oxalic acid has been researched along with Hyperoxaluria, Primary in 29 studies
Oxalic Acid: A strong dicarboxylic acid occurring in many plants and vegetables. It is produced in the body by metabolism of glyoxylic acid or ascorbic acid. It is not metabolized but excreted in the urine. It is used as an analytical reagent and general reducing agent.
oxalic acid : An alpha,omega-dicarboxylic acid that is ethane substituted by carboxyl groups at positions 1 and 2.
Hyperoxaluria, Primary: A genetic disorder characterized by excretion of large amounts of OXALATES in urine; NEPHROLITHIASIS; NEPHROCALCINOSIS; early onset of RENAL FAILURE; and often a generalized deposit of CALCIUM OXALATE. There are subtypes classified by the enzyme defects in glyoxylate metabolism.
| Excerpt | Relevance | Reference |
|---|---|---|
| " B6 was administered orally starting at 5 mg/kg body weight per day and given in increments of 5 mg/kg every 6 weeks, up to a final dosage of 20 mg/kg per day at week 24." | 2.79 | Vitamin B6 in primary hyperoxaluria I: first prospective trial after 40 years of practice. ( Beck, BB; Franklin, J; Hero, B; Hoppe, B; Hoyer-Kuhn, H; Kohbrok, S; Volland, R, 2014) |
| "Primary hyperoxaluria is a rare hereditary disease." | 2.39 | [Primary hyperoxaluria]. ( De Pauw, L; Toussaint, C, 1996) |
| "Patients with primary hyperoxaluria experience kidney stones from a young age and can develop progressive oxalate nephropathy." | 1.56 | End Points for Clinical Trials in Primary Hyperoxaluria. ( Allain, M; Blank, M; Dehmel, B; Fargue, S; Groothoff, J; Hollander, K; Knight, J; Lieske, JC; Lowther, WT; McGregor, TL; Milliner, DS; Rosskamp, R; Rumsby, G; Thompson, A; West, M; Yang, S, 2020) |
| "Stone formation and nephrocalcinosis are both very common features of primary hyperoxaluria, yet the extent of each disease varies markedly between patients." | 1.42 | Nephrocalcinosis is a risk factor for kidney failure in primary hyperoxaluria. ( Bergstralh, EJ; Lieske, JC; Mehta, RA; Milliner, DS; Tang, X; Vrtiska, TJ, 2015) |
| "Diagnosis of primary hyperoxaluria type I was made by measuring alanine/glyoxylate aminotransferase activity in a liver biopsy." | 1.30 | Late onset primary oxalosis type I: an uncommon presentation of a rare disease. ( Anthuber, M; Glück, T; Krämer, BK; Lang, B; Rogler, G; Rüschoff, J; Schölmerich, J; Schweda, F; Zülke, C, 1998) |
| "Primary oxalosis is a rare inborn error of oxalate metabolism." | 1.28 | Primary oxalosis mimicking hyperparathyroidism diagnosed after long-term hemodialysis. ( Cadario, A; Canavese, C; Marangella, M; Massara, C; Pavan, I; Petrarulo, M; Portigliatti Barbos, M; Rotolo, U; Salomone, M, 1990) |
| "Primary hyperoxaluria has not been reported as a spontaneous disease in the dog, although it is a well-known, but rare, inherited metabolic disease of man." | 1.28 | Oxalate nephropathy in a Tibetan spaniel litter. A probable case of primary hyperoxaluria. ( Arnesen, K; Jansen, JH, 1990) |
| "Most attempts to treat primary hyperoxaluria by renal transplantation have been unsuccessful because of rapid recurrence of nephrocalcinosis with uraemia and systemic oxalosis." | 1.27 | Renal transplantation in primary hyperoxaluria. ( Mansell, MA; Morgan, SH; Purkiss, P; Watts, RW, 1987) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (17.24) | 18.7374 |
