orphenadrine has been researched along with Drug Overdose in 5 studies
Orphenadrine: A muscarinic antagonist used to treat drug-induced parkinsonism and to relieve pain from muscle spasm.
orphenadrine : A tertiary amino compound which is the phenyl-o-tolylmethyl ether of 2-(dimethylamino)ethanol.
Drug Overdose: Accidental or deliberate use of a medication or street drug in excess of normal dosage.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Orphenadrine has complex pharmacokinetic properties and a narrow therapeutic index." | 2.40 | [Clinical pharmacology of anticholinergic antiparkinson agents. A review with emphasis on acute toxicity]. ( Gjerden, P; Slørdal, L, 1998) |
| "Orphenadrine is an antimuscarinic agent mainly used for the treatment of parkinsonism and to alleviate the neuroleptic syndrome induced by antipsychotic drugs." | 1.35 | Determination of orphenadrine plasma levels using HPLC with diode array detection and a novel solid-phase extraction procedure in psychiatric patients. ( Franchini, L; Petio, C; Raggi, MA; Saracino, MA; Vitali, M, 2009) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (20.00) | 18.7374 |
| 1990's | 3 (60.00) | 18.2507 |
| 2000's | 1 (20.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Saracino, MA | 1 |
| Petio, C | 1 |
| Vitali, M | 1 |
| Franchini, L | 1 |
| Raggi, MA | 1 |
| Gjerden, P | 2 |
| Engelstad, KS | 1 |
| Pettersen, G | 1 |
| Slørdal, L | 2 |
| Millar, WM | 1 |
| Henderson, RA | 1 |
| Lane, S | 1 |
| Henry, JA | 1 |
1 review available for orphenadrine and Drug Overdose
| Article | Year |
|---|---|
[Clinical pharmacology of anticholinergic antiparkinson agents. A review with emphasis on acute toxicity].
Topics: Antiparkinson Agents; Benztropine; Biperiden; Drug Overdose; Humans; Muscle Relaxants, Central; Orph | 1998 |
4 other studies available for orphenadrine and Drug Overdose
| Article | Year |
|---|---|
Determination of orphenadrine plasma levels using HPLC with diode array detection and a novel solid-phase extraction procedure in psychiatric patients.
Topics: Antipsychotic Agents; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Drug M | 2009 |
[Fatalities caused by anticholinergic antiparkinsonian drugs. Analysis of findings in a 11-year national material].
Topics: Adolescent; Adult; Aged; Antiparkinson Agents; Autopsy; Drug Overdose; Humans; Middle Aged; Muscle R | 1998 |
Deaths after overdoses of orphenadrine.
Topics: Cause of Death; Drug Interactions; Drug Overdose; Haloperidol; Humans; Orphenadrine; Phenothiazines | 1977 |
Life-threatening ventricular arrhythmia (torsades de pointes) after haloperidol overdose.
Topics: Drug Overdose; Electrocardiography; Female; Haloperidol; Humans; Middle Aged; Orphenadrine; Torsades | 1991 |