Page last updated: 2024-10-19

oxalic acid and Chronic Kidney Failure

oxalic acid has been researched along with Chronic Kidney Failure in 46 studies

Oxalic Acid: A strong dicarboxylic acid occurring in many plants and vegetables. It is produced in the body by metabolism of glyoxylic acid or ascorbic acid. It is not metabolized but excreted in the urine. It is used as an analytical reagent and general reducing agent.
oxalic acid : An alpha,omega-dicarboxylic acid that is ethane substituted by carboxyl groups at positions 1 and 2.

Research Excerpts

ExcerptRelevanceReference
" With regard to the assembled results the authors recommend in addition to monitoring of vitamin C also monitoring of vitamin B6 in plasma during long-term administration of large doses of furosemide to patients with chronic renal failure as deficiency of these vitamins could develop."5.30[The effect of furosemide on urinary excretion of oxalic acid, vitamin C and vitamin B6 in chronic kidney failure]. ( Derzsiová, K; Mydlík, M; Rajnic, A; Zemberová, E, 1998)
"Among them, there were 50 ESRD patients and 23 healthy volunteers."1.72Plasma oxalic acid and cardiovascular risk in end-stage renal disease patients: a prospective, observational cohort pilot study. ( Driianska, V; Korol, L; Lebed, L; Snisar, L; Stepanova, N, 2022)
"Stone formation and nephrocalcinosis are both very common features of primary hyperoxaluria, yet the extent of each disease varies markedly between patients."1.42Nephrocalcinosis is a risk factor for kidney failure in primary hyperoxaluria. ( Bergstralh, EJ; Lieske, JC; Mehta, RA; Milliner, DS; Tang, X; Vrtiska, TJ, 2015)
"Enteric hyperoxaluria is a commonly seen adverse event after the jejunoileal bypass procedure."1.31Chronic renal failure secondary to oxalate nephropathy: a preventable complication after jejunoileal bypass. ( Hassan, I; Juncos, LA; Milliner, DS; Sarmiento, JM; Sarr, MG, 2001)
" With regard to the assembled results the authors recommend in addition to monitoring of vitamin C also monitoring of vitamin B6 in plasma during long-term administration of large doses of furosemide to patients with chronic renal failure as deficiency of these vitamins could develop."1.30[The effect of furosemide on urinary excretion of oxalic acid, vitamin C and vitamin B6 in chronic kidney failure]. ( Derzsiová, K; Mydlík, M; Rajnic, A; Zemberová, E, 1998)
"Patients with primary hyperoxaluria and chronic renal failure exhibited markedly greater plasma concentrations of oxalate."1.29Assay of plasma oxalate with soluble oxalate oxidase. ( Cerelli, E; Cosseddu, D; Linari, F; Marangella, M; Petrarulo, M; Vitale, C, 1994)
"Oxalic acid is an end product of metabolism, and no significant degradation of oxalate occurs in mammals."1.28Extrarenal clearance of oxalate increases with progression of renal failure in the rat. ( Costello, JF; Sadovnic, MJ; Smith, M; Stolarski, C, 1992)
"The role of vitamin B6 deficiency and ascorbate in the raised plasma oxalate concentrations of these patients was evaluated."1.28Plasma oxalate levels rise in hemodialysis patients despite increased oxalate removal. ( Costello, JF; Cottington, EM; Sadovnic, MJ, 1991)
"We conclude that pyridoxine deficiency does not contribute significantly to hyperoxalaemia in patients receiving dialysis and that 100 mg of pyridoxine daily is insufficient to reduce oxalate generation by a pharmacological action on glycine transamination."1.28Effect of pyridoxine supplementation on plasma oxalate concentrations in patients receiving dialysis. ( Channon, SM; Laker, MK; Parkinson, IS; Sheldon, WS; Tomson, CR; Ward, MK, 1989)
"This case illustrates that despite recurrence of oxalate stones in the allograft, satisfactory renal function can be maintained by careful follow-up and appropriate interventions."1.27Successful renal transplantation in hyperoxaluria. A report of two cases. ( Alison, DV; Curtis, J; Diethelm, AG; Luke, RG; Whelchel, JD, 1983)
"Age at the time ESRD develops, mental status, psychosocial status and the primary renal disease must be taken into consideration when contemplating the optimal therapeutic modality for the pediatric patient with ESRD."1.27Choosing a treatment modality for the infant, child and adolescent with endstage renal disease. ( Fine, RN, 1987)
"In the control of serum oxalate in chronic renal failure dietary protein restriction is effective in the pre-dialysis patient whereas both CAPD and haemodialysis are relatively inefficient in end-stage renal failure."1.27Serum oxalate in chronic renal failure. ( Borland, WW; Macdougall, AI; Payton, CD; Simpson, K, 1987)

