ouabain and Heart Failure

ouabain has been researched along with Heart Failure in 135 studies

Research

Studies (135)

Timeframe	Studies, this research(%)	All Research%
pre-1990	77 (57.04)	18.7374
1990's	32 (23.70)	18.2507
2000's	13 (9.63)	29.6817
2010's	9 (6.67)	24.3611
2020's	4 (2.96)	2.80

Authors

Authors	Studies
Bejček, J; Pavlíčková, VS; Rimpelová, S; Škubník, J	1
Botelho, AFM; Canta, GN; da Cruz, JPO; da Silva Ferreira, R; Fernandes, PBU; Lempek, MR; Mantovani, MM; Melo, MM; Silva, FLA; Veado, JCC	1
Banini, BA; Dashti, F; Jamshed, F; Mehal, WZ; Ouyang, X	1
Hamlyn, JM; Leenen, FHH; Wang, HW	1
Kaaja, RJ; Nicholls, MG	1
Cheng, F; Eng, C; Fang, J; Handy, DE; Hill, DE; Hou, Y; Huang, J; Liu, C; Loscalzo, J; Lu, W; Vidal, M; Wang, R; Yang, Y; Zhao, Y	1
Baecher, S; Fassnacht, M; Kroiss, M; Vogeser, M	1
Fernandes, AA; Padilha, AS; Silveira, EA; Siman, FD; Stefanon, I; Vassallo, DV	1
Alfieri, O; Bignami, E; Botticelli, IM; Casamassima, N; Frati, E; Lanzani, C; Manunta, P; Messaggio, E; Pozzoli, S; Rotatori, F; Simonini, M; Zangrillo, A	1
BLOOMFIELD, RA; RAPOPORT, B	2
Bagrov, AY; Fedorova, OV; Shapiro, JI	1
Bartz, M; Bloch, W; Hauck, C; McDonough, AA; Mehlhorn, U; Müller-Ehmsen, J; Potter, T; Scheiner-Bobis, G; Schwinger, RH; Wahlers, T; Wittwer, T	1
Carpini, SD; Casamassima, N; Gatti, G; Hamlyn, JM; Manunta, P; Messaggio, E; Zagato, L	1
Funder, JW	1
Baba, A; Furutani, K; Kamimura, D; Komiyama, Y; Komuro, I; Mano, T; Matsuda, T; Miwa, T; Ohtani, T; Omori, Y; Sakata, Y; Takahashi, H; Takeda, Y; Tamaki, S; Tsukamoto, Y; Umemura, S; Yamamoto, K; Yoshika, M	1
Baran, PS; Renata, H; Zhou, Q	1
Hasenfuss, G; Houser, S; Maier, LS; Piacentino, V; Pieske, B; Weisser, J	1
Hageman, KS; Hansen, J; Helwig, B; McAllister, RM; Mitchell, KE; Musch, TI; Schreurs, KM; Zbreski, MG	1
FARAH, AE; GRUHZIT, CC	1
TORSTI, P	1
FEINSTEIN, MB	1
NAGASAKI, Y	1
BRAUNWALD, E; MASON, DT	1
BROADBENT, JL	1
FOWLER, NO; HOLMES, JC	1
SCHAUMANN, W	1
DATLOW, DW; DEVITA, VT; GOOCH, AS; MASSUMI, RA; NUTTER, D; RIOS, JC	1
Balke, CW; Blaustein, MP; Gottlieb, SS; Hamlyn, JM; Robinson, SW	1
Csermely, P; Pándics, T; Rosta, K; Somogyi, J; Szalay, J; Vér, A	1
Ferrandi, M; Manunta, P	1
Aronsen, JM; Birkeland, JA; Enger, UH; Louch, WE; Sejersted, OM; Sjaastad, I; Swift, F; Tovsrud, N	1
Cohn, LJ; Donoso, E; Friedberg, CK; Schloff, L; Stein, WG	1
Varma, DR; Wendlandt, S	1
Briggs, FN; Gertz, EW; Hess, ML; Lain, RF	1
Godfraind, T	1
Newman, WH; Privitera, PJ; Webb, JG	1
Hutton, I; Lawrie, TD; Martin, W; Murray, RG; Pearson, D; Tweddel, AC	1
Newman, WH; Webb, JG	1
Gilmore, JP; Peterson, TV; Zucker, IH	1
Britton, LW; Ferraris, VA; Kiser, LM; Sim, MF; Wallace, AM; Weishaar, RE	1
Huang, BS; Leenen, FH; Yu, H; Yuan, B	1
Baggioni, A; Crozatier, B; el Ouazzani, T; Ezzaher, A; Maixent, JM; Mougenot, R	1
Kaaja, RJ; Lewis, JG; Lewis, LK; Nicholls, MG; Pidgeon, GB; Richards, AM; Yandle, TG	1
Aksnes, G; Ellingsen, O; Holthe, MR; Ilebekk, A; Sejersted, OM; Svindland, A	1
Delehanty, JM; Fan, TH; Hang, CL; Himura, Y; Kelly, PF; Kim, CH; Liang, CS	1
Elam, H; Fan, TH; Frantz, RP; Imai, N; Liang, CS; Sakamoto, S	1
Allen, PD; Colucci, WS; Kjeldsen, K; Marsh, JD; Schmidt, TA	1
Bavendiek, U; Brixius, K; Erdmann, E; Frank, K; Gross, A; Müller-Ehmsen, J; Pietsch, M; Reuter, H; Schwinger, RH	1
Allen, PD; Alpert, NR; Hasenfuss, G; Just, H; Mulieri, LA	1
Brixius, K; Frank, K; Müller-Ehmsen, J; Schwinger, RH	1
Megges, R; Repke, KR; Weiland, J	1
Lloyd, S; Mattson, JP; Musch, TI; Pickar, JG	1
Brixius, K; Erdmann, E; Frank, K; McDonough, AA; Müller-Ehmsen, J; Schwinger, RH; Wang, J	1
Huang, BS; Leenen, FH; Zhang, W	1
Askew, GR; Croyle, ML; Grupp, G; Grupp, IL; James, PF; Lingrel, JB; Walsh, RA; Woo, AL	1
Casarotto, D; Ferrari, M; Magnolfi, G; Padrini, R; Panfili, M; Piovan, D	1
Maier, LS; Minami, K; Pieske, B; Schillinger, W; Schütt, U; Schwan, C	1
Huang, BS; Leenen, FH; Yuan, B	1
Allen, PD; Crambert, G; Lelievr, LG	1
Dilly, KW; Gómez, AM; Guatimosim, S; Lederer, WJ; Vassort, G	1
Böhm, M; Erdmann, E; Schwinger, R	1
Farley, RA; McDonough, AA; Velotta, JB; Wang, J	1
Detweiler, DK; Knight, DH	1
Awan, NA; Mason, DT	1
Coltart, DJ; Evans, TR; Shillingford, JP; Zacharoulis, AA; Ziady, GM	1
Lüderitz, B; Naumann d'Alnoncourt, C; Steinbeck, G	1
Bhattacharya, SS; Flear, CT; Greener, JS	1
Gunnar, RM; Rahimtoola, SH	1
Marcus, FI	1
Walther, JU	1
Alousi, AA; Santa Barbara, L	1
Dhalla, NS; Dixon, IM; Hata, T	1
Edwards, BS; Lloyd, MA; Sandberg, SM	1
Gottlieb, SS; Hamilton, BP; Hamlyn, JM; Krichten, CM; Rogowski, AC; Weinberg, M	1
Allen, PD; Kjeldsen, K; Marsh, JD; Schmidt, TA	1
Danielsen, W; Mende, U; Meyer, W; Neumann, J; Nose, M; Reich, T; Schmitz, W; Scholz, H; Steinfath, M; von der Leyen, H	1
Evenou, JP; Hof, A; Hof, RP; Novosel, D	1
McClain, JM; Wang, W; Zucker, IH	1
Blaustein, MP; Hamlyn, JM	1
Fan, TH; Liang, CS; Sullebarger, JT; Torres, F	1
Böhm, M; Erdmann, E; Schwinger, RH	1
Bethke, T; Klimkiewicz, A; Kohl, C; Mehl, H; Mende, U; Meyer, W; Neumann, J; Schmitz, W; Scholz, H; von der Leyen, H	1
Wang, W; Zucker, IH	1
Chen, JS; Wang, W; Zucker, IH	2
Forth, W	1
Brown, L; Erdmann, E; Näbauer, M	1
Braunwald, E	2
Bassett, AL; Cameron, JS; Gaide, MS; Kimura, S; Kozlovskis, PL; Lodge, NJ; Myerburg, RJ	1
Gunnar, RM; Loeb, HS; Rahimtoola, SH	1
Barrillon, A; Gerbaux, A; Lenègre, J; Maurice, P	1
Brown, AL; Gordon, MS	1
Meyer, J	1
Repke, KR	1
Mead, RJ; Peterson, MB; Welty, JD	1
Fujii, J; Yazaki, Y	1
Dhalla, NS; Sulakhe, PV	1
Isono, C; Sakai, K; Sugano, S	1
Cohen, SN; Doyle, EF; Rutkowski, MM	1
Balasubramanian, V; Dhalla, NS; McNamara, DB; Singh, JN	1
Alousi, AA; Beards, JA	1
Kritcher, EM; Luchi, RJ	1
Schwartz, A; Vargo, TA; Wood, JM	1
Kośmider, S; Smolarz, W	1
Braunwald, E; Vatner, SF	1
Savitskiĭ, NN	1
Fiorentini, C; Guazzi, M; Magrini, F; Polese, A	1
Gabe, I; Jewitt, D; Maurer, B; Mills, C; Shillingford, J; Thomas, M	1
Kopp, H	1
Capone, RJ; Lee, G; Longhurst, J; Zelis, R	1
Abelmann, WH; Ramírez, A	1
Maggi, GC; Piscitello, F	1
Gold, HK; Smith, TW	1
Elenbaas, RM; Kimble, MA	1
Abelmann, WH; Kumar, R; Yankopoulos, NA	1
Fano, A; Haft, JI; Shahabadi, AE	1
Kabela, E; Mendez, R; Pastelin, G	1
Forester, W; Lewis, RP; Weissler, AM; Wilke, TA	1
Forssell, G; Nordlander, R; Nyquist, O; Orinius, E	1
Chidsey, CA; Ito, Y; Suko, J	1
Zelis, R	1
Adamska-Dyniewska, H	2
Chung, EK	1
Clough, G; Majid, PA; Saxton, C; Taylor, SH	1
Braunwald, E; Higgins, CB; Vatner, SF	1
Glodek, P; Heimburg, P; Kirchhof, S; Kochsiek, K; Larbig, D; Neubaur, J; Stahlnecker, E	1
Jacobson, ED; Shanbour, LL	1
Goldschlager, N; Robin, E	1
Block, A; Schorscher, E; Sommer, S; Wild, AJ	1
Jacob, R; Kissling, G; Segarra-Domenech, J	1
Cohn, JN; Khatri, IM; Tristani, FE	1

