Page last updated: 2024-10-19

oxalic acid and Neoplasms

oxalic acid has been researched along with Neoplasms in 5 studies

Oxalic Acid: A strong dicarboxylic acid occurring in many plants and vegetables. It is produced in the body by metabolism of glyoxylic acid or ascorbic acid. It is not metabolized but excreted in the urine. It is used as an analytical reagent and general reducing agent.
oxalic acid : An alpha,omega-dicarboxylic acid that is ethane substituted by carboxyl groups at positions 1 and 2.

Neoplasms: New abnormal growth of tissue. Malignant neoplasms show a greater degree of anaplasia and have the properties of invasion and metastasis, compared to benign neoplasms.

Research Excerpts

ExcerptRelevanceReference
"Many cancer cells exhibit a glycolytic phenotype known as the Warburg effect, in which elevated LDH levels enhance the conversion of glucose to lactate, making LDH an attractive therapeutic target for oncology."1.42Structures of lactate dehydrogenase A (LDHA) in apo, ternary and inhibitor-bound forms. ( Craig, L; Kolappan, S; McEachern, EJ; Mosi, R; Shen, DL; Sun, J; Vocadlo, DJ, 2015)
"Targeted therapy for the treatment of cancers using nanoparticles (NPs) decorated with transferrin (Tf) has been relatively successful, as several such nanocarriers are currently undergoing clinical trials."1.40Improving the systemic drug delivery efficacy of nanoparticles using a transferrin variant for targeting. ( Chiu, RY; Kamei, DT; Liu, CT; Tsuji, T; Wang, J; Wang, SJ, 2014)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (20.00)29.6817
2010's3 (60.00)24.3611
2020's1 (20.00)2.80

Authors

AuthorsStudies
Peng, X1
Yang, G1
Shi, Y1
Zhou, Y1
Zhang, M1
Li, S1
Chiu, RY1
Tsuji, T1
Wang, SJ1
Wang, J1
Liu, CT1
Kamei, DT1
Kolappan, S1
Shen, DL1
Mosi, R1
Sun, J1
McEachern, EJ1
Vocadlo, DJ1
Craig, L1
Robitaille, L1
Mamer, OA1
Miller, WH1
Levine, M1
Assouline, S1
Melnychuk, D1
Rousseau, C1
Hoffer, LJ1
Takeshita, M1
Banno, Y1
Nakamura, M1
Otsuka, M1
Teramachi, H1
Tsuchiya, T1
Itoh, Y1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Phase 2 Study of High Dose Ascorbic Acid in Solid Tumor Disease[NCT01125449]Phase 230 participants (Anticipated)Interventional2011-01-31Suspended (stopped due to Awaiting response from FDA as to status of parenteral ascorbic acid manufactured by Bioniche (Ireland).)
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

1 trial available for oxalic acid and Neoplasms

ArticleYear
Oxalic acid excretion after intravenous ascorbic acid administration.
    Metabolism: clinical and experimental, 2009, Volume: 58, Issue:2

    Topics: Adult; Aged; Antioxidants; Ascorbic Acid; Calcium Oxalate; Female; Humans; Hyperoxaluria; Injections

2009

Other Studies

4 other studies available for oxalic acid and Neoplasms

ArticleYear
Box-Behnken design based statistical modeling for the extraction and physicochemical properties of pectin from sunflower heads and the comparison with commercial low-methoxyl pectin.
    Scientific reports, 2020, 02-27, Volume: 10, Issue:1

    Topics: Biological Products; Cosmetics; Flowers; Food Industry; Gastrointestinal Diseases; Helianthus; Human

2020
Improving the systemic drug delivery efficacy of nanoparticles using a transferrin variant for targeting.
    Journal of controlled release : official journal of the Controlled Release Society, 2014, Apr-28, Volume: 180

    Topics: Animals; Cell Line, Tumor; Drug Carriers; Drug Delivery Systems; Humans; Iron; Male; Mice; Models, B

2014
Structures of lactate dehydrogenase A (LDHA) in apo, ternary and inhibitor-bound forms.
    Acta crystallographica. Section D, Biological crystallography, 2015, Volume: 71, Issue:Pt 2

    Topics: Binding Sites; Crystallography, X-Ray; Enzyme Inhibitors; Humans; Isoenzymes; L-Lactate Dehydrogenas

2015
The pivotal role of intracellular calcium in oxaliplatin-induced inhibition of neurite outgrowth but not cell death in differentiated PC12 cells.
    Chemical research in toxicology, 2011, Nov-21, Volume: 24, Issue:11

    Topics: Animals; Antineoplastic Agents; Calcium; Calcium Gluconate; Cell Death; Cell Differentiation; Chelat

2011