Research

Studies (46)

TimeframeStudies, this research(%)All Research%
pre-199024 (52.17)18.7374
1990's14 (30.43)18.2507
2000's4 (8.70)29.6817
2010's1 (2.17)24.3611
2020's3 (6.52)2.80

Authors

AuthorsStudies
Kojima, F1
Gandhi, JS1
Matsuzaki, I1
Iba, A1
Collier, S1
Yoshikawa, T1
Kinoshita, Y1
Warigaya, K1
Fujimoto, M1
Kuroda, N1
Morii, E1
Hara, I1
Murata, SI1
Amin, MB1
Kletzmayr, A1
Ivarsson, ME1
Leroux, JC1
Stepanova, N1
Driianska, V1
Korol, L1
Snisar, L1
Lebed, L1
Tang, X1
Bergstralh, EJ1
Mehta, RA1
Vrtiska, TJ1
Milliner, DS2
Lieske, JC1
BRUSCAGLI, G1
DINI, S1
TERZANI, E1
Ogawa, Y1
Machida, N1
Jahana, M1
Gakiya, M1
Chinen, Y1
Oda, M1
Morozumi, M1
Sugaya, K1
Mydlík, M5
Derzsiová, K5
Whelchel, JD1
Alison, DV1
Luke, RG1
Curtis, J1
Diethelm, AG1
Balcke, P6
Schmidt, P4
Zazgornik, J5
Kopsa, H4
Haubenstock, A1
Barsotti, G1
Cristofano, C1
Morelli, E1
Meola, M1
Lupetti, S1
Giovannetti, S1
Chesney, RW1
Friedman, AL1
Breed, AL1
Langer, LO1
Gilbert, EF1
Opitz, JM1
Deutsch, E2
Petrarulo, M1
Cerelli, E1
Marangella, M1
Cosseddu, D1
Vitale, C1
Linari, F1
France, NC1
Holland, PT1
Wallace, MR1
Pribylincová, V1
Reznícek, J1
Svác, J1
Dlhopolcek, P1
Zemberová, E2
Rajnic, A1
Cochat, P1
Hassan, I1
Juncos, LA1
Sarmiento, JM1
Sarr, MG1
Costello, JF2
Smith, M1
Stolarski, C1
Sadovnic, MJ2
Scheinman, JI1
Polinsky, MS1
Dunn, S1
Kaiser, BA1
Schulman, SL1
Wolfson, BJ1
Elfenbein, IB1
Baluarte, HJ1
Cottington, EM1
McConnell, KN1
Rolton, HA1
Modi, KS1
Macdougall, AI2
Chen, SM1
Chen, TW1
Lee, YH1
Chu, WY1
Young, TK1
Schillinger, F1
Montagnac, R1
Milcent, T1
Ogata, K1
Tomson, CR1
Channon, SM1
Parkinson, IS1
Sheldon, WS1
Ward, MK1
Laker, MK1
Proia, AD1
Brinn, NT1
Frosch, M1
Kuwertz-Bröking, E1
Bulla, M1
von Bassewitz, DB1
Leusmann, DB1
Ono, K1
Ono, H1
Ono, T1
Kikawa, K1
Oh, Y1
Fine, RN1
Dorhout Mees, EJ1
Boer, P1
Borland, WW1
Payton, CD1
Simpson, K1
Schumacher, HR1
Reginato, AJ1
Pullman, S1
Biesenbach, G1
Kaiser, W1
Stockenhuber, F1
Yamauchi, A1
Fujii, M1
Shirai, D1
Mikami, H1
Okada, A1
Imai, E1
Ando, A1
Orita, Y1
Kamada, T1
Worcester, EM1
Nakagawa, Y1
Bushinsky, DA1
Coe, FL1
Mitwalli, A1
Oreopoulos, DG1
Kasidas, GP1
Rose, GA1
Pru, C1
Eaton, J1
Kjellstrand, C1
Ahmad, S1
Hatch, M1

