orphenadrine has been researched along with Schizophrenia in 25 studies
Orphenadrine: A muscarinic antagonist used to treat drug-induced parkinsonism and to relieve pain from muscle spasm.
orphenadrine : A tertiary amino compound which is the phenyl-o-tolylmethyl ether of 2-(dimethylamino)ethanol.
Schizophrenia: A severe emotional disorder of psychotic depth characteristically marked by a retreat from reality with delusion formation, HALLUCINATIONS, emotional disharmony, and regressive behavior.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Orphenadrine is an antimuscarinic agent mainly used for the treatment of parkinsonism and to alleviate the neuroleptic syndrome induced by antipsychotic drugs." | 1.35 | Determination of orphenadrine plasma levels using HPLC with diode array detection and a novel solid-phase extraction procedure in psychiatric patients. ( Franchini, L; Petio, C; Raggi, MA; Saracino, MA; Vitali, M, 2009) |
| " We describe a case of acute dystonia with atypical onset without relation to changes in dosage and with laryngeal involvement with aphonia, but without dyspnoea." | 1.30 | [Atypical acute dystonia]. ( Mors, NP; Nielsen, AS, 1998) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 21 (84.00) | 18.7374 |
| 1990's | 3 (12.00) | 18.2507 |
| 2000's | 1 (4.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Saracino, MA | 1 |
| Petio, C | 1 |
| Vitali, M | 1 |
| Franchini, L | 1 |
| Raggi, MA | 1 |
| AVENARIUS, R | 1 |
| FISCHER, H | 1 |
| MEYER, JE | 1 |
| VERSTER, JP | 1 |
| PFEIFFER, CC | 1 |
| GOLDSTEIN, L | 1 |
| MURPHREE, HB | 1 |
| SUGERMAN, AA | 1 |
| Pullen, GP | 1 |
| Best, NR | 1 |
| Maguire, J | 1 |
| Johnson, DA | 1 |
| Pigache, RM | 1 |
| Nielsen, AS | 1 |
| Mors, NP | 1 |
| Gerlach, J | 1 |
| Rasmussen, PT | 1 |
| Hansen, L | 1 |
| Kristjansen, P | 1 |
| Cotes, PM | 1 |
| Crow, TJ | 1 |
| Johnstone, EC | 1 |
| Bartlett, W | 1 |
| Bourne, RC | 1 |
| Schifano, F | 1 |
| di Costanzo, E | 1 |
| Altamura, AC | 2 |
| Mauri, MC | 1 |
| De Novellis, F | 1 |
| Percudani, M | 1 |
| Vampini, V | 1 |
| Buccio, M | 1 |
| Colacurcio, F | 1 |
| Colombo, G | 1 |
| Terzi, A | 1 |
| Fleming, P | 1 |
| Makar, H | 1 |
| Hunter, KR | 1 |
| Bender, DA | 1 |
| Bamji, AN | 1 |
| Mindham, RH | 1 |
| Gaind, R | 1 |
| Anstee, BH | 1 |
| Rimmer, L | 1 |
| Morris, PA | 1 |
| MacKenzie, DH | 1 |
| Masheter, HC | 1 |
| Häfner, H | 2 |
| Schliack, E | 2 |
| Zenz, H | 2 |
| Dogliani, P | 1 |
| Senini, G | 1 |
| Bertuzzi, F | 1 |
| Schipper, JA | 1 |
| Silverman, M | 1 |
| Lopes, WP | 1 |
| Johnson, J | 1 |
| Milner, G | 1 |
| Ekdawi, MY | 1 |
| Fowke, R | 1 |
8 trials available for orphenadrine and Schizophrenia
| Article | Year |
|---|---|
Studies of depressive symptoms in schizophrenia.
Topics: Adolescent; Adult; Aged; Clinical Trials as Topic; Depressive Disorder; Double-Blind Method; Female; | 1981 |
Effects of placebo, orphenadrine, and rising doses of chlorpromazine, on PAT performance in chronic schizophrenia. A two year longitudinal study.
Topics: Adult; Attention; Chlorpromazine; Chronic Disease; Dominance, Cerebral; Dose-Response Relationship, | 1993 |
Antiparkinsonian agents and long-term neuroleptic treatment. Effect of G 31.406, orphenadrine, and placebo on parkinsonism, schizophrenic symptoms, depression and anxiety.
Topics: Administration, Oral; Adult; Aged; Antiparkinson Agents; Anxiety; Clinical Trials as Topic; Depressi | 1977 |
Neuroendocrine changes in acute schizophrenia as a function of clinical state and neuroleptic medication.
Topics: Acute Disease; Chlorpromazine; Clinical Trials as Topic; Double-Blind Method; Drug Therapy, Combinat | 1978 |
Levodopa in drug-induced extrapyramidal disorders.
Topics: Dihydroxyphenylalanine; Extrapyramidal Tracts; Fluphenazine; Humans; Movement Disorders; Orphenadrin | 1970 |
Comparison of amantadine, orphenadrine, and placebo in the control of phenothiazine-induced Parkinsonism.
