osthol and Disease Models, Animal

Topics: Animals; Antiviral Agents; Artificial Intelligence; Chlorocebus aethiops; Disease Models, Animal; Drug Evaluation, Preclinical; High-Throughput Screening Assays; Immunocompetence; Inhibitory Concentration 50; Methacycline; Mice, Inbred C57BL; Protease Inhibitors; Quantitative Structure-Activity Relationship; Small Molecule Libraries; Vero Cells; Zika Virus; Zika Virus Infection

Topics: Animals; Antibiotics, Antineoplastic; Bleomycin; Cell Differentiation; Cell Proliferation; Coumarins; Disease Models, Animal; Humans; Idiopathic Pulmonary Fibrosis; Lung; Male; Mice; Mice, Inbred C57BL; Myofibroblasts; NADPH Oxidase 4; Oxidative Stress; Reactive Oxygen Species; Smad3 Protein; Survival Rate; Transforming Growth Factor beta1

Topics: Animals; Cell Proliferation; Coumarins; Disease Models, Animal; Lipids; MicroRNAs; Myocytes, Smooth Muscle; Pulmonary Artery; Rats; Rats, Sprague-Dawley; Vascular Remodeling

Topics: Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; Disease Models, Animal; Endoplasmic Reticulum Stress; Endoribonucleases; Humans; Mice; Mice, Transgenic; Neuroblastoma; Plaque, Amyloid; Protein Serine-Threonine Kinases

Topics: Alzheimer Disease; Amyloid beta-Protein Precursor; Animals; Apoptosis; Coumarins; Disease Models, Animal; Glutamic Acid; Mice; Mice, Transgenic; Neuroprotection; NF-E2-Related Factor 2; Oxidative Stress; Presenilin-1; Signal Transduction

Topics: Animals; Carcinogenesis; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Proliferation; Coumarins; Disease Models, Animal; Disease Progression; Drug Screening Assays, Antitumor; Extracellular Signal-Regulated MAP Kinases; Fatty Acid Synthase, Type I; Fatty Liver; Female; Humans; Lipogenesis; Liver; Liver Neoplasms; Mice; Phosphorylation; Proto-Oncogene Proteins c-akt; Signal Transduction; Time Factors

Topics: Adjuvants, Immunologic; Angelica; Animals; Cells, Cultured; Cornea; Corneal Neovascularization; Coumarins; Disease Models, Animal; Humans; Male; Medicine, Chinese Traditional; Mice; Mice, Inbred ICR

Topics: Alzheimer Disease; Amyloid beta-Protein Precursor; Animals; Cognitive Dysfunction; Coumarins; Disease Models, Animal; Humans; Maze Learning; Mice; Mice, Inbred C57BL; Mice, Transgenic; Neurons

Topics: Animals; Coumarins; Disease Models, Animal; Down-Regulation; Lysophospholipids; Male; MicroRNAs; Phosphatidylinositol 3-Kinases; Phosphotransferases (Alcohol Group Acceptor); Proto-Oncogene Proteins c-akt; Pulmonary Arterial Hypertension; Rats; Rats, Sprague-Dawley; Sphingosine; TOR Serine-Threonine Kinases

Topics: Animals; Asthma; Bronchial Hyperreactivity; Bronchoalveolar Lavage Fluid; Coumarins; Disease Models, Animal; Drugs, Chinese Herbal; Female; Gene Expression Regulation; Inflammation; Interferon-gamma; Interleukin-1 Receptor-Like 1 Protein; Interleukin-33; Interleukins; Lung; Lymphocyte Count; Mice; Mice, Inbred BALB C; Ovalbumin; Phytotherapy; Pulmonary Eosinophilia; Random Allocation; RNA, Messenger; Signal Transduction

Topics: Administration, Oral; Amyloid beta-Peptides; Animals; Behavior Observation Techniques; Behavior, Animal; Brain; Cognitive Dysfunction; Coumarins; Dementia, Vascular; Disease Models, Animal; Dose-Response Relationship, Drug; Humans; Inflammasomes; Male; NLR Family, Pyrin Domain-Containing 3 Protein; Rats

Topics: Animals; Behavior, Animal; Calcium Channel Blockers; Coumarins; Disease Models, Animal; Male; Memory Disorders; Neurons; Neuroprotective Agents; Oxidative Stress; Rats; Rats, Wistar; Sleep Deprivation