| 1990's | 15 (51.72) | 18.2507 |
| 2000's | 4 (13.79) | 29.6817 |
| 2010's | 3 (10.34) | 24.3611 |
| 2020's | 2 (6.90) | 2.80 |
| Authors | Studies |
|---|---|
| Milliner, DS | 3 |
| McGregor, TL | 1 |
| Thompson, A | 1 |
| Dehmel, B | 1 |
| Knight, J | 1 |
| Rosskamp, R | 1 |
| Blank, M | 1 |
| Yang, S | 1 |
| Fargue, S | 1 |
| Rumsby, G | 1 |
| Groothoff, J | 1 |
| Allain, M | 1 |
| West, M | 1 |
| Hollander, K | 1 |
| Lowther, WT | 1 |
| Lieske, JC | 2 |
| Letavernier, E | 1 |
| Daudon, M | 1 |
| Hoyer-Kuhn, H | 1 |
| Kohbrok, S | 1 |
| Volland, R | 1 |
| Franklin, J | 1 |
| Hero, B | 1 |
| Beck, BB | 1 |
| Hoppe, B | 1 |
| Tang, X | 1 |
| Bergstralh, EJ | 1 |
| Mehta, RA | 1 |
| Vrtiska, TJ | 1 |
| Elgstoen, KB | 1 |
| Belhaj, R | 1 |
| Hayder, N | 1 |
| Gargueh, T | 1 |
| Zorguati, M | 1 |
| Marrakchi, O | 1 |
| Abdelhak, S | 1 |
| Lakhoua, R | 1 |
| Abdelmoula, J | 1 |
| ZAREMBSKI, PM | 1 |
| HODGKINSON, A | 1 |
| Sugimoto, T | 1 |
| Kamikawa, S | 1 |
| Ishii, K | 1 |
| Schulze, MR | 1 |
| Wachter, R | 1 |
| Schmeisser, A | 1 |
| Fischer, R | 1 |
| Strasser, RH | 1 |
| Woolfson, RG | 1 |
| Mansell, MA | 2 |
| De Pauw, L | 2 |
| Toussaint, C | 2 |
| Cordonnier, C | 1 |
| Noel, C | 1 |
| Gosselin, B | 1 |
| Watts, RW | 2 |
| Ogawa, Y | 1 |
| Hatano, T | 1 |
| Glück, T | 1 |
| Krämer, BK | 1 |
| Zülke, C | 1 |
| Rüschoff, J | 1 |
| Rogler, G | 1 |
| Schweda, F | 1 |
| Anthuber, M | 1 |
| Lang, B | 1 |
| Schölmerich, J | 1 |
| Cochat, P | 1 |
| Monico, CG | 1 |
| Petrarulo, M | 2 |
| Marangella, M | 2 |
| Cosseddu, D | 1 |
| Linari, F | 1 |
| Polinsky, MS | 1 |
| Dunn, S | 1 |
| Kaiser, BA | 1 |
| Schulman, SL | 1 |
| Wolfson, BJ | 1 |
| Elfenbein, IB | 1 |
| Baluarte, HJ | 1 |
| Kasidas, GP | 1 |
| Nemat, S | 1 |
| Rose, GA | 2 |
| Ruder, H | 1 |
| Otto, G | 2 |
| Schutgens, RB | 1 |
| Querfeld, U | 1 |
| Wanders, RJ | 1 |
| Herzog, KH | 1 |
| Wölfel, P | 1 |
| Pomer, S | 1 |
| Schärer, K | 2 |
| Schürmann, G | 1 |
| Wingen, AM | 1 |
| Herfarth, C | 1 |
| Gelin, M | 1 |
| Danpure, CJ | 1 |
| Vereerstraeten, P | 1 |
| Adler, M | 1 |
| Abramowicz, D | 1 |
| Canavese, C | 1 |
| Salomone, M | 1 |
| Massara, C | 1 |
| Portigliatti Barbos, M | 1 |
| Cadario, A | 1 |
| Pavan, I | 1 |
| Rotolo, U | 1 |
| Jansen, JH | 1 |
| Arnesen, K | 1 |
| Frosch, M | 1 |
| Kuwertz-Bröking, E | 1 |
| Bulla, M | 1 |
| von Bassewitz, DB | 1 |
| Leusmann, DB | 1 |
| Suyama, I | 1 |
| Isshiki, G | 1 |
| Ono, K | 1 |
| Ono, H | 1 |
| Ono, T | 1 |
| Kikawa, K | 1 |
| Oh, Y | 1 |
| Morgan, SH | 1 |
| Purkiss, P | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| PILOTSTUDIE ZUR PYRIDOXALPHOSPHATTHERAPIE BEI PATIENTEN MIT PRIMÄRER HYPEROXALURIE TYP I (PHOX-B6-PILOT) Pilot Trial on Treatment of Patients With Primary Hyperoxaluria Type I With Pyridoxal-phosphate[NCT01281878] | Phase 2 | 12 participants (Actual) | Interventional | 2010-12-31 | Completed | ||
| Scientific Basis for a Newborn Screening for Cystinosis and Primary Hyperoxaluria[NCT05843851] | 200,000 participants (Anticipated) | Interventional | 2022-03-15 | Recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
7 reviews available for oxalic acid and Hyperoxaluria, Primary
| Article | Year |
|---|---|
Stiripentol identifies a therapeutic target to reduce oxaluria.
