orotic acid has been researched along with Liver Neoplasms in 70 studies
Orotic Acid: An intermediate product in PYRIMIDINE synthesis which plays a role in chemical conversions between DIHYDROFOLATE and TETRAHYDROFOLATE.
orotic acid : A pyrimidinemonocarboxylic acid that is uracil bearing a carboxy substituent at position C-6.
Liver Neoplasms: Tumors or cancer of the LIVER.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Orotic acid (OA) has been intensively utilized to induce fatty liver in rats." | 5.56 | Orotic acid-treated hepatocellular carcinoma cells resist steatosis by modification of fatty acid metabolism. ( Käkelä, R; Matilainen, J; Mustonen, AM; Nieminen, P; Rilla, K; Sihvo, SP, 2020) |
| "Orotic acid (OA) has been intensively utilized to induce fatty liver in rats." | 1.56 | Orotic acid-treated hepatocellular carcinoma cells resist steatosis by modification of fatty acid metabolism. ( Käkelä, R; Matilainen, J; Mustonen, AM; Nieminen, P; Rilla, K; Sihvo, SP, 2020) |
| "A young patient with hepatocellular carcinoma receiving chemotherapy presented with encephalopathy." | 1.35 | Postchemotherapy hyperammonemic encephalopathy emulating ornithine transcarbamoylase (OTC) deficiency. ( Blanke, CD; Chan, JS; Harding, CO, 2008) |
| " To study the effects of PSC on liver cancer development, a daily dose of 30 mg PSC/kg body wt (PSC30) was chosen based on an initial dose-response experiment." | 1.32 | Effect of PSC 833, an inhibitor of P-glycoprotein, on 1,2-dimethylhydrazine-induced liver carcinogenesis in rats. ( Bradley, G; Kankesan, J; Laconi, E; Ling, V; Rajalakshmi, S; Rao, PM; Sarma, DS; Thiessen, JJ; Vanama, R; Yusuf, A, 2003) |
| "Orotic acid feeding was also associated with the tendency for development of larger mammary tumors induced by chemical carcinogens in rats and with development of urinary bladder calculi containing high concentrations of orotic acid in mice." | 1.28 | Nitrogen-stimulated orotic acid synthesis and nucleotide imbalance. ( Visek, WJ, 1992) |
| "Furthermore, Ehrlich ascites tumor cells indicating a high incorporation activity was also high in activities of both phosphorylase and kinase for uridine, while Rhodamine sarcoma as a representative having a low incorporation activity was considerably low in these two enzymic activities." | 1.26 | Incorporation characteristics of uracil, uridine, and orotic acid into ribonucleic acid of neoplastic cells. ( Tamemasa, O; Tezuka, M, 1977) |
| "In the two hepatomas the turnover of mRNA of free polyribosomes was at a similar rate as that of membrane bound polyribosomes." | 1.26 | Turnover of messenger RNA in transplantable hepatomas and host liver of rats. ( Murty, CN; Sidransky, H; Verney, E, 1978) |
