orotic acid has been researched along with Obesity in 6 studies
Orotic Acid: An intermediate product in PYRIMIDINE synthesis which plays a role in chemical conversions between DIHYDROFOLATE and TETRAHYDROFOLATE.
orotic acid : A pyrimidinemonocarboxylic acid that is uracil bearing a carboxy substituent at position C-6.
Obesity: A status with BODY WEIGHT that is grossly above the recommended standards, usually due to accumulation of excess FATS in the body. The standards may vary with age, sex, genetic or cultural background. In the BODY MASS INDEX, a BMI greater than 30.0 kg/m2 is considered obese, and a BMI greater than 40.0 kg/m2 is considered morbidly obese (MORBID OBESITY).
| Excerpt | Relevance | Reference |
|---|---|---|
| "The activities of pathways for the biosynthesis of hippurate, urea and pyrimidines in hepatocytes isolated from lean livers were compared with those from three sources of fatty liver: a) the genetically obese Zucker rat, b) Sprague-Dawley rats fed a diet deficient in choline and inositol, and c) Sprague-Dawley rats fed a diet supplemented with orotic acid." | 7.67 | Biosynthesis of hippurate, urea and pyrimidines in the fatty liver: studies with rats fed orotic acid or a diet deficient in choline and inositol, and with genetically obese (Zucker) rats. ( Maswoswe, SM; Tremblay, GC, 1989) |
| "The purpose of this study was to ascertain the changes in nitrogen balance, plasma free amino acid concentrations, urinary orotic acid excretion and body weight during long-term fasting in adult obese cats." | 3.69 | Nitrogen balance, plasma free amino acid concentrations and urinary orotic acid excretion during long-term fasting in cats. ( Bee, D; Biourge, V; Fisher, C; Groff, JM; Morris, JG; Rogers, QR, 1994) |
| "The activities of pathways for the biosynthesis of hippurate, urea and pyrimidines in hepatocytes isolated from lean livers were compared with those from three sources of fatty liver: a) the genetically obese Zucker rat, b) Sprague-Dawley rats fed a diet deficient in choline and inositol, and c) Sprague-Dawley rats fed a diet supplemented with orotic acid." | 3.67 | Biosynthesis of hippurate, urea and pyrimidines in the fatty liver: studies with rats fed orotic acid or a diet deficient in choline and inositol, and with genetically obese (Zucker) rats. ( Maswoswe, SM; Tremblay, GC, 1989) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (66.67) | 18.7374 |
| 1990's | 2 (33.33) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Biourge, V | 2 |
| Groff, JM | 2 |
| Morris, JG | 2 |
| Rogers, QR | 2 |
| Fisher, C | 1 |
| Bee, D | 1 |
| Porta, EA | 1 |
| Bieri, JG | 1 |
| Evarts, RP | 1 |
| Maswoswe, SM | 1 |
| Tremblay, GC | 1 |
| Fillios, LC | 1 |
| Yokono, O | 1 |
1 review available for orotic acid and Obesity
| Article | Year |
|---|---|
Nutrition and diseases of the liver and gallbladder.
Topics: Alcoholism; Animals; Atrophy; Avitaminosis; Fatty Acids, Essential; Fatty Liver; Gallbladder Disease | 1975 |
5 other studies available for orotic acid and Obesity
| Article | Year |
|---|---|
Long-term voluntary fasting in adult obese cats: nitrogen balance, plasma amino acid concentrations and urinary orotic acid excretion.
Topics: Amino Acids; Animals; Cat Diseases; Cats; Fasting; Fatty Liver; Female; Male; Nitrogen; Obesity; Oro | 1994 |
Nitrogen balance, plasma free amino acid concentrations and urinary orotic acid excretion during long-term fasting in cats.
Topics: Amino Acids, Essential; Animals; Bilirubin; Body Weight; Cat Diseases; Cats; Fasting; Fatty Liver; F | 1994 |
Effect of plasma lipid levels and obesity on tissue stores of alpha-tocopherol.
Topics: Adipose Tissue; Animals; Cholesterol; Female; Lipids; Liver; Male; Muscles; Myocardium; Obesity; Oro | 1975 |
Biosynthesis of hippurate, urea and pyrimidines in the fatty liver: studies with rats fed orotic acid or a diet deficient in choline and inositol, and with genetically obese (Zucker) rats.
Topics: Ammonium Chloride; Animals; Benzoates; Choline Deficiency; Diet; Fatty Liver; Gluconeogenesis; Hippu | 1989 |
Hepatic RNA metabolism in male and female obese rats fed cholesterol.
Topics: Animals; Carbon Isotopes; Cell Nucleolus; Cell Nucleus; Cholesterol; Cytoplasm; DNA; Female; Genotyp | 1968 |