Page last updated: 2024-11-02

orphenadrine and Clasp-Knife Spasticity

orphenadrine has been researched along with Clasp-Knife Spasticity in 5 studies

Orphenadrine: A muscarinic antagonist used to treat drug-induced parkinsonism and to relieve pain from muscle spasm.
orphenadrine : A tertiary amino compound which is the phenyl-o-tolylmethyl ether of 2-(dimethylamino)ethanol.

Research Excerpts

ExcerptRelevanceReference
"One patient with severe spastic hypertonia leading to triple flexion when the limb was manipulated did not gain any relief with orphenadrine."2.68Reduction of spastic hypertonia in patients with spinal cord injury: a double-blind comparison of intravenous orphenadrine citrate and placebo. ( Buonocore, M; Casale, R; Glynn, CJ, 1995)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19904 (80.00)18.7374
1990's1 (20.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Steinbrecher, W1
McGuinness, BW1
Casale, R1
Glynn, CJ1
Buonocore, M1
Hartmann-von Monakow, K1
Lenman, JA1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Clinical Response of Nuberol ForteĀ® for the Pain Management in Musculoskeletal Disorders in Routine Pakistani Practice[NCT04765787]399 participants (Actual)Observational2020-11-25Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

2 trials available for orphenadrine and Clasp-Knife Spasticity

ArticleYear
A double-blind comparison in general practice of a combination tablet containing orphenadrine citrate and paracetamol ('Norgesic') with paracetamol alone.
    The Journal of international medical research, 1983, Volume: 11, Issue:1

    Topics: Acetaminophen; Adolescent; Adult; Aged; Back Pain; Bone Diseases; Double-Blind Method; Drug Combinat

1983
Reduction of spastic hypertonia in patients with spinal cord injury: a double-blind comparison of intravenous orphenadrine citrate and placebo.
    Archives of physical medicine and rehabilitation, 1995, Volume: 76, Issue:7

    Topics: Adult; Cross-Over Studies; Double-Blind Method; Female; Humans; Injections, Intravenous; Leg; Male;

1995

Other Studies

3 other studies available for orphenadrine and Clasp-Knife Spasticity

ArticleYear
[Myotonolysis by means of orphenadrine citrate. Clinical and electromyographic studies in cerebral and spinal spasticity].
    Arzneimittel-Forschung, 1966, Volume: 16, Issue:2

    Topics: Action Potentials; Automatism; Central Nervous System Diseases; Citrates; Electromyography; Humans;

1966
[Therapy of spastic syndromes].
    Bibliotheca psychiatrica et neurologica, 1969, Volume: 139

    Topics: Carisoprodol; Chlordiazepoxide; Chlormezanone; Chlorzoxazone; Curare; Diazepam; Guaifenesin; Humans;

1969
The use of drugs in the treatment of spasticity.
    Proceedings of the Royal Society of Medicine, 1970, Volume: 63, Issue:9

    Topics: Chlordiazepoxide; Curare; Diazepam; Electromyography; Humans; Mephenesin; Muscle Spasticity; Orphena

1970