES and atrophy of anterior SPINAL NERVE ROOTS and corticospinal tracts. (From Adams et al., Principles of Neurology, 6th ed, pp1089-94)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 1 (50.00) | 2.80 |
| Authors | Studies |
|---|---|
| Tungtur, SK | 1 |
| Wilkins, HM | 1 |
| Rogers, RS | 1 |
| Badawi, Y | 1 |
| Sage, JM | 1 |
| Agbas, A | 1 |
| Jawdat, O | 1 |
| Barohn, RJ | 1 |
| Swerdlow, RH | 1 |
| Nishimune, H | 1 |
| Ruban, A | 1 |
| Malina, KC | 1 |
| Cooper, I | 1 |
| Graubardt, N | 1 |
| Babakin, L | 1 |
| Jona, G | 1 |
| Teichberg, VI | 1 |
2 other studies available for oxaloacetic acid and Amyotrophic Lateral Sclerosis
| Article | Year |
|---|---|
Oxaloacetate treatment preserves motor function in SOD1
Topics: Amyotrophic Lateral Sclerosis; Animals; Disease Models, Animal; Inflammation; Longevity; Mice; Motor | 2021 |
Combined Treatment of an Amyotrophic Lateral Sclerosis Rat Model with Recombinant GOT1 and Oxaloacetic Acid: A Novel Neuroprotective Treatment.
Topics: Amyotrophic Lateral Sclerosis; Animals; Aspartate Aminotransferases; Disease Models, Animal; Drug Th | 2015 |