orotic acid has been researched along with Porphyrias in 6 studies
Orotic Acid: An intermediate product in PYRIMIDINE synthesis which plays a role in chemical conversions between DIHYDROFOLATE and TETRAHYDROFOLATE.
orotic acid : A pyrimidinemonocarboxylic acid that is uracil bearing a carboxy substituent at position C-6.
Porphyrias: A diverse group of metabolic diseases characterized by errors in the biosynthetic pathway of HEME in the LIVER, the BONE MARROW, or both. They are classified by the deficiency of specific enzymes, the tissue site of enzyme defect, or the clinical features that include neurological (acute) or cutaneous (skin lesions). Porphyrias can be hereditary or acquired as a result of toxicity to the hepatic or erythropoietic marrow tissues.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Biserte, G | 1 |
| Holtzman, NA | 1 |
| Capusan, I | 1 |
| Opincaru, E | 1 |
| Bociat, T | 1 |
| Lazar, V | 1 |
| Moisi, IG | 1 |
| Nawata, H | 1 |
| Kato, K | 1 |
| Granick, S | 1 |
| Gajdos, A | 1 |
| Gajdos-Török, M | 1 |
| Palma-Carlos, A | 1 |
| Palma-Carlos, L | 1 |
2 reviews available for orotic acid and Porphyrias
| Article | Year |
|---|---|
[Natural history of molecular pathology].
Topics: Amino Acid Sequence; Animals; Base Sequence; Chromosome Aberrations; Chromosome Deletion; Crossing O | 1975 |
Dietary treatment of inborn errors of metabolism.
Topics: Ammonia; Carbohydrate Metabolism, Inborn Errors; Diet Therapy; Female; Fructose; Galactosemias; Glyc | 1970 |
4 other studies available for orotic acid and Porphyrias
| Article | Year |
|---|---|
[Purinor in the treatment of porphyria cutanea tarda].
Topics: Adenine; Adult; Alanine Transaminase; Aspartate Aminotransferases; Drug Combinations; Fructosephosph | 1974 |
Ribonucleic acid synthesis in porphyric rat liver induced by 3,5-dicarbethoxy-1,4-dihydrocollidine.
Topics: 5-Aminolevulinate Synthetase; Animals; Cell Nucleus; Centrifugation, Density Gradient; Dactinomycin; | 1973 |
The induction in vitro of the synthesis of delta-aminolevulinic acid synthetase in chemical porphyria: a response to certain drugs, sex hormones, and foreign chemicals.
Topics: Amides; Animals; Barbiturates; Chick Embryo; Culture Techniques; Enzyme Repression; Gonadal Steroid | 1966 |
Porphyria induced in rats by orotic acid and the effect of adenine-5'-monophosphoric acid.
Topics: Adenine Nucleotides; Adenosine Triphosphate; Animals; Erythrocytes; Feces; Levulinic Acids; Ligases; | 1966 |