oxalic acid has been researched along with Neoplasms in 5 studies
Oxalic Acid: A strong dicarboxylic acid occurring in many plants and vegetables. It is produced in the body by metabolism of glyoxylic acid or ascorbic acid. It is not metabolized but excreted in the urine. It is used as an analytical reagent and general reducing agent.
oxalic acid : An alpha,omega-dicarboxylic acid that is ethane substituted by carboxyl groups at positions 1 and 2.
Neoplasms: New abnormal growth of tissue. Malignant neoplasms show a greater degree of anaplasia and have the properties of invasion and metastasis, compared to benign neoplasms.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Many cancer cells exhibit a glycolytic phenotype known as the Warburg effect, in which elevated LDH levels enhance the conversion of glucose to lactate, making LDH an attractive therapeutic target for oncology." | 1.42 | Structures of lactate dehydrogenase A (LDHA) in apo, ternary and inhibitor-bound forms. ( Craig, L; Kolappan, S; McEachern, EJ; Mosi, R; Shen, DL; Sun, J; Vocadlo, DJ, 2015) |
| "Targeted therapy for the treatment of cancers using nanoparticles (NPs) decorated with transferrin (Tf) has been relatively successful, as several such nanocarriers are currently undergoing clinical trials." | 1.40 | Improving the systemic drug delivery efficacy of nanoparticles using a transferrin variant for targeting. ( Chiu, RY; Kamei, DT; Liu, CT; Tsuji, T; Wang, J; Wang, SJ, 2014) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (20.00) | 29.6817 |
| 2010's | 3 (60.00) | 24.3611 |
| 2020's | 1 (20.00) | 2.80 |
| Authors | Studies |
|---|---|
| Peng, X | 1 |
| Yang, G | 1 |
| Shi, Y | 1 |
| Zhou, Y | 1 |
| Zhang, M | 1 |
| Li, S | 1 |
| Chiu, RY | 1 |
| Tsuji, T | 1 |
| Wang, SJ | 1 |
| Wang, J | 1 |
| Liu, CT | 1 |
| Kamei, DT | 1 |
| Kolappan, S | 1 |
| Shen, DL | 1 |
| Mosi, R | 1 |
| Sun, J | 1 |
| McEachern, EJ | 1 |
| Vocadlo, DJ | 1 |
| Craig, L | 1 |
| Robitaille, L | 1 |
| Mamer, OA | 1 |
| Miller, WH | 1 |
| Levine, M | 1 |
| Assouline, S | 1 |
| Melnychuk, D | 1 |
| Rousseau, C | 1 |
| Hoffer, LJ | 1 |
| Takeshita, M | 1 |
| Banno, Y | 1 |
| Nakamura, M | 1 |
| Otsuka, M | 1 |
| Teramachi, H | 1 |
| Tsuchiya, T | 1 |
| Itoh, Y | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Phase 2 Study of High Dose Ascorbic Acid in Solid Tumor Disease[NCT01125449] | Phase 2 | 30 participants (Anticipated) | Interventional | 2011-01-31 | Suspended (stopped due to Awaiting response from FDA as to status of parenteral ascorbic acid manufactured by Bioniche (Ireland).) | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 trial available for oxalic acid and Neoplasms
| Article | Year |
|---|---|
Oxalic acid excretion after intravenous ascorbic acid administration.
Topics: Adult; Aged; Antioxidants; Ascorbic Acid; Calcium Oxalate; Female; Humans; Hyperoxaluria; Injections | 2009 |
4 other studies available for oxalic acid and Neoplasms
| Article | Year |
|---|---|
Box-Behnken design based statistical modeling for the extraction and physicochemical properties of pectin from sunflower heads and the comparison with commercial low-methoxyl pectin.
Topics: Biological Products; Cosmetics; Flowers; Food Industry; Gastrointestinal Diseases; Helianthus; Human | 2020 |
Improving the systemic drug delivery efficacy of nanoparticles using a transferrin variant for targeting.
Topics: Animals; Cell Line, Tumor; Drug Carriers; Drug Delivery Systems; Humans; Iron; Male; Mice; Models, B | 2014 |
Structures of lactate dehydrogenase A (LDHA) in apo, ternary and inhibitor-bound forms.
Topics: Binding Sites; Crystallography, X-Ray; Enzyme Inhibitors; Humans; Isoenzymes; L-Lactate Dehydrogenas | 2015 |
The pivotal role of intracellular calcium in oxaliplatin-induced inhibition of neurite outgrowth but not cell death in differentiated PC12 cells.
Topics: Animals; Antineoplastic Agents; Calcium; Calcium Gluconate; Cell Death; Cell Differentiation; Chelat | 2011 |