Topics: Adaptor Proteins, Signal Transducing; Animals; bcl-2-Associated X Protein; Calcium Channel Blockers; Caspase 3; Coumarins; Disease Models, Animal; Hypertension, Pulmonary; Lung; MAP Kinase Kinase Kinase 5; Myocytes, Smooth Muscle; Organ Size; Pulmonary Artery; Rats; Signal Transduction; Treatment Outcome; Up-Regulation

Topics: Animals; Anti-Inflammatory Agents; Blood Pressure; Coumarins; Disease Models, Animal; Hypertension, Pulmonary; Lung; Male; Monocrotaline; NF-kappa B; Organ Size; Pulmonary Artery; Rats, Sprague-Dawley

Topics: Animals; Anti-Inflammatory Agents; Biomarkers; Biopsy; Chemokine CCL2; Coumarins; Cytokines; Disease Models, Animal; Gene Expression Regulation; Histocytochemistry; Inflammation Mediators; Kidney Failure, Chronic; Kidney Function Tests; Male; NF-E2-Related Factor 2; NF-kappa B; Phosphatidylinositol 3-Kinases; Rats; Signal Transduction; Transforming Growth Factor beta1

Topics: Administration, Oral; Animals; Antifungal Agents; Candida albicans; Candidiasis; Coumarins; Disease Models, Animal; Drug Carriers; Drug Synergism; Fluconazole; Mice; Plasma; Polymethacrylic Acids; Treatment Outcome

Topics: Animals; Antioxidants; Benzenesulfonates; Colitis; Coumarins; Cytokines; Disease Models, Animal; Male; Oxidative Stress; Rats, Sprague-Dawley

Topics: Animals; Anti-Bacterial Agents; Carbapenem-Resistant Enterobacteriaceae; Coumarins; Disease Models, Animal; Drug Resistance, Bacterial; Drug Synergism; Enzyme Inhibitors; Escherichia coli Infections; Ethanolaminephosphotransferase; Female; Klebsiella Infections; Mice, Inbred BALB C; Microbial Sensitivity Tests; Microbial Viability; Molecular Docking Simulation; Polymyxins; Treatment Outcome

Topics: Animals; Anti-Inflammatory Agents; Cnidium; Colitis, Ulcerative; Coumarins; Dinoprostone; Disease Models, Animal; Mice; Mice, Inbred BALB C; NF-kappa B; NF-KappaB Inhibitor alpha; Nitric Oxide; p38 Mitogen-Activated Protein Kinases; RAW 264.7 Cells; Signal Transduction; Tumor Necrosis Factor-alpha

Topics: Alzheimer Disease; Amyloid beta-Protein Precursor; Animals; Calcium Channel Blockers; Coumarins; Disease Models, Animal; Gene Expression Regulation; Humans; Maze Learning; Mice; Mice, Inbred C57BL; Mice, Transgenic; MicroRNAs; Neuroblastoma; Presenilin-1; Tumor Cells, Cultured; Up-Regulation

Topics: Administration, Topical; Animals; Coumarins; Cymenes; Dermatitis, Atopic; Dinitrofluorobenzene; Disease Models, Animal; Dose-Response Relationship, Drug; Hot Temperature; Humans; Interleukin-6; Male; Mice; TRPV Cation Channels; Tumor Necrosis Factor-alpha; Up-Regulation

Topics: Acute Kidney Injury; Animals; Calcium Channel Blockers; Coumarins; Disease Models, Animal; Gene Expression Regulation, Enzymologic; Inflammation; Interleukin-1beta; Kidney; Male; Monocytes; p38 Mitogen-Activated Protein Kinases; Peroxidase; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Tumor Necrosis Factor-alpha

Topics: Animals; Antioxidants; Coumarins; Disease Models, Animal; Intestines; Male; Mice; Neutrophil Infiltration; NF-kappa B; Nitric Oxide; Oxidative Stress; Reperfusion Injury; Signal Transduction

Topics: Acute Lung Injury; Animals; Bronchoalveolar Lavage Fluid; Calcium Channel Blockers; Cell Line, Transformed; Cell Survival; Coumarins; Disease Models, Animal; Dose-Response Relationship, Drug; Lipopolysaccharides; Male; Mice; Mice, Inbred BALB C; NF-E2-Related Factor 2; Organ Size; Oxidative Stress; Reactive Oxygen Species; RNA, Messenger; RNA, Small Interfering; Statistics, Nonparametric; Survival Analysis; Thioredoxins; Time Factors; Transfection; Up-Regulation

Topics: Animals; Calcium Channel Blockers; Catalase; Coumarins; Cytokines; Disease Models, Animal; Enzyme Activation; Hemodynamics; HMGB1 Protein; Inflammation Mediators; Lipid Peroxidation; Male; Myocardial Reperfusion Injury; Myocardium; NF-kappa B; Oxidative Stress; Rats; Superoxide Dismutase