Reviews

23 review(s) available for ouabain and Heart Failure

Article	Year
Repurposing Cardiac Glycosides: Drugs for Heart Failure Surmounting Viruses. Molecules (Basel, Switzerland), 2021, Sep-16, Volume: 26, Issue:18 Topics: Antiviral Agents; Cardiac Glycosides; COVID-19; Digitoxin; Digoxin; Drug Repositioning; Heart Failure; Humans; Neoplasms; Ouabain; Pandemics; SARS-CoV-2; Sodium-Potassium-Exchanging ATPase; Virus Internalization; Virus Replication	2021
Sodium pumps, ouabain and aldosterone in the brain: A neuromodulatory pathway underlying salt-sensitive hypertension and heart failure. Cell calcium, 2020, Volume: 86 Topics: Aldosterone; Animals; Brain; Heart Failure; Humans; Hypertension; Ouabain; Sodium Chloride, Dietary; Sodium-Potassium-Exchanging ATPase	2020
Does the hormone "endogenous ouabain" exist in the human circulation? BioFactors (Oxford, England), 2018, Volume: 44, Issue:3 Topics: Blood Pressure; Cardiotonic Agents; Dissent and Disputes; Female; Heart Failure; Humans; Hypertension; Ouabain; Pregnancy; Quackery; Renal Insufficiency; Wedge Argument	2018
Endogenous cardiotonic steroids: physiology, pharmacology, and novel therapeutic targets. Pharmacological reviews, 2009, Volume: 61, Issue:1 Topics: Animals; Blood Pressure; Bufanolides; Cardiac Glycosides; Cardiotonic Agents; Diabetes Mellitus; Enzyme Inhibitors; Female; Heart Failure; Humans; Hypertension; Ouabain; Pre-Eclampsia; Pregnancy; Signal Transduction; Sodium-Potassium-Exchanging ATPase	2009
Endogenous ouabain in renal Na(+) handling and related diseases. Biochimica et biophysica acta, 2010, Volume: 1802, Issue:12 Topics: Adrenal Glands; Angiotensin II; Animals; Cell Proliferation; Diuretics; Drosophila; Epinephrine; Heart Failure; Homeostasis; Humans; Hypertension; Kidney; Myocytes, Cardiac; Myocytes, Smooth Muscle; Ouabain; Renal Insufficiency; Sodium; Sodium-Calcium Exchanger; Sodium-Potassium-Exchanging ATPase; Vasoconstriction	2010
Aldosterone, hypertension and heart failure: insights from clinical trials. Hypertension research : official journal of the Japanese Society of Hypertension, 2010, Volume: 33, Issue:9 Topics: Aldosterone; Animals; Anticholesteremic Agents; Atorvastatin; Clinical Trials as Topic; Dihydrotestosterone; Drug Therapy, Combination; Enzyme Inhibitors; Female; Heart Failure; Heptanoic Acids; Humans; Hydrocortisone; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypertension; Male; Mice; Mineralocorticoid Receptor Antagonists; Ouabain; Pyrroles; Quinolines; Rats; Spironolactone	2010
Sex, digitalis, and the sodium pump. Molecular interventions, 2003, Volume: 3, Issue:2 Topics: Animals; Clinical Trials as Topic; Digitalis; Digitalis Glycosides; Digoxin; Female; Heart Failure; Hormone Replacement Therapy; Humans; Male; Ouabain; Sex Factors; Sodium-Potassium-Exchanging ATPase	2003
[New steroid hormone family: endogenous cardiac glycosides and their role in physiologic and pathologic conditions]. Orvosi hetilap, 2004, Feb-08, Volume: 145, Issue:6 Topics: Cardiac Glycosides; Gene Expression Regulation; Heart Failure; Hormones; Humans; Hypertension; Ouabain; Signal Transduction; Sodium-Potassium-Exchanging ATPase	2004
Different effects of marinobufagenin and endogenous ouabain. Journal of hypertension, 2004, Volume: 22, Issue:2 Topics: Animals; Bufanolides; Enzyme Inhibitors; Heart Failure; Humans; Myocardium; Ouabain; Sodium-Potassium-Exchanging ATPase	2004
The biphasic action of cardiac glycosides on the Na+, K+-pump and its relevance in the treatment of heart failure. European heart journal, 1982, Volume: 3 Suppl D Topics: Absorption; Animals; Binding Sites; Cardiac Glycosides; Guinea Pigs; Heart Failure; Humans; In Vitro Techniques; Isoenzymes; Myocardial Contraction; Myocardium; Ouabain; Potassium; Sodium; Sodium-Potassium-Exchanging ATPase; Stimulation, Chemical	1982
Beta-blocking agents and positive inotropic agents in the therapy of chronic heart failure. Journal of cardiovascular pharmacology, 1990, Volume: 16 Suppl 5 Topics: Adrenergic beta-Antagonists; Animals; Cardiotonic Agents; Digitalis Glycosides; Heart Failure; Humans; Ouabain; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Sodium-Potassium-Exchanging ATPase	1990
Congestive heart failure in dogs: therapeutic concepts. Journal of the American Veterinary Medical Association, 1977, Jul-01, Volume: 171, Issue:1 Topics: Aldosterone; Animals; Blood Volume; Cardiac Output; Diet, Sodium-Restricted; Digitalis Glycosides; Digoxin; Diuretics; Dog Diseases; Dogs; Edema; Extracellular Space; Heart Failure; Infusions, Parenteral; Kidney; Ouabain; Thirst	1977
Digitalis in acute myocardial infarction: help or hazard? Annals of internal medicine, 1975, Volume: 82, Issue:2 Topics: Acute Disease; Animals; Arrhythmias, Cardiac; Blood Pressure; Cardiac Output; Depression, Chemical; Digitalis Glycosides; Diuretics; Furosemide; Heart Failure; Heart Ventricles; Hemodynamics; Humans; Myocardial Infarction; Myocardium; Ouabain; Shock, Cardiogenic	1975
Digitalis pharmacokinetics and metabolism. The American journal of medicine, 1975, Volume: 58, Issue:4 Topics: Atrial Fibrillation; Creatinine; Delayed-Action Preparations; Digitalis Glycosides; Digitoxin; Digoxin; Electrocardiography; Feces; Half-Life; Heart Failure; Humans; Kidney; Kinetics; Ouabain; Time Factors	1975
Endogenous ouabain: implications for cardiovascular disease diagnosis and therapy. Maryland medical journal (Baltimore, Md. : 1985), 1992, Volume: 41, Issue:6 Topics: Blood Pressure; Blood Volume; Heart Failure; Humans; Hypertension; Ouabain; Water-Electrolyte Balance	1992
Effects of digitalis on the normal and the failing heart. Journal of the American College of Cardiology, 1985, Volume: 5, Issue:5 Suppl A Topics: Acute Disease; Animals; Atrial Fibrillation; Chronic Disease; Coronary Circulation; Coronary Disease; Digitalis Glycosides; Dogs; Heart; Heart Failure; Humans; Hypoxia; Myocardial Contraction; Myocardium; Ouabain; Oxygen Consumption	1985
The failing myocardium. I. Drug management. The Medical clinics of North America, 1973, Volume: 57, Issue:1 Topics: Adrenergic alpha-Antagonists; Adult; Aged; Atropine; Blood Pressure; Blood Volume; Cardiac Output; Digitalis Glycosides; Dopamine; Female; Glucagon; Heart Failure; Humans; Isoproterenol; Male; Middle Aged; Myocardial Infarction; Norepinephrine; Ouabain; Plasma Substitutes; Shock, Cardiogenic	1973
[Digitalis medication before, during and after operations]. Der Anaesthesist, 1970, Volume: 19, Issue:10 Topics: Adult; Age Factors; Cardiomegaly; Digitalis Glycosides; Electrocardiography; Female; Heart Failure; Humans; Middle Aged; Ouabain; Phenytoin; Postoperative Care; Pregnancy; Pregnancy Complications, Cardiovascular; Preoperative Care; Pulmonary Heart Disease	1970
Peripheral circulatory control mechanisms in congestive heart failure. The American journal of cardiology, 1973, Sep-20, Volume: 32, Issue:4 Topics: Arteries; Blood Circulation; Blood Pressure; Edema; Forearm; Heart Failure; Humans; Hyperemia; Muscles; Ouabain; Oxygen Consumption; Physical Exertion; Pressoreceptors; Pressure; Receptors, Adrenergic; Regional Blood Flow; Skin; Sodium; Sympathetic Nervous System; Tyramine; Vascular Resistance	1973
Cardiac decompensation. The New England journal of medicine, 1974, Feb-28, Volume: 290, Issue:9 Topics: Acute Disease; Aminophylline; Assisted Circulation; Cardiac Glycosides; Digoxin; Diuretics; Electric Countershock; Heart; Heart Diseases; Heart Failure; Humans; Morphine; Ouabain; Oxygen Inhalation Therapy; Phentolamine; Pulmonary Edema; Tachycardia; Vasodilator Agents	1974
Congestive heart failure. Journal of the American Pharmaceutical Association, 1974, Volume: 14, Issue:7 Topics: Age Factors; Creatinine; Diet; Digitalis; Digitalis Glycosides; Digitoxin; Digoxin; Diuretics; Heart Failure; Humans; Hypercalcemia; Hypokalemia; Kidney; Kinetics; Liver; Magnesium; Ouabain; Plants, Medicinal; Plants, Toxic; Rest; Thyroid Gland; Time Factors	1974
The current status of digitalis therapy. Modern treatment, 1971, Volume: 8, Issue:3 Topics: Age Factors; Arrhythmias, Cardiac; Calcium; Child; Coronary Care Units; Digitalis Glycosides; Digoxin; Electric Countershock; Electrocardiography; Endocrine System Diseases; Heart Diseases; Heart Failure; Heart Rate; Heart Valve Diseases; Humans; Kidney Failure, Chronic; Liver Diseases; Lung Diseases; Magnesium; Obesity; Ouabain; Poisoning; Potassium; Psychophysiologic Disorders; Pulmonary Heart Disease; Thyroid Diseases; Time Factors	1971
Mechanics and energetics of the normal and failing heart. Transactions of the Association of American Physicians, 1971, Volume: 84 Topics: Animals; Biomechanical Phenomena; Blood Pressure; Cardiac Output; Cardiac Volume; Energy Metabolism; Heart; Heart Conduction System; Heart Failure; Humans; Models, Biological; Muscle Contraction; Myocardium; Norepinephrine; Ouabain; Oxygen Consumption; Papillary Muscles; Receptors, Adrenergic; Sympathetic Nervous System	1971