Topics: Dioxolanes; Humans; Hyperoxaluria; Hyperoxaluria, Primary; L-Lactate Dehydrogenase; Oxalic Acid | 2020 |
Hyperoxaluria and renal calculi.
Topics: Crystallization; Female; Humans; Hyperoxaluria; Hyperoxaluria, Primary; Kidney Calculi; Male; Oxalat | 1994 |
[Primary hyperoxaluria].
Topics: Biopsy; Diet; Glycolates; Glyoxylates; Humans; Hyperoxaluria, Primary; Ilium; Metabolism, Inborn Err | 1996 |
[Oxalosis].
Topics: Calcinosis; Humans; Hyperoxaluria, Primary; Oxalates; Oxalic Acid | 1995 |
Primary hyperoxaluria.
Topics: Calcium Oxalate; Glyoxylates; Humans; Hyperoxaluria, Primary; Liver; Microbodies; Mutation; Oxalates | 1997 |
[Primary hyperoxaluria type 1 (PH1)].
Topics: Biomarkers; Glycolates; Humans; Hyperoxaluria, Primary; Minisatellite Repeats; Mutation; Oxalates; O | 1998 |
Primary hyperoxaluria type 1.
Topics: Child; Female; Glycolates; Humans; Hyperoxaluria, Primary; Kidney Failure, Chronic; Kidney Transplan | 1999 |
1 trial available for oxalic acid and Hyperoxaluria, Primary
| Article | Year |
|---|---|
Vitamin B6 in primary hyperoxaluria I: first prospective trial after 40 years of practice.
Topics: Administration, Oral; Adolescent; Biomarkers; Child; Female; Genetic Predisposition to Disease; Germ | 2014 |
Vitamin B6 in primary hyperoxaluria I: first prospective trial after 40 years of practice.
Topics: Administration, Oral; Adolescent; Biomarkers; Child; Female; Genetic Predisposition to Disease; Germ | 2014 |
Vitamin B6 in primary hyperoxaluria I: first prospective trial after 40 years of practice.
Topics: Administration, Oral; Adolescent; Biomarkers; Child; Female; Genetic Predisposition to Disease; Germ | 2014 |
Vitamin B6 in primary hyperoxaluria I: first prospective trial after 40 years of practice.
Topics: Administration, Oral; Adolescent; Biomarkers; Child; Female; Genetic Predisposition to Disease; Germ | 2014 |
21 other studies available for oxalic acid and Hyperoxaluria, Primary
| Article | Year |
|---|---|
End Points for Clinical Trials in Primary Hyperoxaluria.
Topics: Biomarkers; Disease Progression; Endpoint Determination; Glomerular Filtration Rate; Humans; Hyperox | 2020 |
Nephrocalcinosis is a risk factor for kidney failure in primary hyperoxaluria.
Topics: Adolescent; Adult; Age of Onset; Child; Child, Preschool; Citric Acid; Female; Humans; Hyperoxaluria | 2015 |
Liquid chromatography-tandem mass spectrometry method for routine measurement of oxalic acid in human plasma.
Topics: Chromatography, High Pressure Liquid; Drug Stability; Freezing; Humans; Hyperoxaluria, Primary; Oxal | 2008 |
[Biochemical and molecular diagnosis of primary hyperoxaluria type 1: Tunisian study about 15 cases].