Topics: Animals; Anti-Inflammatory Agents; Bone Marrow Transplantation; Cell Differentiation; Cells, Cultured; Coumarins; Demyelinating Diseases; Disease Models, Animal; Encephalomyelitis, Autoimmune, Experimental; Female; Graft Survival; Humans; Mice; Mice, Inbred C57BL; Mice, Transgenic; Multiple Sclerosis; Myelin Sheath; Neural Stem Cells; Neurons; Neuroprotective Agents; Oligodendroglia; Stem Cell Transplantation

Topics: Acute Lung Injury; Animals; Blood Pressure; Calcium Channel Blockers; Coumarins; Disease Models, Animal; Interleukin-6; Lung; Male; Malondialdehyde; Organ Size; Oxidative Stress; Peroxidase; Pulmonary Gas Exchange; Rats; Rats, Wistar; Reactive Oxygen Species; Reperfusion Injury; Superoxide Dismutase; Tumor Necrosis Factor-alpha

Topics: Active Transport, Cell Nucleus; Animals; Antioxidants; Apoptosis; Calcium Channel Blockers; Cnidium; Coumarins; Cyclooxygenase 2; Dinoprostone; Disease Models, Animal; Female; Glomerulosclerosis, Focal Segmental; Glutathione Peroxidase; Heme Oxygenase-1; Inflammation; Macrophage Activation; Macrophages; Membrane Proteins; Mice; Mice, Inbred BALB C; NF-E2-Related Factor 2; NF-kappa B; Oxidative Stress; Plant Preparations; Podocytes; Proteinuria; Reactive Oxygen Species

Topics: Animals; Antioxidants; Biomarkers; Coumarins; Cytoprotection; Disease Models, Animal; Ileum; Injections, Intravenous; Male; Mesenteric Ischemia; Mesenteric Vascular Occlusion; Mice; Oxidative Stress; Permeability; Reperfusion Injury

Topics: Animals; Biomarkers; Coumarins; Diet, High-Fat; Disease Models, Animal; Insulin Resistance; Liver; Non-alcoholic Fatty Liver Disease; Rats, Sprague-Dawley; Time Factors; Triglycerides

Topics: Analysis of Variance; Animals; Brain Edema; Brain Injuries; Caspase 3; Cerebral Cortex; Coumarins; Cytokines; Disease Models, Animal; Dose-Response Relationship, Drug; Encephalitis; In Situ Nick-End Labeling; Mice; Mice, Inbred C57BL; Nerve Tissue Proteins; Neurologic Examination; Neuroprotective Agents; Peroxidase; RNA, Messenger; Time Factors

Topics: Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; Avoidance Learning; Behavior, Animal; Brain-Derived Neurotrophic Factor; Coumarins; Cyclic AMP Response Element-Binding Protein; Disease Models, Animal; Hippocampus; Male; Maze Learning; Memory; Mice, Inbred C57BL; Mice, Transgenic; Neurogenesis; Neuroprotective Agents; Peptide Fragments; Presenilin-1; Up-Regulation

Topics: Adjuvants, Immunologic; Animals; Blotting, Western; Calcium Phosphates; Coumarins; Cytokines; Disease Models, Animal; Male; Mice; Mice, Inbred ICR; Osteoclasts; Osteolysis; Prostheses and Implants; Signal Transduction; Skull; Tartrate-Resistant Acid Phosphatase

Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Apoptosis; beta Catenin; Cell Differentiation; Cell Proliferation; Cells, Cultured; Coumarins; Disease Models, Animal; Mice; Mice, Inbred C57BL; Neural Stem Cells; Neurogenesis; Neurons; Wnt Signaling Pathway

Topics: Animals; Bone Resorption; Coumarins; Disease Models, Animal; Drugs, Chinese Herbal; Gene Expression Regulation; Male; Mice; Mice, Inbred C57BL; Nephrectomy; Osteoblasts; Osteoclasts; Osteoprotegerin; RANK Ligand

Topics: Animals; Blotting, Western; Cardiomyopathies; Cells, Cultured; Collagen Type I; Collagen Type III; Coumarins; Disease Models, Animal; Fibroblasts; Fibrosis; Gene Expression Regulation; Mice; Myocardium; Real-Time Polymerase Chain Reaction; RNA, Messenger; Signal Transduction; Smad2 Protein; Transforming Growth Factor beta1