Trials

4 trial(s) available for ouabain and Heart Failure

Article	Year
Ouabain is not detectable in human plasma. Hypertension (Dallas, Tex. : 1979), 1994, Volume: 24, Issue:5 Topics: Animals; Antibodies; Antibody Specificity; Chromatography, High Pressure Liquid; Cross Reactions; Digoxin; Enzyme-Linked Immunosorbent Assay; Female; Fetal Blood; Heart Failure; Humans; Kidney Failure, Chronic; Ouabain; Pre-Eclampsia; Pregnancy; Rabbits; Sensitivity and Specificity; Steroids; Strophanthidin; Vasopressins	1994
[Treatment of latent heart insufficiency by Eoden-retard]. Zeitschrift fur Allgemeinmedizin, 1972, Dec-20, Volume: 48, Issue:35 Topics: Aged; Amino Alcohols; Clinical Trials as Topic; Drug Combinations; Evaluation Studies as Topic; Female; Heart Failure; Hemodynamics; Humans; Male; Middle Aged; Ouabain	1972
Effectiveness of orally administered G-strophantin on haemodynamics in cardiac patients. Arzneimittel-Forschung, 1973, Volume: 23, Issue:11 Topics: Administration, Oral; Aged; Clinical Trials as Topic; Heart; Heart Failure; Heart Rate; Hemodynamics; Humans; Male; Ouabain; Time Factors	1973
[Effect of combined treatment with hydantoinal and cardiac glycosides on the dynamics of left ventricular contraction]. Polskie Archiwum Medycyny Wewnetrznej, 1969, Volume: 43, Issue:1 Topics: Adult; Aged; Cardiac Glycosides; Clinical Trials as Topic; Drug Synergism; Heart Failure; Heart Rate; Heart Ventricles; Humans; Hydantoins; Middle Aged; Ouabain	1969

