oxadiazoles and Peptic-Ulcer

oxadiazoles has been researched along with Peptic-Ulcer* in 4 studies

Trials

1 trial(s) available for oxadiazoles and Peptic-Ulcer

Article	Year
[Determination of the effects of anti-ulcer agents by double-blind test based on the shrinkage rate of the x-ray niche: clinical evaluation of Pirecin, an anti-ulcer agent]. Nihon rinsho. Japanese journal of clinical medicine, 1971, Volume: 29, Issue:12 Topics: Adult; Aged; Clinical Trials as Topic; Evaluation Studies as Topic; Humans; Middle Aged; Oxadiazoles; Peptic Ulcer; Placebos; Radiography; Stomach	1971

Article

Year

[Determination of the effects of anti-ulcer agents by double-blind test based on the shrinkage rate of the x-ray niche: clinical evaluation of Pirecin, an anti-ulcer agent].

Nihon rinsho. Japanese journal of clinical medicine, 1971, Volume: 29, Issue:12

Topics: Adult; Aged; Clinical Trials as Topic; Evaluation Studies as Topic; Humans; Middle Aged; Oxadiazoles; Peptic Ulcer; Placebos; Radiography; Stomach

1971

Other Studies

3 other study(ies) available for oxadiazoles and Peptic-Ulcer

Article	Year
A new class of ibuprofen derivatives with reduced gastrotoxicity. Journal of medicinal chemistry, 2001, Oct-11, Volume: 44, Issue:21 A new series of nonsteroidal antiinflammatory drugs (NSAIDs) obtained by linking ibuprofen to selected furoxan moieties and to related furazans were synthesized and tested for their antiinflammatory, antiaggregatory, and ulcerogenic properties. All the derivatives are endowed with antiinflammatory activity comparable to that of ibuprofen, but, unlike this drug, they display reduced acute gastrotoxicity. The masking of the ibuprofen-free carboxylic group seems to be principally at the basis of this reduced topical irritant action. The two furoxan derivatives 8 and 9 also trigger potent antiaggregatory effects, principally as a consequence of their NO-donor ability. Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Carrageenan; Cyclic N-Oxides; Edema; Gastric Mucosa; Humans; Ibuprofen; In Vitro Techniques; Male; Nitric Oxide Donors; Oxadiazoles; Peptic Ulcer; Platelet Aggregation Inhibitors; Rats; Rats, Wistar	2001
[Preliminary results of the use of propaxoline citrate in the therapy of gastroduodenal ulcer]. Minerva medica, 1972, Mar-14, Volume: 63, Issue:19 Topics: Adult; Aged; Anti-Inflammatory Agents; Duodenal Ulcer; Female; Humans; Male; Middle Aged; Oxadiazoles; Peptic Ulcer; Stomach Ulcer	1972
[Experimental observations on the use of propaxoline in therapy of gastroduodenal ulcer]. Bollettino della Societa italiana di biologia sperimentale, 1970, Dec-15, Volume: 46, Issue:23 Topics: Adult; Anti-Inflammatory Agents; Female; Humans; Male; Middle Aged; Oxadiazoles; Peptic Ulcer	1970