oxalic acid has been researched along with Down Syndrome in 2 studies
Oxalic Acid: A strong dicarboxylic acid occurring in many plants and vegetables. It is produced in the body by metabolism of glyoxylic acid or ascorbic acid. It is not metabolized but excreted in the urine. It is used as an analytical reagent and general reducing agent.
oxalic acid : An alpha,omega-dicarboxylic acid that is ethane substituted by carboxyl groups at positions 1 and 2.
Down Syndrome: A chromosome disorder associated either with an extra chromosome 21 or an effective trisomy for chromosome 21. Clinical manifestations include hypotonia, short stature, brachycephaly, upslanting palpebral fissures, epicanthus, Brushfield spots on the iris, protruding tongue, small ears, short, broad hands, fifth finger clinodactyly, Simian crease, and moderate to severe INTELLECTUAL DISABILITY. Cardiac and gastrointestinal malformations, a marked increase in the incidence of LEUKEMIA, and the early onset of ALZHEIMER DISEASE are also associated with this condition. Pathologic features include the development of NEUROFIBRILLARY TANGLES in neurons and the deposition of AMYLOID BETA-PROTEIN, similar to the pathology of ALZHEIMER DISEASE. (Menkes, Textbook of Child Neurology, 5th ed, p213)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Some studies of children with Down syndrome have found mild abnormalities in the metabolism of pyridoxine (vitamin B(6)); therefore the present question is whether such abnormalities might also be present in the amniotic fluid of fetuses with Down syndrome." | 7.74 | Pyridoxine-related metabolite concentrations in normal and Down syndrome amniotic fluid. ( Baggot, PJ; DeNicola, NG; Eliseo, AJ; Kalamarides, JA; Shoemaker, JD, 2008) |
| "Some studies of children with Down syndrome have found mild abnormalities in the metabolism of pyridoxine (vitamin B(6)); therefore the present question is whether such abnormalities might also be present in the amniotic fluid of fetuses with Down syndrome." | 3.74 | Pyridoxine-related metabolite concentrations in normal and Down syndrome amniotic fluid. ( Baggot, PJ; DeNicola, NG; Eliseo, AJ; Kalamarides, JA; Shoemaker, JD, 2008) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (50.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| MCCOY, EE | 1 |
| ANAST, CS | 1 |
| NAYLOR, JJ | 1 |
| Baggot, PJ | 1 |
| Eliseo, AJ | 1 |
| DeNicola, NG | 1 |
| Kalamarides, JA | 1 |
| Shoemaker, JD | 1 |
2 other studies available for oxalic acid and Down Syndrome
| Article | Year |
|---|---|
THE EXCRETION OF OXALIC ACID FOLLOWING DEOXYPYRIDOXINE AND TRYPTOPHAN ADMINISTRATION IN MONGOLOID AND NONMONGOLOID SUBJECTS.
Topics: Adolescent; Asian People; Biomedical Research; Child; Down Syndrome; Humans; Metabolism; Oxalates; O | 1964 |
Pyridoxine-related metabolite concentrations in normal and Down syndrome amniotic fluid.
Topics: Amniotic Fluid; Biomarkers; Case-Control Studies; Down Syndrome; Female; Humans; Kynurenine; Oxalic | 2008 |