oxalates has been researched along with Arthritis--Rheumatoid* in 3 studies
3 other study(ies) available for oxalates and Arthritis--Rheumatoid
| Article | Year |
|---|---|
Evaluation of [(89)Zr]-Oxalate as a PET Tracer in Inflammation, Tumor, and Rheumatoid Arthritis Models.
To obtain an additional pharmacological agent for the diagnosis of inflammation, we investigated the medical use of (89)Zr-oxalate as a positron emission tomography (PET) probe for the in vivo imaging of inflammation and compared its efficacy to that of 2-deoxy-2-[(18)F]fluoro-d-glucose ([(18)F]FDG) and sodium [(18)F]fluoride. (89)Zr-oxalate exhibited observable higher uptake in a macrophage cell line than in tumor cells. The inflammatory lesions and tumors were clearly visualized by PET imaging and autoradiography using (89)Zr-oxalate. Compared to [(18)F]FDG and sodium [(18)F]fluoride, (89)Zr-oxalate demonstrated a high selectivity index to the tumor at an early time point after injection and to inflammation at a delayed time point after injection (24 h). Through histological examination, large numbers of macrophages and neutrophils were observed in the tumor lesions with the highest (89)Zr-oxalate uptake. In a rheumatoid arthritis (RA) mouse model, (89)Zr-oxalate demonstrated a high level of accumulation in inflammatory lesions. (89)Zr-oxalate is a new strategic tool for tumor imaging and inflammatory processes. Topics: Animals; Arthritis, Rheumatoid; Cell Line, Tumor; Fluorodeoxyglucose F18; Humans; Inflammation; Male; Mice; Oxalates; Positron-Emission Tomography; RAW 264.7 Cells | 2016 |
Synovial fluid oxalate deposition complicating rheumatoid arthritis with amyloidosis and renal failure. Demonstration of intracellular oxalate crystals.
A patient with quiescent rheumatoid arthritis, amyloidosis and chronic renal failure developed an inflamed knee. Intracellular bipyramidal crystals characteristic of oxalate were found and are suggested as the cause of the acute arthritis. Since the patient had been treated with vitamin C, this precursor of oxalate is proposed as a possible factor in the crystal deposition. Topics: Amyloidosis; Arthritis, Rheumatoid; Ascorbic Acid; Humans; Kidney Failure, Chronic; Male; Middle Aged; Oxalates; Oxalic Acid; Peritoneal Dialysis; Radiography; Synovial Fluid | 1987 |
[The effect of antiphlogistic and immunosuppressive agents on the immune reaction and the protein-nucleic acid metabolism in adjuvant arthritis and experimental rheumatic processes].
Topics: Alkylating Agents; Animals; Anti-Inflammatory Agents; Antibodies, Bacterial; Antibody Formation; Arthritis; Arthritis, Rheumatoid; Aspirin; Autoantibodies; Blood Proteins; Deoxyribonucleases; Freund's Adjuvant; Glucocorticoids; Histidine; Immune Adherence Reaction; Immunosuppressive Agents; Nitrogen Mustard Compounds; Nucleic Acids; Oxalates; Phenylacetates; Proteins; Rabbits; Rats; Rheumatoid Factor; Ribonucleases; Streptococcus; Succinates | 1973 |