Page last updated: 2024-10-19

orotic acid and Pregnancy

orotic acid has been researched along with Pregnancy in 82 studies

Orotic Acid: An intermediate product in PYRIMIDINE synthesis which plays a role in chemical conversions between DIHYDROFOLATE and TETRAHYDROFOLATE.
orotic acid : A pyrimidinemonocarboxylic acid that is uracil bearing a carboxy substituent at position C-6.

Pregnancy: The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH.

Research Excerpts

ExcerptRelevanceReference
" The use of antihypertensive, metabolic (magnesium orotate) drugs, sedative and uroseptic phytotherapy, application of other nondrug measures in conditions of multidisciplinary dynamic support of the gestational period facilitated regress of clinical symptoms of EHT and EHT+CTD, favorable course of pregnancy and successful delivery."9.17[Magnesium orotate in treatment of chronic hypertension in pregnant women]. ( Gaĭsin, IR; Iskhakova, AS; Khodyrev, LA; Maksimov, NI; Shilina, LV; Valeeva, RM, 2013)
"Our objective was to study the urinary levels of orotic acid in normal pregnancy and in pregnancy-induced hypertension."7.70Urinary orotic acid levels in normal pregnancy and pregnancy-induced hypertension. ( Furutani, K; Ito, M; Matsubara, K; Ochi, H; Togari, H, 2000)
" The use of antihypertensive, metabolic (magnesium orotate) drugs, sedative and uroseptic phytotherapy, application of other nondrug measures in conditions of multidisciplinary dynamic support of the gestational period facilitated regress of clinical symptoms of EHT and EHT+CTD, favorable course of pregnancy and successful delivery."5.17[Magnesium orotate in treatment of chronic hypertension in pregnant women]. ( Gaĭsin, IR; Iskhakova, AS; Khodyrev, LA; Maksimov, NI; Shilina, LV; Valeeva, RM, 2013)
"Relative deficiencies of ornithine or arginine occur in the presence of excessive ammonia, excessive lysine, growth, pregnancy, trauma, or protein deficiency and malnutrition."4.77Conditional deficiencies of ornithine or arginine. ( Zieve, L, 1986)
"Our objective was to study the urinary levels of orotic acid in normal pregnancy and in pregnancy-induced hypertension."3.70Urinary orotic acid levels in normal pregnancy and pregnancy-induced hypertension. ( Furutani, K; Ito, M; Matsubara, K; Ochi, H; Togari, H, 2000)
"Groups of normal and heterozygote sparse-fur (spf) mutant mice were studied at various stages of gestation, to assess the effects of normal pregnancy on orotate excretion, hepatic mitochondrial urea cycle enzymes and any predisposition to the development of fatty liver."3.67The role of hepatic ornithine transcarbamylase deficiency in the orotic aciduria of pregnant mice. ( Letarte, J; Qureshi, IA; Qureshi, SR; Tuchweber, B; Yousef, I, 1986)
" The method was used to measure orotic acid and orotidine in urine samples from newborns, healthy controls and patients with gout or deficiency of hypoxanthine-guanine phosphoribosyltransferase receiving allopurinol."3.66The urinary excretion of orotic acid and orotidine, measured by an isotope dilution assay. ( Schretlen, ED; Tax, WJ; Veerkamp, JH, 1978)
"Aberrant fetal programming in gestational diabetes mellitus seems to increase the risk of obesity, type 2 diabetes, and cardiovascular disease."1.62Early pregnancy metabolites predict gestational diabetes mellitus: implications for fetal programming. ( Gornbein, JA; Koos, BJ, 2021)
"We demonstrated previously (Cancer Res."1.27Absence of the cancer-associated factor with a molecular weight of 60,000 from the plasma of patients with a spectrum of nonneoplastic conditions. ( Hanausek-Walaszek, ME; Schumm, DE; Walaszek, Z; Webb, TE, 1984)
"Orotic acid was minimally used by both fetal and placental tissues."1.27Incorporation of labeled ribonucleic acid precursors into maternal and fetal rat tissues during pregnancy. ( Dorko, ME; Hayashi, TT, 1986)

Research

Studies (82)

TimeframeStudies, this research(%)All Research%
pre-199071 (86.59)18.7374
1990's5 (6.10)18.2507
2000's4 (4.88)29.6817
2010's1 (1.22)24.3611
2020's1 (1.22)2.80