Other Studies

108 other study(ies) available for ouabain and Heart Failure

Article	Year
Comparative Therapeutic Potential of Cardioactive Glycosides in Doxorubicin Model of Heart Failure. Cardiovascular toxicology, 2022, Volume: 22, Issue:1 Topics: Animals; Cardenolides; Cardiac Glycosides; Cardiotonic Agents; Cardiotoxicity; Digoxin; Disease Models, Animal; Doxorubicin; Heart Failure; Ouabain; Rats, Wistar; Recovery of Function; Stroke Volume; Ventricular Function, Left; Ventricular Remodeling	2022
Digoxin as an emerging therapy in noncardiac diseases. Trends in pharmacological sciences, 2023, Volume: 44, Issue:4 Topics: Cardiac Glycosides; Digoxin; Heart Failure; Humans; Ouabain; Sodium-Potassium-Exchanging ATPase	2023
A genome-wide positioning systems network algorithm for in silico drug repurposing. Nature communications, 2019, 08-02, Volume: 10, Issue:1 Topics: Adenocarcinoma of Lung; Algorithms; Arrhythmias, Cardiac; Computer Simulation; Datasets as Topic; Drug Repositioning; Feasibility Studies; Gene Regulatory Networks; Heart Failure; Holistic Health; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Lung Neoplasms; Metabolic Networks and Pathways; Molecular Targeted Therapy; Ouabain; Protein Interaction Maps; Systems Biology; Transcription Factors; Transcriptome	2019
No endogenous ouabain is detectable in human plasma by ultra-sensitive UPLC-MS/MS. Clinica chimica acta; international journal of clinical chemistry, 2014, Apr-20, Volume: 431 Topics: Calibration; Cardiotonic Agents; Chromatography, High Pressure Liquid; Heart Failure; Humans; Limit of Detection; Molecular Weight; Ouabain; Quality Control; Reference Standards; Reproducibility of Results; Tandem Mass Spectrometry	2014
Ouabain induces nitric oxide release by a PI3K/Akt-dependent pathway in isolated aortic rings from rats with heart failure. Journal of cardiovascular pharmacology, 2015, Volume: 65, Issue:1 Topics: Animals; Aorta, Thoracic; Heart Failure; Male; Myocardial Infarction; NG-Nitroarginine Methyl Ester; Nitric Oxide; Ouabain; Phenylephrine; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Rats; Rats, Wistar	2015
Endogenous Ouabain: An Old Cardiotonic Steroid as a New Biomarker of Heart Failure and a Predictor of Mortality after Cardiac Surgery. BioMed research international, 2015, Volume: 2015 Topics: Biomarkers; Cardiac Surgical Procedures; Cardiotonic Agents; Echocardiography; Female; Heart Failure; Humans; Male; Middle Aged; Ouabain; Postoperative Period; Prognosis; Prospective Studies; Risk Assessment; Steroids	2015
The effects of the cardiac glycosides upon the dynamics of the circulation in congestive heart failure; ouabain. The Journal of clinical investigation, 1948, Volume: 27, Issue:5 Topics: Cardiac Glycosides; Heart; Heart Failure; Humans; Ouabain	1948
Isoform specificity of cardiac glycosides binding to human Na+,K+-ATPase alpha1beta1, alpha2beta1 and alpha3beta1. European journal of pharmacology, 2009, Nov-10, Volume: 622, Issue:1-3 Topics: Animals; Cardiac Glycosides; Cell Membrane; H(+)-K(+)-Exchanging ATPase; Heart Failure; Humans; Immunohistochemistry; Intracellular Space; Isoenzymes; Myocytes, Cardiac; Ouabain; Protein Binding; Saccharomyces cerevisiae; Sodium-Potassium-Exchanging ATPase; Substrate Specificity	2009
The effect of ouabain on the dynamics of the circulation in patients with congestive heart failure. The Journal of clinical investigation, 1947, Volume: 26, Issue:6 Topics: Heart; Heart Failure; Humans; Ouabain; Treatment Failure	1947
Ca2+ entry mode of Na+/Ca2+ exchanger as a new therapeutic target for heart failure with preserved ejection fraction. European heart journal, 2012, Volume: 33, Issue:11 Topics: Animals; Calcium; Cardenolides; Fibrosis; Heart Failure; Heart Ventricles; Myofibroblasts; Ouabain; Rats; Rats, Inbred Dahl; Rats, Sprague-Dawley; Saponins; Sodium-Calcium Exchanger; Stroke Volume; Tibia	2012
Strategic redox relay enables a scalable synthesis of ouabagenin, a bioactive cardenolide. Science (New York, N.Y.), 2013, Jan-04, Volume: 339, Issue:6115 Topics: Cardenolides; Heart Failure; Humans; Ouabain; Oxidation-Reduction	2013
Rate dependence of [Na+]i and contractility in nonfailing and failing human myocardium. Circulation, 2002, Jul-23, Volume: 106, Issue:4 Topics: Benzofurans; Calcium; Cells, Cultured; Culture Techniques; Electric Conductivity; Electric Stimulation; Fluorescent Dyes; Heart Failure; Homeostasis; Humans; Ion Transport; Kinetics; Middle Aged; Myocardial Contraction; Myocardium; Ouabain; Phthalic Acids; Sodium	2002
Training-induced changes in skeletal muscle Na+-K+ pump number and isoform expression in rats with chronic heart failure. Journal of applied physiology (Bethesda, Md. : 1985), 2003, Volume: 94, Issue:6 Topics: Animals; Binding Sites; Chronic Disease; Female; Heart Failure; Isoenzymes; Muscle, Skeletal; Ouabain; Oxygen Consumption; Physical Conditioning, Animal; Physical Endurance; Rats; Rats, Wistar; Sodium-Potassium-Exchanging ATPase	2003
A comparison of the positive inotropic effects of ouabain and epinephrine in heart failure induced in the dog heart-lung preparation by sodium pentobarbital, dinitrophenol, sodium cyanide and sodium azide. The Journal of pharmacology and experimental therapeutics, 1955, Volume: 114, Issue:3 Topics: Animals; Dinitrophenols; Dogs; Epinephrine; Heart; Heart Failure; Ouabain; Pentobarbital; Sodium; Sodium Azide; Sodium Cyanide; Strophanthins	1955
The acetylcholine content and cholinesterase activities in the rabbit heart in experimental heart failure and the effect of g-strophanthin treatment upon them. Annales medicinae experimentalis et biologiae Fenniae, 1959, Volume: 37(Suppl 4) Topics: Acetylcholine; Animals; Cholinesterases; Heart; Heart Failure; Myocardium; Ouabain; Rabbits; Strophanthins; Synaptic Transmission	1959
Effects of experimental congestive heart failure, ouabain, and asphyxia on the high-energy phosphate and creatine content of the guinea pig heart. Circulation research, 1962, Volume: 10 Topics: Asphyxia; Creatine; Creatinine; Guinea Pigs; Heart; Heart Failure; Myocardium; Ouabain; Phosphates; Strophanthins	1962
Studies on isometric contractility of glycerinated fibers from normal and failing cardiac muscles, and their response to the administration of ouabain. Japanese circulation journal, 1962, Volume: 26 Topics: Heart; Heart Failure; Humans; Isometric Contraction; Myocardium; Ouabain; Strophanthins	1962
STUDIES ON DIGITALIS. X. EFFECTS OF OUABAIN ON FOREARM VASCULAR RESISTANCE AND VENOUS TONE IN NORMAL SUBJECTS AND IN PATIENTS IN HEART FAILURE. The Journal of clinical investigation, 1964, Volume: 43 Topics: Blood Flow Velocity; Digitalis; Forearm; Guanethidine; Heart Failure; Humans; Ouabain; Pharmacology; Plethysmography; Strophanthins; Vascular Resistance; Veins	1964
EFFECT OF SUPERFUSED OUABAIN ON THE CONTRACTILITY OF THE HEART OF THE FROG. Nature, 1964, May-16, Volume: 202 Topics: Animals; Anura; Heart; Heart Failure; Muscle Proteins; Ouabain; Perfusion; Pharmacology; Research	1964
DEXTRAN-EXCHANGE ANEMIA AND REDUCTION IN BLOOD VISCOSITY IN THE HEART-LUNG PREPARATION; WITH AN OBSERVATION UPON THE ACTION OF OUABAIN IN ANEMIC HEART FAILURE. American heart journal, 1964, Volume: 68 Topics: Anemia; Animals; Blood Pressure; Blood Viscosity; Citric Acid Cycle; Dextrans; Dogs; Heart; Heart Failure; Hematocrit; Hemodynamics; Humans; Lung; Ouabain; Pharmacology; Research	1964
[CIRCULATORY EFFECTS OF G-STROPHANTHIN ON NORMAL GUINEA PIGS AND THOSE WITH CARDIAC INSUFFICIENCY]. Naunyn-Schmiedebergs Archiv fur experimentelle Pathologie und Pharmakologie, 1964, May-29, Volume: 247 Topics: Arrhythmias, Cardiac; Bemegride; Blood Pressure Determination; Guinea Pigs; Heart Arrest; Heart Failure; Heart Function Tests; Ouabain; Pharmacology; Research; Strophanthins; Vagotomy	1964
PRIMARY MYOCARDIAL DISEASE: REPORT OF FIFTY CASES AND REVIEW OF THE SUBJECT. Circulation, 1965, Volume: 31 Topics: Alcoholism; Arrhythmias, Cardiac; Cardiac Catheterization; Cardiomegaly; Cardiomyopathies; Deficiency Diseases; Digitalis Glycosides; Drug Therapy; Electrocardiography; Embolism; Geriatrics; Heart Failure; Heart Function Tests; Hemodynamics; Humans; Kinetocardiography; Myocardium; Ouabain; Pathology; Phonocardiography; Radiography, Thoracic; Toxicology	1965