Reviews

3 reviews available for oxalic acid and Chronic Kidney Failure

ArticleYear
Investigational Therapies for Primary Hyperoxaluria.
    Bioconjugate chemistry, 2020, 07-15, Volume: 31, Issue:7

    Topics: Cell- and Tissue-Based Therapy; Disease Progression; Genetic Therapy; Humans; Hyperoxaluria; Kidney

2020
Primary hyperoxaluria type 1.
    Kidney international, 1999, Volume: 55, Issue:6

    Topics: Child; Female; Glycolates; Humans; Hyperoxaluria, Primary; Kidney Failure, Chronic; Kidney Transplan

1999
Hyperoxaluria and hyperoxalemia: one more concern for the nephrologist.
    The International journal of artificial organs, 1985, Volume: 8, Issue:2

    Topics: Ascorbic Acid; Humans; Kidney; Kidney Failure, Chronic; Kidney Transplantation; Metabolism, Inborn E

1985

Trials

1 trial available for oxalic acid and Chronic Kidney Failure

ArticleYear
Peritoneal clearance and peritoneal transfer of oxalic acid, vitamin C, and vitamin B6 during continuous ambulatory peritoneal dialysis.
    Artificial organs, 1998, Volume: 22, Issue:9

    Topics: Adult; Ascorbic Acid; Dietary Proteins; Diuretics; Female; Furosemide; Humans; Kidney Failure, Chron

1998

Other Studies

42 other studies available for oxalic acid and Chronic Kidney Failure

ArticleYear
Comprehensive Clinicopathologic Analyses of Acquired Cystic Disease-associated Renal Cell Carcinoma With Focus on Adverse Prognostic Factors and Metastatic Lesions.
    The American journal of surgical pathology, 2020, Volume: 44, Issue:8

    Topics: Adult; Aged; Biomarkers, Tumor; Carcinoma, Renal Cell; Crystallization; Female; Humans; Japan; Kidne

2020
Plasma oxalic acid and cardiovascular risk in end-stage renal disease patients: a prospective, observational cohort pilot study.
    The Korean journal of internal medicine, 2022, Volume: 37, Issue:1

    Topics: Atherosclerosis; Cardiovascular Diseases; Cytokines; Female; Heart Disease Risk Factors; Humans; Kid

2022
Nephrocalcinosis is a risk factor for kidney failure in primary hyperoxaluria.
    Kidney international, 2015, Volume: 87, Issue:3

    Topics: Adolescent; Adult; Age of Onset; Child; Child, Preschool; Citric Acid; Female; Humans; Hyperoxaluria

2015
[Chronic experimental nephropathy induced by oxalic acid and the influence of renal hyperfunction on it].
    Archivio "de Vecchi" per l'anatomia patologica e la medicina clinica, 1962, Volume: 37

    Topics: Humans; Kidney; Kidney Diseases; Kidney Failure, Chronic; Nephrectomy; Oxalates; Oxalic Acid; Renal

1962
Major factors modulating the serum oxalic acid level in hemodialysis patients.
    Frontiers in bioscience : a journal and virtual library, 2004, Sep-01, Volume: 9