| "Zajdela ascitic hepatoma cells are shown to take up pyrimidine bases at much lower rates than obtained in slices from normal rat liver." | 1.25 | Uptake in vitro of nucleic acid precursors and nucleic acids by Zajdela ascitic hepatoma cells. ( Bhargava, PM; Bornecque, CA; Szafarz, D; Zajdela, F, 1975) |
| "3." | 1.25 | Diversity and nature of ribosomal pools in hepatoma 7800 and host liver. ( Kwan, SW; Morris, HP; Webb, TE, 1968) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 62 (88.57) | 18.7374 |
| 1990's | 3 (4.29) | 18.2507 |
| 2000's | 3 (4.29) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 2 (2.86) | 2.80 |
| Authors | Studies |
|---|---|
| Matilainen, J | 1 |
| Mustonen, AM | 1 |
| Rilla, K | 1 |
| Käkelä, R | 1 |
| Sihvo, SP | 1 |
| Nieminen, P | 1 |
| Maji, M | 1 |
| Bhattacharya, I | 1 |
| Acharya, S | 1 |
| Chakraborty, MP | 1 |
| Gupta, A | 1 |
| Mukherjee, A | 1 |
| Kankesan, J | 1 |
| Yusuf, A | 1 |
| Laconi, E | 3 |
| Vanama, R | 1 |
| Bradley, G | 1 |
| Thiessen, JJ | 1 |
| Ling, V | 1 |
| Rao, PM | 6 |
| Rajalakshmi, S | 7 |
| Sarma, DS | 6 |
| REID, E | 1 |
| MANDEL, P | 1 |
| WINTZERITH, M | 1 |
| BORKOWSKA, I | 1 |
| MANDEL, L | 1 |
| BRESNICK, E | 2 |
| BLATCHFORD, K | 1 |
| JACOB, ST | 1 |
| BHARGAVA, PM | 2 |
| Koeberl, DD | 1 |
| Chan, JS | 1 |
| Harding, CO | 1 |
| Blanke, CD | 1 |
| Columbano, A | 1 |
| Ledda-Columbano, GM | 1 |
| Neal, GE | 1 |
| Metcalfe, SA | 1 |
| Legg, RF | 1 |
| Judah, DH | 1 |
| Green, JA | 1 |
| Rossiello, MR | 1 |
| Liau, MC | 1 |
| Hunt, ME | 1 |
| Hurlbert, RB | 1 |
| Porta, EA | 1 |
| Mitchell, AD | 1 |
| Hoogenraad, NJ | 2 |
| Szafarz, D | 1 |
| Bornecque, CA | 1 |
| Zajdela, F | 1 |
| Letnansky, K | 1 |
| Pausch, JG | 1 |
| Keppler, DO | 1 |
| Gerok, W | 2 |
| Tezuka, M | 1 |
| Tamemasa, O | 1 |
| Sidransky, H | 2 |
| Murty, CN | 1 |
| Verney, E | 2 |
| Keppler, D | 1 |
| Pausch, J | 1 |
| Lea, MA | 4 |
| Luke, A | 1 |
| Assad, A | 1 |
| Patel, M | 1 |
| Reddy, PA | 1 |
| Visek, WJ | 1 |
| Vasudevan, S | 1 |
| Narasimhan, S | 1 |
| Schachter, H | 1 |
| Harley, EH | 1 |
| Sacks, S | 1 |
| Berman, P | 1 |
| Cohen, L | 1 |
| Simmonds, HA | 1 |
| Fairbanks, LD | 1 |
| Black, D | 1 |
| Mack, P | 1 |
| Tranberg, KG | 1 |
| Strenram, U | 1 |
| Jeppsson, B | 1 |
| Widlus, D | 1 |
| Bengmark, S | 1 |
| Alam, A | 1 |
| Pala, M | 1 |
| Parodi, S | 1 |
| Boctor, A | 1 |
| Grossman, A | 1 |
| Goodman, JI | 1 |
| Potter, VR | 1 |
| Mayfield, ED | 1 |
| Lyman, K | 1 |
| Wilkinson, BR | 1 |
| Kirby, KS | 2 |
| Otsuka, H | 2 |
| Terayama, H | 3 |
| Webb, TE | 3 |
| Parish, JH | 1 |
| Drews, J | 1 |
| Brawerman, G | 1 |
| Morris, HP | 5 |
| Muramatsu, M | 1 |
| Higashinakagawa, T | 1 |
| Ono, T | 1 |
| Sugano, H | 1 |
| Matsudaira, H | 1 |
| Nakamura, C | 1 |
| Hishizawa, T | 1 |
| Kwan, SW | 1 |
| Rizzo, AJ | 1 |
| Miyamoto, M | 2 |
| Plagemann, PG | 1 |
| Dijkstra, J | 1 |
| Weide, SS | 1 |
| Shapot, VS | 1 |
| Vornovitskaya, GI | 1 |
| Gorozhanskaya, EG | 1 |
| Davidova, SY | 1 |