Authors

AuthorsStudies
Koos, BJ1
Gornbein, JA1
Gaĭsin, IR1
Valeeva, RM1
Maksimov, NI1
Iskhakova, AS1
Khodyrev, LA1
Shilina, LV1
Závaczki, Z1
Szöllõsi, J1
Kiss, SA1
Koloszár, S1
Fejes, I1
Kovács, L1
Pál, A1
GAFFURI, S1
JOHKE, T1
D AVOSSA, T1
KARNOFSKY, DA1
BASCH, RS1
Tanner, L1
Näntö-Salonen, K1
Niinikoski, H1
Erkkola, R1
Huoponen, K1
Simell, O1
Sakatoku, J1
Ebisuta, K1
Kitayama, T1
Yoshida, O1
Shimizu, Y1
Roberge, A1
Charbonneau, R1
Berlinguet, L1
Sereni, F1
Sereni, LP1
Tomasi, V1
Barnabei, O1
Raisz, LG1
Niemann, I1
Gubskiĭ, IuI1
Radzinskiĭ, VE1
Smal'ko, PIa1
Korniushina, TV1
Götz, D1
Ziesch, C1
Wenzel, M1
Grosse, G1
Schuster, T1
Wenzel, J1
Visek, WJ4
Jakobs, C1
Sweetman, L1
Nyhan, WL2
Gruenke, L1
Craig, JC1
Wadman, SK1
Nagasaki, T1
Tiemeyer, W1
Stohrer, M1
Giesecke, D1
Robinson, JL2
Dombrowski, DB1
Clark, JH1
Shanks, RD1
Schumm, DE1
Hanausek-Walaszek, ME1
Walaszek, Z1
Webb, TE1
Glasgow, AM1
Larsen, JW1
Alumot, E1
Bruckental, I1
Tadmor, A1
Kennit, C1
Holstein, P1
Ng, WG1
Oizumi, J1
Koch, R1
Shaw, KN1
McLaren, J1
Donnel, GN1
Carter, M1
Ohba, S1
Kidouchi, K2
Toyama, J1
Oda, T1
Tsuboi, T1
Ichiki, T1
Sobajima, H1
Sugiyama, N1
Morishita, H1
Købayashi, M1
Batshaw, ML1
Yudkoff, M1
McLaughlin, BA1
Gorry, E1
Anegawa, NJ1
Smith, IA1
Hyman, SL1
Robinson, MB1
Sumi, S1
Imaeda, M1
Asai, M1
Ito, T1
Wada, Y1
Furutani, K1
Ochi, H1
Matsubara, K1
Ito, M1
Togari, H1
Kavardzhikova, S1
Tax, WJ1
Veerkamp, JH1
Schretlen, ED1
Lipp, K1
van der Meulen, N1
Wenske, G1
Linneweh, F1
Milner, JA1
Fox, IH1
Mckerns, KW2
Ryschkewitsch, W1
Larson, BL3
Rashid, R1
Baker, SJ1
Easter, RA2
Baker, DH2
Bensen, JT1
Nelson, LH1
Pettenati, MJ1
Block, SM1
Brusilow, SW1
Livingstone, LR1
Burton, BK1
Fairbanks, LD1
Duley, JA1
Shores, AJ1
Simmonds, HA1
Dorko, ME1
Hayashi, TT5
Motyl, T2
Zieve, L1
Wahab, IM1
Anderson, RR1
Qureshi, IA1
Letarte, J1
Tuchweber, B1
Yousef, I1
Qureshi, SR1
Barej, W1
Leontowicz, H1
Dancis, J1
Matousek, J1
Grozdanovic, J1
Holtzman, NA1
Kintzel, HW3
Hirsch, GH1
Hook, JB1
Lee, CJ1
Schwartz, AL1
Lafarge, C1
Frayssinet, C1
Shearer, RW1
Bakay, B1
Janakidevi, K1
Smith, MJ1
Katz, RS1
MacFarlane, K1
O'Sullivan, WJ2
Schwarze, R2
Hinkel, GK2
Cutroneo, KR1
Bresnick, E3
Wood, MH1
Miller, BG1
Eckles, SG1
Lanclos, KD1
Krooth, RS1
Sell, EK1
Srivastava, U1
Vu, ML1
Bhargava, S1
Goswami, T1
Short, RD1
Rao, KS1
Gibson, JE1
Chen, MH1
Zimmerman, EF1
Andrew, F1
Kalter, H1
Shin, DH2
Wiand, S2
Kemmer, C1
Roschlau, G1
Garvey, BI1
Kinsella, JE2
Okonkwo, PO1
Lanclos, K1
Gonzales, E1
Erdos, T1
Bessada, R1
Raska, K1
Zedeck, MS1
Welch, AD1

