oxalates and Avitaminosis

Topics: Amino Acids; Avitaminosis; Biotransformation; Glycine; Humans; Oxalates; Oxalic Acid; Oxidation-Reduction; Oxygen Inhalation Therapy; Xylitol

A review of the problems associated with extensive jejunoileal bypass for morbid obesity in a series of 175 carefully selected patients is presented. Five postoperative deaths occurred (3%). Nonfatal complications occurred in 21%, with wound infections (14 patients) being the most common. Good results marked by weight reduction to the range of ideal weight without significant electrolyte or metabolic aberrations was observed in 82% of the patients receiving the current dimensional modificatiom of end-to-end jejunoileal bypass (30 cm to 20cm). An additional 13% had fair results and only 5% had poor results. There were six deaths during follow-up: liver failure in four patients (secondary to alcohol abuse in two), myocardial infarction in one, and one from unknown causes. Bypass reversal was necessary for refractory liver failure in three patients (two from alcohol abuse), and for persistent diarrhea with secondary electrolyte depletion in two patients. One of these patients was complicated by severe emotional instability. This experience suggests that the majority of carefully selected patients will have a good response to jejunoileal bypass.

Topics: Adolescent; Adult; Anemia; Avitaminosis; Body Weight; Cholelithiasis; Diarrhea; Electrolytes; Fatty Liver; Female; Follow-Up Studies; Gout; Humans; Hypoproteinemia; Ileum; Jejunum; Kidney Calculi; Liver Diseases; Male; Middle Aged; Obesity; Oxalates; Postoperative Complications

Topics: Adolescent; Adult; Anemia, Hypochromic; Avitaminosis; Cholelithiasis; Diarrhea; Female; Follow-Up Studies; Gout; Humans; Ileum; Jejunum; Kidney Calculi; Liver Diseases; Male; Middle Aged; Obesity; Oxalates; Postoperative Complications

Topics: Animals; Avitaminosis; Calcium; Chromatin; Cytoplasm; Endoplasmic Reticulum; Epithelial Cells; Golgi Apparatus; Kidney; Kidney Tubules; Lipids; Male; Microscopy, Electron; Mitochondria; Nephrocalcinosis; Oxalates; Pyridoxine; Rats; Rats, Inbred Strains; Ribosomes; Time Factors

Topics: Animals; Avitaminosis; Biological Transport; Calcium Oxalate; Hematuria; Oxalates; Rats; Sulfathiazole; Sulfathiazoles; Vitamin B 6; Vitamin B Deficiency; Vitamins