oxalates and Bone-Diseases

Topics: Adult; Bone Diseases; Bone Resorption; Calcinosis; Fingers; Giant Cells; Hand; Humans; Hyperoxaluria, Primary; Male; Middle Aged; Osteosclerosis; Oxalates; Radiography

Topics: Acute Kidney Injury; Adult; Bone Diseases; Humans; Joint Diseases; Kidney; Male; Nephrocalcinosis; Oxalates; Renal Dialysis; Time Factors

The factors involved in choosing a treatment modality for the infant, child and adolescent with endstage renal disease (ESRD) are different than those utilized when counseling an adult patient. Age at the time ESRD develops, mental status, psychosocial status and the primary renal disease must be taken into consideration when contemplating the optimal therapeutic modality for the pediatric patient with ESRD.

Topics: Adolescent; Age Factors; Anorexia; Bone Diseases; Child; Child, Preschool; Cystinosis; Glomerulosclerosis, Focal Segmental; Growth Disorders; Humans; Infant; Kidney Failure, Chronic; Kidney Transplantation; Oxalates; Oxalic Acid; Peritoneal Dialysis; Peritoneal Dialysis, Continuous Ambulatory; Psychology; Wilms Tumor

Clinical, radiographic and scintigraphic abnormalities in primary oxalosis of a 52 years old female are demonstrated. Severe oxalosis-nephropathy and oxalosis-arthropathy/enthesiopathy are shown. For the first time an intense myocardial uptake of 99 m Tc-HDP and 99 m Tc-MDP is described in connection with oxalosis. It is suggested that in the appropriate clinical setting this pattern may be suggestive of oxalosis-cardiomyopathy. Review of literature.

Topics: Arthritis; Bone Diseases; Cardiomyopathies; Diphosphonates; Female; Humans; Hyperoxaluria; Kidney Calculi; Middle Aged; Oxalates; Technetium; Technetium Tc 99m Medronate

The use of new dialythic technics has increased the survival times for patients with primary hyperoxaluria. From here the possibility of visualizing X-rays signs specific of oxalosis besides the typical bone lesions of hyperparathyroidism secondary to chronic renal failure. Recent hysto-pathological studies allowed to correlate such radiological findings to a new pathogenetical mechanism that would be responsible of the bone lesion specific for oxalosis and that might be caused by the presence of reabsorption cavities made up by macrophagic cells fagocyting cristals.

Topics: Adolescent; Bone and Bones; Bone Diseases; Cartilage, Articular; Crystallization; Humans; Hyperparathyroidism; Kidney Failure, Chronic; Male; Nephrocalcinosis; Oxalates; Radiography; Renal Dialysis; Urinary Calculi

Topics: Adolescent; Bone Diseases; Femur; Humans; Kidney Calculi; Kidney Failure, Chronic; Male; Oxalates; Radiography; Renal Dialysis; Sclerosis

A 13-year-old boy with primary hyperoxaluria and a successful renal allograft developed symptomatic bone disease, hypercalcemia, and hypercalciuria. Transiliac bone biopsy revealed calcium oxalate crystals in the marrow within mononuclear phagocytes and multinucleated giant cells. Deep resorption bays were seen adjacent to these crystal-cell aggregates. Serum 1,25-(OH)2-vitamin D (calcitriol) and iPTH concentrations were low or normal. We suggest that hypercalcemia results from macrophage-mediated bone resorption initiated by Ca oxalate crystal deposition.

Topics: Adolescent; Bone Diseases; Bone Resorption; Calcium Oxalate; Humans; Hypercalcemia; Kidney Transplantation; Male; Oxalates; Oxalic Acid

Oxalosis involving bone secondary to prolonged chronic renal failure and long-term dialysis occurred in a living patient. The cystalline deposit in the small fragment of bone was identified by electron diffraction.

Topics: Adult; Birefringence; Bone and Bones; Bone Diseases; Calcium; Female; Humans; Kidney Failure, Chronic; Microscopy, Electron; Oxalates

Topics: Adolescent; Bone Diseases; Calcinosis; Calcium; Humans; Hydroxyapatites; Hyperparathyroidism, Secondary; Kidney Diseases; Male; Metabolic Diseases; Oxalates; Urinary Calculi; Urography

Topics: Adolescent; Bone and Bones; Bone Diseases; Calcium; Female; Histocytochemistry; Humans; Kidney Failure, Chronic; Male; Metabolic Diseases; Oxalates