orotic acid has been researched along with Syndrome in 9 studies
Orotic Acid: An intermediate product in PYRIMIDINE synthesis which plays a role in chemical conversions between DIHYDROFOLATE and TETRAHYDROFOLATE.
orotic acid : A pyrimidinemonocarboxylic acid that is uracil bearing a carboxy substituent at position C-6.
Syndrome: A characteristic symptom complex.
| Excerpt | Relevance | Reference |
|---|---|---|
| "According to results of clinical and instrumental investigation magnesium orotate (50 mg/day during first week and 25 mg/day thereafter) was found to be effective therapy of children with syndrome of cardiac connective tissue dysplasia (mainly with mitral valve prolapse and anomalous chordae tendineae)." | 7.73 | [Clinical value of the use of magnesium orotate in adolescents with syndrome of cardiac connective tissue dysplasia]. ( D'iachenko, AV; Domnitskaia, TM; Domnitskiĭ, MV; Kupriianova, OO, 2005) |
| "Two patients with neonatal onset of hyperornithinemia-hyperammonemia-homocitrullinuria syndrome were studied at 4 and 2 1/2 yr of age, respectively." | 7.67 | Hyperornithinemia-hyperammonemia-homocitrullinuria syndrome: low creatine excretion and effect of citrulline, arginine, or ornithine supplement. ( Bachmann, C; Colombo, JP; Dionisi Vici, C; Gambarara, M; Sabetta, G, 1987) |
| "Impairment of urea cycle function in hyperornithinemia-hyperammonemia-homocitrullinuria syndrome is presumably caused, in some patients, by deficient transport of ornithine from cytoplasm into mitochondria." | 7.67 | Ornithine loading did not prevent induced hyperammonemia in a patient with hyperornithinemia-hyperammonemia-homocitrullinuria syndrome. ( Clow, CL; Mackenzie, S; Scriver, CR; Simell, O, 1985) |
| "According to results of clinical and instrumental investigation magnesium orotate (50 mg/day during first week and 25 mg/day thereafter) was found to be effective therapy of children with syndrome of cardiac connective tissue dysplasia (mainly with mitral valve prolapse and anomalous chordae tendineae)." | 3.73 | [Clinical value of the use of magnesium orotate in adolescents with syndrome of cardiac connective tissue dysplasia]. ( D'iachenko, AV; Domnitskaia, TM; Domnitskiĭ, MV; Kupriianova, OO, 2005) |
| "Two patients with neonatal onset of hyperornithinemia-hyperammonemia-homocitrullinuria syndrome were studied at 4 and 2 1/2 yr of age, respectively." | 3.67 | Hyperornithinemia-hyperammonemia-homocitrullinuria syndrome: low creatine excretion and effect of citrulline, arginine, or ornithine supplement. ( Bachmann, C; Colombo, JP; Dionisi Vici, C; Gambarara, M; Sabetta, G, 1987) |
| "Impairment of urea cycle function in hyperornithinemia-hyperammonemia-homocitrullinuria syndrome is presumably caused, in some patients, by deficient transport of ornithine from cytoplasm into mitochondria." | 3.67 | Ornithine loading did not prevent induced hyperammonemia in a patient with hyperornithinemia-hyperammonemia-homocitrullinuria syndrome. ( Clow, CL; Mackenzie, S; Scriver, CR; Simell, O, 1985) |
| "A young patient with hepatocellular carcinoma receiving chemotherapy presented with encephalopathy." | 1.35 | Postchemotherapy hyperammonemic encephalopathy emulating ornithine transcarbamoylase (OTC) deficiency. ( Blanke, CD; Chan, JS; Harding, CO, 2008) |