Reviews

6 reviews available for orotic acid and Pregnancy

ArticleYear
Ammonia: its effects on biological systems, metabolic hormones, and reproduction.
    Journal of dairy science, 1984, Volume: 67, Issue:3

    Topics: Ammonia; Animals; Cats; Cattle; Chickens; Cricetinae; Dietary Proteins; Dogs; Estrus; Female; Guinea

1984
An update of concepts of essential amino acids.
    Annual review of nutrition, 1984, Volume: 4

    Topics: Amino Acid Metabolism, Inborn Errors; Amino Acids, Essential; Ammonia; Animals; Arginine; Atrophy; C

1984
Inborn errors of purine and pyrimidine metabolism.
    Clinics in perinatology, 1976, Volume: 3, Issue:1

    Topics: Animals; Female; Heterozygote; Humans; Lesch-Nyhan Syndrome; Orotic Acid; Pregnancy; Prenatal Diagno

1976
Conditional deficiencies of ornithine or arginine.
    Journal of the American College of Nutrition, 1986, Volume: 5, Issue:2

    Topics: Amino Acids; Amino Acids, Branched-Chain; Ammonia; Animals; Arginine; Citrulline; Female; Glycine; H

1986
Dietary treatment of inborn errors of metabolism.
    Annual review of medicine, 1970, Volume: 21

    Topics: Ammonia; Carbohydrate Metabolism, Inborn Errors; Diet Therapy; Female; Fructose; Galactosemias; Glyc

1970
Orotic acid.
    Australian and New Zealand journal of medicine, 1973, Volume: 3, Issue:4

    Topics: Allopurinol; Anemia, Pernicious; Animals; Azauridine; Carboxy-Lyases; Fatty Liver; Female; Humans; I

1973

Trials

3 trials available for orotic acid and Pregnancy

ArticleYear
[Magnesium orotate in treatment of chronic hypertension in pregnant women].
    Kardiologiia, 2013, Volume: 53, Issue:9

    Topics: Adult; Antihypertensive Agents; Blood Pressure; Connective Tissue Diseases; Dietary Supplements; Dru

2013
Magnesium-orotate supplementation for idiopathic infertile male patients: a randomized, placebo-controlled clinical pilot study.
    Magnesium research, 2003, Volume: 16, Issue:2

    Topics: Adult; Dietary Supplements; Female; Humans; Infertility, Male; Magnesium; Male; Orotic Acid; Pilot P

2003
[Clinical trial of Magnerot in the treatment of a threatened abortion after a previous delivery].
    Akusherstvo i ginekologiia, 2000, Volume: 40, Issue:4

    Topics: Abortion, Threatened; Administration, Oral; Adult; Bulgaria; Drug Evaluation; Female; Humans; Obstet

2000

Other Studies

73 other studies available for orotic acid and Pregnancy

ArticleYear
Early pregnancy metabolites predict gestational diabetes mellitus: implications for fetal programming.
    American journal of obstetrics and gynecology, 2021, Volume: 224, Issue:2

    Topics: Adult; Alanine; Arginine; Carnitine; Case-Control Studies; Diabetes, Gestational; Diet Therapy; Dopa

2021
[Possibilities of orotic acid in the therapy and prevention of various hypoprotein myelopathies of pregnancy].
    Minerva ginecologica, 1960, Aug-31, Volume: 12

    Topics: Biomedical Research; Bone Marrow; Bone Marrow Diseases; Female; Humans; Orotic Acid; Pregnancy; Preg

1960
ACID-SOLUBLE NUCLEOTIDES OF COLOSTRUM, MILK, AND MAMMARY GLAND.
    Journal of biochemistry, 1963, Volume: 54

    Topics: Adenine Nucleotides; Animals; Cattle; Chromatography; Colostrum; Cytosine Nucleotides; Female; Goats

1963
[EXPERIMENTAL RESEARCH ON THE EFFECT OF OROTIC ACID IN PREGNANCY].
    Minerva ginecologica, 1965, May-15, Volume: 17

    Topics: Animals; Female; Humans; Lipids; Liver; Orotic Acid; Pregnancy; Pregnancy, Animal; Rats; Research

1965
Effects of 5-fluorodeoxyuridine and related halogenated pyrimidines on the sand-dollar embryo.
    The Journal of biophysical and biochemical cytology, 1960, Volume: 7