Altered Na+/Ca2+-exchanger activity due to downregulation of Na+/K+-ATPase alpha2-isoform in heart failure. Cardiovascular research, 2008, Apr-01, Volume: 78, Issue:1 Topics: Animals; Calcium Signaling; Cytoskeleton; Disease Models, Animal; Down-Regulation; Enzyme Inhibitors; Heart Failure; Immunohistochemistry; Male; Membrane Potentials; Microscopy, Confocal; Microscopy, Electron; Muscle Contraction; Myocardial Infarction; Myocytes, Cardiac; Ouabain; Patch-Clamp Techniques; Rats; Rats, Wistar; Sodium; Sodium-Calcium Exchanger; Sodium-Potassium-Exchanging ATPase	2008
The effect of digitalis in compensated and decompensated patients with internal cardiac pacemakers. American heart journal, 1967, Volume: 73, Issue:5 Topics: Adams-Stokes Syndrome; Aged; Arteriosclerosis; Blood Pressure; Cardiac Output; Digitalis Glycosides; Female; Heart Failure; Heart Function Tests; Humans; Male; Ouabain; Oxygen Consumption; Pacemaker, Artificial; Spirometry	1967
Influence of reserpine, heart failure, and immunosympathectomy on the cardiac effects of ouabain. Canadian journal of physiology and pharmacology, 1967, Volume: 45, Issue:4 Topics: Adrenalectomy; Animals; Blood Pressure; Cats; Female; Heart; Heart Failure; Male; Norepinephrine; Ouabain; Papillary Muscles; Pulmonary Valve Stenosis; Reserpine; Sympathectomy; Ventricular Fibrillation	1967
Activity of the vesicular calcium pump in the spontaneously failing heart-lung preparation. Circulation research, 1967, Volume: 20, Issue:5 Topics: Adenosine Triphosphate; Animals; Calcium; Cardiac Output; Dogs; Extracorporeal Circulation; Heart Failure; In Vitro Techniques; Ouabain; Sarcolemma	1967
Persistence of myocardial failure following removal of chronic volume overload. The American journal of physiology, 1982, Volume: 243, Issue:6 Topics: Animals; Blood Pressure; Body Weight; Dogs; Heart; Heart Failure; Heart Rate; Heart Ventricles; Isoproterenol; Myocardial Contraction; Norepinephrine; Ouabain; Renin	1982
Evaluation of digitalis in cardiac failure. British medical journal (Clinical research ed.), 1982, May-22, Volume: 284, Issue:6328 Topics: Adult; Aged; Digoxin; Female; Heart Failure; Hemodynamics; Humans; Male; Middle Aged; Ouabain; Physical Exertion; Stroke Volume	1982
A differential inotropic responsiveness to isoprenaline and ouabain in dogs with heart failure. Cardiovascular research, 1980, Volume: 14, Issue:9 Topics: Animals; Dogs; Dose-Response Relationship, Drug; Heart Failure; Isoproterenol; Myocardial Contraction; Norepinephrine; Ouabain	1980
Ouabain increases left atrial stretch receptor discharge in the dog. The Journal of pharmacology and experimental therapeutics, 1980, Volume: 212, Issue:2 Topics: Animals; Blood Pressure; Blood Volume; Cardiac Glycosides; Dogs; Heart; Heart Atria; Heart Failure; Heart Rate; Hemodynamics; Kidney; Mechanoreceptors; Ouabain; Sympathetic Nervous System; Time Factors	1980
Assessment of flosequinan's direct effect on human arterial, venous, and cardiac muscle: comparison with other classes of agents used to treat heart failure. Journal of cardiovascular pharmacology, 1994, Volume: 23, Issue:5 Topics: Captopril; Diltiazem; Heart Failure; Humans; In Vitro Techniques; Milrinone; Muscle Contraction; Muscle, Smooth, Vascular; Myocardial Contraction; Ouabain; Pyridones; Quinolines; Quinolones; Vasodilator Agents	1994
Brain 'ouabain' mediates sympathetic hyperactivity in congestive heart failure. Circulation research, 1995, Volume: 77, Issue:5 Topics: Animals; Brain; Brain Chemistry; Cardiomyopathies; Catecholamines; Cricetinae; Digoxin; Guanabenz; Heart Failure; Hemodynamics; Immunoglobulin Fab Fragments; In Vitro Techniques; Male; Myocardial Infarction; Myocardium; Ouabain; Rats; Rats, Wistar; Stress, Physiological; Sympathetic Nervous System	1995
Inotropic effects of ouabain and Na, K-ATPase activity in failing rabbit hearts. Comptes rendus de l'Academie des sciences. Serie III, Sciences de la vie, 1995, Volume: 318, Issue:2 Topics: Animals; Cardiotonic Agents; Heart Failure; Ouabain; Rabbits; Sodium-Potassium-Exchanging ATPase; Ventricular Function, Left	1995
Na,K-pump concentration in hypertrophied human hearts. European heart journal, 1994, Volume: 15, Issue:9 Topics: Aged; Body Constitution; Cardiomegaly; Heart Failure; Heart Ventricles; Humans; Myocardium; Ouabain; Sodium-Potassium-Exchanging ATPase	1994
Isoform-specific regulation of myocardial Na,K-ATPase alpha-subunit in congestive heart failure. Role of norepinephrine. Circulation, 1994, Volume: 89, Issue:1 Topics: Animals; Binding Sites; Blotting, Western; Cardiac Pacing, Artificial; Dogs; Down-Regulation; Heart Failure; Isoenzymes; Myocardium; Norepinephrine; Ouabain; Sodium-Potassium-Exchanging ATPase	1994
Reductions of myocardial Na-K-ATPase activity and ouabain binding sites in heart failure: prevention by nadolol. The American journal of physiology, 1993, Volume: 265, Issue:6 Pt 2 Topics: Animals; Binding Sites; Dogs; Heart Failure; Hemodynamics; Isometric Contraction; Male; Myocardial Contraction; Myocardium; Nadolol; Ouabain; Sodium-Potassium-Exchanging ATPase; Strophanthidin; Ventricular Function, Right	1993
No adaptation to digitalization as evaluated by digitalis receptor (Na,K-ATPase) quantification in explanted hearts from donors without heart disease and from digitalized recipients with end-stage heart failure. The American journal of cardiology, 1993, Jan-01, Volume: 71, Issue:1 Topics: Adult; Digoxin; Female; Heart Failure; Heart Transplantation; Heart Ventricles; Humans; Male; Middle Aged; Myocardium; Ouabain; Potassium; Receptors, Drug; Sodium-Potassium-Exchanging ATPase; Stroke Volume; Time Factors; Tritium; Up-Regulation	1993
Altered inotropism in the failing human myocardium. Basic research in cardiology, 1996, Volume: 91 Suppl 2 Topics: Adrenergic beta-Agonists; Azetidines; Calcium; Calcium-Binding Proteins; Calcium-Transporting ATPases; Cardiotonic Agents; Dose-Response Relationship, Drug; Electric Stimulation; Enzyme Inhibitors; Heart Failure; Humans; In Vitro Techniques; Indoles; Isoproterenol; Myocardial Contraction; Myocardium; Ouabain; Sarcoplasmic Reticulum; Sodium	1996
Influence of isoproterenol and ouabain on excitation-contraction coupling, cross-bridge function, and energetics in failing human myocardium. Circulation, 1996, Dec-15, Volume: 94, Issue:12 Topics: Cardiomyopathies; Energy Metabolism; Heart; Heart Failure; Heart Transplantation; Humans; In Vitro Techniques; Isoproterenol; Middle Aged; Myocardial Contraction; Myocardium; Ouabain; Thermodynamics	1996
Increase in force of contraction by activation of the Na+/Ca(2+)-exchanger in human myocardium. British journal of clinical pharmacology, 1997, Volume: 43, Issue:4 Topics: Adrenergic beta-Agonists; Antiporters; Azetidines; Calcium; Cardiotonic Agents; Dose-Response Relationship, Drug; Electric Stimulation; Enzyme Inhibitors; Heart Failure; Heart Transplantation; Humans; Isoproterenol; Muscle Contraction; Muscle Fibers, Skeletal; Muscle, Smooth, Vascular; Myocardial Contraction; Ouabain; Papillary Muscles; Sodium; Sodium-Calcium Exchanger; Sodium-Potassium-Exchanging ATPase	1997
Differentiation between various types of inotropes through discovery of differences in their ability to detect isoforms of Na+/K(+)-ATPase. Journal of enzyme inhibition, 1997, Volume: 12, Issue:1 Topics: Abietanes; Alkaloids; Animals; Bufanolides; Cardiotonic Agents; Enzyme Inhibitors; Heart Failure; Isoenzymes; Ouabain; Progesterone; Rats; Sciatic Nerve; Sodium-Potassium-Exchanging ATPase	1997
Decreased [3H]ouabain binding sites in skeletal muscle of rats with chronic heart failure. Journal of applied physiology (Bethesda, Md. : 1985), 1997, Volume: 83, Issue:1 Topics: Animals; Binding Sites; Chronic Disease; Female; Heart Failure; Locomotion; Muscle Contraction; Muscle, Skeletal; Myocardial Infarction; Ouabain; Rats; Rats, Wistar; Sodium Channels; Sodium-Potassium-Exchanging ATPase; Ventricular Dysfunction, Left	1997
Reduced sodium pump alpha1, alpha3, and beta1-isoform protein levels and Na+,K+-ATPase activity but unchanged Na+-Ca2+ exchanger protein levels in human heart failure. Circulation, 1999, Apr-27, Volume: 99, Issue:16 Topics: Adolescent; Adult; Binding Sites; Calsequestrin; Cardiomyopathy, Dilated; Female; Heart Failure; Heart Transplantation; Heart Ventricles; Humans; Isoenzymes; Male; Middle Aged; Myocardium; Ouabain; Papillary Muscles; Reference Values; Sodium-Calcium Exchanger; Sodium-Potassium-Exchanging ATPase	1999
Brain renin-angiotensin system and sympathetic hyperactivity in rats after myocardial infarction. The American journal of physiology, 1999, Volume: 276, Issue:5 Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Baroreflex; Blood Pressure; Brain; Cardiotonic Agents; Enzyme Inhibitors; Guanabenz; Heart Failure; Heart Rate; Injections, Intraventricular; Losartan; Male; Myocardial Infarction; Nitroprusside; Ouabain; Phenylephrine; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Renin-Angiotensin System; Stress, Physiological; Sympathetic Nervous System	1999