Topics: A549 Cells; Animals; Bacterial Toxins; Coumarins; Disease Models, Animal; Drug Therapy, Combination; Flavonoids; Gene Expression Regulation, Bacterial; Hemolysin Proteins; Humans; Methicillin-Resistant Staphylococcus aureus; Mice; Microbial Sensitivity Tests; Pneumonia, Staphylococcal

Topics: Acute Kidney Injury; Animals; Anti-Inflammatory Agents; Coumarins; Disease Models, Animal; Dose-Response Relationship, Drug; Down-Regulation; Gene Expression Regulation; Humans; Macrophages; Male; Mice; NF-kappa B; RAW 264.7 Cells; Sepsis; Signal Transduction; Treatment Outcome

Topics: Analgesics; Angelica; Animals; Chromatography, High Pressure Liquid; Coumarins; Disease Models, Animal; Dose-Response Relationship, Drug; Extracellular Signal-Regulated MAP Kinases; Ganglia, Spinal; Inflammation Mediators; Male; Neuralgia; Pain Threshold; Phosphorylation; Phytotherapy; Plant Roots; Plants, Medicinal; Rats, Sprague-Dawley; Signal Transduction; Time Factors; TRPV Cation Channels

Topics: Animals; Anti-Asthmatic Agents; Asthma; Bronchoalveolar Lavage Fluid; Coumarins; Cytokines; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Immunoglobulin E; Mice; NF-kappa B; Ovalbumin

Topics: Animals; Anticonvulsants; Coumarins; Disease Models, Animal; Dose-Response Relationship, Drug; Electroshock; Injections, Intraperitoneal; Male; Mice; Seizures; Time Factors

Topics: Animals; Cholesterol 7-alpha-Hydroxylase; Cnidium; Coumarins; Diacylglycerol O-Acyltransferase; Disease Models, Animal; Dose-Response Relationship, Drug; Fatty Liver, Alcoholic; Fruit; Gene Expression; Hepatocytes; Hydroxymethylglutaryl CoA Reductases; Hypolipidemic Agents; Liver; Male; Mice; Mice, Inbred Strains; Phytotherapy; PPAR alpha; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger

Topics: Animals; Cholesterol; Cholesterol, LDL; Cnidium; Coumarins; Cytochrome P-450 CYP2E1; Diacylglycerol O-Acyltransferase; Disease Models, Animal; Fatty Liver, Alcoholic; Fruit; Lipid Metabolism; Lipid Peroxidation; Liver; Male; Malondialdehyde; Mice; Oxidative Stress; Superoxide Dismutase; Time Factors; Triglycerides

Topics: Animals; Calcium Channel Blockers; Cerebral Infarction; Chromatography, High Pressure Liquid; Coumarins; Disease Models, Animal; Humans; Male; Rats; Rats, Wistar; Solid Phase Microextraction

Topics: Analgesics; Animals; Behavior, Animal; Coumarins; Cyclooxygenase 2; Disease Models, Animal; Ganglia, Spinal; Injections, Epidural; Intervertebral Disc Displacement; Lumbar Vertebrae; Male; Nitric Oxide Synthase; Pain Measurement; Pain Threshold; Random Allocation; Rats; Rats, Sprague-Dawley; Sciatica; Spinal Nerve Roots

Topics: Animals; Anti-Inflammatory Agents; Catheterization; Coumarins; Cyclooxygenase 2; Disease Models, Animal; Injections, Epidural; Intervertebral Disc Displacement; Lumbar Vertebrae; Male; Nitric Oxide Synthase; Pain; Rats; Rats, Sprague-Dawley; Sciatica

Topics: Alanine Transaminase; Animals; Antibodies; Apoptosis; Caspase 3; Caspases; Chemical and Drug Induced Liver Injury; Coumarins; Disease Models, Animal; fas Receptor; Female; Mice; Mice, Inbred BALB C

Topics: Androgens; Animals; Cnidium; Coumarins; Disease Models, Animal; Drugs, Chinese Herbal; Follicle Stimulating Hormone; Gonadotropins; Luteinizing Hormone; Male; Nitric Oxide; Nitric Oxide Synthase; Orchiectomy; Rats; Rats, Wistar; Testosterone

Topics: Adjuvants, Immunologic; Animals; Coumarins; Disease Models, Animal; Fatty Acids, Nonesterified; Fatty Liver, Alcoholic; Glutathione; Lipid Metabolism; Liver; Male; Malondialdehyde; Mice; Organ Size; Superoxide Dismutase; Triglycerides; Tumor Necrosis Factor-alpha