| Zhubanova, AA | 1 |
| Krechetova, GD | 1 |
| Chudinova, IA | 1 |
| Lafarge, C | 1 |
| Frayssinet, C | 1 |
| Sweeney, MJ | 3 |
| Hoffman, DH | 3 |
| Miller, S | 1 |
| Mackauf, I | 1 |
| Hirschberg, E | 1 |
| Van Buskirk, JJ | 1 |
| Kirsch, WM | 1 |
| Khalil, FL | 2 |
| Rey, MI | 1 |
| Winsnes, A | 1 |
| Rugstad, HE | 1 |
| Smuckler, EA | 1 |
| Koplitz, M | 1 |
| Shearer, RW | 1 |
| Lee, DC | 1 |
| Tidwell, T | 1 |
| Howard, E | 1 |
| Bullock, J | 1 |
| Parton, JW | 1 |
| Kröger, H | 2 |
| Lücking, T | 1 |
| Akao, M | 1 |
| Kuroda, K | 1 |
| Miyaki, K | 1 |
| Gronow, M | 1 |
| Nemoto, N | 1 |
| Takayama, S | 1 |
| Heidelberger, C | 1 |
| Lin, JK | 1 |
| Tung, TC | 1 |
| Kizer, DE | 1 |
| Clouse, JA | 1 |
| Agarwal, MK | 1 |
| Weinstein, IB | 1 |
| Kahle, P | 1 |
| Kessel, H | 1 |
5 reviews available for orotic acid and Liver Neoplasms
| Article | Year |
|---|---|
Nutrition and diseases of the liver and gallbladder.
Topics: Alcoholism; Animals; Atrophy; Avitaminosis; Fatty Acids, Essential; Fatty Liver; Gallbladder Disease | 1975 |
[Selective chemotherapy of hepatocellular carcinomas].
Topics: Animals; Carcinoma, Hepatocellular; Doxorubicin; Fluorouracil; Humans; Liver Neoplasms; Liver Neopla | 1978 |
Liver tumour promotion by chemicals: models and mechanisms.
Topics: Cell Division; Choline Deficiency; Cocarcinogenesis; Humans; Liver Neoplasms; Orotic Acid; Phenobarb | 1986 |
Notes on some peculiarities of enzymic processes in malignant tumours and tissues of the host.
Topics: Adenine; Animals; Carbon Isotopes; Carcinoma, Hepatocellular; Catalase; Cholesterol; DNA, Neoplasm; | 1972 |
Chemical carcinogenesis, chemotherapy: cancer's continuing core challenges--G. H. A. Clowes Memorial Lecture.
Topics: Animals; Antineoplastic Agents; Arginase; Benz(a)Anthracenes; Benzopyrenes; Carcinogens; Cell Divisi | 1970 |
65 other studies available for orotic acid and Liver Neoplasms
| Article | Year |
|---|---|
Orotic acid-treated hepatocellular carcinoma cells resist steatosis by modification of fatty acid metabolism.
Topics: Carcinoma, Hepatocellular; Discriminant Analysis; Fatty Acids; Gene Expression Regulation, Neoplasti | 2020 |
Hypoxia Active Platinum(IV) Prodrugs of Orotic Acid Selective to Liver Cancer Cells.
Topics: Antineoplastic Agents; Cell Hypoxia; Cell Line, Tumor; Cell Proliferation; Cell Survival; Dose-Respo | 2021 |
Effect of PSC 833, an inhibitor of P-glycoprotein, on 1,2-dimethylhydrazine-induced liver carcinogenesis in rats.
Topics: 1,2-Dimethylhydrazine; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Body Weight | 2003 |
Incorporation of orotic acid into ribonucleotides and ribonucleic acid by liver tumours.
Topics: Liver Neoplasms; Neoplasms; Nucleosides; Nucleotides; Orotic Acid; Ribonucleotides; RNA | 1958 |
[ON THE EXISTENCE OF RAPIDLY LABELED DESOXYRIBONUCLEIC FRACTION IN ANIMAL CELLS].