    Topics: Cytidine; DNA; Female; Floxuridine; Fluorouracil; Humans; Orotic Acid; Pregnancy; Pyrimidines; Thymi

1960
Hazards associated with pregnancies and deliveries in lysinuric protein intolerance.
    Metabolism: clinical and experimental, 2006, Volume: 55, Issue:2

    Topics: Adult; Amino Acid Transport Disorders, Inborn; Amino Acids, Diamino; Blood Pressure; Female; Hemoglo

2006
[The treatment of male infertility with some medicaments].
    Hinyokika kiyo. Acta urologica Japonica, 1966, Volume: 12, Issue:8

    Topics: Adult; Female; Humans; Infertility, Male; Male; Orotic Acid; Pregnancy; Ubiquinone; Vitamin B 12; Vi

1966
Variation of the enzymes of the urea cycle and aspartate transcarbamylase in liver of pregnant rats.
    Canadian journal of biochemistry, 1967, Volume: 45, Issue:9

    Topics: Animals; Arginase; Female; Ligases; Liver; Lyases; Male; Ornithine Carbamoyltransferase; Orotic Acid

1967
Synthesis and breakdown of rat liver RNA during the neonatal period.
    Archives of biochemistry and biophysics, 1967, Volume: 121, Issue:2

    Topics: Animals; Animals, Newborn; Carbon Isotopes; Cell Nucleus; Female; Liver; Microsomes; Nitrogen; Oroti

1967
Early effects of parathyroid hormone and thyrocalcitonin on bone in organ culture.
    Nature, 1967, Apr-29, Volume: 214, Issue:5087

    Topics: Animals; Biological Transport; Bone and Bones; Bone Resorption; Calcitonin; Calcium; Calcium Isotope

1967
[Protein-synthesizing apparatus of the rat liver and placenta during damage of the biomembrane by tetrachloromethane and the administration of methylxanthines].
    Voprosy meditsinskoi khimii, 1984, Volume: 30, Issue:6

    Topics: Aminophylline; Animals; Carbon Tetrachloride; Cyclic AMP; Female; Leucine; Liver; Male; Microsomes,

1984
[Electron microscopic and morphometric studies on the in vitro differentiation of mitochondria in neurons of hippocampus explant cultures as affected by orotic acid and sodium orotate].
    Zeitschrift fur mikroskopisch-anatomische Forschung, 1982, Volume: 96, Issue:4

    Topics: Animals; Cell Differentiation; Culture Techniques; Female; Hippocampus; Microscopy, Electron; Mitoch

1982
Stable isotope dilution analysis of orotic acid and uracil in amniotic fluid.
    Clinica chimica acta; international journal of clinical chemistry, 1984, Nov-15, Volume: 143, Issue:2

    Topics: Amniotic Fluid; Argininosuccinate Synthase; Chromatography, Liquid; Female; Gas Chromatography-Mass

1984
[Ammonia metabolism during perinatal period--ontogenesis of enzymes in pyrimidine biosynthesis and urea cycle system].
    Nihon Sanka Fujinka Gakkai zasshi, 1984, Volume: 36, Issue:12

    Topics: Aging; Ammonia; Animals; Animals, Newborn; Aspartate Carbamoyltransferase; Carbamoyl-Phosphate Synth

1984
Metabolites of nucleic acids in bovine milk.
    Journal of dairy science, 1984, Volume: 67, Issue:4

    Topics: Allantoin; Animals; Cattle; Chromatography, High Pressure Liquid; Female; Lactation; Milk; Milk Prot

1984
Orotate in milk and urine of dairy cows with a partial deficiency of uridine monophosphate synthase.
    Journal of dairy science, 1984, Volume: 67, Issue:5

    Topics: Animals; Carboxy-Lyases; Cattle; Cattle Diseases; Colostrum; Female; Lactation; Milk; Multienzyme Co

1984
Absence of the cancer-associated factor with a molecular weight of 60,000 from the plasma of patients with a spectrum of nonneoplastic conditions.
    Cancer research, 1984, Volume: 44, Issue:1

    Topics: Adult; Aged; Amniotic Fluid; Animals; Biological Assay; Blood Proteins; Electrophoresis, Polyacrylam

1984
Urinary orotic acid in pregnancy.
    American journal of obstetrics and gynecology, 1984, Jun-15, Volume: 149, Issue:4

    Topics: Adult; Female; Humans; Orotic Acid; Pregnancy

1984
Effect of proline on arginine uptake and nitrogen metabolism of lactating goats.
    Journal of dairy science, 1983, Volume: 66, Issue:6

