Page last updated: 2024-10-19

oxalic acid and Nephrocalcinosis

oxalic acid has been researched along with Nephrocalcinosis in 11 studies

Oxalic Acid: A strong dicarboxylic acid occurring in many plants and vegetables. It is produced in the body by metabolism of glyoxylic acid or ascorbic acid. It is not metabolized but excreted in the urine. It is used as an analytical reagent and general reducing agent.
oxalic acid : An alpha,omega-dicarboxylic acid that is ethane substituted by carboxyl groups at positions 1 and 2.

Nephrocalcinosis: A condition characterized by calcification of the renal tissue itself. It is usually seen in distal RENAL TUBULAR ACIDOSIS with calcium deposition in the DISTAL KIDNEY TUBULES and the surrounding interstitium. Nephrocalcinosis causes RENAL INSUFFICIENCY.

Research Excerpts

ExcerptRelevanceReference
"Experimental induction of hyperoxaluria by ethylene glycol (EG) administration is disapproved as it causes metabolic acidosis while the oral administration of chemically synthesized potassium oxalate (KOx) diet does not mimic our natural system."3.88Oral administration of oxalate-enriched spinach extract as an improved methodology for the induction of dietary hyperoxaluric nephrocalcinosis in experimental rats. ( Albert, A; Ganesan, D; Govindan Sadasivam, S; Mariaraj Sivakumar, S; Paul, E; Ponnusamy, S; Prabhakaran, R; Tiwari, V, 2018)
"Stone formation and nephrocalcinosis are both very common features of primary hyperoxaluria, yet the extent of each disease varies markedly between patients."1.42Nephrocalcinosis is a risk factor for kidney failure in primary hyperoxaluria. ( Bergstralh, EJ; Lieske, JC; Mehta, RA; Milliner, DS; Tang, X; Vrtiska, TJ, 2015)
"Nephrocalcinosis is not uncommon in preterm infants, and elevated urinary oxalate excretion is known to be one of the main risk factors."1.30Oxalate, citrate, and sulfate concentration in human milk compared with formula preparations: influence on urinary anion excretion. ( Bauerfeld, C; Hoppe, B; Langman, CB; Roth, B, 1998)
"Hypercalciuria and nephrocalcinosis are not uncommon in patients with Wilson's disease but have only once been reported as the presenting sign."1.29Hypercalciuria and nephrocalcinosis, a feature of Wilson's disease. ( Forster, I; Hoppe, B; Leumann, E; Neuhaus, T; Superti-Furga, A, 1993)
"Most attempts to treat primary hyperoxaluria by renal transplantation have been unsuccessful because of rapid recurrence of nephrocalcinosis with uraemia and systemic oxalosis."1.27Renal transplantation in primary hyperoxaluria. ( Mansell, MA; Morgan, SH; Purkiss, P; Watts, RW, 1987)

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19903 (27.27)18.7374
1990's5 (45.45)18.2507
2000's0 (0.00)29.6817
2010's3 (27.27)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Albert, A2
Tiwari, V1
Paul, E2
Ponnusamy, S2
Ganesan, D1
Prabhakaran, R1
Mariaraj Sivakumar, S1
Govindan Sadasivam, S1
Mishra, SR1
Vignesh, AG1
Sivakumar, SM1
Sivasamy, G1
Sadasivam, SG1
Tang, X1
Bergstralh, EJ1
Mehta, RA1
Vrtiska, TJ1
Milliner, DS1
Lieske, JC1
Hoppe, B2
Neuhaus, T1
Superti-Furga, A1
Forster, I1
Leumann, E1
Roth, B1
Bauerfeld, C1
Langman, CB1
Koh, ET1
Min, KW1
Sakly, R1
Hdhili, A1
Zarrouk, K1
Mbazaa, A1
Buck, AC1
Davies, RL1
Harrison, T1
Watts, RW1
Morgan, SH1
Mansell, MA1
Purkiss, P1
Martí-Bonmatí, L1
de Juan Tomás, J1
Ripollés González, T1
Rodríguez Cuervo, B1
Muro Velilla, MD1
Kurbanova, EG1
Mishchenko, BP1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
[NCT00249951]Phase 380 participants (Actual)Interventional2005-11-30Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Other Studies