Topics: Adenine; Animals; Carbon Isotopes; Carcinoma, Hepatocellular; DNA; Liver; Liver Neoplasms; Neoplasm | 1964 |
STUDIES ON DIHYDROOROTASE ACTIVITY IN PREPARATIONS FROM NOVIKOFF ASCITES HEPATOMA CELLS.
Topics: Ascites; Carcinoma, Hepatocellular; Cyanides; Cysteine; Dihydroorotase; Enzyme Inhibitors; Hot Tempe | 1964 |
COMPARISON OF THE URACIL CATABOLIC ACTIVITY OF LIVER CELL SUSPENSIONS AND SLICES.
Topics: Carbon Dioxide; Carbon Isotopes; Carcinoma, Hepatocellular; Hepatocytes; Liver; Liver Neoplasms; Met | 1964 |
Vector-related tumorigenesis not found in ornithine transcarbamylase-deficient mice.
Topics: Adenoviridae; Animals; Genetic Therapy; Genetic Vectors; Humans; Liver Neoplasms; Mice; Ornithine Ca | 2006 |
Postchemotherapy hyperammonemic encephalopathy emulating ornithine transcarbamoylase (OTC) deficiency.
Topics: Adult; Arginine; Carcinoma, Hepatocellular; Citrulline; Female; Glutamine; Hepatic Encephalopathy; H | 2008 |
Occurrence of cell death (apoptosis) in preneoplastic and neoplastic liver cells. A sequential study.
Topics: Animals; Carcinogens; Cell Survival; Dimethylhydrazines; Liver; Liver Neoplasms; Liver Neoplasms, Ex | 1984 |
Mechanism of the resistance to cytotoxicity which precedes aflatoxin B1 hepatocarcinogenesis.
Topics: Aflatoxin B1; Aflatoxins; Animals; Carcinogens; Cell Survival; Cricetinae; DNA-Directed RNA Polymera | 1981 |
Induction of hepatic nodules in the rat by aristolochic acid.
Topics: Animals; Aristolochic Acids; Carcinogens; Cell Division; Cocarcinogenesis; Hepatectomy; Liver; Liver | 1993 |
Role of ribosomal RNA methylases in the regulation of ribosome production in mammalian cells.
Topics: Adenosine Triphosphate; Animals; Carcinoma, Hepatocellular; Cell Nucleolus; Hydrogen-Ion Concentrati | 1976 |
De novo pyrimidine nucleotide biosynthesis in synchronized rat hepatoma (HTC) cells and mouse embryo fibroblast (3T3) cells.
Topics: Animals; Aspartate Carbamoyltransferase; Carbamoyl-Phosphate Synthase (Ammonia); Carbon Dioxide; Car | 1975 |
Uptake in vitro of nucleic acid precursors and nucleic acids by Zajdela ascitic hepatoma cells.
Topics: Adenine; Animals; Biological Transport, Active; Carcinoma, Hepatocellular; Cell Line; DNA; DNA, Bact | 1975 |
The phosphorylation of nuclear proteins in the regenerating and premalignant rat liver and its significance for cell proliferation.
Topics: Animals; Binding Sites; Carcinoma, Hepatocellular; Cell Division; Cell Transformation, Neoplastic; C | 1975 |
Increased de novo pyrimidine nucleotide synthesis in liver induced by ammonium ions in amounts surpassing the urea cycle capacity.
Topics: Animals; Azauridine; Carbamoyl-Phosphate Synthase (Ammonia); Carbamoyl-Phosphate Synthase (Glutamine | 1977 |
Incorporation characteristics of uracil, uridine, and orotic acid into ribonucleic acid of neoplastic cells.
Topics: Adult; Aged; Animals; Carcinoma, Ehrlich Tumor; Carcinoma, Hepatocellular; Female; Humans; Liver; Li | 1977 |
Turnover of messenger RNA in transplantable hepatomas and host liver of rats.
Topics: Animals; Carcinoma, Hepatocellular; Dactinomycin; Female; Liver; Liver Neoplasms; Neoplasm Transplan | 1978 |
Inhibitory action of orotate, 2-thioorotate and isoorotate on nucleotide metabolism and nucleic acid synthesis in hepatoma cells.