    Topics: Animals; Arginine; Diet; Female; Goats; Lactation; Milk; Milk Proteins; Nitrogen; Orotic Acid; Pregn

1983
Carrier detection of urea cycle disorders.
    Pediatrics, 1981, Volume: 68, Issue:3

    Topics: Amino Acid Metabolism, Inborn Errors; Ammonia; Argininosuccinate Synthase; Citrulline; Female; Genet

1981
Quantitative analysis of amniotic fluid pyrimidines for the prenatal diagnosis of hereditary orotic aciduria.
    Journal of inherited metabolic disease, 1993, Volume: 16, Issue:5

    Topics: Amniotic Fluid; Chromatography, High Pressure Liquid; Female; Humans; Infant, Newborn; Metabolism, I

1993
The sparse fur mouse as a model for gene therapy in ornithine carbamoyltransferase deficiency.
    Gene therapy, 1995, Volume: 2, Issue:10

    Topics: Amino Acid Metabolism, Inborn Errors; Amino Acids; Ammonia; Animals; Avoidance Learning; Crosses, Ge

1995
Urinary orotic acid in healthy adults and patients with various diseases.
    Clinica chimica acta; international journal of clinical chemistry, 1997, Oct-31, Volume: 266, Issue:2

    Topics: Adult; Female; Humans; Male; Middle Aged; Orotic Acid; Pregnancy

1997
Urinary orotic acid levels in normal pregnancy and pregnancy-induced hypertension.
    Gynecologic and obstetric investigation, 2000, Volume: 50, Issue:1

    Topics: Arginine; Female; Gestational Age; Humans; Hypertension; Nitric Oxide; Orotic Acid; Pregnancy; Pregn

2000
The urinary excretion of orotic acid and orotidine, measured by an isotope dilution assay.
    Clinica chimica acta; international journal of clinical chemistry, 1978, Dec-15, Volume: 90, Issue:3

    Topics: Adolescent; Adult; Aging; Allopurinol; Breast Feeding; Child; Female; Gout; Humans; Hypoxanthine Pho

1978
Orotic acid: its influence on nuclear RNA and microsomal protein synthesis in brain cells of undernourished rat pups.
    Biology of the neonate, 1978, Volume: 33, Issue:1-2

    Topics: Animals; Animals, Newborn; Brain; Cell Nucleus; Female; Microsomes; Nerve Tissue Proteins; Nutrition

1978
Orotic aciduria in the female rat and its relation to dietary arginine.
    The Journal of nutrition, 1978, Volume: 108, Issue:8

    Topics: Aging; Ammonia; Animals; Arginine; Birth Weight; Body Weight; Citrates; Female; Litter Size; Orotic

1978
Regulation of RNA synthesis in corpora lutea nucleic by luteinizing hormone and derivatives.
    Biochimica et biophysica acta, 1976, Nov-12, Volume: 454, Issue:1

    Topics: Animals; Cattle; Cell Nucleus; Chymotrypsin; Corpus Luteum; Enzyme Activation; Female; Glucosephosph

1976
Comparative production of beta-lactoglobulin and orotic acid with lactose in bovine mammary cell cultures: effects of cell density and constituent inhibition.
    Journal of dairy science, 1976, Volume: 59, Issue:11

    Topics: Animals; Cattle; Cells, Cultured; Female; Lactation; Lactoglobulins; Lactose; Mammary Glands, Animal

1976
Acid-soluble purine and pyrimidine derivatives in cow's milk produced on normal feed and almost protein-free-feed with urea as the main nitrogen source.
    Die Nahrung, 1976, Volume: 20, Issue:10

    Topics: Animal Feed; Animals; Cattle; Cytosine Nucleotides; Dietary Proteins; Female; Lactation; Milk; Nucle

1976
Nutrition and diseases of the blood: the megaloblastic anaemias.
    Progress in food & nutrition science, 1975, Volume: 1, Issue:7-8

    Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Adult; Anemia, Macrocytic; Anemia, Megalo

1975
Nitrogen metabolism and reproductive response of gravid swine fed an arginine-free diet during the last 84 days of gestation.
    The Journal of nutrition, 1976, Volume: 106, Issue:5

    Topics: Animals; Arginine; Birth Weight; Blood Urea Nitrogen; Body Weight; Deficiency Diseases; Female; Hemo

1976
First report of management and outcome of pregnancies associated with hereditary orotic aciduria.
    American journal of medical genetics, 1991, Dec-15, Volume: 41, Issue:4

