orotic acid has been researched along with Thiamine Deficiency in 5 studies
Orotic Acid: An intermediate product in PYRIMIDINE synthesis which plays a role in chemical conversions between DIHYDROFOLATE and TETRAHYDROFOLATE.
orotic acid : A pyrimidinemonocarboxylic acid that is uracil bearing a carboxy substituent at position C-6.
Thiamine Deficiency: A nutritional condition produced by a deficiency of THIAMINE in the diet, characterized by anorexia, irritability, and weight loss. Later, patients experience weakness, peripheral neuropathy, headache, and tachycardia. In addition to being caused by a poor diet, thiamine deficiency in the United States most commonly occurs as a result of alcoholism, since ethanol interferes with thiamine absorption. In countries relying on polished rice as a dietary staple, BERIBERI prevalence is very high. (From Cecil Textbook of Medicine, 19th ed, p1171)
| Excerpt | Relevance | Reference |
|---|---|---|
| "The effect of thiamine deficiency on rat brain DNA and RNA synthesis was investigated." | 7.65 | Reversible impairment of cerebral DNA synthesis in thiamine deficiency. ( Henderson, GI; Schenker, S, 1975) |
| "The effect of thiamine deficiency on rat brain DNA and RNA synthesis was investigated." | 3.65 | Reversible impairment of cerebral DNA synthesis in thiamine deficiency. ( Henderson, GI; Schenker, S, 1975) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Khokha, AM | 2 |
| Fustochenko, BP | 2 |
| Ostrovskiĭ, IuM | 1 |
| Nefedov, LI | 1 |
| Glader, BE | 1 |
| Sullivan, DW | 1 |
| Henderson, GI | 1 |
| Schenker, S | 1 |
| Baker, SJ | 1 |
1 review available for orotic acid and Thiamine Deficiency
| Article | Year |
|---|---|
The red blood cell as a biopsy tool.
Topics: Biopsy; Carbohydrate Metabolism, Inborn Errors; Erythrocytes; Galactosemias; Gout; Humans; Immunolog | 1981 |
4 other studies available for orotic acid and Thiamine Deficiency
| Article | Year |
|---|---|
[Peculiarities of nucleotide and nucleic acid metabolism in hydroxythiamine-induced vitamin B1 deficiency].
Topics: Adenosine Triphosphate; Animals; DNA; Liver; Male; NAD; NADP; Nucleotides; Orotic Acid; Oxythiamine; | 1984 |
[Synthesis of nucleic RNA in hydroxythiamine-induced vitamin B1 deficiency].
Topics: Animals; Liver; Male; Methionine; Orotic Acid; Oxythiamine; Protein Biosynthesis; Rats; RNA; RNA, Tr | 1984 |
Reversible impairment of cerebral DNA synthesis in thiamine deficiency.
Topics: Adenine; Animals; Brain; Brain Diseases; Carbon Radioisotopes; DNA; Female; Hypothermia; Organ Size; | 1975 |
Nutrition and diseases of the blood: the megaloblastic anaemias.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Adult; Anemia, Macrocytic; Anemia, Megalo | 1975 |