| "Orotic aciduria was present (max: 693 mg/day) and was related to NH4 levels." | 1.25 | [Chronic hyperammonemia with orotic aciduria: evidence of pyrimidine pathway stimulation (author's transl)]. ( Beaudry, MA; Collu, R; Dallairf, L; Ducharme, JR; Leboeuf, G; Letarte, J; Melancon, SB, 1975) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (66.67) | 18.7374 |
| 1990's | 1 (11.11) | 18.2507 |
| 2000's | 2 (22.22) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| DIOGUARDI, N | 1 |
| SECCHI, GC | 1 |
| Domnitskaia, TM | 1 |
| D'iachenko, AV | 1 |
| Kupriianova, OO | 1 |
| Domnitskiĭ, MV | 1 |
| Chan, JS | 1 |
| Harding, CO | 1 |
| Blanke, CD | 1 |
| Salerno, C | 1 |
| D'Eufemia, P | 1 |
| Celli, M | 1 |
| Finocchiaro, R | 1 |
| Crifò, C | 1 |
| Giardini, O | 1 |
| Beaudry, MA | 1 |
| Letarte, J | 1 |
| Collu, R | 1 |
| Leboeuf, G | 1 |
| Ducharme, JR | 1 |
| Melancon, SB | 1 |
| Dallairf, L | 1 |
| Ratkiewicz, A | 1 |
| Galasinski, W | 1 |
| Dionisi Vici, C | 1 |
| Bachmann, C | 1 |
| Gambarara, M | 1 |
| Colombo, JP | 1 |
| Sabetta, G | 1 |
| Rottem, M | 1 |
| Statter, M | 1 |
| Amit, R | 1 |
| Brand, N | 1 |
| Bujanover, Y | 1 |
| Yatziv, S | 1 |
| Simell, O | 1 |
| Mackenzie, S | 1 |
| Clow, CL | 1 |
| Scriver, CR | 1 |
9 other studies available for orotic acid and Syndrome
| Article | Year |
|---|---|
[Notes on a case of edematigenous complex deficiency syndrome in a gastrectomized subject; combined potassium orotate and vitamin E therapy].
Topics: Deficiency Diseases; Gastrectomy; Humans; Orotic Acid; Syndrome; Vitamin E | 1958 |
[Clinical value of the use of magnesium orotate in adolescents with syndrome of cardiac connective tissue dysplasia].
Topics: Adolescent; Blood Pressure; Child; Chordae Tendineae; Connective Tissue Diseases; Female; Follow-Up | 2005 |
Postchemotherapy hyperammonemic encephalopathy emulating ornithine transcarbamoylase (OTC) deficiency.
Topics: Adult; Arginine; Carcinoma, Hepatocellular; Citrulline; Female; Glutamine; Hepatic Encephalopathy; H | 2008 |
Determination of urinary orotic acid and uracil by capillary zone electrophoresis.
Topics: Amino Acid Metabolism, Inborn Errors; Ammonia; Borates; Buffers; Citrulline; Dietary Proteins; Elect | 1999 |
[Chronic hyperammonemia with orotic aciduria: evidence of pyrimidine pathway stimulation (author's transl)].
Topics: Alanine; Amino Acids; Ammonia; Child, Preschool; Dietary Proteins; Erythrocytes; Growth Disorders; H | 1975 |
Structural and metabolic characterization of RNAs from rats with experimental Guerin tumor - II. metabolic peculiarities of RNAs from the liver and tumor tissues of rats.
Topics: Animals; Carbon Radioisotopes; Carcinoma, Squamous Cell; Liver; Neoplasms, Experimental; Orotic Acid | 1976 |
Hyperornithinemia-hyperammonemia-homocitrullinuria syndrome: low creatine excretion and effect of citrulline, arginine, or ornithine supplement.
Topics: Amino Acid Metabolism, Inborn Errors; Ammonia; Arginine; Child, Preschool; Citrulline; Creatine; Fem | 1987 |
Clinical and laboratory study in 22 patients with inherited hyperammonemic syndromes.
Topics: Amino Acid Metabolism, Inborn Errors; Ammonia; Child; Coma; Female; Humans; Male; Orotic Acid; Pedig | 1986 |
Ornithine loading did not prevent induced hyperammonemia in a patient with hyperornithinemia-hyperammonemia-homocitrullinuria syndrome.
Topics: Alanine; Amino Acid Metabolism, Inborn Errors; Amino Acids; Ammonia; Child; Citrulline; Cytoplasm; H | 1985 |