Identification of a specific role for the Na,K-ATPase alpha 2 isoform as a regulator of calcium in the heart. Molecular cell, 1999, Volume: 3, Issue:5 Topics: Animals; Calcium; Calcium Signaling; Enzyme Inhibitors; Glycosides; Heart Failure; Heart Ventricles; Heterozygote; Isoenzymes; Mice; Mice, Transgenic; Muscle Fibers, Skeletal; Myocardial Contraction; Myocardium; Ouabain; RNA, Messenger; Sodium-Potassium-Exchanging ATPase; Stem Cells	1999
Myocardial region (right or left ventricle) and aetiology of heart failure can influence the inotropic effect of ouabain in failing human myocardium. British journal of clinical pharmacology, 1999, Volume: 48, Issue:5 Topics: Aging; Cardiomyopathy, Dilated; Cardiotonic Agents; Female; Heart Failure; Hemodynamics; Humans; In Vitro Techniques; Male; Middle Aged; Myocardial Contraction; Myocardial Ischemia; Myocardium; Ouabain; Ventricular Dysfunction, Left; Ventricular Dysfunction, Right	1999
Gingerol, isoproterenol and ouabain normalize impaired post-rest behavior but not force-frequency relation in failing human myocardium. Cardiovascular research, 2000, Volume: 45, Issue:4 Topics: Adult; Analysis of Variance; Calcium; Calcium-Transporting ATPases; Cardiotonic Agents; Catechols; Cyclic AMP; Enzyme Inhibitors; Fatty Alcohols; Heart Failure; Humans; Isoproterenol; Middle Aged; Myocardial Contraction; Myocardium; Ouabain; Sarcoplasmic Reticulum; Sodium-Potassium-Exchanging ATPase; Stimulation, Chemical; Thapsigargin	2000
Chronic blockade of brain "ouabain" prevents sympathetic hyper-reactivity and impairment of acute baroreflex resetting in rats with congestive heart failure. Canadian journal of physiology and pharmacology, 2000, Volume: 78, Issue:1 Topics: Animals; Guanabenz; Heart Failure; Hemodynamics; Immunoglobulin Fab Fragments; Injections, Intraventricular; Male; Myocardial Infarction; Nitroprusside; Ouabain; Pressoreceptors; Rats; Rats, Wistar; Reflex; Sympathetic Nervous System	2000
Expression of functional Na,K-ATPase isozymes in normal human cardiac biopsies. Cellular and molecular biology (Noisy-le-Grand, France), 2001, Volume: 47, Issue:2 Topics: Animals; Biopsy; Cell Fractionation; Dose-Response Relationship, Drug; Enzyme Inhibitors; Heart Failure; Humans; Isoenzymes; Microsomes; Myocardium; Ouabain; Radioligand Assay; Sodium-Potassium-Exchanging ATPase	2001
Heart failure after myocardial infarction: altered excitation-contraction coupling. Circulation, 2001, Aug-07, Volume: 104, Issue:6 Topics: Animals; Calcium; Calcium Channels; Calcium Signaling; Cardiotonic Agents; Cell Size; Heart Failure; Hypertrophy; Male; Membrane Potentials; Myocardial Contraction; Myocardial Infarction; Myocardium; Ouabain; Rats; Rats, Wistar; Sarcoplasmic Reticulum; Survival Rate; Tetrodotoxin	2001
All human Na(+)-K(+)-ATPase alpha-subunit isoforms have a similar affinity for cardiac glycosides. American journal of physiology. Cell physiology, 2001, Volume: 281, Issue:4 Topics: Cardiotonic Agents; Heart Failure; Humans; In Vitro Techniques; Isoenzymes; Myocardium; Ouabain; Sodium-Potassium-Exchanging ATPase; Tritium	2001
Recent advances in digitalis research. The American journal of cardiology, 1979, Volume: 43, Issue:5 Topics: Arrhythmias, Cardiac; Chronic Disease; Coronary Circulation; Coronary Disease; Digitalis Glycosides; Digoxin; Heart Failure; Hemodynamics; Humans; Myocardial Contraction; Myocardium; Ouabain; Oxygen Consumption	1979
Measurement of stroke volume from pulmonary artery pressure record in man. British heart journal, 1975, Volume: 37, Issue:1 Topics: Blood Pressure; Cardiac Catheterization; Cardiac Output; Cardiomyopathy, Hypertrophic; Catecholamines; Coronary Disease; Dye Dilution Technique; Electrocardiography; Female; Heart Failure; Heart Function Tests; Heart Rate; Humans; Isoproterenol; Male; Mitral Valve Insufficiency; Myocardial Infarction; Nitroglycerin; Ouabain; Phenethylamines; Phenols; Practolol; Pulmonary Artery; Pulse	1975
Effects of antikaliuretic agents on cardiac electrophysiology--measurements in papillary heart muscle and in purkinje fibers. Klinische Wochenschrift, 1977, May-01, Volume: 55, Issue:9 Topics: Action Potentials; Amiloride; Animals; Canrenoic Acid; Cardiac Glycosides; Diuretics; Dogs; Dose-Response Relationship, Drug; Drug Interactions; Guinea Pigs; Heart Conduction System; Heart Failure; Membrane Potentials; Ouabain; Papillary Muscles; Purkinje Fibers; Refractory Period, Electrophysiological; Triamterene	1977
Effects of ouabain on sodium uptake by frog heart and skeletal muscle. Recent advances in studies on cardiac structure and metabolism, 1975, Volume: 5 Topics: Animals; Anura; Biological Transport; Dose-Response Relationship, Drug; Heart; Heart Failure; In Vitro Techniques; Muscles; Myocardium; Ouabain; Permeability; Potassium; Rana temporaria; Sodium	1975
Letter: Ouabain in heart failure. British medical journal, 1975, Mar-01, Volume: 1, Issue:5956 Topics: Heart Failure; Humans; Ouabain	1975
Effects of ouabain and norepinephrine on the mechanical performance of the normal and failing heart of the myopathic hamster. Recent advances in studies on cardiac structure and metabolism, 1976, Volume: 9 Topics: Animals; Blood Pressure; Cricetinae; Disease Models, Animal; Heart; Heart Failure; Male; Myocardium; Norepinephrine; Ouabain; Oxygen Consumption	1976
Sarcolemmal Na(+)-K(+)-ATPase activity in congestive heart failure due to myocardial infarction. The American journal of physiology, 1992, Volume: 262, Issue:3 Pt 1 Topics: Alamethicin; Animals; Heart Failure; Hydrogen-Ion Concentration; Kinetics; Male; Myocardial Infarction; Ouabain; Rats; Rats, Inbred Strains; Sarcolemma; Sodium-Potassium-Exchanging ATPase	1992
Role of renal Na+,K(+)-ATPase in the regulation of sodium excretion under normal conditions and in acute congestive heart failure. Circulation, 1992, Volume: 85, Issue:5 Topics: Acute Disease; Animals; Dogs; Endocrine Glands; Female; Heart Failure; Hemodynamics; Kidney; Male; Natriuresis; Ouabain; Reference Values; Sodium-Potassium-Exchanging ATPase	1992
Elevated concentrations of endogenous ouabain in patients with congestive heart failure. Circulation, 1992, Volume: 86, Issue:2 Topics: Digoxin; Female; Glomerular Filtration Rate; Heart Failure; Hemodynamics; Homeostasis; Humans; Immunoassay; Male; Middle Aged; Ouabain; Sodium-Potassium-Exchanging ATPase	1992
Na,K-ATPase expression in normal and failing human left ventricle. Basic research in cardiology, 1992, Volume: 87 Suppl 1 Topics: Binding Sites; Digoxin; Gene Expression Regulation; Heart Failure; Heart Ventricles; Humans; Isoenzymes; Myocardium; Ouabain; RNA, Messenger; Sodium-Potassium-Exchanging ATPase	1992
Reduced alpha 1- and beta 2-adrenoceptor-mediated positive inotropic effects in human end-stage heart failure. British journal of pharmacology, 1992, Volume: 105, Issue:2 Topics: 3',5'-Cyclic-AMP Phosphodiesterases; 3',5'-Cyclic-GMP Phosphodiesterases; Adrenergic alpha-Agonists; Adrenergic beta-Agonists; Adult; Calcium; Female; Heart Failure; Humans; In Vitro Techniques; Male; Middle Aged; Muscle Proteins; Myocardial Contraction; Ouabain; Phosphoric Diester Hydrolases; Radioligand Assay; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Stimulation, Chemical	1992
Autonomic nervous system dysfunction alters drug effects: implications for testing drugs for the treatment of heart failure. Journal of cardiovascular pharmacology, 1992, Volume: 20, Issue:1 Topics: Animals; Autonomic Nervous System; Cardiovascular Agents; Disease Models, Animal; Enalapril; Heart Failure; Heart Rate; Milrinone; Myocardial Contraction; Nitroprusside; Ouabain; Propranolol; Pyridones; Rabbits; Vagotomy; Vasodilator Agents	1992
Aldosterone reduces baroreceptor discharge in the dog. Hypertension (Dallas, Tex. : 1979), 1992, Volume: 19, Issue:3 Topics: Aldosterone; Animals; Blood Pressure; Disease Models, Animal; Dogs; Endothelium, Vascular; Female; Heart Failure; Male; Ouabain; Pressoreceptors; Receptors, Glucocorticoid; Receptors, Mineralocorticoid; Spironolactone	1992
Both cell surface and internalized beta-adrenoceptors are reduced in the failing myocardium. European journal of pharmacology, 1991, Nov-26, Volume: 205, Issue:2 Topics: Animals; Binding Sites; Cell Membrane; Dogs; Heart Failure; Iodocyanopindolol; Ouabain; Pindolol; Receptors, Adrenergic, beta; Sodium-Potassium-Exchanging ATPase	1991
