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oxalic acid and Disease Models, Animal

oxalic acid has been researched along with Disease Models, Animal in 14 studies

Oxalic Acid: A strong dicarboxylic acid occurring in many plants and vegetables. It is produced in the body by metabolism of glyoxylic acid or ascorbic acid. It is not metabolized but excreted in the urine. It is used as an analytical reagent and general reducing agent.
oxalic acid : An alpha,omega-dicarboxylic acid that is ethane substituted by carboxyl groups at positions 1 and 2.

Disease Models, Animal: Naturally-occurring or experimentally-induced animal diseases with pathological processes analogous to human diseases.

Research Excerpts

ExcerptRelevanceReference
"Nephrolithiasis is one of the most common urinary tract disorders, with the majority of kidney stones composed of calcium oxalate (CaOx)."7.83Sulfate and thiosulfate inhibit oxalate transport via a dPrestin (Slc26a6)-dependent mechanism in an insect model of calcium oxalate nephrolithiasis. ( Anderson, JB; Cabrero, P; Dow, JA; Gallo, CJ; Hirata, T; Landry, GM; Romero, MF, 2016)
"The use of hydroxyproline (HP) to generate hyperoxaluria in the rat is a problem because it is impossible to separate the effect of oxalate on renal injury from the effects of HP and the large array of metabolic intermediates formed when HP is converted to oxalate."7.77Improved methodology to induce hyperoxaluria without treatment using hydroxyproline. ( Garrett, MR; Hung, LY; Mandel, NS; Wiessner, JH; Wille, DF, 2011)
"Experimental induction of hyperoxaluria by ethylene glycol (EG) administration is disapproved as it causes metabolic acidosis while the oral administration of chemically synthesized potassium oxalate (KOx) diet does not mimic our natural system."3.88Oral administration of oxalate-enriched spinach extract as an improved methodology for the induction of dietary hyperoxaluric nephrocalcinosis in experimental rats. ( Albert, A; Ganesan, D; Govindan Sadasivam, S; Mariaraj Sivakumar, S; Paul, E; Ponnusamy, S; Prabhakaran, R; Tiwari, V, 2018)
"Nephrolithiasis is one of the most common urinary tract disorders, with the majority of kidney stones composed of calcium oxalate (CaOx)."3.83Sulfate and thiosulfate inhibit oxalate transport via a dPrestin (Slc26a6)-dependent mechanism in an insect model of calcium oxalate nephrolithiasis. ( Anderson, JB; Cabrero, P; Dow, JA; Gallo, CJ; Hirata, T; Landry, GM; Romero, MF, 2016)
"The use of hydroxyproline (HP) to generate hyperoxaluria in the rat is a problem because it is impossible to separate the effect of oxalate on renal injury from the effects of HP and the large array of metabolic intermediates formed when HP is converted to oxalate."3.77Improved methodology to induce hyperoxaluria without treatment using hydroxyproline. ( Garrett, MR; Hung, LY; Mandel, NS; Wiessner, JH; Wille, DF, 2011)
"Empagliflozin treatment started from day 0 of oxalate feeding had no effect on the decline of glomerular filtration rate, crystal deposition, blood urea nitrogen or serum creatinine levels on day 7 and 14."1.46Sodium glucose transporter-2 inhibition has no renoprotective effects on non-diabetic chronic kidney disease. ( Anders, HJ; Ma, Q; Steiger, S, 2017)
"Urolithiasis is a multifaceted process, progressing from urine supersaturation to the formation of mature renal calculi."1.39Molecular mechanisms involved in the protective effect of the chloroform extract of Selaginella lepidophylla (Hook. et Grev.) Spring in a lithiasic rat model. ( Christophe, BO; Estela, MC; Juanita, NM; Mirian, EC, 2013)

Research

Studies (14)

TimeframeStudies, this research(%)All Research%
pre-19901 (7.14)18.7374
1990's2 (14.29)18.2507
2000's2 (14.29)29.6817
2010's8 (57.14)24.3611
2020's1 (7.14)2.80

Authors

AuthorsStudies
Sayed, AA1
Fahmy, SR1
Soliman, AM1
Mohamed, DM1
Ma, Q1
Steiger, S1
Anders, HJ2
Albert, A2
Tiwari, V1
Paul, E2
Ponnusamy, S2
Ganesan, D1
Prabhakaran, R1
Mariaraj Sivakumar, S1
Govindan Sadasivam, S1
Mishra, SR1
Vignesh, AG1
Sivakumar, SM1
Sivasamy, G1
Sadasivam, SG1
Mirian, EC1
Juanita, NM1
Christophe, BO1
Estela, MC1
Weljie, AM1
Meerlo, P1
Goel, N1
Sengupta, A1
Kayser, MS1
Abel, T1
Birnbaum, MJ1
Dinges, DF1
Sehgal, A1
Landry, GM1
Hirata, T1
Anderson, JB1
Cabrero, P1
Gallo, CJ1
Dow, JA1
Romero, MF1
Mulay, SR1
Eberhard, JN1
Pfann, V1
Marschner, JA1
Darisipudi, MN1
Daniel, C1
Romoli, S1
Desai, J1
Grigorescu, M1
Kumar, SV1
Rathkolb, B1
Wolf, E1
Hrabě de Angelis, M1
Bäuerle, T1
Dietel, B1
Wagner, CA1
Amann, K1
Eckardt, KU1
Aronson, PS1
Knauf, F1
Wiessner, JH1
Garrett, MR1
Hung, LY1
Wille, DF1
Mandel, NS1
Hossain, RZ1
Ogawa, Y1
Morozumi, M1
Hokama, S1
Uchida, A1
Sugaya, K1
Yasui, T1
Fujita, K1
Sasaki, S1
Sato, M1
Sugimoto, M1
Hirota, S1
Kitamura, Y1
Nomura, S1
Kohri, K1
Hamamoto, DT1
Forkey, MW1
Davis, WL1
Kajander, KC1
Simone, DA1
Buck, AC1
Davies, RL1
Harrison, T1
Blakemore, WF1
Heath, MF1
Bennett, MJ1
Cromby, CH1
Pollitt, RJ1