    Topics: Abnormalities, Multiple; Adult; Chromosome Aberrations; Chromosomes, Human, Pair 11; Chromosomes, Hu

1991
HPLC assay of uridine monophosphate synthase (UMPS) in chorionic villus samples (CVS) and erythrocytes (RBC).
    Advances in experimental medicine and biology, 1991, Volume: 309B

    Topics: Chorionic Villi; Chromatography, High Pressure Liquid; Erythrocytes; Female; Humans; Multienzyme Com

1991
Incorporation of labeled ribonucleic acid precursors into maternal and fetal rat tissues during pregnancy.
    American journal of obstetrics and gynecology, 1986, Volume: 154, Issue:4

    Topics: Animals; Cytidine; Female; Fetus; Injections, Intravenous; Maternal-Fetal Exchange; Nucleic Acid Pre

1986
Arginine needs, physiological state and usual diets. A reevaluation.
    The Journal of nutrition, 1986, Volume: 116, Issue:1

    Topics: Animals; Arginine; Body Weight; Creatine; Diet; Fatty Liver; Female; Humans; Lysine; Nutritional Req

1986
The urinary excretion of orotic acid and urea in dairy cows in early lactation.
    Zentralblatt fur Veterinarmedizin. Reihe A, 1986, Volume: 33, Issue:3

    Topics: Animals; Cattle; Female; Lactation; Orotic Acid; Pregnancy; Urea

1986
Orotic acid in guinea pig milk: changes in concentration during lactation.
    Journal of dairy science, 1988, Volume: 71, Issue:9

    Topics: Animals; Female; Guinea Pigs; Lactation; Milk; Orotic Acid; Pregnancy; Time Factors

1988
The role of hepatic ornithine transcarbamylase deficiency in the orotic aciduria of pregnant mice.
    European journal of obstetrics, gynecology, and reproductive biology, 1986, Volume: 22, Issue:3

    Topics: Animals; Creatinine; Fatty Liver; Female; Genotype; Liver; Mice; Mice, Mutant Strains; Mitochondria,

1986
The orotic acid concentration in the blood, milk, and urine of dairy cows fed with urea supplemented diet.
    Archiv fur Tierernahrung, 1986, Volume: 36, Issue:6

    Topics: Animal Feed; Animals; Cattle; Female; Food, Fortified; Lactation; Milk; Orotic Acid; Pregnancy; Time

1986
Nutritional management of hereditary disorders.
    The Medical clinics of North America, 1970, Volume: 54, Issue:6

    Topics: Amino Acid Metabolism, Inborn Errors; Carbohydrate Metabolism, Inborn Errors; Diabetes Insipidus; Di

1970
Specific effect of bull seminal ribonuclease (AS RNase) on cell systems in mice.
    Comparative biochemistry and physiology. A, Comparative physiology, 1973, Oct-01, Volume: 46, Issue:2

    Topics: Animals; Carbon Radioisotopes; Cattle; Embryo, Mammalian; Female; Fluorescent Antibody Technique; Ge

1973
[Prevention of morbus haemolyticus neonatorum and of transitory hyperbilirubinemias of newborn infants through an enzyme inductor combination].
    Blut, 1973, Volume: 26, Issue:5

    Topics: Bilirubin; Drug Synergism; Enzyme Induction; Erythroblastosis, Fetal; Exchange Transfusion, Whole Bl

1973
Stimulation of renal organic acid transport and protein synthesis by penicillin.
    The Journal of pharmacology and experimental therapeutics, 1970, Volume: 174, Issue:1

    Topics: Aminohippuric Acids; Ammonium Chloride; Animals; Biological Transport, Active; Body Fluids; Body Wei

1970
Biosynthesis and characteristics of brain protein and ribonucleic acid in mice subjected to neonatal infection or undernutrition.
    The Journal of biological chemistry, 1970, Apr-25, Volume: 245, Issue:8

    Topics: Amino Acids; Animal Nutritional Physiological Phenomena; Animals; Animals, Newborn; Body Weight; Bra

1970
Influence of glucagon, 6-N,2'-O-dibutyryladenosine 3':5'-cyclic monophosphate and triamcinolone on the arginine synthetase system in perinatal rat liver.
    The Biochemical journal, 1972, Volume: 126, Issue:1

    Topics: Adenine Nucleotides; Animals; Carbon Isotopes; Citrulline; Cyclic AMP; Cycloheximide; Dactinomycin;

