oxalates and Eye-Diseases

The authors reported ten cases of familial nephropathy (two cystinosis, three Senior and Loken syndrome, one Alport's syndrome and four Oxalosis) associated to ocular manifestations. Aetiologic diagnosis was known from ocular symptoms in five cases (all cases of cystinosis and Senior and Loken syndrome). The authors undertook this study to analyse the value of ocular manifestations in determining the right aetiologic diagnosis in familial nephropathies. The results of this study showed that ocular manifestations are helpful for aetiologic diagnosis in the first diseases. Indeed, corneal injury is synonym of cystinosis and retinitis pigmentosa is usually associated with Senior and Loken syndrome. In Alport's syndrome, ocular manifestations: antcrior lenticonus cataractous and perimacular white points only have orientation value in the diagnosis of this disease. Oxalosis ocular manifestations which consist of retinal oxalate deposits appear late and are concomitant to familial renal insufficiency. They cannot help in the diagnostic search.

Topics: Adolescent; Child; Corneal Diseases; Cystinosis; Eye Diseases; Humans; Kidney Diseases; Nephritis, Hereditary; Oxalates; Renal Insufficiency; Retinal Diseases; Retinitis Pigmentosa

Topics: Child; Eye; Eye Diseases; Humans; Kidney Failure, Chronic; Male; Oxalates; Renal Dialysis

Ocular involvement from primary hyperoxaluria developed in one infant and one teenaged patient. Autopsy procedures in the first case used special histopathologic staining techniques to demonstrate a wider deposition of calcium oxalate crystals within the eye than was previously suspected. Clinical photographs and fluorescein angiograms in the older patient demonstrated a widespread retinal distribution of crystals with a periarterial predilection. This patient also demonstrated a unique acquired black macular lesion.

Topics: Adolescent; Eye Diseases; Female; Fluorescein Angiography; Humans; Infant; Male; Metabolism, Inborn Errors; Oxalates; Retina

Topics: Animals; Cortisone; Diphenhydramine; Edema; Eye Diseases; Female; Histamine; Male; Oxalates; Plant Extracts; Plant Poisoning; Plants; Rabbits; Rats; Tongue Diseases; Trypsin

Topics: Animals; Epithelium; Eye; Eye Diseases; Lens, Crystalline; Naphthalenes; Oxalates; Rabbits; Retina; Retinal Pigments; Vitreous Body