11 other studies available for oxalic acid and Nephrocalcinosis

ArticleYear
Oral administration of oxalate-enriched spinach extract as an improved methodology for the induction of dietary hyperoxaluric nephrocalcinosis in experimental rats.
    Toxicology mechanisms and methods, 2018, Volume: 28, Issue:3

    Topics: Administration, Oral; Animals; Biomarkers; Crystallization; Disease Models, Animal; Ethylene Glycol;

2018
Designer probiotic Lactobacillus plantarum expressing oxalate decarboxylase developed using group II intron degrades intestinal oxalate in hyperoxaluric rats.
    Microbiological research, 2018, Volume: 215

    Topics: Alanine Racemase; Animals; Bacterial Proteins; Calcium; Calcium Oxalate; Carboxy-Lyases; Cell Adhesi

2018
Nephrocalcinosis is a risk factor for kidney failure in primary hyperoxaluria.
    Kidney international, 2015, Volume: 87, Issue:3

    Topics: Adolescent; Adult; Age of Onset; Child; Child, Preschool; Citric Acid; Female; Humans; Hyperoxaluria

2015
Hypercalciuria and nephrocalcinosis, a feature of Wilson's disease.
    Nephron, 1993, Volume: 65, Issue:3

    Topics: Adolescent; Calcium; Hematuria; Hepatolenticular Degeneration; Humans; Kidney Calculi; Male; Nephroc

1993
Oxalate, citrate, and sulfate concentration in human milk compared with formula preparations: influence on urinary anion excretion.
    Journal of pediatric gastroenterology and nutrition, 1998, Volume: 27, Issue:4

    Topics: Anions; Citric Acid; Female; Humans; Infant Food; Infant, Newborn; Milk, Human; Nephrocalcinosis; Ox

1998
Dietary fructose produces greater nephrocalcinosis in female than in male magnesium-deficient rats.
    Magnesium research, 1991, Volume: 4, Issue:2

    Topics: Analysis of Variance; Animals; Calcium; Dietary Carbohydrates; Female; Fructose; Hydrogen-Ion Concen

1991
[The effect of the administration of a high dose of vitamin D3 on calculus formation in rats].
    Annales d'urologie, 1990, Volume: 24, Issue:7

    Topics: Animals; Calcium; Cholecalciferol; Creatinine; Kidney; Kidney Calculi; Male; Nephrocalcinosis; Oxala

1990
The protective role of eicosapentaenoic acid [EPA] in the pathogenesis of nephrolithiasis.
    The Journal of urology, 1991, Volume: 146, Issue:1

    Topics: Adult; Aged; Animals; Calcium; Disease Models, Animal; Drug Evaluation; Drug Evaluation, Preclinical

1991
Renal transplantation in primary hyperoxaluria.
    Annals of the Academy of Medicine, Singapore, 1987, Volume: 16, Issue:2

    Topics: Glomerular Filtration Rate; Humans; Hyperoxaluria; Hyperoxaluria, Primary; Kidney Transplantation; N

1987
[Primary hyperoxaluria and oxalosis: radiological aspects].
    Archivos espanoles de urologia, 1986, Volume: 39, Issue:4

    Topics: Adolescent; Calcium Oxalate; Child, Preschool; Female; Humans; Kidney Calculi; Male; Nephrocalcinosi

1986
[Pyridoxine levels in the bodies of patients with dysmetabolic nephropathy].
    Pediatriia, 1985, Issue:10

    Topics: Adolescent; Calcium; Child; Child, Preschool; Humans; Nephrocalcinosis; Oxalates; Oxalic Acid; Pyrid

1985