Trials

1 trial available for oxalic acid and Disease Models, Animal

ArticleYear
Oxalic acid and diacylglycerol 36:3 are cross-species markers of sleep debt.
    Proceedings of the National Academy of Sciences of the United States of America, 2015, Feb-24, Volume: 112, Issue:8

    Topics: Animals; Biomarkers; Circadian Rhythm; Diglycerides; Disease Models, Animal; Energy Metabolism; Fema

2015

Other Studies

13 other studies available for oxalic acid and Disease Models, Animal

ArticleYear
Antinephrolithiatic activity of Ananas comosus extract against experimentally induced renal calculi in rats.
    Pakistan journal of pharmaceutical sciences, 2020, Volume: 33, Issue:4

    Topics: Ananas; Animals; Antioxidants; Disease Models, Animal; Kidney; Kidney Calculi; Male; Oxalic Acid; Ox

2020
Sodium glucose transporter-2 inhibition has no renoprotective effects on non-diabetic chronic kidney disease.
    Physiological reports, 2017, Volume: 5, Issue:7

    Topics: Animals; Benzhydryl Compounds; Blood Urea Nitrogen; Disease Models, Animal; Glomerular Filtration Ra

2017
Oral administration of oxalate-enriched spinach extract as an improved methodology for the induction of dietary hyperoxaluric nephrocalcinosis in experimental rats.
    Toxicology mechanisms and methods, 2018, Volume: 28, Issue:3

    Topics: Administration, Oral; Animals; Biomarkers; Crystallization; Disease Models, Animal; Ethylene Glycol;

2018
Designer probiotic Lactobacillus plantarum expressing oxalate decarboxylase developed using group II intron degrades intestinal oxalate in hyperoxaluric rats.
    Microbiological research, 2018, Volume: 215

    Topics: Alanine Racemase; Animals; Bacterial Proteins; Calcium; Calcium Oxalate; Carboxy-Lyases; Cell Adhesi

2018
Molecular mechanisms involved in the protective effect of the chloroform extract of Selaginella lepidophylla (Hook. et Grev.) Spring in a lithiasic rat model.
    Urolithiasis, 2013, Volume: 41, Issue:3

    Topics: Animals; Apoptosis; ATP-Binding Cassette Transporters; Chloroform; Creatinine; Disease Models, Anima

2013
Sulfate and thiosulfate inhibit oxalate transport via a dPrestin (Slc26a6)-dependent mechanism in an insect model of calcium oxalate nephrolithiasis.
    American journal of physiology. Renal physiology, 2016, Jan-15, Volume: 310, Issue:2

    Topics: Animals; Anion Transport Proteins; Antiporters; Calcium Oxalate; Disease Models, Animal; Drosophila

2016
Oxalate-induced chronic kidney disease with its uremic and cardiovascular complications in C57BL/6 mice.
    American journal of physiology. Renal physiology, 2016, 04-15, Volume: 310, Issue:8

    Topics: Animals; Disease Models, Animal; Fibroblast Growth Factor-23; Fibrosis; Hypertension; Mice; Mice, In

2016
Improved methodology to induce hyperoxaluria without treatment using hydroxyproline.
    Urological research, 2011, Volume: 39, Issue:5

    Topics: Animals; Crystallization; Disease Models, Animal; Hydroxyproline; Hyperoxaluria; Kidney; Male; Oxali

2011
Urinary response to an oxalic acid load is influenced by the timing of calcium loading in rats.
    The Journal of urology, 2005, Volume: 174, Issue:5

    Topics: Analysis of Variance; Animals; Calcium; Calcium Oxalate; Dietary Supplements; Disease Models, Animal

2005
Expression of bone matrix proteins in urolithiasis model rats.
    Urological research, 1999, Volume: 27, Issue:4

    Topics: Animals; Blood Urea Nitrogen; Blotting, Northern; Calcium Oxalate; Calcium-Binding Proteins; Choleca

1999
The role of pH and osmolarity in evoking the acetic acid-induced wiping response in a model of nociception in frogs.
    Brain research, 2000, Apr-17, Volume: 862, Issue:1-2

    Topics: Acetic Acid; Animals; Behavior, Animal; Buffers; Disease Models, Animal; Epidermis; Formates; Hydroc

2000
The protective role of eicosapentaenoic acid [EPA] in the pathogenesis of nephrolithiasis.
    The Journal of urology, 1991, Volume: 146, Issue:1

    Topics: Adult; Aged; Animals; Calcium; Disease Models, Animal; Drug Evaluation; Drug Evaluation, Preclinical

1991
Primary hyperoxaluria and L-glyceric aciduria in the cat.
    Journal of inherited metabolic disease, 1988, Volume: 11 Suppl 2

    Topics: Acute Kidney Injury; Animals; Cat Diseases; Cats; Disease Models, Animal; Female; Glyceric Acids; Hy

1988