orotic acid has been researched along with Rett Syndrome in 3 studies
Orotic Acid: An intermediate product in PYRIMIDINE synthesis which plays a role in chemical conversions between DIHYDROFOLATE and TETRAHYDROFOLATE.
orotic acid : A pyrimidinemonocarboxylic acid that is uracil bearing a carboxy substituent at position C-6.
Rett Syndrome: An inherited neurological developmental disorder that is associated with X-LINKED INHERITANCE and may be lethal in utero to hemizygous males. The affected female is normal until the age of 6-25 months when progressive loss of voluntary control of hand movements and communication skills; ATAXIA; SEIZURES; autistic behavior; intermittent HYPERVENTILATION; and HYPERAMMONEMIA appear. (From Menkes, Textbook of Child Neurology, 5th ed, p199)
| Excerpt | Relevance | Reference |
|---|---|---|
| "The in vivo functioning of the urea cycle in the Rett syndrome (RS) was investigated using alanine load test." | 7.68 | The urea cycle in the Rett syndrome. ( Hjelm, M; Oberholzer, V; Thomas, S; Wilson, J, 1990) |
| "The in vivo functioning of the urea cycle in the Rett syndrome (RS) was investigated using alanine load test." | 3.68 | The urea cycle in the Rett syndrome. ( Hjelm, M; Oberholzer, V; Thomas, S; Wilson, J, 1990) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Pineda, M | 1 |
| Vilaseca, MA | 1 |
| Vernet, A | 1 |
| Campistol, J | 1 |
| Mas, A | 1 |
| Fabrega, C | 1 |
| Carpenter, KH | 1 |
| Bonham, JR | 1 |
| Clarke, A | 1 |
| Thomas, S | 1 |
| Oberholzer, V | 1 |
| Wilson, J | 1 |
| Hjelm, M | 1 |
1 trial available for orotic acid and Rett Syndrome
| Article | Year |
|---|---|
the allopurinol test in patients with Rett syndrome.
Topics: Acids; Adolescent; Allopurinol; Amino Acids; Child; Citrulline; Female; Humans; Ornithine Carbamoylt | 1993 |
2 other studies available for orotic acid and Rett Syndrome
| Article | Year |
|---|---|
Rett's syndrome and ornithine carbamoyltransferase deficiency.
Topics: Alanine; Ammonia; Female; Humans; Ornithine Carbamoyltransferase Deficiency Disease; Orotic Acid; Re | 1990 |
The urea cycle in the Rett syndrome.
Topics: Adult; Ammonia; Child; Child, Preschool; Female; Humans; Middle Aged; Orotic Acid; Rett Syndrome; Ur | 1990 |