Effectiveness of cardiac glycosides in human myocardium with and without "downregulated" beta-adrenoceptors. Journal of cardiovascular pharmacology, 1990, Volume: 15, Issue:5 Topics: Adult; Cardiac Glycosides; Cardiomyopathies; Down-Regulation; Female; Heart; Heart Failure; Humans; In Vitro Techniques; Isoproterenol; Male; Middle Aged; Myocardial Contraction; Ouabain; Papillary Muscles; Receptors, Adrenergic, beta; Sodium-Potassium-Exchanging ATPase	1990
Effects of isomazole on force of contraction and phosphodiesterase isoenzymes I-IV in nonfailing and failing human hearts. Journal of cardiovascular pharmacology, 1991, Volume: 18, Issue:3 Topics: Adult; Calcium; Chromatography, DEAE-Cellulose; Electric Stimulation; Female; Heart; Heart Failure; Humans; Imidazoles; In Vitro Techniques; Isoenzymes; Isoproterenol; Male; Middle Aged; Milrinone; Myocardial Contraction; Myocardium; Ouabain; Phosphodiesterase Inhibitors; Phosphoric Diester Hydrolases; Pyridazines; Pyridones	1991
Modulation of baroreflex and baroreceptor function in experimental heart failure. Basic research in cardiology, 1991, Volume: 86 Suppl 3 Topics: Animals; Blood Pressure; Disease Models, Animal; Dogs; Electrophysiology; Heart Failure; Heart Rate; Nitroglycerin; Ouabain; Phenylephrine; Pressoreceptors; Reflex, Abnormal; Vagotomy	1991
Postexcitatory depression of baroreceptors in dogs with experimental heart failure. The American journal of physiology, 1991, Volume: 260, Issue:4 Pt 2 Topics: Animals; Cardiac Output; Carotid Sinus; Dogs; Female; Heart Failure; Heart Rate; Heart Ventricles; Hemodynamics; Male; Ouabain; Pressoreceptors; Pressure; Sodium-Potassium-Exchanging ATPase	1991
Carotid sinus baroreceptor sensitivity in experimental heart failure. Circulation, 1990, Volume: 81, Issue:6 Topics: Animals; Carotid Sinus; Compliance; Dogs; Female; Heart Failure; Male; Ouabain; Potassium; Pressoreceptors	1990
[Cardiodigin--endogenous digitalis? Unconventional comments on an old therapeutic principle]. Klinische Wochenschrift, 1985, Dec-16, Volume: 63, Issue:24 Topics: Biological Products; Cardiac Glycosides; Digitalis Glycosides; Dose-Response Relationship, Drug; Heart Failure; Humans; Myocardial Contraction; Ouabain; Sodium-Potassium-Exchanging ATPase	1985
Additive positive inotropic effects of milrinone, ouabain and calcium in diseased human ventricular myocardium. Klinische Wochenschrift, 1986, Aug-01, Volume: 64, Issue:15 Topics: Adult; Calcium; Cardiomyopathies; Cardiotonic Agents; Female; Heart Failure; Humans; Male; Middle Aged; Milrinone; Myocardial Contraction; Ouabain; Papillary Muscles; Pyridones; Rheumatic Heart Disease	1986
Effects of amrinone on contraction and K+-induced contracture of normal and subacutely failed cat ventricular muscle. Circulation, 1986, Volume: 73, Issue:3 Pt 2 Topics: Aminopyridines; Amrinone; Animals; Cardiotonic Agents; Cats; Dogs; Dose-Response Relationship, Drug; Guinea Pigs; Heart Failure; Hemodynamics; Isoproterenol; Myocardial Contraction; Nadolol; Ouabain; Potassium; Propanolamines	1986
[The use of digitalis drugs in cardiac patients]. Atlas de radiologie clinique de la Presse medicale, 1969, May-31, Volume: 56 Topics: Atrial Flutter; Calcium; Cardiac Complexes, Premature; Digitalis Glycosides; Digitoxin; Digoxin; Heart Failure; Humans; Lanatosides; Long-Term Care; Ouabain; Quinidine; Tachycardia	1969
Myofibrillar adenosine triphosphatase activity of human heart tissue in congestive failure: effects of ouabain and calcium. Circulation research, 1966, Volume: 18, Issue:5 Topics: Adenosine Triphosphatases; Adolescent; Adult; Aged; Calcium; Child; Child, Preschool; Heart Failure; Humans; In Vitro Techniques; Infant; Middle Aged; Myocardium; Myofibrils; Ouabain	1966
[Biochemical aspects of digitalis therapy]. Zeitschrift fur die gesamte innere Medizin und ihre Grenzgebiete, 1971, Feb-01, Volume: 26, Issue:3 Topics: Adenosine Triphosphatases; Animals; Anura; Biotransformation; Brain; Calcium; Cardanolides; Cats; Chemistry Techniques, Analytical; Depression, Chemical; Digitalis Glycosides; Digitoxin; Dogs; Drug Synergism; Heart; Heart Diseases; Heart Failure; Humans; Liver; Myocardium; Ouabain; Potassium; Rabbits; Rats; Stimulation, Chemical; Time Factors	1971
Sarcolemmal and sarcoplasmic reticular ATPase activities in the failing canine heart. Circulation research, 1971, Volume: 29, Issue:1 Topics: Adenosine Triphosphatases; Animals; Azides; Biological Transport; Calcium; Cardiac Output; Cardiomegaly; Cell Membrane; Chemical Phenomena; Chemistry; Dogs; Endoplasmic Reticulum; Female; Heart Failure; Magnesium; Male; Muscles; Myocardium; Myofibrils; Ouabain; Potassium; Pulmonary Valve Stenosis; Sarcolemma; Sodium; Succinate Dehydrogenase	1971
Depressed Na-K-ATPase activity in the failing rabbit heart. Japanese heart journal, 1972, Volume: 13, Issue:1 Topics: Adenosine Triphosphatases; Animals; Azides; Blood Pressure; Depression, Chemical; Dinitrophenols; Heart; Heart Failure; Heart Ventricles; Hypertrophy; Magnesium; Male; Myocardium; Oligomycins; Organ Size; Ouabain; Potassium; Rabbits; Sodium; Stimulation, Chemical	1972
Alterations in the activity of cardiac Na + -K + -stimulated ATPase in congestive heart failure. Experimental and molecular pathology, 1973, Volume: 18, Issue:1 Topics: Adenosine Triphosphatases; Animals; Calcium; Cell Membrane; Cricetinae; Heart; Heart Failure; Hydrogen; Magnesium; Male; Myocardium; Ouabain; Potassium; Sodium; Stimulation, Chemical	1973
Effects of oxyfedrine and ouabain on the heart-lung preparation of the dog. Naunyn-Schmiedeberg's archives of pharmacology, 1973, Volume: 277, Issue:1 Topics: Amino Alcohols; Animals; Arrhythmias, Cardiac; Cardiac Output; Disease Models, Animal; Dogs; Female; Heart; Heart Failure; In Vitro Techniques; Male; Ouabain; Pentobarbital; Phenethylamines; Propiophenones; Propranolol; Reserpine; Ventricular Fibrillation	1973
Drug therapy of heart disease in pediatric patients. II. The treatment of congestive heart failure in infants and children with digitalis preparations. American heart journal, 1973, Volume: 86, Issue:2 Topics: Adenosine Triphosphatases; Adolescent; Adult; Age Factors; Animals; Calcium; Cell Membrane; Child; Child, Preschool; Digitalis; Digitalis Glycosides; Digoxin; Heart Failure; Humans; Infant; Infant, Newborn; Infant, Newborn, Diseases; Kidney Diseases; Myocardium; Ouabain; Plants, Medicinal; Plants, Toxic; Sodium; Tritium	1973
Biochemical basis of heart function. X. Reduction in the Na+-K+-stimulated ATPase activity in failing rat heart due to hypoxia. Canadian journal of physiology and pharmacology, 1973, Volume: 51, Issue:7 Topics: Adenosine Triphosphatases; Adenosine Triphosphate; Aerobiosis; Anaerobiosis; Animals; Heart; Heart Failure; Hydrogen-Ion Concentration; Hypoxia; In Vitro Techniques; Male; Myocardium; Organ Size; Osmolar Concentration; Ouabain; Perfusion; Phosphates; Potassium; Rats; Sodium; Time Factors	1973
Catecholamine, protein, and RNA content in advanced congestive heart failure in the Syrian hamster. Recent advances in studies on cardiac structure and metabolism, 1972, Volume: 1 Topics: Animals; Cardiomegaly; Cricetinae; Dihydroxyphenylalanine; Disease Models, Animal; Dopamine; Heart; Heart Failure; Heart Rate; Male; Muscle Proteins; Myocardial Contraction; Norepinephrine; Organ Size; Ouabain; RNA	1972
Drug effects on cardiac myosin adenosine triphosphatase activity. The Journal of pharmacology and experimental therapeutics, 1967, Volume: 158, Issue:3 Topics: Adenosine Triphosphatases; Adenosine Triphosphate; Angiotensin II; Animals; Binding Sites; Calcium; Chloralose; Cyclopropanes; Digoxin; Dogs; Epinephrine; Ethers; Heart; Heart Failure; In Vitro Techniques; Isoproterenol; Lidocaine; Magnesium; Muscle Contraction; Muscle Proteins; Myocardium; Nitrous Oxide; Norepinephrine; Ouabain; Pentobarbital; Pharmacology; Procainamide; Protein Binding; Quinidine; Secobarbital	1967
An effect of ouabain on isolated heart tissue from cardiomyopathic Syrian hamsters. Journal of molecular and cellular cardiology, 1972, Volume: 4, Issue:5 Topics: Animals; Cricetinae; Electron Transport Complex IV; Guinea Pigs; Heart; Heart Diseases; Heart Failure; Kinetics; Manometry; Myocardium; Ouabain; Oxygen Consumption; Polarography; Species Specificity; Stimulation, Chemical; Subcellular Fractions; Tritium	1972