Topics: Animals; Carcinoma, Hepatocellular; Cell Line; DNA, Neoplasm; Humans; Liver Neoplasms; Nucleotides; | 1992 |
Nitrogen-stimulated orotic acid synthesis and nucleotide imbalance.
Topics: Ammonia; Animals; Carbamyl Phosphate; Cattle; Humans; Liver Neoplasms; Milk; Orotic Acid; Pyrimidine | 1992 |
Complementarity between two rat liver tumor promoters.
Topics: Animals; Choline Deficiency; Diet; Diethylnitrosamine; gamma-Glutamyltransferase; Liver; Liver Neopl | 1987 |
Expression of N-acetylglucosaminyltransferase III in hepatic nodules during rat liver carcinogenesis promoted by orotic acid.
Topics: 1,2-Dimethylhydrazine; Animals; Cocarcinogenesis; Dimethylhydrazines; Enzyme Activation; Glucosyltra | 1988 |
Source and fate of circulating pyrimidines.
Topics: Aspartic Acid; Carbon Radioisotopes; Carcinoma, Hepatocellular; Cell Line; Chromatography, High Pres | 1986 |
RNA labelling with 3H-orotic acid and 3H-fluorouracil of rat liver tumour following transient hepatic arterial ischaemia.
Topics: Animals; DNA, Neoplasm; Fluorouracil; Hepatic Artery; Ischemia; Liver Neoplasms; Male; Orotic Acid; | 1988 |
Orotic acid, a promoter of liver carcinogenesis induces DNA damage in rat liver.
Topics: Animals; Carcinogens; DNA; Liver; Liver Neoplasms; Male; Orotic Acid; Rats; Rats, Inbred F344 | 1985 |
Differential sensitivity of rat liver and rat hepatoma cells to alpha-amanitin.
Topics: Adrenalectomy; Animals; Basidiomycota; Carbon Radioisotopes; Carcinoma, Hepatocellular; Cell Nucleus | 1973 |
The effect of 5-fluorodeoxyuridine on the synthesis of deoxyribonucleic acid pyrimidines in precancerous rat liver.
Topics: Aminohydrolases; Animals; Carbon Isotopes; Carcinogens; Cell Nucleus; Cytosine; DNA; Floxuridine; In | 1973 |
Incorporation of bicarbonate-14 C into pyrimidines and into ribonucleic acid of the Novikoff ascites tumor cell.
Topics: Ammonia; Animals; Aspartic Acid; Bicarbonates; Carcinoma, Hepatocellular; Chromatography, Ion Exchan | 1967 |
Studies in rapidly labelled ribonucleic acid in cell fractions and in tumour tissues.
Topics: Animals; Carcinoma, Ehrlich Tumor; Carcinoma, Hepatocellular; Centrifugation, Density Gradient; Live | 1966 |
Inhibition of DNA synthesis in ascites hepatoma cells by normal liver extract.
Topics: Animals; Azo Compounds; Carcinoma, Hepatocellular; DNA, Neoplasm; Electrophoresis; In Vitro Techniqu | 1966 |
Polyribosome breakdown in rat liver following administration of 8-azaguanine.
Topics: Animals; Azaguanine; Carbon Isotopes; Carcinoma, Hepatocellular; Dactinomycin; Liver; Liver Neoplasm | 1967 |
An extension of the naphthalene disulphonate method for mammalian nucleic acids.
Topics: Animals; Carcinoma, Ehrlich Tumor; Carcinoma, Hepatocellular; DNA; Liver; Liver Neoplasms; Mice; Nap | 1967 |
A growth regulating factor in rat liver.
Topics: Animals; Carbon Isotopes; Carcinoma, Hepatocellular; Cell Division; Culture Techniques; DNA; DNA Nuc | 1967 |
Nuclear RNA patterns in rat liver and hepatomas.
Topics: Animals; Carcinoma, Hepatocellular; Cell Nucleus; Chemical Phenomena; Chemistry; Hybridization, Gene | 1967 |
The nucleolar RNA of minimal deviation hepatomas.