1972
[Minor role of the de novo pathway in the biosynthesis of RNA during fetal and neoplastic liver development in rats].
    Biochimie, 1972, Volume: 54, Issue:4

    Topics: Aflatoxins; Age Factors; Animals; Carcinoma, Hepatocellular; Cyclic AMP; Female; Glucagon; Injection

1972
Irreversibility of the alteration in RNA transport induced by an azo-dye carcinogen in the rat liver.
    Biochemical and biophysical research communications, 1974, Apr-08, Volume: 57, Issue:3

    Topics: Aging; Animals; Biological Transport; Carcinoma, Hepatocellular; Cell Nucleus; Cytoplasm; DNA, Neopl

1974
Effects of thalidomide and chlorcyclizine on the biosynthesis of nucleic acids and proteins in fetal and maternal tissues of the rat.
    The Journal of pharmacology and experimental therapeutics, 1970, Volume: 171, Issue:1

    Topics: Amino Acids; Animals; Carbon Isotopes; Chromatography, Thin Layer; Dactinomycin; DNA; Female; Fetus;

1970
Effects of salicylate on RNA polymerase activity and on the incorporation of orotic acid and thymidine into the nucleic acids of rat foetuses in vitro.
    The Journal of pharmacy and pharmacology, 1970, Volume: 22, Issue:4

    Topics: Abnormalities, Drug-Induced; Animals; Female; Fetal Death; Fetus; Nucleic Acids; Orotic Acid; Pregna

1970
Stimulation of RNA synthesis in corpora lutea nuclei by human chorionic gonadotropin in vitro.
    Biochimica et biophysica acta, 1974, May-31, Volume: 349, Issue:3

    Topics: Animals; Carbon Radioisotopes; Cell Fractionation; Cell Nucleus; Centrifugation, Density Gradient; C

1974
Nucleotide inhibition of post-orotate pyrimidine synthesis pathway enzymes of bovine mammary tissue.
    Journal of dairy science, 1974, Volume: 57, Issue:11

    Topics: Animals; Binding, Competitive; Carboxy-Lyases; Cattle; Enzyme Activation; Female; Lactation; Mammary

1974
Arginine: a dispensable amino acid for postpubertal growth and pregnancy of swine.
    Journal of animal science, 1974, Volume: 39, Issue:6

    Topics: Amino Acids; Animal Feed; Animals; Arginine; Blood Urea Nitrogen; Body Weight; Citrates; Feces; Fema

1974
Changes in the incorporation of different RNA precursors into the maternal liver during pregnancy.
    Nature, 1973, Nov-09, Volume: 246, Issue:5428

    Topics: Animals; Cell Nucleolus; Cell Nucleus; Cytidine; DNA-Directed RNA Polymerases; Female; Kinetics; Liv

1973
[Prevention of transitory hyperbilirubinemia of the premature and mature newborn infants and of the hemolytic disease of the newborn by an enzyme induction combination: phenobarbital-nikethamide].
    Schweizerische medizinische Wochenschrift, 1972, Sep-23, Volume: 102, Issue:38

    Topics: Bilirubin; Enzyme Induction; Erythroblastosis, Fetal; Exchange Transfusion, Whole Blood; Female; Hum

1972
Induction of benzpyrene hydroxylase in fetal liver explants by flavones and phenobarbital.
    Biochemical pharmacology, 1973, Mar-15, Volume: 22, Issue:6

    Topics: Animals; Benzopyrenes; Carbon Isotopes; Dimethyl Sulfoxide; DNA; Enzyme Induction; Female; Fetus; Fl

1973
The orotic aciduria of pregnancy.
    American journal of obstetrics and gynecology, 1973, May-01, Volume: 116, Issue:1

    Topics: Animals; Carboxy-Lyases; Contraceptives, Oral; Erythrocytes; Female; Humans; Orotic Acid; Pentosyltr

1973
Metabolism of RNA and pyrimidine nucleotides in the uterus during the early decidual cell reaction.
    The Journal of endocrinology, 1973, Volume: 59, Issue:2

    Topics: Animals; Carbon Radioisotopes; Castration; Cytidine; Cytosine Nucleotides; Decidua; DNA; Estradiol;

1973
Nuclear ribonucleic acid in embryonic rat liver.
    Biochemistry, 1967, Volume: 6, Issue:8

    Topics: Animals; Carbon Isotopes; Cell Nucleus; Centrifugation, Density Gradient; Chloramphenicol; Cyclohexi

1967
The action of Mendelian genes in human diploid cell strains.
    Journal of cellular physiology, 1970, Volume: 76, Issue:3