[Antiarrhythmic effect of sviomarin in experimental and clinical glycoside poisoning]. Zeitschrift fur Kreislaufforschung, 1969, Volume: 58, Issue:6 Topics: Animals; Arrhythmias, Cardiac; Digitalis Glycosides; Diphenhydramine; Dogs; Electrocardiography; Female; Heart Failure; Histamine H1 Antagonists; Humans; Injections, Intramuscular; Injections, Intravenous; Lidocaine; Male; Ouabain; Theophylline	1969
Effects of chronic heart failure on the inotropic response of the right ventricle of the conscious dog to a cardiac glycoside and to tachycardia. Circulation, 1974, Volume: 50, Issue:4 Topics: Animals; Blood Pressure; Dogs; Heart; Heart Failure; Heart Rate; Heart Ventricles; Isoproterenol; Ouabain; Pulmonary Valve Stenosis; Tachycardia; Tricuspid Valve Insufficiency; Ultrasonics	1974
[Reasons for prophylactic digitalization]. Klinicheskaia meditsina, 1974, Volume: 52, Issue:3 Topics: Cardiac Glycosides; Digoxin; Heart Failure; Humans; Myocardium; Ouabain; Postoperative Complications; Preoperative Care; Strophanthins	1974
Importance of the adrenergic nervous system in the support of cardiac function in patients with primary arterial hypertension. Clinical science and molecular medicine. Supplement, 1973, Volume: 45 Suppl 1 Topics: Body Weight; Cardiac Output; Chlorthalidone; Digitalis Glycosides; Glomerular Filtration Rate; Guanethidine; Heart; Heart Failure; Humans; Hypertension; Ouabain; Receptors, Adrenergic; Reserpine; Sympathetic Nervous System; Sympatholytics	1973
Aortic velocity and acceleration measurements in the assessment of coronary heart disease. European journal of cardiology, 1974, Volume: 1, Issue:3 Topics: Acute Disease; Angina Pectoris; Aorta; Blood Flow Velocity; Blood Pressure Determination; Cardiac Catheterization; Cardiac Output; Coronary Artery Bypass; Coronary Disease; Electrocardiography; Female; Glucagon; Heart Conduction System; Heart Failure; Heart Ventricles; Humans; Male; Mitral Valve Insufficiency; Myocardial Infarction; Ouabain; Prognosis; Regional Blood Flow	1974
Reversal of ouabain and acetyl strophanthidin effects in normal and failing cardiac muscle by specific antibody. The Journal of clinical investigation, 1974, Volume: 53, Issue:6 Topics: Animals; Antibodies; Cardanolides; Cats; Depression, Chemical; Digitalis Glycosides; Heart; Heart Failure; Heart Ventricles; Humans; Immunologic Techniques; In Vitro Techniques; Myocardium; Ouabain; Papillary Muscles; Pulmonary Artery; Rabbits; Serum Albumin; Stimulation, Chemical; Stress, Mechanical; Time Factors	1974
Ouabain-induced hypertension in a patient with decompensated hypertensive heart disease. Chest, 1973, Volume: 63, Issue:1 Topics: Aphasia; Cerebrovascular Disorders; Heart Failure; Hemiplegia; Hemodynamics; Humans; Hypertension; Hypertension, Pulmonary; Injections, Intravenous; Male; Middle Aged; Ouabain	1973
Clinical experience with ouabain administered in small divided doses in the monitored patient. Chest, 1973, Volume: 63, Issue:6 Topics: Administration, Oral; Arrhythmias, Cardiac; Atrial Fibrillation; Atrial Flutter; Digoxin; Electrocardiography; Heart Failure; Humans; Injections, Intravenous; Monitoring, Physiologic; Myocardial Infarction; Ouabain; Tachycardia, Paroxysmal	1973
The influence of the position of attachment of the lactone ring to the steroid nucleus on the action of cardiac glycosides. The Journal of pharmacology and experimental therapeutics, 1974, Volume: 188, Issue:1 Topics: Animals; Blood Pressure; Blood Volume; Cardanolides; Cardiac Glycosides; Cardiac Output; Dogs; Female; Glucose; Heart Conduction System; Heart Failure; Heart Rate; Lactones; Male; Ouabain; Pentobarbital; Stimulation, Chemical; Structure-Activity Relationship	1974
The onset and magnitude of the contractile response to commonly used digitalis glycosides in normal subjects. Circulation, 1974, Volume: 49, Issue:3 Topics: Adult; Digoxin; Dose-Response Relationship, Drug; Heart Failure; Heart Rate; Humans; Injections, Intravenous; Lanatosides; Male; Ouabain; Strophanthins; Time Factors	1974
Pacemaker-ventricular blocks. Acta medica Scandinavica, 1974, Volume: 195, Issue:4 Topics: Aged; Digoxin; Female; Heart Block; Heart Failure; Heart Rate; Humans; Lidocaine; Male; Myocardial Infarction; Ouabain; Pacemaker, Artificial; Quinidine	1974
Intracellular calcium and myocardial contractility. V. Calcium uptake of sarcoplasmic reticulum fractions in hypertrophied and failing rabbit hearts. Journal of molecular and cellular cardiology, 1974, Volume: 6, Issue:3 Topics: Animals; Azides; Biological Transport; Body Weight; Calcium; Calcium Radioisotopes; Cardiomyopathies; Electrocardiography; Fumarate Hydratase; Heart; Heart Failure; Mitochondria, Muscle; Muscle Proteins; Myocardium; Organ Size; Ouabain; Rabbits; Sarcoplasmic Reticulum; Succinate Dehydrogenase; Time Factors	1974
The contribution of local factors to the elevated venous tone of congestive heart failure. The Journal of clinical investigation, 1974, Volume: 54, Issue:2 Topics: Adult; Blood Pressure; Blood Volume; Constriction; Ethacrynic Acid; Heart Failure; Humans; Injections, Intra-Arterial; Middle Aged; Nitrites; Ouabain; Phentolamine; Plethysmography; Sodium; Sodium Chloride; Veins	1974
Effect of ouabain on insulin secretion in man. Clinical science, 1972, Volume: 42, Issue:1 Topics: Adult; Blood Glucose; Catecholamines; Heart Failure; Humans; Injections, Intravenous; Insulin; Insulin Secretion; Male; Middle Aged; Norepinephrine; Ouabain; Secretory Rate; Tolbutamide	1972
Regional hemodynamic effects of a digitalis glycoside in the conscious dog with and without experimental heart failure. Circulation research, 1972, Volume: 30, Issue:4 Topics: Anesthesia; Animals; Atropine; Blood Flow Velocity; Blood Pressure; Dogs; Heart Failure; Heart Rate; Hemodynamics; Iliac Artery; Ilium; Kidney; Mesenteric Arteries; Mesentery; Ouabain; Regional Blood Flow; Renal Artery; Time Factors; Ultrasonics; Vascular Resistance; Vasomotor System	1972
Experimental studies on the influence of ouabain on ATP, calcium and magnesium in the failing human heart. European journal of clinical investigation, 1972, Volume: 2, Issue:2 Topics: Adenosine Triphosphate; Arteries; Calcium; Cardiac Catheterization; Coronary Vessels; Heart Failure; Humans; Magnesium; Myocardium; Ouabain; Veins	1972
Digitalis and the mesenteric circulation. The American journal of digestive diseases, 1972, Volume: 17, Issue:9 Topics: Digitalis Glycosides; Heart Failure; Humans; Intestines; Ischemia; Mesenteric Arteries; Mesenteric Vascular Occlusion; Ouabain; Vascular Resistance	1972
The effect of diphenylhydantoin sodium given with cardiac glycosides on the left ventricular systole dynamics. Polish medical journal, 1970, Volume: 9, Issue:2 Topics: Adult; Animals; Dogs; Heart Conduction System; Heart Failure; Humans; Lanatosides; Ouabain; Phenytoin; Sodium	1970
Persistence of low cardiac output after relief of high output by thiamine in a case of alcoholic beriberi and cardiac myopathy. American heart journal, 1970, Volume: 80, Issue:1 Topics: Adult; Alcoholism; Beriberi; Cardiac Output; Exercise Therapy; Heart Failure; Humans; Male; Myocardium; Ouabain; Oxygen Consumption; Thiamine	1970
[Studies on the effect of peruvoside on heart function in animal experiments]. Arzneimittel-Forschung, 1968, Volume: 18, Issue:12 Topics: Animals; Arrhythmias, Cardiac; Arteries; Barbiturates; Blood Circulation; Blood Pressure; Cardiac Glycosides; Cats; Coronary Vessels; Dogs; Electrocardiography; Female; Guinea Pigs; Heart; Heart Conduction System; Heart Failure; Heart Function Tests; Heart Rate; Heart Ventricles; Male; Ouabain; Phenylbutazone; Stimulation, Chemical; Vascular Resistance	1968
[After-contractions as a cause of late diastolic "tonus increase" of the heart. Studies of diastolic extensibility of the isolated frog heart under propranolol, hexobarbital and k-strophanthin]. Zeitschrift fur Kreislaufforschung, 1969, Volume: 58, Issue:1 Topics: Animals; Cardiac Output; Cardiac Volume; Heart; Heart Failure; Heart Function Tests; Hexobarbital; Myography; Ouabain; Propranolol	1969
Digitalis and the cardiac glycosides. British medical journal, 1969, Jun-21, Volume: 2, Issue:5659 Topics: Atrial Fibrillation; Atrial Flutter; Cardiovascular System; Digitalis Glycosides; Heart Failure; Heart Rate; Humans; Ouabain; Tachycardia, Paroxysmal	1969
Cardiac and peripheral vascular effects of digitalis in clinical cardiogenic shock. American heart journal, 1969, Volume: 78, Issue:3 Topics: Blood Pressure; Cardiac Glycosides; Cardiac Output; Digoxin; Heart Failure; Heart Function Tests; Hemodynamics; Humans; Infusions, Parenteral; Lanatosides; Male; Middle Aged; Ouabain; Shock; Vascular Resistance; Vasoconstrictor Agents	1969