Topics: Animals; Carbon Isotopes; Carcinoma, Hepatocellular; Cell Nucleolus; Centrifugation, Density Gradien | 1968 |
Some characteristics in the pathway of RNA synthesis in hepatoma cells.
Topics: Animals; Ascites; Autoradiography; Carbon Isotopes; Carcinoma, Hepatocellular; Liver Neoplasms; Male | 1968 |
Diversity and nature of ribosomal pools in hepatoma 7800 and host liver.
Topics: Animals; Azaguanine; Carbon Isotopes; Carbon Tetrachloride; Carcinoma, Hepatocellular; Dactinomycin; | 1968 |
Ribosome formation in rat liver: evidence for post-transcriptional control.
Topics: Animals; Anti-Bacterial Agents; Antimetabolites; Azaguanine; Carbon Isotopes; Carcinoma, Hepatocellu | 1969 |
Nature of rat liver cell sap factors inhibiting the DNA synthesis in tumour cells.
Topics: Animals; Animals, Newborn; Arginase; Carbon Isotopes; Carcinoma, Ehrlich Tumor; Carcinoma, Hepatocel | 1971 |
Nucleotide pools of Novikoff rat hepatoma cells growing in suspension culture. I. Kinetics of incorporation of nucleosides into nucleotide pools and pool sizes during growth cycle.
Topics: Animals; Aspartic Acid; Biological Transport; Carbon Isotopes; Carcinoma, Hepatocellular; Cell Line; | 1971 |
Changes in chromatin caused by aminoazo compounds.
Topics: Animals; Carbon Isotopes; Carcinoma, Hepatocellular; Centrifugation, Density Gradient; Chromatin; DN | 1972 |
Tumor cell sap factor stimulating orotate incorporation into nucleic acids in ascites hepatoma cells.
Topics: Aging; Animals; Animals, Newborn; Carbon Isotopes; Carcinoma, Hepatocellular; Cytoplasm; Diphosphate | 1972 |
[Minor role of the de novo pathway in the biosynthesis of RNA during fetal and neoplastic liver development in rats].
Topics: Aflatoxins; Age Factors; Animals; Carcinoma, Hepatocellular; Cyclic AMP; Female; Glucagon; Injection | 1972 |
Dihydroorotate dehydrogenase in liver and Morris hepatomas.
Topics: Animals; Carcinoma, Hepatocellular; Fasting; Hepatectomy; Hydrogen-Ion Concentration; Kinetics; Live | 1973 |
Orotate phosphoribosyl transferase and orotidylic acid decarboxylase activities in liver and Morris hepatomas.
Topics: Animals; Carbon Isotopes; Carcinoma, Hepatocellular; Hydro-Lyases; Hydrogen-Ion Concentration; Kinet | 1973 |
Action of miracil D and related compounds on DNA and RNA synthesis in regenerating liver and hepatomas.
Topics: Animals; Carcinoma, Hepatocellular; DNA; Hepatectomy; Liver Neoplasms; Liver Regeneration; Lucanthon | 1972 |
Loss of hepatoma ribosomal RNA during warfarin therapy.
Topics: Animals; Carbon Isotopes; Carcinoma, Hepatocellular; Cell Nucleus; Cytoplasm; Liver; Liver Neoplasms | 1973 |
Effects of formamidoxime on macromolecular synthesis in regenerating liver and hepatomas.
Topics: Amino Acids; Animals; Carcinoma, Hepatocellular; Cell Nucleus; Cytoplasm; Depression, Chemical; DNA; | 1973 |
Different properties of microsomal UDP-glucuronyltransferase in buffalo rat liver and a clonal strain of rat hepatoma cells derived from the same rat strain.
Topics: Animals; Carcinoma, Hepatocellular; Clone Cells; Coumarins; Digitonin; Edetic Acid; Female; Glucosam | 1973 |
Altered nuclear RNA transport associated with carcinogen intoxication in rats.