    Topics: Aged; Ascorbic Acid; Citric Acid; Creatinine; Female; Glycolates; Humans; Kidney Failure, Chronic; M

2004
Oxalic Acid as a uremic toxin.
    Journal of renal nutrition : the official journal of the Council on Renal Nutrition of the National Kidney Foundation, 2008, Volume: 18, Issue:1

    Topics: Adult; Ascorbic Acid; Atherosclerosis; Creatinine; Female; Glomerulonephritis; Humans; Kidney Diseas

2008
Successful renal transplantation in hyperoxaluria. A report of two cases.
    Transplantation, 1983, Volume: 35, Issue:2

    Topics: Adult; Biopsy; Female; Follow-Up Studies; Graft Survival; Humans; Kidney; Kidney Calculi; Kidney Fai

1983
Ascorbic acid aggravates secondary hyperoxalemia in patients on chronic hemodialysis.
    Annals of internal medicine, 1984, Volume: 101, Issue:3

    Topics: Adult; Ascorbic Acid; Ascorbic Acid Deficiency; Female; Humans; Kidney Failure, Chronic; Male; Oxala

1984
Serum oxalic acid in uremia: effect of a low-protein diet supplemented with essential amino acids and ketoanalogues.
    Nephron, 1984, Volume: 38, Issue:1

    Topics: Amino Acids, Essential; Calcium Carbonate; Creatinine; Dietary Proteins; Female; Humans; Keto Acids;

1984
Renal failure with hypercalcemia, renal stones, multiple pathologic fractures, and growth failure.
    American journal of medical genetics, 1983, Volume: 14, Issue:1

    Topics: Child, Preschool; Female; Fractures, Spontaneous; Growth Disorders; Humans; Hypercalcemia; Kidney Ca

1983
Reduction of elevated plasma oxalic acid by pyridoxine therapy in patients on RDT.
    Proceedings of the European Dialysis and Transplant Association. European Dialysis and Transplant Association, 1983, Volume: 19

    Topics: Dose-Response Relationship, Drug; Humans; Kidney Failure, Chronic; Oxalates; Oxalic Acid; Pyridoxine

1983
Secondary hyperoxalemia in chronic renal failure.
    The International journal of artificial organs, 1982, Volume: 5, Issue:3

    Topics: Blood; Calcinosis; Calcium Oxalate; Creatinine; Humans; Kidney Failure, Chronic; Oxalates; Oxalic Ac

1982
[Secondary oxalosis in chronic renal insufficiency].
    Zeitschrift fur Urologie und Nephrologie, 1982, Volume: 75, Issue:6

    Topics: Adult; Creatinine; Female; Humans; Kidney Failure, Chronic; Male; Middle Aged; Oxalates; Oxalic Acid

1982
Assay of plasma oxalate with soluble oxalate oxidase.
    Clinical chemistry, 1994, Volume: 40, Issue:11 Pt 1

    Topics: Adolescent; Adsorption; Adult; Ascorbic Acid; Benzenesulfonates; Blood Proteins; Charcoal; Child; Ch

1994
Contribution of dialysis to endogenous oxalate production in patients with chronic renal failure.
    Clinical chemistry, 1994, Volume: 40, Issue:8

    Topics: Acetates; Bicarbonates; Buffers; Dialysis Solutions; Female; Glycolates; Humans; Indicator Dilution

1994
[Urinary oxalic acid excretion in chronic kidney failure and after kidney transplantation].
    Vnitrni lekarstvi, 1996, Volume: 42, Issue:12

    Topics: Adult; Ascorbic Acid; Creatinine; Female; Humans; Kidney Failure, Chronic; Kidney Transplantation; M

1996
[The effect of furosemide on urinary excretion of oxalic acid, vitamin C and vitamin B6 in chronic kidney failure].
    Vnitrni lekarstvi, 1998, Volume: 44, Issue:3

    Topics: Adult; Ascorbic Acid; Diuretics; Female; Furosemide; Humans; Kidney Failure, Chronic; Male; Middle A