    Topics: Athetosis; Biopsy; Cell Differentiation; Cell Line; Chorea; Compulsive Behavior; Culture Media; Cult

1970
Metabolism of nucleic acids and protein in the liver, brain, and kidney of female rats subjected to dietary restriction during the period of gestation as well as the period of growth, gestation, and lactation.
    Canadian journal of physiology and pharmacology, 1972, Volume: 50, Issue:8

    Topics: Animals; Body Weight; Brain; Carbon Isotopes; Diet; Female; Kidney; Lactation; Leucine; Liver; Nucle

1972
The in vivo biosynthesis of DNA, RNA, and proteins by mouse embryos after a teratogenic dose of cyclophosphamide.
    Teratology, 1972, Volume: 6, Issue:2

    Topics: Abnormalities, Drug-Induced; Animals; Carbon Isotopes; Cyclophosphamide; DNA; Embryo, Mammalian; Fem

1972
Pyrimidine synthesis pathway enzymes and orotic acid in bovine mammary tissue.
    Journal of dairy science, 1971, Volume: 54, Issue:6

    Topics: Animals; Body Fluids; Carboxy-Lyases; Cattle; Female; Kidney; Lactation; Liver; Mammary Glands, Anim

1971
Glucocorticoid inhibition of RNA synthesis responsible for cleft palate in mice: a model.
    Proceedings of the National Academy of Sciences of the United States of America, 1970, Volume: 67, Issue:2

    Topics: Animals; Carbon Isotopes; Cleft Palate; Cycloheximide; Depression, Chemical; Female; Gestational Age

1970
Comparative in vivo studies of RNA synthesis in the fetal liver, placenta, and maternal liver.
    American journal of obstetrics and gynecology, 1969, Dec-15, Volume: 105, Issue:8

    Topics: Animals; Carbon Isotopes; Female; Fetus; Gestational Age; Liver; Orotic Acid; Placenta; Pregnancy; R

1969
[Side effects of orotic acid in premature infants].
    Kinderarztliche Praxis, 1970, Volume: 38, Issue:6

    Topics: Autopsy; Biopsy; Blood Coagulation Factors; Female; Humans; Hyperbilirubinemia; Infant, Newborn; Inf

1970
Placental transfer of orotic acid, uridine, and UMP. I. Comparison of acid-soluble and acid-insoluble counts.
    American journal of obstetrics and gynecology, 1968, Dec-15, Volume: 102, Issue:8

    Topics: Animals; Carbon Isotopes; Female; Fetus; Gestational Age; Liver; Maternal-Fetal Exchange; Orotic Aci

1968
Transplacental passage of nucleotides, nucleosides, and bases.
    American journal of obstetrics and gynecology, 1968, Dec-15, Volume: 102, Issue:8

    Topics: Alkalies; Animals; Carbon Isotopes; Colchicine; Female; Fetus; Fluorouracil; Injections, Intraperito

1968
Influence of orotic acid on caprine lipid metabolism.
    Comparative biochemistry and physiology, 1969, Volume: 28, Issue:2

    Topics: Animals; Fatty Acids; Female; Goats; Lactation; Lipid Metabolism; Lipoproteins; Orotic Acid; Phospho

1969
Orotic acid in food milk powders.
    The American journal of clinical nutrition, 1969, Volume: 22, Issue:5

    Topics: Animals; Female; Food Analysis; Lactation; Methods; Milk; Orotic Acid; Pregnancy; Spectrophotometry

1969
The biosynthesis of ribonucleic acid in the liver of the rat fetus, in vivo.
    Biochimica et biophysica acta, 1965, Dec-09, Volume: 108, Issue:4

    Topics: Animals; Chromatography, Ion Exchange; Cytosine Nucleotides; Female; Fetus; In Vitro Techniques; Liv

1965
The turnover of ribosomal RNA and soluble RNA in the rabbit uterus.
    Biochimica et biophysica acta, 1966, Dec-21, Volume: 129, Issue:3

    Topics: Animals; Female; Injections, Intravenous; Liver; Muscles; Myocardium; Orotic Acid; Pregnancy; Pregna

1966
Relationship between the metabolic effects and the pregnancy-interrupting property of 6-azauridine in mice.
    Biochemical pharmacology, 1966, Volume: 15, Issue:12

    Topics: Animals; Carbon Isotopes; Carboxy-Lyases; Embryo, Mammalian; Female; Fetus; Mice; Orotic Acid; Oxida

1966