ouabain has been researched along with ADPKD in 10 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (10.00) | 18.2507 |
| 2000's | 1 (10.00) | 29.6817 |
| 2010's | 7 (70.00) | 24.3611 |
| 2020's | 1 (10.00) | 2.80 |
| Authors | Studies |
|---|---|
| Blanco, G; McDermott, JP; Sanchez, G; Trant, J | 1 |
| Barbosa, L; Blanco, G; McDermott, J; Reif, GA; Sanchez, G; Sharma, M; Venugopal, J; Wallace, DP | 1 |
| Blanco, G; Venugopal, J | 1 |
| Blanco, G; Wallace, DP | 1 |
| Blanco, G; Calvet, JP; Jansson, K; Magenheimer, BS; Maser, RL | 1 |
| Blanco, G; Calvet, JP; Jansson, K; Magenheimer, BS; Reif, GA; Sánchez, G; Venugopal, J; Wallace, DP | 1 |
| Blanco, G; Jansson, K; Nguyen, AN; Reif, GA; Sánchez, G; Sharma, M; Wallace, DP | 1 |
| Aramadhaka, LR; Bello-Reuss, E; Blanco, G; Calvet, JP; Jansson, K; Magenheimer, BS; Nguyen, AN; Reif, GA; Wallace, DP | 1 |
| Blanco, G; Nguyen, AN; Wallace, DP | 1 |
| Gattone, VH; Grantham, JJ; Sullivan, LP; Ye, M | 1 |
2 review(s) available for ouabain and ADPKD
| Article | Year |
|---|---|
On the Many Actions of Ouabain: Pro-Cystogenic Effects in Autosomal Dominant Polycystic Kidney Disease.
Topics: Animals; Cardiotonic Agents; Cell Communication; Humans; Kidney; Ouabain; Polycystic Kidney, Autosomal Dominant; Signal Transduction | 2017 |
Novel role of ouabain as a cystogenic factor in autosomal dominant polycystic kidney disease.
Topics: Animals; Apoptosis; Cell Proliferation; Humans; Kidney; Kidney Tubules; Natriuretic Agents; Ouabain; Polycystic Kidney, Autosomal Dominant; Signal Transduction; Sodium-Potassium-Exchanging ATPase; TRPP Cation Channels | 2013 |
8 other study(ies) available for ouabain and ADPKD
| Article | Year |
|---|---|
Ouabain enhances renal cyst growth in a slowly progressive mouse model of autosomal dominant polycystic kidney disease.
Topics: Adenosine Triphosphatases; Animals; Cysts; Disease Models, Animal; Female; Hormones; Kidney; Male; Mice; Ouabain; Polycystic Kidney, Autosomal Dominant; TRPP Cation Channels | 2023 |
Ouabain promotes partial epithelial to mesenchymal transition (EMT) changes in human autosomal dominant polycystic kidney disease (ADPKD) cells.
Topics: Adult; Aged; Cell Adhesion; Cell Movement; Epithelial-Mesenchymal Transition; Female; Humans; Male; Middle Aged; Ouabain; Polycystic Kidney, Autosomal Dominant; Structure-Activity Relationship | 2017 |
Overexpression of the polycystin-1 C-tail enhances sensitivity of M-1 cells to ouabain.
Topics: Animals; Anions; Cell Line; Cell Proliferation; Colforsin; Drug Resistance; ErbB Receptors; Gene Expression; Kidney Tubules, Collecting; MAP Kinase Signaling System; Mice; Ouabain; Polycystic Kidney, Autosomal Dominant; Protein Interaction Domains and Motifs; Proto-Oncogene Proteins pp60(c-src); TRPP Cation Channels | 2013 |
Ouabain Regulates CFTR-Mediated Anion Secretion and Na,K-ATPase Transport in ADPKD Cells.
Topics: Animals; Anions; Biological Transport; Cell Membrane; Chlorides; Colforsin; Cystic Fibrosis Transmembrane Conductance Regulator; Disease Models, Animal; Gene Knockout Techniques; Intracellular Signaling Peptides and Proteins; Membrane Proteins; Mice; Mice, Knockout; Organ Culture Techniques; Ouabain; Polycystic Kidney, Autosomal Dominant; Primary Cell Culture; Sodium-Potassium-Chloride Symporters; Sodium-Potassium-Exchanging ATPase | 2015 |
Ouabain activates the Na-K-ATPase signalosome to induce autosomal dominant polycystic kidney disease cell proliferation.
Topics: beta-Cyclodextrins; Caveolin 1; Cell Proliferation; Cells, Cultured; Cyclin-Dependent Kinase Inhibitor p21; Cyclin-Dependent Kinase Inhibitor p27; Enzyme Inhibitors; ErbB Receptors; Humans; MAP Kinase Kinase Kinases; Ouabain; Phosphorylation; Polycystic Kidney, Autosomal Dominant; Proto-Oncogene Proteins B-raf; Proto-Oncogene Proteins c-fyn; Pyrimidines; Quinazolines; Signal Transduction; Sodium-Potassium-Exchanging ATPase; src-Family Kinases; Tyrphostins | 2011 |
Endogenous concentrations of ouabain act as a cofactor to stimulate fluid secretion and cyst growth of in vitro ADPKD models via cAMP and EGFR-Src-MEK pathways.
Topics: Animals; Cell Proliferation; Cells, Cultured; Colforsin; Cyclic AMP; Cysts; Epithelial Cells; ErbB Receptors; Humans; Kidney; Mice; Ouabain; Polycystic Kidney, Autosomal Dominant; Signal Transduction | 2012 |
Ouabain binds with high affinity to the Na,K-ATPase in human polycystic kidney cells and induces extracellular signal-regulated kinase activation and cell proliferation.
Topics: Base Sequence; Cell Proliferation; Cells, Cultured; DNA Primers; Enzyme Inhibitors; Epithelial Cells; Humans; Isoenzymes; Kidney; MAP Kinase Signaling System; Ouabain; Polycystic Kidney, Autosomal Dominant; RNA, Messenger; Sodium-Potassium-Exchanging ATPase | 2007 |
In vitro fluid secretion by epithelium from polycystic kidneys.
Topics: Biological Transport; Cell Polarity; Cells, Cultured; Chlorides; Cyclic AMP; Cysts; Epithelium; Humans; In Vitro Techniques; Kidney; Membrane Potentials; Ouabain; Polycystic Kidney, Autosomal Dominant; Potassium; Sodium | 1995 |