Topics: Affect; Amantadine; Basal Ganglia Diseases; Clinical Trials as Topic; Evaluation Studies as Topic; F | 1972 |
A comparative double blind trial of pimozide and fluphenazine in chronic schizophrenia.
Topics: Benzimidazoles; Blood Cell Count; Clinical Trials as Topic; Fluphenazine; Humans; Male; Middle Aged; | 1970 |
[Depot-neuroleptics in the treatment of schizophrenia].
Topics: Adult; Chlorpromazine; Delayed-Action Preparations; Female; Fluphenazine; Haloperidol; Humans; Middl | 1971 |
17 other studies available for orphenadrine and Schizophrenia
| Article | Year |
|---|---|
Determination of orphenadrine plasma levels using HPLC with diode array detection and a novel solid-phase extraction procedure in psychiatric patients.
Topics: Antipsychotic Agents; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Drug M | 2009 |
[On the treatment of asymptomatic schizophrenia with very high doses of reserpine and orphenadrine].
Topics: Anti-Allergic Agents; Histamine H1 Antagonists; Orphenadrine; Parasympatholytics; Reserpine; Schizop | 1961 |
Investigations into the so-called reserpine Parkinsonoid in chronic schizophrenics and its treatment with orphenadrine (disipal).
Topics: Anticonvulsants; Humans; Orphenadrine; Parkinson Disease; Reserpine; Schizophrenia | 1959 |
PRELIMINARY REPORT ON THE TREATMENT OF MENTALLY DISORDERED PATIENTS BY INTRATHECALLY ADMINISTERED PHENOTHIAZINE DRUGS AND AN ANTISEROTONIN SUBSTANCE.
Topics: Anxiety; Anxiety Disorders; Bipolar Disorder; Catatonia; Ergot Alkaloids; Injections, Spinal; Mental | 1963 |
TIME-SERIES, FREQUENCY ANALYSIS, AND ELECTROGENESIS OF THE EEGS OF NORMALS AND PSYCHOTICS BEFORE AND AFTER DRUGS.
Topics: Amphetamine; Antidepressive Agents; Barbiturates; Biomedical Research; Caffeine; Central Nervous Sys | 1965 |
Anticholinergic drug abuse: a common problem?
Topics: Adult; Biperiden; Female; Humans; Male; Middle Aged; Orphenadrine; Parasympatholytics; Schizophrenia | 1984 |
[Atypical acute dystonia].
Topics: Acute Disease; Adult; Antipsychotic Agents; Aphonia; Dyskinesia, Drug-Induced; Dystonia; Humans; Mal | 1998 |
Excessive use of anticholinergic drugs in a sub-sample of Italian schizophrenics.
Topics: Adult; Biperiden; Female; Humans; Italy; Male; Middle Aged; Orphenadrine; Parasympatholytics; Patien | 1991 |
Residual neuroleptic-induced parkinsonian symptoms in schizophrenia. A naturalistic study with orphenadrine.
Topics: Adult; Aged; Female; Haloperidol; Humans; Male; Middle Aged; Orphenadrine; Parkinson Disease, Second | 1989 |
Orphenadrine plasma levels and amelioration of extrapyramidal side effects in schizophrenic patients treated with haloperidol.
Topics: Adolescent; Adult; Basal Ganglia Diseases; Female; Haloperidol; Humans; Male; Middle Aged; Orphenadr | 1986 |
Serum tryptophan binding in chlorpromazine-treated chronic schizophrenics.
Topics: Chlorpromazine; Chronic Disease; Diffusion; Fatty Acids, Nonesterified; Humans; Liver; Male; Orphena | 1974 |
[The high dosage reserpine cure in the treatment of chronic schizophrenics. A clinical and statistical analysis].
Topics: Adolescent; Adult; Age Factors; Aged; Autonomic Nervous System; Chronic Disease; Female; Humans; Mal | 1968 |
Clinical observations on the therapeutic activity of flupentixol in the treatment of chronic schizophrenia.
Topics: Adult; Aged; Blood; Body Weight; Chlorpromazine; Chronic Disease; Delusions; Depression, Chemical; F | 1970 |
[Very high reserpine dosage in the treatment of chronic schizophrenia].
Topics: Chronic Disease; Female; Humans; Male; Orphenadrine; Reserpine; Schizophrenia | 1967 |
Fluphenazine enanthate in the maintenance treatment of schizophrenia.
Topics: Fluphenazine; Humans; Orphenadrine; Procyclidine; Schizophrenia | 1968 |
Psychiatric complications of amphetamine substances.
Topics: Adolescent; Adult; Amitriptyline; Amphetamine; Chlordiazepoxide; Depression; Ephedrine; Female; Hall | 1966 |
A controlled trial of anti-Parkinson drugs in drug-induced Parkinsonism.
Topics: Adolescent; Adult; Chlorpromazine; Haloperidol; Humans; Middle Aged; Orphenadrine; Parasympatholytic | 1966 |