1998
Renal replacement therapy and secondary hyperoxalemia in chronic renal failure.
    Kidney international. Supplement, 2001, Volume: 78

    Topics: Adult; Ascorbic Acid; Female; Hemodiafiltration; Humans; Kidney Failure, Chronic; Male; Middle Aged;

2001
Chronic renal failure secondary to oxalate nephropathy: a preventable complication after jejunoileal bypass.
    Mayo Clinic proceedings, 2001, Volume: 76, Issue:7

    Topics: Aftercare; Causality; Chronic Disease; Humans; Hyperoxaluria; Jejunoileal Bypass; Kidney Failure, Ch

2001
Extrarenal clearance of oxalate increases with progression of renal failure in the rat.
    Journal of the American Society of Nephrology : JASN, 1992, Volume: 3, Issue:5

    Topics: Animals; Biological Transport; Bone and Bones; Feces; Intestinal Mucosa; Kidney Failure, Chronic; Ma

1992
Primary hyperoxaluria: therapeutic strategies for the 90's.
    Kidney international, 1991, Volume: 40, Issue:3

    Topics: Adult; Alanine Transaminase; Algorithms; Calcium Oxalate; Child; Combined Modality Therapy; Humans;

1991
Combined liver-kidney transplantation in a child with primary hyperoxaluria.
    Pediatric nephrology (Berlin, Germany), 1991, Volume: 5, Issue:3

    Topics: Child, Preschool; Graft Rejection; Humans; Hyperoxaluria, Primary; Kidney Failure, Chronic; Kidney T

1991
Plasma oxalate levels rise in hemodialysis patients despite increased oxalate removal.
    Journal of the American Society of Nephrology : JASN, 1991, Volume: 1, Issue:12

    Topics: Alanine Transaminase; Ascorbic Acid; Erythrocytes; Humans; Intestinal Absorption; Kidney Failure, Ch

1991
Plasma oxalate in patients with chronic renal failure receiving continuous ambulatory peritoneal dialysis or hemodialysis.
    American journal of kidney diseases : the official journal of the National Kidney Foundation, 1991, Volume: 18, Issue:4

    Topics: Adult; Aged; Calcium; Creatinine; Female; Humans; Kidney Failure, Chronic; Male; Middle Aged; Oxalat

1991
Renal excretion of oxalate in patients with chronic renal failure or nephrolithiasis.
    Journal of the Formosan Medical Association = Taiwan yi zhi, 1990, Volume: 89, Issue:8

    Topics: Adult; Aged; Calcium; Humans; Kidney; Kidney Calculi; Kidney Failure, Chronic; Male; Metabolic Clear

1990
[Hyperoxalemia and secondary oxalosis of chronic renal insufficiency].
    Nephrologie, 1990, Volume: 11, Issue:4

    Topics: Humans; Kidney; Kidney Failure, Chronic; Oxalates; Oxalic Acid

1990
Clinicopathological study of kidneys from patients on chronic dialysis.
    Kidney international, 1990, Volume: 37, Issue:5

    Topics: Adolescent; Adult; Body Weight; Cell Division; Child; Child, Preschool; Female; Humans; Hyperplasia;

1990
Effect of pyridoxine supplementation on plasma oxalate concentrations in patients receiving dialysis.
    European journal of clinical investigation, 1989, Volume: 19, Issue:2

    Topics: Aspartate Aminotransferases; Erythrocytes; Humans; Kidney Failure, Chronic; Oxalates; Oxalic Acid; P

1989
Identification of calcium oxalate crystals using alizarin red S stain.
    Archives of pathology & laboratory medicine, 1985, Volume: 109, Issue:2

    Topics: Animals; Anthraquinones; Calcium Carbonate; Calcium Oxalate; Calcium Phosphates; Ethylene Glycol; Et

1985
[Type I oxalosis in childhood--studies within the scope of terminal renal failure in the child].
    Klinische Wochenschrift, 1989, Nov-17, Volume: 67, Issue:22

