oxalates and Anuria

Topics: Acute Kidney Injury; Anuria; Biopsy; Blood Urea Nitrogen; Child; Creatinine; Diagnosis, Differential; Duodenum; Endoscopy, Gastrointestinal; Humans; Intestinal Volvulus; Jejunum; Kidney; Male; Muscle Cramp; Oxalates; Treatment Outcome; Ultrasonography; Vomiting

Topics: Acute Disease; Acute Kidney Injury; Adenocarcinoma; Anuria; Ascorbic Acid; Humans; Infusions, Intravenous; Kidney Calculi; Male; Middle Aged; Oxalates; Prostatic Neoplasms

Topics: Acute Kidney Injury; Anuria; Diagnosis, Differential; Female; Humans; Infant; Kidney; Metabolism, Inborn Errors; Oxalates; X-Ray Diffraction

Histological and biochemical studies were carried out in a total of 300 patients who had died in the recovery room, and in rabbits, to investigate the frequency of deposits of calcium oxalte crystals in the kidneys, the influence of infusion therapy and the pathological significance of such deposits on the kidney tissue and on renal function. - Quite independent of any infusions, however, deposits of calcium oxalate crystals were found in the presence of kidney-specific diseases, in particular uraemia and anuric conditions. Xylitol infusions of 0.4 g/kg body weight or, in individual cases, of not more than 500 g total in 7 days, had no infllence on the appearance of calcium oxalate deposits. The blockage of the tubular system by the calcium oxalate deposits leads to a temporary reversible increase in serum urea and serum creatinine. With time, and uninfluenced by infusions, the deposits disappear out of the kidney again without having caused any organic renal damage. In the presence of a temporary excess of serum oxalate, the kidneys temporarily act like a cloaca.

Topics: Animals; Anuria; Autopsy; Calcium; Humans; Injections, Subcutaneous; Kidney; Kidney Calculi; Kidney Diseases; Oxalates; Parenteral Nutrition; Rabbits; Uremia; Xylitol

alpha-Chlorohydrin (I) is oxidatively metabolized to beta-chlorolactic acid (III) and oxalic acid (IV). Deposition of calcium oxalate within the renal tubules is responsible for the toxic effects of alpha-chlorohydrin and a similar action on the epididymis or epididymal blood vessels could initiate the formation of spermatocoeles from this and other male antifertility agents.. The oxidative metabolism of alpha-chlorohydrin and the chemical indu ction of spermatocoeles are described. Alpha-chlorohydrin was oxidative ly metabolized to beta-chlorolactic acid and oxalic acid. Deposition of calcium oxalate within the renal tubules was responsible for the toxic effects of alpha-chlorohydrin and a similar action on the epididymis or epididymal blood vessels may initiate the formation of spermatocoeles from this and other male antifertility agents.

Topics: Animals; Anuria; Diuresis; Kidney Failure, Chronic; Kidney Tubules; Lactates; Male; Oxalates; Rats; Spermatocele

Topics: Acidosis; Adolescent; Adult; Aged; Anuria; Bicarbonates; Calcium; Carbon Dioxide; Chemical and Drug Induced Liver Injury; Chemical Phenomena; Chemistry; Female; Humans; Hydrogen-Ion Concentration; Liver; Male; Middle Aged; Neurologic Manifestations; Nitrogen; Oxalates; Parenteral Nutrition; Solutions; Uremia; Uric Acid; Water-Electrolyte Balance; Xylitol

Topics: Acid-Base Equilibrium; Acute Disease; Aged; Anuria; Autopsy; Brain; Calcium; Dehydration; Glycols; Humans; Hydrogen-Ion Concentration; Kidney Tubules; Male; Oxalates; Peritoneal Dialysis; Poisoning

Topics: Acute Kidney Injury; Aged; Anuria; Calcium; Child; Female; Humans; Kidney Calculi; Kidney Tubules; Male; Methoxyflurane; Middle Aged; Oxalates; Postoperative Complications; Uremia

Topics: Adult; Anuria; Female; Humans; Kidney; Kidney Diseases; Metabolic Diseases; Metabolism, Inborn Errors; Myocarditis; Myocardium; Oxalates; Uremia

Two patients, aged 66 and 62 years, are described who suffered from unilateral anuria and contralateral stone formation due to primary oxalosis. The diagnosis was established by microscopical examination of necropsy material in the first patient and by renal biopsy in the second and was confirmed by chemical and x-ray investigation of tissues and calculi. The sequence of events leading to the rather sudden precipitation of oxalate in the tissues is discussed, and a tentative explanation for the unilateral anuria is offered.

Topics: Aged; Anuria; Biopsy; Geriatrics; Humans; Hyperoxaluria, Primary; Kidney Calculi; Kidney Glomerulus; Microscopy; Nephrectomy; Oxalates; Pathology

Topics: Anemia; Anemia, Hypochromic; Anuria; Hematologic Diseases; Humans; Hyperoxaluria; Kidney Calculi; Oxalates; Toxicology