Topics: Adolescent; Calcium; Calcium Oxalate; Child; Child, Preschool; Consanguinity; Crystallization; Femal | 2011 |
THE RENAL CLEARANCE OF OXALIC ACID IN NORMAL SUBJECTS AND IN PATIENTS WITH PRIMARY HYPEROXALURIA.
Topics: Body Fluids; Humans; Hyperoxaluria, Primary; Metabolic Diseases; Oxalates; Oxalic Acid; Urine | 1963 |
[Oxalate, oxalic acid].
Topics: Adult; Humans; Hyperoxaluria, Primary; Oxalates; Oxalic Acid | 2004 |
Restrictive cardiomyopathy in a patient with primary hyperoxaluria type II.
Topics: Adult; Biomarkers; Cardiomyopathy, Restrictive; Humans; Hyperoxaluria, Primary; Hypertrophy, Left Ve | 2006 |
Late onset primary oxalosis type I: an uncommon presentation of a rare disease.
Topics: Female; Humans; Hyperoxaluria, Primary; Kidney Transplantation; Liver Transplantation; Middle Aged; | 1998 |
Combined liver-kidney and kidney-alone transplantation in primary hyperoxaluria.
Topics: Adolescent; Adult; Female; Graft Rejection; Humans; Hyperoxaluria, Primary; Kidney; Kidney Transplan | 2001 |
High-performance liquid chromatographic assay for L-glyceric acid in body fluids. Application in primary hyperoxaluria type 2.
Topics: Body Fluids; Chromatography, High Pressure Liquid; Glyceric Acids; Humans; Hydrogen-Ion Concentratio | 1992 |
Combined liver-kidney transplantation in a child with primary hyperoxaluria.
Topics: Child, Preschool; Graft Rejection; Humans; Hyperoxaluria, Primary; Kidney Failure, Chronic; Kidney T | 1991 |
Plasma oxalate and creatinine and oxalate/creatinine clearance ratios in normal subjects and in primary hyperoxaluria. Evidence for renal hyperoxaluria.
Topics: Creatinine; Diuresis; Humans; Hyperoxaluria, Primary; Kidney; Metabolic Clearance Rate; Oxalates; Ox | 1990 |
Excessive urinary oxalate excretion after combined renal and hepatic transplantation for correction of hyperoxaluria type 1.
Topics: Child, Preschool; Creatinine; Humans; Hyperoxaluria, Primary; Kidney; Kidney Transplantation; Liver | 1990 |
Early liver transplantation for primary hyperoxaluria type 1 in an infant with chronic renal failure.
Topics: Acute Kidney Injury; Amino Acid Metabolism, Inborn Errors; Female; Humans; Hyperoxaluria, Primary; I | 1990 |
Combined liver-kidney transplantation in primary hyperoxaluria type 1.
Topics: Female; Humans; Hyperoxaluria, Primary; Infant; Kidney Transplantation; Liver Transplantation; Oxala | 1990 |
Primary oxalosis mimicking hyperparathyroidism diagnosed after long-term hemodialysis.
Topics: Adult; Biopsy; Bone and Bones; Diagnosis, Differential; Glycolates; Humans; Hyperoxaluria, Primary; | 1990 |
Oxalate nephropathy in a Tibetan spaniel litter. A probable case of primary hyperoxaluria.
Topics: Animals; Dog Diseases; Dogs; Female; Hyperoxaluria; Hyperoxaluria, Primary; Male; Oxalates; Oxalic A | 1990 |
[Type I oxalosis in childhood--studies within the scope of terminal renal failure in the child].
Topics: Adolescent; Child; Child, Preschool; Female; Follow-Up Studies; Humans; Hyperoxaluria; Hyperoxaluria | 1989 |
[Significance of oxalic acid analysis in clinical tests].
Topics: Adult; Chromatography, Gas; Chromatography, High Pressure Liquid; Colorimetry; Humans; Hyperoxaluria | 1989 |
Effect of vitamin C supplementation on renal oxalate deposits in five-sixths nephrectomized rats.
Topics: Animals; Ascorbic Acid; Hyperoxaluria, Primary; Kidney Failure, Chronic; Kidney Tubules; Male; Nephr | 1989 |
Renal transplantation in primary hyperoxaluria.
Topics: Glomerular Filtration Rate; Humans; Hyperoxaluria; Hyperoxaluria, Primary; Kidney Transplantation; N | 1987 |