    Topics: Adolescent; Child; Child, Preschool; Female; Follow-Up Studies; Humans; Hyperoxaluria; Hyperoxaluria

1989
Effect of vitamin C supplementation on renal oxalate deposits in five-sixths nephrectomized rats.
    Nephron, 1989, Volume: 51, Issue:4

    Topics: Animals; Ascorbic Acid; Hyperoxaluria, Primary; Kidney Failure, Chronic; Kidney Tubules; Male; Nephr

1989
Choosing a treatment modality for the infant, child and adolescent with endstage renal disease.
    Blood purification, 1987, Volume: 5, Issue:1

    Topics: Adolescent; Age Factors; Anorexia; Bone Diseases; Child; Child, Preschool; Cystinosis; Glomeruloscle

1987
Plasma oxalate in chronic renal failure and normal subjects: methodological problems.
    Nephron, 1988, Volume: 48, Issue:3

    Topics: Humans; Kidney Failure, Chronic; Oxalates; Oxalic Acid; Reference Values

1988
Serum oxalate in chronic renal failure.
    Nephron, 1987, Volume: 45, Issue:2

    Topics: Adult; Aged; Creatinine; Dietary Proteins; Female; Humans; Kidney Failure, Chronic; Male; Middle Age

1987
Synovial fluid oxalate deposition complicating rheumatoid arthritis with amyloidosis and renal failure. Demonstration of intracellular oxalate crystals.
    The Journal of rheumatology, 1987, Volume: 14, Issue:2

    Topics: Amyloidosis; Arthritis, Rheumatoid; Ascorbic Acid; Humans; Kidney Failure, Chronic; Male; Middle Age

1987
Myocardial calcinosis associated with hemodialysis.
    The American journal of cardiology, 1987, Aug-01, Volume: 60, Issue:4

    Topics: Adult; Ascorbic Acid; Calcinosis; Calcium Oxalate; Cardiomyopathies; Humans; Kidney Failure, Chronic

1987
Plasma concentration and peritoneal clearance of oxalate in patients on continuous ambulatory peritoneal dialysis (CAPD).
    Clinical nephrology, 1986, Volume: 25, Issue:4

    Topics: Adolescent; Adult; Aged; Blood Urea Nitrogen; Dietary Proteins; Female; Humans; Kidney Failure, Chro

1986
Evidence that serum calcium oxalate supersaturation is a consequence of oxalate retention in patients with chronic renal failure.
    The Journal of clinical investigation, 1986, Volume: 77, Issue:6

    Topics: Adult; Aged; Calcium Oxalate; Chromatography, High Pressure Liquid; Creatinine; Female; Humans; Kidn

1986
[Oxalic acid metabolism in chronic renal failure].
    Wiener klinische Wochenschrift. Supplementum, 1985, Volume: 160

    Topics: Ascorbic Acid; Aspartate Aminotransferases; Combined Modality Therapy; Erythrocytes; Glycolates; Hum

1985
Measurement of plasma oxalate in healthy subjects and in patients with chronic renal failure using immobilised oxalate oxidase.
    Clinica chimica acta; international journal of clinical chemistry, 1986, Jan-15, Volume: 154, Issue:1

    Topics: Adult; Ascorbic Acid; Creatinine; Enzymes, Immobilized; Female; Humans; Hydrogen-Ion Concentration;

1986
Vitamin C intoxication and hyperoxalemia in chronic hemodialysis patients.
    Nephron, 1985, Volume: 39, Issue:2

    Topics: Adolescent; Adult; Aged; Ascorbic Acid; Child; Humans; Kidney Failure, Chronic; Middle Aged; Oxalate

1985
Hyperoxalemia in renal failure and the role of hemoperfusion and hemodialysis in primary oxalosis.
    Nephron, 1985, Volume: 41, Issue:3

    Topics: Adult; Creatinine; Female; Hemoperfusion; Humans; Kidney Failure, Chronic; Male; Oxalates; Oxalic Ac

1985