orphenadrine has been researched along with Pain in 12 studies
Orphenadrine: A muscarinic antagonist used to treat drug-induced parkinsonism and to relieve pain from muscle spasm.
orphenadrine : A tertiary amino compound which is the phenyl-o-tolylmethyl ether of 2-(dimethylamino)ethanol.
Pain: An unpleasant sensation induced by noxious stimuli which are detected by NERVE ENDINGS of NOCICEPTIVE NEURONS.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Frequency, duration of muscle cramps, and pain score improved significantly after 1 month of orphenadrine therapy in comparison to placebo." | 9.34 | Orphenadrine in treatment of muscle cramps in cirrhotic patients: a randomized study. ( Abd-Elsalam, S; Alkhalawany, W; Badawi, R; Ebrahim, S; Elfert, A; Elkadeem, M; Hawash, N; Soliman, S, 2020) |
| "Frequency, duration of muscle cramps, and pain score improved significantly after 1 month of orphenadrine therapy in comparison to placebo." | 5.34 | Orphenadrine in treatment of muscle cramps in cirrhotic patients: a randomized study. ( Abd-Elsalam, S; Alkhalawany, W; Badawi, R; Ebrahim, S; Elfert, A; Elkadeem, M; Hawash, N; Soliman, S, 2020) |
| "The aim of this study was to investigate the analgesic efficacy of Neodolpasse, a fixed-dose combination of orphenadrine and diclofenac, compared with those of its single active ingredients in a human pain model." | 5.11 | Comparison of the analgesic effects of a fixed-dose combination of orphenadrine and diclofenac (Neodolpasse) with its single active ingredients diclofenac and orphenadrine: a placebo-controlled study using laser-induced somatosensory-evoked potentials fro ( Eggenreich, U; Gschanes, A; Reitmeir, P; Schaffler, K, 2005) |
| "The clinical efficacy and tolerability of a combination preparation ('Norgesic') of 35 mg orphenadrine plus 450 mg paracetamol was compared with that of placebo in a controlled double-blind, parallel group, 7-day study comprising 44 patients suffering from pain due to tension of the cervical and upper thoracic musculature." | 5.05 | Effect of a combination of orphenadrine/paracetamol tablets ('Norgesic') on myalgia: a double-blind comparison with placebo in general practice. ( Høivik, HO; Moe, N, 1983) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 10 (83.33) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (8.33) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (8.33) | 2.80 |
| Authors | Studies |
|---|---|
| Abd-Elsalam, S | 1 |
| Ebrahim, S | 1 |
| Soliman, S | 1 |
| Alkhalawany, W | 1 |
| Elfert, A | 1 |
| Hawash, N | 1 |
| Elkadeem, M | 1 |
| Badawi, R | 1 |
| MOODY, WM | 1 |
| HODDES, SH | 1 |
| Schaffler, K | 1 |
| Reitmeir, P | 1 |
| Gschanes, A | 1 |
| Eggenreich, U | 1 |
| Cohen, L | 1 |
| McGuinness, BW | 1 |
| Høivik, HO | 3 |
| Moe, N | 2 |
| Osmundsen, K | 2 |
| Argyropoulos, G | 1 |
| Clarici, G | 1 |
| Heppner, F | 1 |
| Gundersen, R | 1 |
| Hunskaar, S | 1 |
| Berge, OG | 1 |
| Hole, K | 1 |
| Batterman, RC | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Randomized Study of Orphenadrine' in the Treatment of Muscle Cramps in Patients With Cirrhosis[NCT02423395] | Phase 3 | 100 participants (Anticipated) | Interventional | 2015-01-31 | Recruiting | ||
| Clinical Response of Nuberol Forte® for the Pain Management in Musculoskeletal Disorders in Routine Pakistani Practice[NCT04765787] | 399 participants (Actual) | Observational | 2020-11-25 | Completed | |||
| Neodolpasse® Infusion Solution Versus Diclofenac 75 mg Infusion in the Treatment of Postoperative Pain After Elective Knee Surgery - an Exploratory Placebo-controlled Clinical Study to Investigate the Analgesic Properties of the Combination of Diclofenac [NCT03493490] | Phase 4 | 72 participants (Actual) | Interventional | 2018-03-01 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
7 trials available for orphenadrine and Pain
| Article | Year |
|---|---|
Orphenadrine in treatment of muscle cramps in cirrhotic patients: a randomized study.
Topics: Humans; Liver Cirrhosis; Muscle Cramp; Orphenadrine; Pain; Treatment Outcome | 2020 |
Comparison of the analgesic effects of a fixed-dose combination of orphenadrine and diclofenac (Neodolpasse) with its single active ingredients diclofenac and orphenadrine: a placebo-controlled study using laser-induced somatosensory-evoked potentials fro
Topics: Adult; Analgesics; Capsaicin; Cross-Over Studies; Diclofenac; Double-Blind Method; Drug Combinations | 2005 |
A double-blind comparison in general practice of a combination tablet containing orphenadrine citrate and paracetamol ('Norgesic') with paracetamol alone.
Topics: Acetaminophen; Adolescent; Adult; Aged; Back Pain; Bone Diseases; Double-Blind Method; Drug Combinat | 1983 |
[Effect of orphenadrine/paracetamol combination tablets (Norgesic) on myalgia. A double-blind comparative study using a placebo in general practice].
Topics: Acetaminophen; Adult; Clinical Trials as Topic; Double-Blind Method; Drug Combinations; Female; Huma | 1983 |
Effect of a combination of orphenadrine/paracetamol tablets ('Norgesic') on myalgia: a double-blind comparison with placebo in general practice.
Topics: Acetaminophen; Adolescent; Adult; Aged; Double-Blind Method; Drug Combinations; Female; Humans; Male | 1983 |
[Combined analgesics in myalgia of the neck. A double-blind comparison of paracetamol and orphenadrine (Norgesic) and paracetamol and codeine (Paralgin forte) in general practice].
Topics: Acetaminophen; Adolescent; Adult; Aged; Aspirin; Caffeine; Clinical Trials as Topic; Codeine; Double | 1986 |
Methodology of analgesic-muscle relaxant evaluation. Experience with orphenadrine citrate compound.
Topics: Adult; Aspirin; Caffeine; Clinical Trials as Topic; Female; Humans; Male; Muscles; Orphenadrine; Pai | 1965 |
5 other studies available for orphenadrine and Pain
| Article | Year |
|---|---|
EFFECTIVE OFFICE MANAGEMENT OF PAINFUL TRAUMATIC MUSCLE INJURIES.
Topics: Biomedical Research; Drug Therapy; Humans; Muscle Cramp; Muscular Diseases; Office Management; Orphe | 1964 |
ORPHENADRINE CITRATE IN THE TREATMENT OF MUSCULAR PAIN.
Topics: Back Pain; Biomedical Research; Drug Therapy; Fibromyalgia; Muscle Relaxants, Central; Muscular Dise | 1964 |
Efficiency of a muscle relaxant-analgesic combination in general practice.
Topics: Acetaminophen; Humans; Muscles; Orphenadrine; Pain | 1967 |
[Infusion therapy of pain in a series of neurological-neurosurgical patients].
Topics: Analgesics; Aspartic Acid; Dipyrone; Drug Combinations; Female; Humans; Magnesium; Male; Orphenadrin | 1976 |
Orphenadrine citrate increases and prolongs the antinociceptive effects of paracetamol in mice.
Topics: Acetaminophen; Animals; Drug Administration Schedule; Drug Synergism; Drug Therapy, Combination; Mal | 1986 |