ovatodiolide has been researched along with Myocardial-Infarction* in 1 studies
1 other study(ies) available for ovatodiolide and Myocardial-Infarction
| Article | Year |
|---|---|
Identification of a Novel Theranostic Signature of Metabolic and Immune-Inflammatory Dysregulation in Myocardial Infarction, and the Potential Therapeutic Properties of Ovatodiolide, a Diterpenoid Derivative.
Myocardial infarction (MI) is a multifactorial global disease, recognized as one of the leading causes of cardiovascular morbidity and mortality. Timely and correct diagnoses and effective treatments could significantly reduce incidence of complications and improve patient prognoses. In this study, seven unconventional differentially expressed genes (DEGs) (MAN2A2, TNFRSF12A, SPP1, CSNK1D, PLAUR, PFKFB3, and CXCL16, collectively termed the MTSCPPC signature) were identified through integrating DEGs from six MI microarray datasets. The pathological and theranostic roles of the MTSCPPC signature in MI were subsequently analyzed. We evaluated interactions of the MTSCPPC signature with ovatodiolide, a bioactive compound isolated from Topics: Chemokine CXCL16; Databases, Genetic; Diterpenes; Gene Expression Profiling; Gene Regulatory Networks; Humans; Mannosidases; MicroRNAs; Molecular Docking Simulation; Myocardial Infarction; Osteopontin; Phosphofructokinase-2; Precision Medicine; Receptors, Urokinase Plasminogen Activator; Transcriptome; TWEAK Receptor | 2022 |