Topics: Animals; Biological Transport; Carbon Radioisotopes; Carcinoma, Hepatocellular; Cell Nucleus; Centri | 1973 |
Irreversibility of the alteration in RNA transport induced by an azo-dye carcinogen in the rat liver.
Topics: Aging; Animals; Biological Transport; Carcinoma, Hepatocellular; Cell Nucleus; Cytoplasm; DNA, Neopl | 1974 |
Effect of uridine on de novo pyrimidine biosynthesis in rat hepatoma cells in culture.
Topics: Amidohydrolases; Animals; Aspartate Carbamoyltransferase; Carbamates; Carbon Dioxide; Carbon Radiois | 1974 |
The thiolation, methylation, and formation of pseudouridine and dihydrouridine in tRNA of regenerating rat liver, human phytohemagglutinin stimulated lymphocytes, and Novikoff ascites cells.
Topics: Animals; Carbon Radioisotopes; Carcinoma, Hepatocellular; Cells, Cultured; Cysteine; Electrophoresis | 1972 |
Incorporation of precursors and inhibitors of nucleic acid synthesis into hepatomas and liver of the rat.
Topics: Amino Acids; Animals; Carbon Radioisotopes; Carcinoma, Hepatocellular; Cell Line; Fluorouracil; Inje | 1974 |
Biosynthesis of uridine-5'-monophosphate in rat liver and Morris hepatomas.
Topics: Amidohydrolases; Animals; Aspartate Carbamoyltransferase; Carboxy-Lyases; Carboxylic Acids; Carcinom | 1974 |
[Nucleic acid metabolism of rat liver during carcinogenesis with N-nitroso-morpholine].
Topics: Adenine Nucleotides; Animals; Carbon Isotopes; Carcinogens; Centrifugation, Zonal; Cytosine Nucleoti | 1967 |
Selective inhibition of RNA polymerase activity in rat liver nuclei by 4-(dimethylamino) azobenzene, and effect of nitrofurans on liver RNA metabolism associated with prevention of carcinogenesis.
Topics: Ammonium Sulfate; Animals; Carbon Isotopes; Cell Nucleus; Depression, Chemical; DNA; Enzyme Activati | 1972 |
Changes in the composition of rat liver chromatin fractions during diethylnitrosamine carcinogenesis.
Topics: Animals; Calcium; Chromatin; Electrophoresis, Polyacrylamide Gel; Liver; Liver Neoplasms; Molecular | 1972 |
Rapid loss of 7-methylguanine from liver nucleic acids in mice during the initial stage of liver carcinogenesis induced by dimethylnitrosamine.
Topics: Animals; Carbon Radioisotopes; Chromatography, Ion Exchange; DNA; Drinking Behavior; Guanine; Half-L | 1974 |
Effect of orotic acid on DAB-hepatocarcinogenesis in rats.
Topics: Animals; Liver Neoplasms; Neoplasms, Experimental; Orotic Acid; p-Dimethylaminoazobenzene; Rats | 1965 |
On relationships between induction of liver cancer with azo dyes and changes in nuclear RNA metabolism during carcinogenesis.
Topics: Adenine; Animals; Azo Compounds; Carbon Isotopes; Cell Nucleus; Diet; Female; Liver; Liver Neoplasms | 1969 |
Modifications of ribonucleic acid by chemical carcinogens. II. In vivo reaction of N-2-acetylaminofluorene with rat liver ribonucleic acid.
Topics: Animals; Carbon Isotopes; Carcinogens; Centrifugation, Density Gradient; Chromatography, DEAE-Cellul | 1970 |
Influence of orotic acid on liver tumorigenesis in rats ingesting ethionine, N-2-fluorenylacetamide, and 3'-methyl-dimethylaminoazobenzene.
Topics: Acetamides; Acetates; Amides; Animals; Azo Compounds; Benzene Derivatives; Body Weight; Diet; Diseas | 1970 |
[In vivo methylation of rat liver RNA and under the influence of diethylnitrosamine].
Topics: Animals; Carbon Isotopes; Carcinogens; Centrifugation, Zonal; Liver; Liver Neoplasms; Methionine; Me | 1968 |